1.Two Cases of Unilateral Nevoid Telangiectasia.
Annals of Dermatology 2000;12(3):185-188
Unilateral nevoid telangiectasia(UNT) is a rare disorder and is characterized by superficial telangiectatic lesions distributed along the dermatomes unilaterally and usually on the upper part of the body. It has been said to be related to increased estrogen receptors in the involved skin. The lesions may be congenital or acquired.Acquired cases are typically associated with physiologic conditions such as pregnancy, puberty, hormonal therapy or cirrhosis, but the condition is also described in alcoholism without cirrhosis, carcinoma metastatic to the liver, and in hepatitis C. We present two cases of UNT in a 26-year-old man with heavy alcoholism and in a puberta1 16-year-old girl.
Adolescent
;
Adult
;
Alcoholism
;
Female
;
Fibrosis
;
Hepatitis C
;
Humans
;
Liver
;
Pregnancy
;
Puberty
;
Receptors, Estrogen
;
Skin
;
Telangiectasis*
2.Enzymatic N-glycan analysis of 31 kDa molecule in plerocercoid of Spirometra mansoni (sparganum) and its antigenicity after chemical oxidation.
Young Bae CHUNG ; Yoon KONG ; Hyun Jong YANG
The Korean Journal of Parasitology 2004;42(2):57-60
A highly specific antigenic protein of 31 kDa from plerocercoid of Spirometra mansoni (sparganum) was obtained by gelatin affinity and Mono Q anion-exchange column chromatography. The purified 31 kDa protein was subjected to N-glycan enzymatic digestion for structural analysis. The relative electrophoretic mobility was analyzed by SDS-PAGE, before and after digestion. On SDS-PAGE after enzymatic digestion, the 31 kDa protein showed a molecular shift of approximately 2 kDa, which indicated the possession of complex N-linked oligosaccharides (N-glycosidase F sensitive) but not of high-mannose oligosaccharides (endo-beta-N-acetylglucosaminidase H, non-sensitive). Chemically periodated 31 kDa protein showed statistically non-significant changes with human sparganosis sera by enzyme linked immunosorbent assay (ELISA). Therefore, the dominant epitopes of the 31 kDa molecule in human sparganosis were found to be mainly polypeptide, while N-glycans of the antigenic molecule in sparganum was minimal in anti-carbohydrate antibody production.
Animals
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Antigens, Helminth/*analysis/chemistry/immunology/metabolism
;
Carbohydrates/analysis/immunology
;
Chromatography, Affinity
;
Chromatography, Ion Exchange
;
Electrophoresis, Polyacrylamide Gel
;
Enzyme-Linked Immunosorbent Assay
;
Epitopes/analysis/immunology
;
Glucosaminidase/metabolism
;
Human
;
Peptide-N4- (N-acetyl-beta-glucosaminyl) Asparagine Amidase/metabolism
;
Periodic Acid/chemistry
;
Sparganosis/*parasitology
;
Sparganum/immunology/metabolism
;
Spirometra/immunology/*metabolism
;
Support, Non-U.S. Gov't
3.Treatment of Gonorrhoea.
Joong Hwan KIM ; Hong Yoon YANG ; Young Tae KIM
Annals of Dermatology 1989;1(2):69-72
Because of increasing resistance of circulating N. gonorrhoeae and frequent failures in the treatment of gonorrhoea, intensive work on gonorrhoea has become of paramount importance. During January 1980-April 1984, at the Choong-Ku VD Clinic in Seoul, 3,340 male patients with uncomplicated gonococcal urethritis were treated with various treatment regimens. Diagnosis of gonorrhoea and declaration of a treatment failure were made on the basis of positive urethral culture. In 1984, the prevalence of Penicillinase Producing N. gonorrhoeae (PPNG) was about 30%, The pretreatment minimun inhibitory concentration of various antibiotics were quite high. Even for non-PPNG urethritis standard penicillin regimens gave unsatisfactory results. For PPNG urethritis, only spectinomycin, cefoperazone and cefotaxim-probenecid regimens gave satisfactory results. No spectmomycin resistant strain of N. gonorrhoeae has been found since 1982 at the Choong-Ku VD Clinic. As an agent of single drug therapy, spectinomycin seems to be one of the most cost effective drugs in the treatment of uncomplicated gonorrhoea in men.
Anti-Bacterial Agents
;
Cefoperazone
;
Diagnosis
;
Drug Therapy
;
Humans
;
Male
;
Penicillinase
;
Penicillins
;
Prevalence
;
Seoul
;
Spectinomycin
;
Treatment Failure
;
Urethritis
4.A case of renal transplantation of anti-neutrophil cytoplasmic autoantibody(ANCA)-related repidly progressive glomerulonephritis.
Chul Woo YANG ; Suk Joo AHN ; Suk Young KIM ; Yoon Sik CHANG ; Young Suk YOON ; Byung Kee BANG
Korean Journal of Nephrology 1993;12(1):91-94
No abstract available.
Biopsy*
;
Cytoplasm*
;
Follow-Up Studies*
;
Glomerulonephritis*
;
Kidney Transplantation*
5.Balanitis Circumscripta Plasmacellularis.
Young Suck RO ; Pyung Won PARK ; Chan Kum PARK ; Hong Yoon YANG ; Young Tae KIM
Annals of Dermatology 1991;3(2):158-163
A 79-year-old man with balanitis circumscripta plasmacellularis(BCP), presenting as an erythematous constricting band of the inner surface of the prepuce encircling the penile shaft is described. The biopsy specimen of the lesion showed, in addition to the typical histologic findings of BCP, increased fibrosis and decreased amount of elastic fibers which correlate well with our clinical observations. Electron microscopic examination revelaed no viral particles or elastic fibers. Immunohistologically, IgG was found to be the major immunoglobulin class in the plasma cellular inf iltrate.
Aged
;
Balanitis*
;
Biopsy
;
Elastic Tissue
;
Fibrosis
;
Humans
;
Immunoglobulin G
;
Immunoglobulins
;
Male
;
Plasma
;
Virion
6.A clinical study of laryngeal premalignant lesions.
Ki Hwan HONG ; Seong Woan KIM ; Jin Young YANG ; Young Chan LEE ; Yong Joo YOON
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):89-99
No abstract available.
7.Portal and mesenteric vein thrombosis in a patient with nephrotic syndrome.
Wan Uk KIM ; Young Shin SHIN ; Chul Woo YANG ; Youg Soo KIM ; Suk Young KIM ; Yoon Sik CHANG ; Young Suk YOON ; Byung Kee BANG ; Hyun Kwon HA
Korean Journal of Nephrology 1993;12(4):682-685
No abstract available.
Humans
;
Mesenteric Veins*
;
Nephrotic Syndrome*
;
Thrombosis*
8.Glomangiomyoma on the Face.
Tae Ho YANG ; Youn Soo KIM ; Mi Kyeong KIM ; Tae Young YOON
Annals of Dermatology 2002;14(1):31-34
We report a rare case of glomangiomyoma in a 25-year-old man who had an asymptomatic, 1.5 × 1.5cm sized, round, skin-colored, soft mass on the right cheek. Histopathologically, the lesion was consistent with glomangiomyoma which showed irregularly dilated vessels lined by endothelial cells and several outer layers of glomus cells, and smooth muscles distributed within the tumor. The tumor cells were characterized immunohistochemically by the presence of smooth muscle actin, muscle specific actin, and vimentin. To our knowledge, this is the first case report of glomangiomyoma on the facial location in the Korean literature.
Actins
;
Adult
;
Cheek
;
Endothelial Cells
;
Glomus Tumor
;
Humans
;
Muscle, Smooth
;
Vimentin
9.A case of prenatally detected, repetitive familial 4/22 translocation of maternal origin.
Young Ho YANG ; Yoon Tae LEE ; Se Kwang KIM ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):2808-2812
No abstract available.
10.Excretory bladder: the source of cysteine proteases in Paragonimus westermani metacercariae.
Hyun Jong YANG ; Young Bae CHUNG ; Shin Yong KANG ; Yoon KONG ; Seung Yull CHO
The Korean Journal of Parasitology 2002;40(2):89-92
The cysteine proteases of Paragonimus westermani metacercariae are involved in metacercarial excystment, host immune modulation, and possibly in tissue penetration. In order to clarify the origin of the enzymes, 28 and 27 kDa cysteine proteases in metacercarial excretory-secretory products were purified through the FPLC system using Mono Q column chromatography. The polyclonal antibodies to the enzymes were produced in BALB/c mice. Immunolocalization studies revealed that both cysteine proteases were distributed at the linings of excretory bladder and excretory concretions of the metacercariae. It was suggested that the excretory epithelium of P. westermani undertake the secretory function of metacercarial cysteine proteases, in addition to its role as a route for eliminating waste products.
Animals
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Chromatography, Liquid
;
Computational Biology
;
Cysteine Endopeptidases/analysis/isolation & purification/*physiology
;
Immunohistochemistry
;
Mice
;
Mice, Inbred BALB C
;
Paragonimus/anatomy & histology/*enzymology
;
Support, Non-U.S. Gov't