1.The toxic effects of cryoprotectants on the mouse embryo.
Chung Hoon KIM ; Shin Yong MOON ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1400-1409
No abstract available.
Animals
;
Embryonic Structures*
;
Mice*
2.Patients' Satisfaction after Reverse Total Shoulder Arthroplasty Is Affected by Preoperative Functional Status.
Jong Pil YOON ; Dong Hyun KIM ; Seok Won CHUNG
Clinics in Shoulder and Elbow 2016;19(3):119-124
BACKGROUND: The purpose of this study is to evaluate the functional outcomes of reverse total shoulder arthroplasty (RTSA) and to assess factors affecting the patients' subjective satisfaction after RTSA. METHODS: Forty-three patients (mean age, 75.0 ± 5.2 years) who underwent RTSA for cuff tear arthropathy or irreparable cuff tears with preoperative magnetic resonance imaging and pre- and postoperative radiographs at 1 year, and whose various functional outcomes including pain visual analogue scale (VAS), simple shoulder test, Constant score, American Shoulder and Elbow Surgeons score, and active range of motion were evaluated preoperatively and at the last follow-up (>12 months) were enrolled. The outcome parameter was set as a satisfaction scale. Various clinical and radiographic factors were analyzed, and their correlations with postoperative satisfaction were evaluated. RESULTS: All functional scores, VAS pain score, and active forward flexion showed significant improvement after surgery (all p<0.001). Twenty-nine patients were satisfied with the results and 14 were dissatisfied. The presence of pseudoparalysis (p=0.028) and worse preoperative function (all p<0.05) were related with higher satisfaction. Any radiologic parameters did not affect patients' postoperative satisfaction. CONCLUSIONS: All patients showed a good functional outcome after RTSA, however the patients' subjective postoperative satisfaction was affected by preoperative functional status (higher satisfaction in poor preoperative function), not by radiological findings.
Arthroplasty*
;
Elbow
;
Follow-Up Studies
;
Humans
;
Magnetic Resonance Imaging
;
Range of Motion, Articular
;
Shoulder*
;
Surgeons
;
Tears
3.Treatment of torn discoid meniscus in children
Hong Chul LIM ; Seok Hyun LEE ; Yoon Sung CHUNG
The Journal of the Korean Orthopaedic Association 1995;30(1):97-103
In children, snapping knee syndrome and joint pain with the loss of physiological hyperextension strongly suggests a diagnosis of a torn discoid meniscus. We performed arthroscopic meniscectomy to treat torn discoid lateral meniscus on 19 knees and open meniscectomy on 9 knees of 26 children(average age: 10.9 yrs) from September, 1983 to October, 1993 at Guro hospital. According to Ikeuchi's grading system', excellent results were obtained in 14, good in 11, fair in 2 knees and poor in 1 knee which was associated with osteochondritis dissecans. The knees treated by partial meniscectomy showed less Fairbank's radiologic changes than those by total meniscectomy during the average follow-up 4.2 years(minimum 1 year, maximum 7 year 11 months).
Arthralgia
;
Child
;
Diagnosis
;
Follow-Up Studies
;
Humans
;
Knee
;
Menisci, Tibial
;
Osteochondritis Dissecans
4.Hrombosed Aortic Dissections and Aortic Aneurysms: MRI Findings and Differential Diagnosis.
Jin Wook CHUNG ; Jae Hyung PARK ; Man Chung HAN ; Gi Seok HAN ; Yong Kyu YOON
Journal of the Korean Radiological Society 1994;30(5):853-858
PURPOSE: MRI is known to be an effective imaging modality of the aorta and its role is steadily increasing in the evaluation of acquired aortic diseases including aortic dissections and aortic aneurysms. However, differentiation of the aortic dissections with thrombosed false lumen from the aortic aneurysm with mural thrombus in MRI has not been easy. Therefore, the authors tried to find the characteristic MR featrses which would to differentiate the two diseases. MATERIALS AND METHODS: MR images of 6 patients with thrombosed aortic dissection and 7 patients with thrombosed aortic aneurysms were reviewed retrospectively and compared in regand to shape and extent of thrombus, dimension of aorta, and luminal flow signal. RESULTS: Thrombosed aortic dissections showed sharply demarcated crescent shaped aortic wall thickening of even thickness involving long segment of the aorta, whereas thrombosed aortic aneurysms showed irregular aortic wall thickening of uneven thickness localized in the short dilated segment of the aorta. Characteristically aortic aneurysm with mural thrombus showed eccentric intraluminal slow flow signal. In contrast to the signal void of the true lumen in aortic dissections, the residual lumen of the aortic aneurysm with mural thrombus revealed intraluminal signal due to slow flow. CONCLUSION: Familiarity to these MRI findings of thrombosed aortic dissections and aortic aneurysms may lead to the accurate differential diagnosis in majority of cases.
Aorta
;
Aortic Aneurysm*
;
Aortic Diseases
;
Diagnosis, Differential*
;
Humans
;
Magnetic Resonance Imaging*
;
Phenobarbital
;
Recognition (Psychology)
;
Retrospective Studies
;
Thrombosis
5.Inhibition of Contact Hypersensitivity by PUVA Treatment.
Sung Ho BAE ; Yun Shin CHUNG ; Seok Don PARK ; Hyang Suk YOON ; Hun Taeg CHUNG
Annals of Dermatology 1990;2(1):1-8
Normal C3WHeN strain mice exposed to topical 8inethoxypsomlen plus long wave ultraviolet (PUVA) showed a reduction in contact hypersensitivity, (CH) which was localized to the skin in the area of PUVA treatment (local suppression), whereas systemic PUVA treatment caused diffuse suppression of CH reaction, regardless of the application site of 2,4-dinitro-1-fluorobenzene (DNFB). There seem to be two different mechanisms responsible for CH reduction by PUVA. Local suppression by topical PUVA treatment was thought to be a result of blocking the afferent phase of immune response, it was associated with a lack of CH effector cells in the peripheral lymph nodes and could not be reversed by indomethacin treatment. Diffuse suppression induced by systemic PUVA treatment seemed to be associated with blocking of egress of effector cells from the regional lymph nodes, this depressed CH response was prevented when indomethacin was administered before PUVA treatment.
Animals
;
Dermatitis, Contact*
;
Indomethacin
;
Lymph Nodes
;
Mice
;
Skin
6.Kasai Operation for Extrahepatic Biliary Atresia - Survival and Prognostic Factors.
Chan Seok YOON ; Seok Joo HAN ; Young Nyun PARK ; Ki Sup CHUNG ; Jung tak OH ; Seung Hoon CHOI
Journal of the Korean Association of Pediatric Surgeons 2006;12(2):202-212
The prognostic factors for extrahepatic biliary atresia (EHBA) after Kasai portoenterostomy include the patient's age at portoenterostomy (age), size of bile duct in theporta hepatis (size), clearance of jaundice after operation (clearance) and the surgeon's experience. The aim of this study is to examine the most significant prognostic factor of EHBA after Kasai portoenterostomy. This retrospective study was done in 51 cases of EHBA that received Kasai portoenterostomy by one pediatric surgeon. For the statistical analysis, Kaplan-Meier method, Logrank test and Cox regression test were used. A p value of less than 0.05 was considered to be significant. Fifteen patients were regarded as dead in this study, including nine cases of liver transplantation. There was no significant difference of survival to age. The age is also not a significant risk factor for survival in this study (Cox Regression test; p = 0.63). There was no significant difference in survival in relation to the size of bile duct. However, bile duct size was a significant risk factor for survival (Cox Regression test; p = 0.002). There was a significant difference in relation to survival and clearance (Kaplan-Meier method; p = 0.02). The clearing was also a significant risk factor for survival (Cox Regression test; p = 0.001). The clearance of jaundice is the most significant prognostic factor of EHBA after Kasai portoenterostomy.
Bile Ducts
;
Biliary Atresia*
;
Humans
;
Jaundice
;
Kaplan-Meier Estimate
;
Liver Transplantation
;
Prognosis
;
Retrospective Studies
;
Risk Factors
7.Morbidity pattern of residents in urban poor area by health screening.
Chang Yoon KIM ; Jun SAKONG ; Seok Beom KIM ; Pock Soo KANG ; Jong Hak CHUNG
Yeungnam University Journal of Medicine 1991;8(2):150-157
The purpose of this study was to assess the morbidity pattern of urban residents in the poor area by health screening for the community diagnosis. The items of health screening were history taking and physical examination by medical doctor and hearing test, check blood pressure, test for hematocrit, liver function (sGOT, sGPT), urine sugar and protein, and chest X-ray. The examinee in health screening were 437 persons and they occupied 16.9% of total residents in the poor area. Male examinee were 129 persons (9.9% of total residents) and female examinee were 308 persons (23.9% of total residents). Age group of above sixty years old, 42.0% of total residents in the poor area were participated, but only 5.9% were participated in age group of 10 to 19 years old. Among the 437 examinee, 191 persons (43.7%) had one or more abnormal findings in health screening. In male 38.7% had abnormal findings, and somewhat lower than that of female (45.8%). Age group of above sixty years had most high rate of abnormal findings (69.8%), in contrast to age group of 10 to 19 years old (10.9%). Diseases of the digestive system was the most common and which occupies 23.7% of total abnormal findings. And diseases of the circulatory system occupied 19.7%. Low hematocrit (14.6% of total participants of 437 persons) occupies the most common abnormal findings for screening test (hematocrit, blood pressure, hearing test, sGOT/sGPT, urine protein and urine sugar, chest X-ray) and high blood pressure (10.1%) occupied second, third; hearing impairment (5.5%), fourth; abnormal liver function (4.1%), fifth; sugar in urine (2.3%), sixth; protein in urine (1.4%) and lastly abnormal chest X-ray (0.9%). The positive rate of abnormal findings in health screening was very high compared with morbidity rate by health interview. It is supposed that some portion of this high rate is by selection bias in examinee in health screening specially high participating rate in older age, and the other portion is due to the low socioeconomic status and bad environment of the residents of the poor area. These findings will be good information for the research and development of health care system in the urban poor area.
Blood Pressure
;
Delivery of Health Care
;
Diagnosis
;
Digestive System
;
Female
;
Hearing Loss
;
Hearing Tests
;
Hematocrit
;
Humans
;
Hypertension
;
Liver
;
Male
;
Mass Screening*
;
Physical Examination
;
Selection Bias
;
Social Class
;
Thorax
8.Comparison of Clinical Outcomes according to the Catheters undergoing Intrauterine Insemination.
Hee Dong CHAE ; Eun Hee KANG ; Chung Hoon KIM ; Byung Moon KANG ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 2000;43(2):254-259
OBJECTIVE: To compare the clinical outcomes of intrauterine insemination (IUI) according to the catheter used. MATERIALS AND METHOD: From March 1998 to September 1998, total 95 infertile patients were included in this study. Patients were randomly allocated to TomCat group (n = 39) and Mackler group (n = 56) according to the catheter for insemination. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone agonist (GnRH-a) was used in all patients. Statistical analysis was performed using Student's t-test, Fisher's exact test, and x2 test as appropriate. Statistical significance was defined as p < 0.05. RESULTS: The total dose and duration of exogeneous gonadotropin required were similar between the two groups. There were also no significant differences in serum estradiol (E2) level, endometrial thickness and texture on the day of hCG administration between the two groups. However, the percentage of uterine souding due to failure of initial approach was significantly higher in TomCat group compared to Mackler group (23.1% vs. 0%, p < 0.01). The percentage of bleeding after IUI in TomCat group seemed to be higher than that in Mackler group (15.4% vs. 3.6%, p = 0.06), although there was no statistically significant difference between the two groups. There was also no significant difference in the clinical pregnancy rate per patient between the two groups. CONCLUSION: These results suggested that using Mackler catheter might be effective for IUI, especially for the patients with cervical factor infertility.
Catheters*
;
Estradiol
;
Gonadotropin-Releasing Hormone
;
Gonadotropins
;
Hemorrhage
;
Humans
;
Infertility
;
Insemination*
;
Pregnancy Rate
9.A Case of Aberrant Lacrimal Gland.
Journal of the Korean Ophthalmological Society 1981;22(2):389-393
Ectopic or Aberrant lacrimal gland, which has been observed in the eye and in various sites on the ocular adnexa is an unusual congenital and developmental abnormality. The authors have recently experienced one case of Aberrant lacrimal gland in the upper and lateral quadrant of the bulbar conjunctiva involving the cornea on right eye in a 10 year old Korean girl. It was reviewed clinically with the literature.
Child
;
Conjunctiva
;
Cornea
;
Female
;
Humans
;
Lacrimal Apparatus*
10.A study on in vitro developmental promoting effect of pronucleate I-cell mouse embryos by human amniotic fluid.
Ku Min CHUNG ; Shin Yong MOON ; Jin Yong LEE ; Yoon Seok CHANG
Korean Journal of Fertility and Sterility 1991;18(2):173-179
No abstract available.
Amniotic Fluid*
;
Animals
;
Embryonic Structures*
;
Female
;
Humans*
;
Mice*