In September 1998, a case of nosocomial cutaneous myiasis caused by Lucilia sericata (Meigen, 1826) in a 77-year-old male was found. The patient had been receiving partial maxillectomy due to the presence of malignant tumor on premaxilla. This is the first verified case involving Lucilia sericata in Taegu, Korea. In the present paper, the salient morphological features of the third instar larvae involved have been studied.
Aged ; Animals ; Cross Infection/*parasitology ; Diptera/ultrastructure ; Face ; Human ; Larva/ultrastructure ; Male ; Microscopy, Electron, Scanning ; Myiasis/*parasitology ; Skin Diseases, Parasitic/*parasitology ; Surgical Wound Infection/*parasitology

BACKGROUND: As modern epidemiologic studies began to identify obesity as a risk factor for cardiovascular disease, diabetes, hypertension, and cancer, measuring the degree of excess body fat is important on epidemiologic surveys. The evaluation of obesity level in epidemiologic surveys has been mostly done indirectly by measuring patient's height and weight. But, the anthropometry could not be done to respondents of recalling past anthropometric values or to proxy respondents. This study was attempted to elucidate usefulness of a somatotype drawing as a measuring instrument of obesity level in epidemiologic surveys in Korea. METHOD: The inclusion criteria of subjects were (1) members of the Seoul Cohort Study, who were recruited by self-administered structured questionnaire survey through mailing to the healthy men between the ages of 40 and 59 years through the program of a biennial health checkup offered by the Korean Medical Insurance Corporation (KMIC), and (2) volunteers for cancer screening program offered by KMIC. For assessing usefulness of the instrument, measurement of status/weight and self-administered questionnaire survey were done separately through the program of a biennial health checkup and of cancer screening. RESULTS: The data were collected from 138 subjects, whose Body Mass Index (kg/M2) was 23.58+/-1.46 (mean+/-SD). When the validity was measured through correlation with BMI, Spearman's correlation coefficient (rs) was 0.72 (p<0.05), that remained statistically significant after adjusting age, education level, and monthly income and occupation. And, the grades of somatotypo drawing were grouped as 1-3, 4-6, 7-8 by ANOVA and Tukey test. CONCLUSIONS: Instrument using somatotype drawing is applicable to screen degree of body fat in self-administered questionnaire surveys in Korea.
Adipose Tissue ; Anthropometry ; Body Mass Index ; Cardiovascular Diseases ; Cohort Studies ; Surveys and Questionnaires ; Early Detection of Cancer ; Education ; Epidemiologic Studies ; Humans ; Hypertension ; Insurance ; Korea* ; Male ; Obesity* ; Occupations ; Postal Service ; Proxy ; Risk Factors ; Seoul ; Somatotypes* ; Volunteers

A highly specific antigenic protein of 31 kDa from plerocercoid of Spirometra mansoni (sparganum) was obtained by gelatin affinity and Mono Q anion-exchange column chromatography. The purified 31 kDa protein was subjected to N-glycan enzymatic digestion for structural analysis. The relative electrophoretic mobility was analyzed by SDS-PAGE, before and after digestion. On SDS-PAGE after enzymatic digestion, the 31 kDa protein showed a molecular shift of approximately 2 kDa, which indicated the possession of complex N-linked oligosaccharides (N-glycosidase F sensitive) but not of high-mannose oligosaccharides (endo-beta-N-acetylglucosaminidase H, non-sensitive). Chemically periodated 31 kDa protein showed statistically non-significant changes with human sparganosis sera by enzyme linked immunosorbent assay (ELISA). Therefore, the dominant epitopes of the 31 kDa molecule in human sparganosis were found to be mainly polypeptide, while N-glycans of the antigenic molecule in sparganum was minimal in anti-carbohydrate antibody production.
Animals ; Antigens, Helminth/*analysis/chemistry/immunology/metabolism ; Carbohydrates/analysis/immunology ; Chromatography, Affinity ; Chromatography, Ion Exchange ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Epitopes/analysis/immunology ; Glucosaminidase/metabolism ; Human ; Peptide-N4- (N-acetyl-beta-glucosaminyl) Asparagine Amidase/metabolism ; Periodic Acid/chemistry ; Sparganosis/*parasitology ; Sparganum/immunology/metabolism ; Spirometra/immunology/*metabolism ; Support, Non-U.S. Gov't

The aim of this study was to assess the degree of association between individual stress and the amount of smoking among male senior students of a medical college. The questionnaire survey was conducted twice for collecting the data on stress level in terms of BEPSl score, smoking amounts, alcohol intake, and residence type in 1992 and 1993. Among the 223 responders, 39.9% were smokers. In the smokers, the association between stress level and smoking amount was significant after controlling for alcohol intake and residence type (P < 0.l). Especially in the group of living without family, the association was more significant (p=0.06). Therefore, it is recommendable that the stress management program is called upon for the student smokers to reduce smoking amount.
Humans ; Male ; Surveys and Questionnaires ; Smoke* ; Smoking*

No abstract available in English.
Fracture Fixation, Intramedullary

PURPOSE: The purpose of this seroepidmiologic study was to examine the immunization and infection history of rubella, positivity of rubella specific antibody, seroconversion rate of two rubella vaccines and to develop an adequate immunization program of rubella. Research Methods : Subjects of the study were 2.071 students of 8 priamary schools in Gyenggi-Do. Questionnaire and blood sampling were done. Test method of Rubella specific antibody was ELISA (Abbott IMx autoanalyzer). The anayltic methods for the study were chi-square-test, t-test and ANOVA. RESULTS: The results of the study were as follows : (1)The number of subjects who had infection history of rubella were only 28 students(1.5%). (2)The immunization rate of rubella was the highest in 6 year-old group(65%), it decrease as subjects grow older. (3)The positivity of rubella antibody was 76. 6%, it is the highest in 6 year old group and the lowest in 7 year-old group and it increase again as subjects grow older. (4)Average antibody titer was 53.3 IU(SD 79.2), the trend of antibody titer by age was similar to that of positivity. (5)The seroconversion rates of both vaccines, vaccine A,vaccine B, were 99.5% and 99.6%, the ratio of increase of antibody titer after immunization was higer than 400. it means that both vaccines are very efficacious. CONCLUSION: Results of the study suggest that it is necessary to increase the coverage of rubella immunization, and further studies are necessary to get more information for rubella.
Child ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunization ; Immunization Programs ; Rubella* ; Seroepidemiologic Studies* ; Vaccines ; Surveys and Questionnaires

Choriocarcinoma associated with a normal pregnancy is rare. Futhermore, choriocarcinoma coexistent with a viable pregnancy is even rarer and associated with a greater risk of hepatic and cerebral involvement. So timely diagnosis of the disease is important for successful treatment and aggressive diagnostic procedures may therefore warranted. The patient should be treated with primary intensive combination chemotherapy(EMA-CO) and the selective use of irradiation and surgical therapy. We experienced a case of metastatic choriocarcinoma of lung and kidney following preterm delivery at 34th week of pregnancy and so present it with brief review of literature.
Choriocarcinoma* ; Diagnosis ; Female ; Humans ; Kidney ; Lung ; Pregnancy ; Pregnancy*

Teratomas of the fallopian tube are extremely rare, and only about 50 cases have reported in the world literature. Most cases of mature cystic tubal teratoma are asymptomatic and are discovered as an incidental finding on physical or radiologic examination, or at the time of laparatomy. We report a case of mature cystic teratoma of the right fallopian tube which was discovered during pelvic ultrasonogram for antenatal care in a 28 year old woman. Right salpingectomy was performed during cesarean section for cephalo-pelvic distortion at IUP 39 weeks. Gross examination of the right fallopian tube reveals a distended fallopian tube, measuring 8cm in length and 2cm in diameter. On section, it is filled with several small pedunculated nodules and cysts containing sebaceous materials. Microscopically the tumor was seen in continuity with the lining epithelium of mucosal folds. The majority of the tumor was composed of well differentiated mature elements of three germ layers with skin and skin appendages, mature brain tissue, bone, breast tissue, intestinal mucosa and bronchial epithelium.
Female ; Humans ; Cysts

The cysteine proteases of Paragonimus westermani metacercariae are involved in metacercarial excystment, host immune modulation, and possibly in tissue penetration. In order to clarify the origin of the enzymes, 28 and 27 kDa cysteine proteases in metacercarial excretory-secretory products were purified through the FPLC system using Mono Q column chromatography. The polyclonal antibodies to the enzymes were produced in BALB/c mice. Immunolocalization studies revealed that both cysteine proteases were distributed at the linings of excretory bladder and excretory concretions of the metacercariae. It was suggested that the excretory epithelium of P. westermani undertake the secretory function of metacercarial cysteine proteases, in addition to its role as a route for eliminating waste products.
Animals ; Chromatography, Liquid ; Computational Biology ; Cysteine Endopeptidases/analysis/isolation & purification/*physiology ; Immunohistochemistry ; Mice ; Mice, Inbred BALB C ; Paragonimus/anatomy & histology/*enzymology ; Support, Non-U.S. Gov't

OBJECTIVES: 'High-normal blood pressure' is a factor influencing decision to initiate targeted intensive intervention strategy in westernized populations. JNC-VI offered the vigorous lifestyle modification for persons with 'high-normal blood pressure', who could be early detected. As a hypertension seems to be the result of multiple genetic factors operating in concert with associated environmental factors, it will be necessary to identify the high-normal blood pressure as a risk factor of hypertension for applying primary prevention strategy in Korean people. METHODS: Although cohort study design might be adequate to recruit incidence cases, to keep time sequence of events, and to prevent information bias, nested case-control study was chosen for avoiding measurement errors because hypertension is a benign disease. Source population was the 'Seoul Cohort' participants and follow-up was done by using Korea Medical Insurance Corporation's database on the utilization of health services from 1Jan93 to 30Jun97. Incidence cases were ascertained through the chart review, telephone contacts, and direct blood pressure measurements. Controls included the pairing of 4 individuals to each case on the basis of age. RESULTS: As 75 % of 247 incident cases had high-normal blood pressure, the crude odds ratio for hypertension was 2.04 (95% CI 1.47-2.83). Another statistically significant risk factors of hypertension were body mass index, dietary fiber, alcohol consumption, weekly activity and history of quitting smoking. The multivariate odds ratio of high-normal blood pressure adjusted for all risk factors was 1.84 (95 % CI 1.31-2.56). Among high-normal blood pressure group, body mass index, weekly ethanol amounts, weekly physical activity, and dietary fiber except history of quitting smoking were still risk factors of hypertension. CONCLUSION: 'High-normal blood pressure' is a risk factor for hypertension in Korean middle-aged men, which represents that the vigorous lifestyle modification for persons with 'high-normal blood pressure' is need.
Alcohol Drinking ; Bias (Epidemiology) ; Blood Pressure* ; Body Mass Index ; Case-Control Studies* ; Cohort Studies ; Dietary Fiber ; Ethanol ; Follow-Up Studies ; Health Services ; Humans ; Hypertension* ; Incidence ; Insurance ; Korea ; Life Style ; Male ; Motor Activity ; Odds Ratio ; Primary Prevention ; Risk Factors* ; Smoke ; Smoking ; Telephone