2.Investigation of antigen related to the in vitro invasiveness of salmonella typhimurium through the Madin-Darby canine kidney(MDCK) epithelial cell monolayer.
Chung Gyu PARK ; Eung Soo HWANG ; Ju Young SEOH ; Yoon Hoh KOOK ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1991;26(6):553-562
No abstract available.
Epithelial Cells*
;
Salmonella typhimurium*
;
Salmonella*
3.A case of immature teatama of ovary, with dermoid cyst and tubal pregnancy of controlateral adnexa.
Kook Young KONG ; Sei Kwon JANG ; Yoon Jung KIM ; Jee Yeon LEE ; Jwa Koo CHUNG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1664-1668
No abstract available.
Dermoid Cyst*
;
Female
;
Ovary*
;
Pregnancy
;
Pregnancy, Tubal*
4.Characterization of monoclonal antibodies against human cytomegalovirus(HCMV) glycoprotein.
Eung Soo HWANG ; Ju Young SEOH ; Chung Gyu PARK ; Yoon Hoh KOOK ; Chang Yong CHA
Journal of the Korean Society for Microbiology 1992;27(6):545-553
No abstract available.
Antibodies, Monoclonal*
;
Glycoproteins*
;
Humans*
5.The Effect of Induced Hypotension with Sodium Nitroprusside on Alveolar-srterial Oxygen Tension Difference and Pulmonary Shunting.
Korean Journal of Anesthesiology 1985;18(4):394-402
The effect of induced hypotension with sodium nitroprusside(SNP) on alveolar-arterial oxygen tension difference and pulmonary shunting in 10 surgical patients with normal pulmonary function was studied under general anesthesia. Heart rate, mean arterial pressure, central venous pressure, blood gases and hemoglobin were measured before, during and after SNP infusion. Using the above data, alveolar-arterial oxygen tension difference and pulmonary shunting were calculated. The results were as follows. 1) Mean arterial pressure decreased significantly from 98+/-9.1mmHg before SNP infusion to 61+/-3.0 mmHg during SNP infusion(p<0.001), and increased to 96+/-6.7mmHg again after SNP infusion. 2) Heart rate increased significantly from 78+/-10.5 beats/min. to 101+/-11.9 beats/min.(p<0.001), and decreased to 84+/-11.5 beats/min. again. 3) Arterial oxygen tension decreased from 489+/-32.5mmHg to 480+/-25.0mmHg, but was not statistically significant. (p>0.05). 4) Alveolar-arterial oxygen tension difference increased from 188+/-29.0mmHg to 196+/-25.0mmHg, but was not statistically significant(p>0.05). 5) Pulmonary shunting increased from 9.0+/-1.83% to 9.2+/-1.50%, but was not statistically significant.(p>0.05). The above findings suggest that pulmonary shunting in patients with normal lung function will not affected during induced hypotension with SNP.
Anesthesia, General
;
Arterial Pressure
;
Central Venous Pressure
;
Gases
;
Heart Rate
;
Humans
;
Hypotension*
;
Lung
;
Nitroprusside*
;
Oxygen*
;
Sodium*
6.The Effects of Bone Grafts using Platelet Rich Plasma on Infrabony Defects.
Yoon Jun HUR ; Chin Hyung CHUNG ; Sung Bin LIM
The Journal of the Korean Academy of Periodontology 2001;31(2):489-499
Bone graft and guided tissue regeneration have been used for the regeneration of periodontal tissue which is the ultimate goal of periodontal treatment. Recently, it was reported that some kind of growth factors were used for regeneration. Platelet rich plasma was researched that it could increase the density of bone and the rate of bone regeneration. For that, 25 patients which have pocket depth more than 5mm at any of 6 surfaces, of healthy patient without any systemic disease were treated. Biogran? were grafted into 14 infrabony pockets as controls, and Biogran(R) with PRP were inserted into 31 infrabony pockets. And then, follwing evaluations were made at the end of 1, 3 and 6 months. 1.There was no statistical difference between control and experimental group in pocket depth, gingival recession, minimum probing attachment level and maximum probing attachment level at preoperation(p>0.05). 2.Decrease in probing pocket depth were reduced to 3.32mm for experimental group and 2.71mm for control group. The decrease was evident at the end of 1 month, they were 2.97mm and 2.29mm, and it was statistically difference(p<0.05). 3.Gingival recession was increased by 0.55mm in experimental group and 0.50mm in control group, it was evident at the end of 1 month. And it was statistically difference(p<0.05). 4.Minimum probing attachment level was increased by 0.35mm in experimental group and 0.36mm in control group, it was statistically difference(p<0.05). 5.Maximum probing attachment level was decreased by 3.19mm in experimental group and 2.93mm in control group, it was statistically difference(p<0.05). 6.There was no statistical difference between control and experimental group in pocket depth, gingival recession, minimum probing attachment level and maximum probing attachment level(p>0.05). There was statistical difference in decrease of pocket depth between pre-operation and 1 month after post-operation(p<0.05). In conclusion, bone graft using Biogran? and bone graft using Biogran? with platelet rich plasma were both effective in treatment of infrabony pocket, bone graft using Biogran? with platelet rich plasma was more effective in early soft tissue healing.
Blood Platelets*
;
Bone Regeneration
;
Gingival Recession
;
Guided Tissue Regeneration
;
Humans
;
Intercellular Signaling Peptides and Proteins
;
Platelet-Rich Plasma*
;
Regeneration
;
Transplants*
7.Tubal pregnancy following laparoscopic tubal sterilization: a study of the pathogenesis and treatment.
Tae Ho CHUNG ; Seug Young KIM ; Dong Jae CHO ; Woo Hee JUNG ; Yoon Ho LEE ; Kook LEE ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(2):200-207
No abstract available.
Female
;
Pregnancy
;
Pregnancy, Tubal*
;
Sterilization, Tubal*
8.Eukaryotic Kxpression of the Major Antigenic Determinants Evoking Neutralizing Antibodies in Human Cytomegalovirus ( HCMV ) Isolated in Korea.
Chung Gyu PARK ; Yoon Hoh KOOK ; Chang Yong CHA ; Eung Soo HWANG ; Dong Gyun LIM ; Jae Won PARK
Journal of the Korean Society for Microbiology 1997;32(3):315-324
Human cytomegalovirus (HCMV) isolated from Korean patients is different in the antigenic and genomic structure of gB from the laboratory-adapted strain. To dissect the reactivity to HCMV glycoprotein B (gB) domains, each domain gene of gB of HCMV SNUCH1, Korean isolate, was amplified from the extracted DNA of the virus-infected fibroblasts with the specific primers by polymerase chain reaction (PCR). Amplified DNA was cloned into pcDNA3. Immunofluorescent staining and western blot analysis revealed that the expressed gB in mammalian cells was immunoreactive and equivalent to the naturally expressed gB in virus-infected fibroblasts. The antigenic component reactive with monoclonal antibodies, MCMVA 57, 88, and 98 appeared at the D3 domain of gB molecule, and that with MCMVA 66 and 135 at the D2b domain. Antibody titer was measured with HCMV-infected fibroblasts and the domains of gB expressed in mammalian cells. There was no correlation between the antibody titer to the whole HCMV and neutralizing antibody titer, and between the antibody titer to whole HCMV and whole gB. It was more reasonable to use whole gB than whole HCMV in the comparison with the neutralizing antibody titer. D3 was representative domain in gB molecule in the anti-gB reactivity. Conclusively it is highly recommendable to use the representing isolates in Korea and its domains for the detection of antibody or the analysis of antigen in the aspect of immunological properties and molecular structures.
Antibodies, Monoclonal
;
Antibodies, Neutralizing*
;
Blotting, Western
;
Clone Cells
;
Cytomegalovirus*
;
DNA
;
Epitopes*
;
Fibroblasts
;
Glycoproteins
;
Humans*
;
Korea*
;
Molecular Structure
;
Polymerase Chain Reaction
9.Relationship between Severity of Dementia and Behavioral Psychopathology in Probable Alzheimer's Disease.
Jung Hyun YOON ; Baik Seok KEE ; Bum Woo NAM ; Sang Kook KIM
Journal of Korean Geriatric Psychiatry 1998;2(1):73-77
Behavioral problems are thought to be pervasive and devasting to patients with dementia of the Alzheimer's type and their families. Despite this, little empirical data are available concerning the nature of such impairments, their rate of occurrence or their relationship to the disease process. This study was designed to investigate the nature and the rates of behavioral disturbance among DAT patients. The subjects involved in this study were 72 patients who were hospitalized and had primary diagnosis of dementia of the Alzheimer's type. Severity of the dementia was assessed by MMSE, and abnormal behavior by E-BEHAVE-AD. Pearson correalation was used to analysis data. The subjects were divided into mild/moderate dementia group and severe, and then evaluated significant differences. Independent-samples T-test was used to analysis data. The results were as follows: 1) Wandering and delusional ideation were associated with declining MMSE score 2) Wandering was only differenciated between mild to moderate group. In conclusion, problems found associated with level of impairment such as wandering and delusion are thought to be characteristic of the disease and therefore predictable. Problems found not associated with level of impairment, are likely to be idiosyncratic. The former should probably be incorporated into education and intervention programs, the latter addressed as needed on an individual basis.
Alzheimer Disease*
;
Delusions
;
Dementia*
;
Diagnosis
;
Education
;
Humans
;
Psychopathology*
10.Relationship between Severity of Dementia and Behavioral Psychopathology in Probable Alzheimer's Disease.
Jung Hyun YOON ; Baik Seok KEE ; Bum Woo NAM ; Sang Kook KIM
Journal of Korean Geriatric Psychiatry 1998;2(1):73-77
Behavioral problems are thought to be pervasive and devasting to patients with dementia of the Alzheimer's type and their families. Despite this, little empirical data are available concerning the nature of such impairments, their rate of occurrence or their relationship to the disease process. This study was designed to investigate the nature and the rates of behavioral disturbance among DAT patients. The subjects involved in this study were 72 patients who were hospitalized and had primary diagnosis of dementia of the Alzheimer's type. Severity of the dementia was assessed by MMSE, and abnormal behavior by E-BEHAVE-AD. Pearson correalation was used to analysis data. The subjects were divided into mild/moderate dementia group and severe, and then evaluated significant differences. Independent-samples T-test was used to analysis data. The results were as follows: 1) Wandering and delusional ideation were associated with declining MMSE score 2) Wandering was only differenciated between mild to moderate group. In conclusion, problems found associated with level of impairment such as wandering and delusion are thought to be characteristic of the disease and therefore predictable. Problems found not associated with level of impairment, are likely to be idiosyncratic. The former should probably be incorporated into education and intervention programs, the latter addressed as needed on an individual basis.
Alzheimer Disease*
;
Delusions
;
Dementia*
;
Diagnosis
;
Education
;
Humans
;
Psychopathology*