As follow-up of Song's experiments reported previously, this study was undertaken to observe pathologic changes in Imuran-treated renal homografts in dogs. Mongrel dogs weighing 15 to 20 kilograms were used in all experiments. Renal transplants were exchanged between animals. Imuran was administered twice a day per oral with daily doses of 3mg. per kilogram of body weight, and the first dose was given 24 hours before renal transplantation. Transplanted kidney were removed on the postoperative 1st, 3rd, 7th, 14th. 20th, and 30th day, and the were examined microscopically with Hematoxylin-Eosin staining. As comparing with the results of Song's experiments which were untreated homotransplants, the appearance of characteristic microscopic changes of rejection (progressive destructive changes of vessels with infiltration of lymphocytes, polymorphonuclear leukocytes and plasma cell) was temporarily delayed and modified by Imuran administration, but ischemic changes developed imminently in later days.
Allografts* ; Animals ; Azathioprine ; Body Weight ; Dogs ; Follow-Up Studies ; Kidney ; Kidney Transplantation ; Lymphocytes ; Neutrophils ; Plasma

A statistical analysis was made on 124 cases of urinary calculi during the period from Jan. 1968 to Aug. 1971 on the Department of Urology of Capital Military Hospital, and the results were obtained as following; 1. The incidence of urinary: calculi was 2.04% of out-patients. 2. The age of the patients ranged from 20 to 30 years in approximately 75.8%. 3. A seasonal occurrence was a most high during summer on 41.6%. 4. The locational distribution of urinary calculi was 59.7% in ureter, 28. 2% in kidney, 8. 1% in bladder, 4.0% in urethra. Approximately 9. 1% of the upper urinary calculi was found bilaterally. 5. The most favored predirection of ureteral stone was lower one-third in 70.2% of all cases. 6. In a number of urinary calculi, 83.9% was single and 16.1% was more than 2. 7. The ureterolithotomy was performed on 40 of 80 cases requiring surgical intervention. Cystoscopic manipulation and conservative treatment were 13. 1% in the each. 8. The results of qualitative analysis of 73 urinary calculi showed calcium phosphate + oxalate in 49.3%, calcium phosphate in 16.4%, calcium oxalate in 15.1%, calcium carbonate in 8.2%, calcium phosphate + uric acid in 4.1%, calcium oxalate + urate in 4.1%, calcium phosphate +ammonium in 2.8%.
Calcium ; Calcium Carbonate ; Calcium Oxalate ; Calculi ; Hospitals, Military ; Humans ; Incidence ; Kidney ; Outpatients ; Seasons ; Statistics as Topic* ; Ureter ; Urethra ; Uric Acid ; Urinary Bladder ; Urinary Calculi ; Urolithiasis* ; Urology

Statistical observation was made on 1,512 out-patients and 71 in-patients in the Department of Urology, Capital Military Hospital during the period from January 1, 1970 to December 31, 1970.
Hospitals, Military* ; Humans ; Military Personnel* ; Outpatients ; Urology*

Clinical studies on thirteen patients with Behcet's syndrome who had visited during the period from Jan. 1970 to Sep. 1973, to the Department of Dermatology & Ophthahnology, Busan National University Hospital, were made and the following results obtained. 1) The ratio of male vs. female was l. 0: l. 6 with no definite sexual differences. The ages ranged from 17 to 56 years with the peak incidence in third decade of life. 2) The "complete" form consisting of oculo- oro-genital and cutaneous lesions appeared in . 4 patients (30. 8%) and the "incomplet" in 9 patients (69. 2%). 3) Aphthous stomatitis was most predominant, being observed in 12 out of all 13 cases (92.3%), the next was cutaneous manifestations such as erythema nodosum, pyodermas, acneiform & pustular lesions and erythema multiforme in 10 cases (76. 1%) and genital ulcers in 9 cascs (69.2%). Ocular lesions and articular involvements came fourth, each being found in 8 cases (61. 5%). 4) The commonest feature of ocular involvement was relapsing iridocyclitis, being observed in 57. 7% and the disease led to a bilateral loss of vision in 38. 4% 5) Single or combined therapy including corticosteroids and antimicrobials gave transient conservative effects and was of no value to prevent recurrent attacks.
Adrenal Cortex Hormones ; Behcet Syndrome* ; Busan ; Dermatology ; Erythema Multiforme ; Erythema Nodosum ; Female ; Humans ; Incidence ; Iridocyclitis ; Male ; Pyoderma ; Stomatitis, Aphthous ; Ulcer

A case of foreign body (a black rubber string of 60cm in length used for masturbation) in the bladder was presented in a 17 years old Korean boy and reported with review of literature.
Adolescent ; Foreign Bodies* ; Humans ; Male ; Rubber ; Urinary Bladder*

A case of 28 year-old female having vesico-sigmoido-ileal fistula associated with large bladder stone due to long-standing foreign body was presented with review of literatures.
Adult ; Female ; Fistula* ; Foreign Bodies ; Humans ; Urinary Bladder Calculi

Intraosseous Neurilemmomas are very rare tumor and most of them are arose in the mandibular bone. A case report is made on the intraosseous neurilemmoma in the distal shaft of tibia which belong very rarely seen in the area of bone. The case was a 23 year old male who had multicystic lesion on the distal shaft of right tibia with marginal this sclerotic change on the radiological examination. The lesion of intraosseous neurilemmoma was confirmed by the microscopic examination after surgical treatment of curettage and bone graft. Also a review of literature on the neurilemmoma was made and reported.
Curettage ; Humans ; Male ; Neurilemmoma ; Tibia ; Transplants

BACKGROUND: In patients with mitral stenosis, the degree of pulmonary hypertension is expected to be related to the severity of mitral valve obstruction. However, some patients with severe mitral stenosis do not develop reactive pulmonary hypertension. MATERIALS AND METHODS: We evaluated 34 patients with symptomatic mitral stenosis undergoing percutaneous mitral valvuloplasty by clinical, echocardiographic, and invasive hemodynamic(cardiac cathrterization) data. Prevalvuloplasty data were available in 34 subjects[mean age 38+/-9 year ; women 74% ; NYHA class 1 (6 patients), class 2 (17 patients), class 3 (7 patients), class 4 (4 patients) ; in electrocardiography, NSR(23 patients), Atrial fibrillation(11 patients)]. RESULTS: 1) The pulmonary vascular bed gradient was significantly correlated with pulmonary vascular resistance(r=0.91), mean pulmonary artery pressure(r=0.82), transmitral mean pressure gradient(r=0.64) and mitral valve area(r=-0.48). The pulmonary vascular resistance was significantly correlated with mena pulmonary artery pressure(r=0.77), transmiral mean pressure gradient(r=0.61) and mitral valve area(r=-0.54), NYHA functional classification(r=0.36). However, the pulmonary vascular bed gradient and pulmonary vascular resistance was not significantly correlated with age, sex, cardiac output, the severity of mitral regurgitation and mean left atrial pressure. 2) The mean pulmonary artery pressure was significantly correlated with mean left atrial pressure(r=0.80), transmitral mean pressure gradient(r=0.72) and mitral valve area(r=-0.47). 3) When patients were divided into those with a pulmonary vascular bed gradient > 12mmHg and Atrial Pressure ; Cardiac Output ; Echocardiography ; Electrocardiography ; Female ; Heart Diseases ; Humans ; Hypertension, Pulmonary* ; Mitral Valve ; Mitral Valve Insufficiency ; Mitral Valve Stenosis* ; Pulmonary Artery ; Vascular Resistance

BACKGROUND: Emergence agitation (EA) frequently occurs after general anesthesia in children. This multicenter study was investigated to determine incidence and risk factors of EA after general anesthesia in children. METHODS: This prospective study evaluated 816 pediatric patients receiving elective surgery under general anesthesia at 10 university hospitals. Emotional and behavioral status of the patients upon emergence from anesthesia was assessed by Aono's four point scale. Those with an Aono's four point scale of 3 or 4 were considered to be affected by EA. Patient physical, anesthetic, and surgical variables were analyzed to find the risk factors of EA. RESULTS: One-hundred-fifty-two children (18.6%) developed EA. No relationships between the incidence of EA and age, sex, ASA physical status, premedicants, anesthetic induction agents, anesthetic maintenance methods, or postoperative analgesia were found. A multivariate analysis identified preanesthetic emotional status (OR = 1.774, P < 0.001), perioperative airway complication (OR = 1.867, P < 0.007) and rhinolaryngologic surgery (OR = 1.597, P < 0.017) as risk factors of EA. CONCLUSIONS: Preanesthetic emotional status, perioperative airway complication and rhinolaryngologic surgery were risk factors of EA after general anesthesia in children.
Analgesia ; Anesthesia ; Anesthesia, General ; Anesthetics ; Child ; Dihydroergotamine ; Hospitals, University ; Humans ; Incidence ; Multivariate Analysis ; Prospective Studies ; Risk Factors

A 59-year-old female patient with rheumatoid arthritis showed hypokalemic metabolic alkalosis, normotensive hyperreninemic hyperaldosteronism and high urinary prostaglandin level. She was thought to have Bartter's syndrome. But, her kidney biopsy specimen showed chronic interstitial nephritis. She have used acetaminophen containing analgesics for recent three years. So we thought her disease was caused by drug. But, in this case, clinical manifestations are correspond with Bartter's syndrome and we have witnessed a successful respond to kalium replacement, angiotensin converting enzyme inhibitor, prostaglandin inhibitor and spironolactone administration.
Acetaminophen ; Alkalosis ; Analgesics ; Arthritis, Rheumatoid* ; Bartter Syndrome ; Biopsy ; Female ; Glycogen Storage Disease Type VI ; Humans ; Hyperaldosteronism ; Kidney ; Middle Aged ; Nephritis, Interstitial* ; Peptidyl-Dipeptidase A ; Prostaglandin Antagonists ; Spironolactone