No abstract available.
Pneumonia*

No abstract available.
Adult* ; Bronchoscopy* ; Foreign Bodies* ; Humans

No abstract available.
Pancreas*

No abstract available.
Electrodes* ; Neural Conduction* ; Suction*

OBJECTIVES: Anticardiolipin antibody (ACA) and lupus anticoagulant (LA) are acquired antiphospholipid antibodies (APAs), which are regarded as important risk factors far vascular thrombosis and recurrent fetal loss. Although the clinical relevance of APAs in dialysis patients is uncertain, recent studies have suggested that APAs are involved in bioincompatibility and thrombogenic complications in hemadialysis (HD) patients. METHOD: We performed a cross sectional study of ACA and LA in 50 stable HD patients and their 68 vascular accesses (52 native arteriovenous fistulae and 16 synthetic arterovenous grafts), with the analysis of factors associated with the presence of APAs and the retrospective evaluation of vascular access occlusion (VAO). LA was assessed by platelet neutralization method whereas IgG-ACA was measured by a solid phase ELISA. Values higher than 23GPLU/ml (IgG phospholipid units) were considered to be positive for IgG-ACA and positive values for LA was more than 8 seconds in prolongation of the clotting time with human platelet lysate. Vascular access survival was assessed by Kaplan- Meier method, RESULTS: The mean age of the subject (M:F 21:29) was 46 years and the mean duration of hemodialysis was 49 months. The frequency of VAO in entire subjects was 0.45+/-0.98 episodes/patient year. The median value of IgG-ACA was 16.0 GPLU/ml with a distribution from 2.7 to 46.1GPLU/ ml. The median titer of I.A was 4.5 (3.1-45.6) seconds. Fourteen patients (28%) were found to have at least one episode of VAO. In spite of comparable clinical and biochemical data according to the presence of VAO, the titers of IgG-ACA (13.6+/-7.7 vs, 20.3+/-8.7GPLIJ/ml, P<0.05) and LA (4.5+/-2.9 vs. 11.7 +/-12.6sec, P<0.05) were significantly higher in VAO group. Six out of 50 patients(12%) had an increased titer of IgG-ACA and LA was found in 11 patients(22%). No patients were positive for ACA and LA simultaneously. There was no significant difference in sex, etiology of ESRD, diabetic status, the dosage of heparin during HD or the amount of erythropoietin administered according to the presence of APAs. We could not find any significant correlation between the titer of APAs and age, duration of dialysis, blood pressure, platelet count and biochemical parameters. In the patients with positive ACA, the frequency of VAO was 1.05+/-0.12 episodes/patient year, which was significantly higher than patients without ACA (0.33+/-0.17 episodes/ patient year, P<0.05). In the patients with the presence of LA(1.06+/-0.43 vs. 0.12+/-0.06 episodes/ patients year, P<0.01). The median vascular access survival time in IgG-ACA positive patients (32.7 months) was significantly decreased compared to 66.8 months in IgG-ACA negative group. CONCLUSION: Our data suggest that the presence of APAs (ACA and/or LA) affects the event-free vascular access survival in HD patients. Therefore the evaluation of APAs status have to be included in the diagnostic strategies for the patients with recurrent VAO. Further studies are necessary to explore the pharmacologic intervention method to decrease APAs and prevent VAO in HD patients.
Antibodies, Anticardiolipin* ; Antibodies, Antiphospholipid ; Arteriovenous Fistula ; Blood Platelets ; Blood Pressure ; Dialysis ; Enzyme-Linked Immunosorbent Assay ; Erythropoietin ; Heparin ; Humans ; Kidney Failure, Chronic ; Lupus Coagulation Inhibitor* ; Platelet Count ; Renal Dialysis* ; Retrospective Studies ; Risk Factors ; Thrombosis

No abstract available.

Many patients present simultaneously with visually significant (to the patient and surgeon) lens opacities and vitreoretional disease. Traditional management of this problem has included two operations: vitrectomy followed by cataract extraction or cataract extraction followed by vitrectomy. Visual rehabilitation of aphakic eyes after pars plana vitrectomy is often difficult when anatomic objectives are achieved. Intraocular lens provides more natural and convenient vision. Now, simultaneous cataract extraction and lens implantation during pars plana vitrectomy can be considered. We performed posterior chamber lens insertion in the ciliary sulcus after completion of pars plana lensectomy, vitrectomy, and removal of intraocular foreign body. During pars plana lensectomy, we left the anterior lens capsule and zonules intact. After posterior chamber lens insertion, we removed the central anterior lens capsules from behind the optical component leaving a peripheral rim to support the haptics. The procedure provided good pseudophakic vision.
Capsules ; Cataract ; Cataract Extraction ; Foreign Bodies ; Humans ; Lens Implantation, Intraocular* ; Lenses, Intraocular* ; Optical Devices ; Rehabilitation ; Vitrectomy*

PURPOSE: Insulin-like growth factor(IGF-I) and IGF binding protein(IGFBP)-3 is thought to play an important role in fetal erythropoiesis. The objective of this study was to establish a relation between IGF-I, free IGF-I, IGFBP-1, and -3 with hemoglobin level in healthy term, 3-month, and 12-month old infants. METHODS: Healthy term infants(n=20)were enrolled at birth, as well as 3 months Erythropoiesis ; Growth Hormone ; Humans ; Infant* ; Insulin-Like Growth Factor Binding Protein 1 ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor I ; Parturition

No abstract available.
Colon* ; Humans* ; Substance P* ; Tetrodotoxin*

The deoxyribonucleic acid content was determined in 50 cases of renal cell carcinoma by means of flow cytometric analysis of paraffin-embedded specimens. Of these, 22 cases (44%) were diploid and 28 cases (56% ) were aneuploid. The incidence of aneuploid pattern according to histological grade was 38% in high grade and 75% in low grade with statistical difference. The ploidy status did not correlate with tumor stage, tumor cell type or presence of microvascular invasion. Of 22 cases in which two separate specimens were analyzed from each primary tumor. intratumoral heterogeneity of ploidy status was observed in 9 cases(41%). Of 13 cases in which specimens from both primary tumor and regional metastatic lesions were analyzed, intertumoral heterogeneity was observed in 8 cases(62%). A close correlation between tumor stage and prognosis was observed. The prognostic difference according to histological grade. tumor cell type or presence ol microvascular invasion was statistically unacceptable. The 5-year survival rate according to ploidy status was 77% in diploid tumors and 47% in aneuploid tumors with statistical significance, but no significant difference in overall survival was observed. Among the patients without metastasis of renal cell carcinoma. those with diploid tumors had better prognoses in comparison to those with aneuploid tumors. Conclusively, DNA content in renal cell carcinoma analyzed by FCM had shown the coexistence of intratumoral and intertumoral heterogeneities and is considered to be an important prognostic stratifier in renal cell carcinoma without metastasis.
Aneuploidy ; Carcinoma, Renal Cell* ; Diploidy ; DNA* ; Flow Cytometry ; Humans ; Incidence ; Neoplasm Metastasis ; Ploidies ; Population Characteristics ; Prognosis ; Survival Rate