1.A Case of Multiple Aneurysms due to Aortitis Syndrome.
Shinichi Suzuki ; Jiro Kondo ; Kiyotaka Imoto ; Michio Tobe ; Yoshihiro Iwai ; Masahiko Okamoto ; Mitsuchika Nakamura ; Yoshinori Takanashi ; Yoshiaki Inayama
Japanese Journal of Cardiovascular Surgery 2000;29(2):98-101
A 51-year-old man underwent arch replacement for a thoracic aortic succular aneurysm in December 1996. The pathological examination indicated aortitis to be the cause of the aneurysm. At that time we did not surgically treat the abdominal aortic aneurysm (AAA) which was only 32mm in diameter. Sixteen months after the first operation, he complained of a pulsatile tumor in his left leg. Angiography revealed an aneurysm of the left superficial femoral artery. The artery distal to the aneurysm was occluded, and the left popliteal artery received collateral blood flow from the deep femoral artery. The size of the AAA increased to 48mm, an indication of repair. Aneurysmectomy of the left superficial femoral artery and replacement of the abdominal aorta were performed simultaneously. The operative findings showed that the aneurysm of the left superficial femoral artery had been ruptured and formed a pseudoaneurysm. The pathological findings demonstrated both aneurysm aortitis. After the second operation, he was given steroid therapy to control the inflammatory reaction and he has been well for one year.
2.Intestinal ultrasound for intestinal Behçet disease reflects endoscopic activity and histopathological findings
Katsuki YAGUCHI ; Reiko KUNISAKI ; Sho SATO ; Kaori HIRAI ; Misato IZUMI ; Yoshimi FUKUNO ; Mami TANAKA ; Mai OKAZAKI ; Rongrong WU ; Yurika NISHIKAWA ; Yusuke MATSUNE ; Shunsuke SHIBUI ; Yoshinori NAKAMORI ; Masafumi NISHIO ; Mao MATSUBAYASHI ; Tsuyoshi OGASHIWA ; Ayako FUJII ; Kenichiro TORITANI ; Hideaki KIMURA ; Eita KUMAGAI ; Yukiko SASAHARA ; Yoshiaki INAYAMA ; Satoshi FUJII ; Toshiaki EBINA ; Kazushi NUMATA ; Shin MAEDA
Intestinal Research 2024;22(3):297-309
Background/Aims:
Intestinal Behçet disease is typically associated with ileocecal punched-out ulcers and significant morbidity and mortality. Intestinal ultrasound is a noninvasive imaging technique for disease monitoring. However, no previous reports have compared intestinal ultrasound with endoscopic ulcer activity or histopathological findings for intestinal Behçet disease. We evaluated the usefulness of intestinal ultrasound for assessing the activity of ileocecal ulcers in intestinal Behçet disease.
Methods:
We retrospectively compared intestinal ultrasound findings with 73 corresponding endoscopic images and 6 resected specimens. The intestinal ultrasound findings were assessed for 7 parameters (bowel wall thickness, vascularity [evaluated using the modified Limberg score with color Doppler], bowel wall stratification, white-plaque sign [strong hyperechogenic lines or spots], mesenteric lymphadenopathy, extramural phlegmons, and fistulas), and endoscopic ulcer activity was classified into active, healing, and scar stages. Histopathological findings were evaluated by consensus among experienced pathologists.
Results:
Bowel wall thickness (P< 0.001), vascularity (P< 0.001), loss of bowel wall stratification (P= 0.015), and white-plague sign (P= 0.013) were significantly exacerbated in the endoscopic active ulcer stage. Receiver operating characteristic curve analysis revealed that a bowel wall thickness of > 5.5 mm (sensitivity 89.7%, specificity 85.3%) was potentially useful for detecting active lesions. When compared with histopathological findings, an increase in bowel wall thickness reflected the ulcer marginal ridge, and the white-plaque sign reflected the ulcer bottom.
Conclusions
Intestinal ultrasound is useful for monitoring intestinal ulcer activity in intestinal Behçet disease.