1.Anaerobic bacteria isolated from the clinical specimens during the period of 1983 to 1992.
Ahn Na LEE ; Young Sook KANG ; Kyung Won LEE ; Yoon Seob JUNG ; Kyung Soon SONG
Korean Journal of Infectious Diseases 1993;25(1):9-17
No abstract available.
Bacteria, Anaerobic*
2.A case of non-gestational, primary choriocarcinoma of ovary.
Sang NA ; Jae Gon CHO ; Sang Jin KIM ; Kyu Seob LEE ; Man Soo YOON ; Won Whe KIM
Korean Journal of Obstetrics and Gynecology 1993;36(7):2813-2822
No abstract available.
Choriocarcinoma*
;
Female
;
Ovary*
;
Pregnancy
3.The change of brain temperature during forebrain ischemia in rat.
Yoon Seob NA ; Jae Young KWON ; Hae Kyu KIM ; Soung Wan BAIK ; Inn Se KIM ; Kyoo Sub CHUNG
The Korean Journal of Critical Care Medicine 1992;7(1):35-40
No abstract available.
Animals
;
Brain*
;
Ischemia*
;
Prosencephalon*
;
Rats*
4.Age-related Changes in Anterior, Posterior Corneal Astigmatism in a Korean Population.
Yoon Seob SIM ; Soon Won YANG ; Yu Li PARK ; Kyung Sun NA ; Hyun Seung KIM
Journal of the Korean Ophthalmological Society 2017;58(8):911-915
PURPOSE: To evaluate age-related changes in anterior and posterior corneal astigmatism in Koreans. METHODS: The anterior and posterior corneal astigmatisms of 160 subjects with age ranging from 11 to 92 years, none of whom experienced any complications, were measured with a rotating Scheimpflug camera (Pentacam®). Using this data, the changing proportions of with-the-rule to against-the-rule and changing tendency of anterior and posterior corneal astigmatisms with age were evaluated using polar value analysis according to the Naeser method. RESULTS: For the anterior cornea, the proportion of with-the-rule astigmatisms decreased with age (p < 0.0001). On the other hand, for the posterior cornea, the proportion of against-the-rule astigmatisms decreased with age (p = 0.012). In the polar value analysis, there was a trend toward against-the-rule astigmatism associated with increasing age for the anterior cornea (p < 0.0001) and toward with-the-rule astigmatism for the posterior cornea (p < 0.0001). CONCLUSIONS: In previous studies, the anterior corneal surface shifted from with-the-rule to against-the-rule astigmatism with increasing age, whereas the posterior corneal surface remained as against-the-rule astigmatism in most cases. But, our results showed that the proportion of against-the-rule astigmatisms of the posterior cornea decreased with age. Thus, evaluation of posterior corneal astigmatisms should be performed before cataract surgery in old patients, especially when using a multifocal or toric intraocular lens.
Astigmatism*
;
Cataract
;
Cornea
;
Hand
;
Humans
;
Lenses, Intraocular
;
Methods
5.Diagnostic Patterns and Medical Costs in the Evaluation of Syncope Patients Visiting an Emergency Department.
Hee YOON ; Ji Ung NA ; Tae Gun SHIN ; Min Seob SIM ; Ik Joon JO ; Hyoung Gon SONG ; June Soo KIM
Journal of the Korean Society of Emergency Medicine 2011;22(6):662-668
PURPOSE: Syncope is a common clinical problem. However, diagnosis of the cause of syncope is not simple due to a wide variety of forms of syncope. The aim of this study was to assess current diagnostic methods and the associated medical costs which accompany the evaluation of patients suffering syncope who admitted to an emergency department (ED). METHODS: This study is a prospective, observational, single center study. Patients included in the study visited the ED of a single, tertiary hospital between January and December 2009, and were diagnosed with syncope. We investigated the diagnostic yields (DY) for the tests that were employed and evaluated factors related to medical costs. RESULTS: A total of 124 patients were enrolled in this study. Blood tests, chest radiography, postural blood pressure (BP) measurement and computerized tomography of the brain were performed in over 60% of cases, but DY for each of these tests was less than 3%, except for postural BP measurement (7.4%). The test which demonstrated a relatively high DY was the head-up tilt test (68.1%). The ratio of the cost of each test among the total medical costs required by all patients (constituent ratio) was highest for brain imaging tests (12.2%). The total cost of syncope evaluation per patient was 1,454,000+/-2,865,000 won. Factors including hospital admission and diagnosis of cardiac syncope resulted in significantly higher total medical costs for those patients. CONCLUSION: Among the tests performed in the ED for syncope evaluation, blood tests, chest x-ray and brain imaging tests were commonly used but resulted in relatively low diagnostic yield. Independent factors which increased medical costs were hospital admission and diagnosis of cardiac syncope.
Blood Pressure
;
Brain
;
Emergencies
;
Hematologic Tests
;
Humans
;
Neuroimaging
;
Prospective Studies
;
Stress, Psychological
;
Syncope
;
Tertiary Care Centers
;
Thorax
6.MR Findings of Seizure-Related Cerebral Cortical Lesions during Periictal Period.
Na Yoon KIM ; Hye Jin BAEK ; Dae Seob CHOI ; Jee Young HA ; Hwa Seon SHIN ; Ju Ho KIM ; Ho Cheol CHOI ; Ji Eun KIM ; Mi Jung PARK
Investigative Magnetic Resonance Imaging 2017;21(2):82-90
PURPOSE: This study investigated the MRI, MR angiography (MRA) and MR perfusion findings of seizure-related cerebral cortical lesions during the periictal period. MATERIALS AND METHODS: From a retrospective review of the institutional database between 2011 and 2014, a total of 21 patients were included in this study. Two radiologists assessed periictal MRI, including MRA and MR perfusion, in patients with seizure-related cortical lesions. The parameters examined include: location of cortical abnormality, multiplicity of the affected cortical region, cerebral vascular dilatation, perfusion abnormality and other parenchymal lesions. RESULTS: All patients showed T2 hyperintense cerebral cortical lesions with accompanying diffusion restriction, either unilateral (18/21, 85.7%) or bilateral (3/21, 14.3%). Of the 21 patients enrolled, 10 (47.6%) had concurrent T2 hyperintense thalamic lesions, and 10 (47.6%) showed hippocampal involvement. Of the 17 patients (81%) who underwent MRA, 13 (76.5%) showed vascular dilatation with increased flow signal in the cerebral arteries of the affected cortical regions. On MR perfusion, all 5 patients showed cortical hyperperfusion, corresponding to the region of cortical abnormalities. CONCLUSION: Seizure-related cerebral cortical lesions are characterized by T2 and diffusion hyperintensities, with corresponding cerebral hyperperfusion and vascular dilatation. These findings can be helpful for making an accurate diagnosis in patients with seizure.
Angiography
;
Cerebral Arteries
;
Diagnosis
;
Diffusion
;
Dilatation
;
Humans
;
Magnetic Resonance Angiography
;
Magnetic Resonance Imaging
;
Perfusion
;
Retrospective Studies
;
Seizures
7.MR Findings of Seizure-Related Cerebral Cortical Lesions during Periictal Period.
Na Yoon KIM ; Hye Jin BAEK ; Dae Seob CHOI ; Jee Young HA ; Hwa Seon SHIN ; Ju Ho KIM ; Ho Cheol CHOI ; Ji Eun KIM ; Mi Jung PARK
Investigative Magnetic Resonance Imaging 2017;21(2):82-90
PURPOSE: This study investigated the MRI, MR angiography (MRA) and MR perfusion findings of seizure-related cerebral cortical lesions during the periictal period. MATERIALS AND METHODS: From a retrospective review of the institutional database between 2011 and 2014, a total of 21 patients were included in this study. Two radiologists assessed periictal MRI, including MRA and MR perfusion, in patients with seizure-related cortical lesions. The parameters examined include: location of cortical abnormality, multiplicity of the affected cortical region, cerebral vascular dilatation, perfusion abnormality and other parenchymal lesions. RESULTS: All patients showed T2 hyperintense cerebral cortical lesions with accompanying diffusion restriction, either unilateral (18/21, 85.7%) or bilateral (3/21, 14.3%). Of the 21 patients enrolled, 10 (47.6%) had concurrent T2 hyperintense thalamic lesions, and 10 (47.6%) showed hippocampal involvement. Of the 17 patients (81%) who underwent MRA, 13 (76.5%) showed vascular dilatation with increased flow signal in the cerebral arteries of the affected cortical regions. On MR perfusion, all 5 patients showed cortical hyperperfusion, corresponding to the region of cortical abnormalities. CONCLUSION: Seizure-related cerebral cortical lesions are characterized by T2 and diffusion hyperintensities, with corresponding cerebral hyperperfusion and vascular dilatation. These findings can be helpful for making an accurate diagnosis in patients with seizure.
Angiography
;
Cerebral Arteries
;
Diagnosis
;
Diffusion
;
Dilatation
;
Humans
;
Magnetic Resonance Angiography
;
Magnetic Resonance Imaging
;
Perfusion
;
Retrospective Studies
;
Seizures
8.Effect of serotonin uptake inhibitors on serotonin metabolism in the hypothalamus of freely moving rats.
Yun Seob SONG ; Se Na YOON ; Dong Sik JUNG ; Sang Hee YOO ; Hyong Kyun RYU ; Hyung Gun KIM
The Korean Journal of Physiology and Pharmacology 2000;4(6):439-444
Tricyclic antidepressant clomipramine or selective serotonin reuptake inhibitors (SSRIs) have been commonly used for the treatment of premature ejaculation. In the present study, we analyzed the concentrations of serotonin and 5-hydroxyindoleacetic acid (5-HIAA) in the medial preoptic area (MPOA) of the hypothalamus by awakening animal microdialysis following administration of clomipramine and various SSRIs. We then compared the serotonin metabolism and clinical effects of clomipramine and SSRIs on premature ejaculation. Basal extracellular serotonin level in the MPOA was higher than other brain regions and it was significantly increased by clomipramine and the SSRIs. The rank order of the concentration of serotonin at the MPOA was clomipramine, sertraline, paroxetine and fluoxetine and the concentrations of 5-HIAA was vice versa. The changes in serotonin concentration at the MPOA appeared closely associated with the clinical effects of these drugs on premature ejaculation. These results suggest that the serotonergic neuronal activity in the MPOA may have an selective inhibitory influence on ejaculation, and the effects of clomipramine and SSRIs on erectile function are mainly mediated by MPOA of the hypothalamus.
Animals
;
Brain
;
Clomipramine
;
Ejaculation
;
Fluoxetine
;
Hydroxyindoleacetic Acid
;
Hypothalamus*
;
Male
;
Metabolism*
;
Microdialysis
;
Paroxetine
;
Premature Ejaculation
;
Preoptic Area
;
Rats*
;
Serotonergic Neurons
;
Serotonin Uptake Inhibitors*
;
Serotonin*
;
Sertraline
9.Causes of food allergy according to age and severity: A recent 10-year retrospective study from a single tertiary hospital
Eunjoo LEE ; Kyunguk JEONG ; Yoo-Seob SHIN ; Dong-Ho NAHM ; Hae-Sim PARK ; Hyun-Na CHOI ; Jiwon YOON ; Young-Min YE ; Sooyoung LEE
Allergy, Asthma & Respiratory Disease 2020;8(2):80-88
Purpose:
Recent studies of food allergy (FA) at all ages are scanty in Korea. We performed this study to better understand severity-related and age-stratified causes of FA from infants to older adults in a single tertiary hospital in Korea.
Methods:
A retrospective medical record review was performed on patients of all ages diagnosed with immediate-type FA between March 2008 and February 2018 in Ajou University Hospital.
Results:
A total of 4,680 cases of FA among 2,733 patients were reported. The distribution of onset ages of the first FA symptom was as follows: 45.3% below 2 years, 16.2% at 2–6 years, 5.5% at 7–12 years, 4.0% at 13–18 years, 16.9% at 19–40 years, 10.4% at 41–65 years, and 1.8% above 65 years of age. The major 10 causative foods were hen’s eggs (17.2%), cow’s milk (16.7%), wheat (8.6%), crustaceans (8.5%), fish (4.6%), walnuts (4.4%), pork (3.2%), peanuts (3.2%), shellfish (3.0%), and peach (2.2%). The culprits ranked from the 11th to the 20th were as follows: soybean, apple, chicken, buckwheat, beef, kiwi, almonds, perilla seeds, tomato, and squid. The top 3 causative foods in children were hen’s eggs, cow’s milk, and wheat, while those in adults were crustaceans, wheat, and fish. Food-induced anaphylaxis was reported in 29.2% of all cases, with cow’s milk, hen’s eggs, wheat, crustaceans, fish, walnuts, pork, shellfish, buckwheat, and peanuts being the major 10 causes.
Conclusion
This study could provide a better understanding of the detailed ranks of the causes of FA according to severity and age in Korea.
10.Aortoventriculoplasty with The Pulmonary Autograft: The "Ross-Konno" Procedure: 1 case report.
Woong Han KIM ; Young Thak LEE ; Seob LEE ; Jung Hyeun BANG ; Wook Sung KIM ; Jae Chun SHIM ; Cheol Hyun CHUNG ; Chan Young NA ; Yoon Seop JEONG ; Jae Jin HAN ; Do Hyun JUNG ; Il Sang JUNG ; Jung Won PARK ; Young Kwan PARK ; Sung Nok HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(4):419-422
In small children with left ventricular outflow tract obstruction, a few methods of surgical treatment could be considrred. The pulmonary autogrart provides a promising options for aortic valve replacement as part of the aortoventriculoplasty procedure in children. We report a successfully treated congenital aortic stcnoinsufricicncy with severe left ventricular dysfunction in an early infant with the aortoventriculoplasty using thc pulmonary autograft (the Ross-Konno procedure).
Aortic Valve
;
Autografts*
;
Child
;
Dronabinol
;
Humans
;
Infant
;
Transplantation, Autologous
;
Ventricular Dysfunction, Left
;
Ventricular Outflow Obstruction