1.16S Ribosomal RNA Identification of Prevotella nigrescens from a Case of Cellulitis.
John Jeongseok YANG ; Tae Yoon KWON ; Mi Jeong SEO ; You Sun NAM ; Chung Soo HAN ; Hee Joo LEE
Annals of Laboratory Medicine 2013;33(5):379-382
No abstract available.
Acupuncture Therapy
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Ampicillin/pharmacology/therapeutic use
;
Ankle/ultrasonography
;
Anti-Bacterial Agents/pharmacology/therapeutic use
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Cellulitis/complications/diagnosis/drug therapy/*microbiology
;
Diabetes Mellitus, Type 2/complications
;
Gram-Negative Bacterial Infections/complications/diagnosis/drug therapy/*microbiology
;
Humans
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Hypertension/complications
;
Magnetic Resonance Imaging
;
Male
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Microbial Sensitivity Tests
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Middle Aged
;
Prevotella nigrescens/drug effects/*genetics/isolation & purification
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RNA, Ribosomal, 16S/*analysis
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Sulbactam/pharmacology/therapeutic use
;
Tomography, X-Ray Computed
2.The Attention of Primary Physician on Depression of the Elderly Patients.
Young Seong KIM ; Eon Sook LEE ; Jung Han CHUN ; Yang Hyun KIM ; Min Gyu KIM ; Jong Soo HWANG ; Yoon John YANG ; Sang Woo OH ; Yeong Sook YOON
Journal of the Korean Academy of Family Medicine 2004;25(11):818-825
BACKGROUND: It has been known that the prevalence of depression is increasing and depressive mood is accompanied with various physical symptoms in the elderly. In this research, we studied various physical symptoms of the elderly patients and how many of those symptoms were associated to depressive mood. We also investigated how much their doctors were concerned about depressive symptoms of the patients. METHODS: The subjects were 135 patients over 60 years old, who visited geriatric center and department of family medicine in a university hospital from December 2002 to May 2003. Individual interviews were conducted among the subjects and all symptoms who suffered from within a month from the time of inter view, depression score, stress score, functional status and their sociodemographic factors were assessed. Finally, doctor's diagnosis or comments on depressive mood were assessed based on the medical documents of the elderly patients with depression. RESULTS: 56% of the subjects had depressive mood. Common symptoms of subjects were memory impairment, visual disturbance, fatigue, arthralgia, and thirsty sense. The more depressive mood the elderly have, the more physical symptoms they have. The physician paid their attention to depressive mood in 13% of the cases among the elderly with depressive mood. Depressive mood was affected by whom they lived together with, regular exercise and stress. CONCLUSION: This study shows that most of the elderly patients had depressive mood and their common symptoms were associated to depressive mood. The stress and living together with their children were risk factors for depression of the elderly. However, depressive mood was less found among those patients who had spouse and who exercised regularly. Though physicians more likely recognize the depressive mood of the elderly as depression was severer, still little attention was paid to depressive mood in the elderly.
Aged*
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Arthralgia
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Child
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Depression*
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Diagnosis
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Fatigue
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Humans
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Memory
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Prevalence
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Risk Factors
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Spouses
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Vision Disorders
3.Current State and Demand of Esophagogastroduodenoscopy Training in Family Practice Residency Programs.
Jung Han CHUN ; Yeong Sook YOON ; Sang Woo OH ; Eon Sook LEE ; Min Gyu KIM ; Young Seong KIM ; Yang Hyun KIM ; John YANG
Journal of the Korean Academy of Family Medicine 2003;24(12):1092-1098
BACKGROUND: Most recently, there is an increased use of EGD (esophagogastroduodenoscopy) for primary care among family physicians, which tends to promote EGD training programs in the course of Family Practice Residency. This study determined to survey current status of EGD training programs among residents in family medicine, identify relevant problems, and present some suggestions for their improvement. METHODS: The subjects were residents selected among family medicine training hospitals, which were registered in the KAFM (Korean Academy of Family Medicine). The residents were in their 3rd year of training or had already completed the EGD training program. Surveys were sent out to those hospitals by mail and electronic mail surveys were performed by researchers. RESULTS: Among 66 subject hospitals a total of 27 surveys (40.9%) were returned. Most EGD training were performed in the department of internal medicine. The mean duration of training period was 8 weeks. The averale number of hands on experience of the procedure was 62. It was found that most residents thought that EGD training period and the number of hands on experience of the procedure were insufficient. The longer period of actual experience of the procedure and the more number of EGD caseloads they had, the more they were satisfied with their EGD training programs. It was also found that there was a high demand for a follow-up learning opportunities for EGD (p<.05), because the residents who had already had many EGD caseloads further wanted to receive continuous education even, after they acquired license. There were no relationships observation period, period of actual experience of the procedure, and number of EGD caseloads during residency with demand for follow-up learning opportunities. CONCLUSION: In summary, there was insufficient EGD training period and actual experience of the EGD procedure in family practice residency. There was low satisfaction of EGD training programs and high demand for continuous education. Therefore, it is recommended to establish EGD training program, proper practice training, and regular continuing education after completing residency.
Education
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Education, Continuing
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Electronic Mail
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Endoscopy, Digestive System*
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Family Practice*
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Hand
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Humans
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Internal Medicine
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Internship and Residency*
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Learning
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Licensure
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Physicians, Family
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Postal Service
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Primary Health Care
4.Detection of RUNX1-MECOM Fusion Gene and t(3;21) in a Very Elderly Patient Having Acute Myeloid Leukemia with Myelodysplasia-Related Changes.
John Jeongseok YANG ; Sun Young CHO ; Jin Tae SUH ; Hee Joo LEE ; Woo In LEE ; Hwi Joong YOON ; Sun Kyung BAEK ; Tae Sung PARK
Annals of Laboratory Medicine 2012;32(5):362-365
An 87-yr-old woman was diagnosed with AML with myelodysplasia-related changes (AML-MRC). The initial complete blood count showed Hb level of 5.9 g/dL, platelet counts of 27x10(9)/L, and white blood cell counts of 85.33x10(9)/L with 55% blasts. Peripheral blood samples were used in all the tests, as bone marrow examination could not be performed because of the patient's extremely advanced age and poor general health condition. Flow cytometric analysis, chromosome analysis, FISH, and reverse transcriptase-PCR (RT-PCR) results indicated AML-MRC resulting from t(3;21) with the RUNX1-MECOM fusion gene. To our knowledge, this is the second most elderly de novo AML patient associated with t(3;21) to be reported.
Aged, 80 and over
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Blood Cells/pathology
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Chromosomes, Human, Pair 21
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Chromosomes, Human, Pair 3
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Female
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Humans
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Karyotyping
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Leukemia, Myeloid, Acute/complications/*diagnosis/genetics
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Multiplex Polymerase Chain Reaction
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Myelodysplastic Syndromes/complications/*diagnosis/genetics
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Oncogene Proteins, Fusion/*genetics
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Sequence Analysis, DNA
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*Translocation, Genetic
5.A Case of Chronic Recurrent Small Bowel Bleeding in Neurofibromatosis Type 1 Diagnosed by Capsule Endoscopy.
Byung Min JOHN ; Sang Jeong YOON ; Ana KIM ; Hyun Ung YANG ; Chang Nam KIM ; Ju Hun KIM ; Seong Kyu PARK
Korean Journal of Gastrointestinal Endoscopy 2005;31(1):53-57
Small bowel diseases comprised of neoplasm, inflammatory disease, vascular abnormality, absorption dysfunction, and iatrogenic causes. Among those, vascular abnormality is perhaps the most important clinical disease entity. Obscure gastrointestinal bleeding accounts for 5% of chronic gastrointestinal bleeding, but conventional endoscopy and radiologic study may fail to diagnose the cause in certain cases. Patients with neurofibromatosis type 1 have a lot of gastrointestinal tumor, with a high incidence of small bowel involvement. We experienced a case presenting with chronic bleeding due to jejunal gastrointestinal stromal tumor diagnosed by capsule endoscopy in a seventy-two year old female patient with sporadic neurofibromatosis type 1.
Absorption
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Capsule Endoscopy*
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Endoscopy
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Female
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Gastrointestinal Stromal Tumors
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Hemorrhage*
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Humans
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Incidence
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Neurofibromatoses*
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Neurofibromatosis 1*
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Vascular Diseases
6.A Case of Limy Bile Associated with Cholangitis and Calcified Gallbladder.
Gyu Yup HWANG ; Anna KIM ; Sang Jeong YOON ; Sung Hee JUNG ; Byeong Seong KO ; Hyeon Woong YANG ; Byung Min JOHN
Korean Journal of Gastrointestinal Endoscopy 2005;31(1):58-61
Limy bile is characterized by excessive precipitation of calcium carbonate, and generally preceded by gallbladder obstruction. Three case reports have been found in the domestic literatures. It is rare that limy bile syndrome associates cholangitis or calcified gallbladder. We report the case of a patient with limy bile, located in the gallbladder, common bile duct, and intrahepatic duct, with association of calcified gallbladder. This case showed characteristic radiologic and endoscopic findings. The patient was treated by endoscopic sphincterotomy and laparoscopic cholecystectomy.
Bile*
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Calcium Carbonate
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Cholangitis*
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Cholecystectomy, Laparoscopic
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Common Bile Duct
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Gallbladder*
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Humans
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Sphincterotomy, Endoscopic
7.Liver Abscess Caused by Gemella morbillorum.
Hyo Jung NAM ; Sang Jeong YOON ; Byung Min JOHN ; Sung Hee JUNG ; Anna KIM ; Byeong Seong KO ; Hyeon Woong YANG ; Kue Yup HWANG ; Jung Yoon LEE ; Sae Hee KIM ; Dong Jin KIM ; Nae Yoo KIM ; Sin Hyung LIM
The Korean Journal of Gastroenterology 2005;46(1):56-59
Gemella morbillorum, an anaerobic-to-aerotolerant Gram-positive coccus, is a normal flora of the oral cavity, respiratory tract, urogenital organ and gastrointestinal tract, and infections caused by this organism are unusual. It has been associated mainly with endocarditis and bacteremia, and rarely with arthritis, spondylodiscitis, meningitis, brain abscess and septic shock. Liver abscess caused by G. morbillorum is very rare, and only a few cases were reported. We experienced a case of liver abscess by G. morbillorum in a 56-year-old woman presented with fever. We report this case with a review of literatures.
Female
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Gram-Positive Bacterial Infections/*diagnosis
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Humans
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Liver Abscess/diagnosis/*microbiology
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Middle Aged
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*Staphylococcaceae
;
Tomography, X-Ray Computed
8.Endoscopic Diagnosis of Nonpedunculated Dysplasia during Surveillance of Ulcerative Colitis: A Survey-Based Multinational Study
Dong-Hoon YANG ; Sneha JOHN ; Fujishiro MITSUHIRO ; Jae Myung CHA ; Jeong-Sik BYEON ; Hyung Wook KIM ; Hyun Gun KIM ; Shai FRIEDLAND ; Yon Xian KOH ; Jin-Young YOON ; Min-Seob KWAK ; Byong Duk YE ; Jihun KIM ; Suk-Kyun YANG
Gut and Liver 2020;14(5):611-618
Background/Aims:
Endoscopic diagnosis of dysplasia or colitic cancer in patients with ulcerative colitis (UC) is more challenging than that of colorectal neoplasia in non-colitic patients. We aimed to evaluate the accuracy of the endo-scopic diagnosis of “nonpedunculated” dysplasia or colitic cancer in UC patients.
Methods:
Ten endoscopists from four countries were surveyed using photographs of 61 histologi-cally confirmed dysplastic or non-dysplastic lesions retrieved from the UC registry database of Asan Medical Center. The participants provided their assessment based on the given photographs and their intention to perform biopsy.
Results:
The overall diagnostic performance of the 10 participants is summarized as follows: sensitivity of 88.2% (95% confidence interval [CI], 84.3% to 91.5%), specificity of 34.8% (95% CI, 29.1% to 40.8%), positive predictive value of 63.0% (95% CI, 60.8% to 65.2%), negative predictive value of 70.2% (95% CI, 62.7% to 76.6%), and accuracy of 64.6% (95% CI, 60.7% to 68.4%). The interobserver agreement on the inten-tion to perform a biopsy was poor (Fleiss kappa=0.169). Of the three endoscopic characteristics of the lesions, includ-ing ulceration, distinctness of the borders, and pit patterns, only neoplastic pit patterns were significantly predictive of dysplasia (odds ratio, 3.710; 95% CI, 2.001 to 6.881). The diagnostic sensitivity and specificity of neoplastic pit patterns were 68.2% (95% CI, 63.0% to 73.2%) and 63.3% (95% CI,57.3% to 69.1%), respectively.
Conclusions
Diagnostic per-formance based on the endoscopist’s intention to perform a biopsy for nonpedunculated potentially dysplastic lesions in UC patients was suboptimal according to this survey-based study.
9.Choledocho-duodenal Fistula Caused by Tuberculosis.
Sang Jeong YOON ; Byung Min JOHN ; Sung Hee JUNG ; Anna KIM ; Byeong Seong KO ; Hyeon Woong YANG ; Young Sook PARK ; Hoon GO ; Gi Young CHOI ; Jun Hyoung KIM ; Jae Min LEE ; Hyo Jung NAM ; Soon Hyun PARK
Korean Journal of Gastrointestinal Endoscopy 2005;30(5):286-289
Choledocho-duodenal fistula is a rare condition. It is usually developed as a complication of the gallstone disease, and rarely developed by penetrating peptic ulcer, trauma and neoplasm. Tuberculosis as a etiology of choledocho-duodenal fistula is very rare, and only a few cases were reported. We experienced a case of choledocho-duodenal fistula due to tuberculous lymphadenitis in a 26 year-old man presented with epigastric pain. After 6 months of anti-tuberculous medication, He was free of symptom and the fistula was closed spontaneously. We report the case with a review of literatures.
Adult
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Fistula*
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Gallstones
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Humans
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Peptic Ulcer
;
Tuberculosis*
;
Tuberculosis, Lymph Node
10.A Case of Subphrenic Abscess with Ileal Fistula Caused by Metastatic Adenocarcinoma of Unknown Origin .
Gi Young CHOI ; Anna KIM ; Chang Nam KIM ; Sang Jeong YOON ; Sung Hee JUNG ; Byeong Seong KO ; Hyeon Yoong YANG ; Byung Min JOHN ; Seok Hyun KIM ; Hyo Jung NAM ; Hoon GO
The Korean Journal of Gastroenterology 2005;46(6):471-474
Usual sources of subphrenic abscess with intestinal fistula are previous abdominal operation, inflammatory bowel disease and malignancy. Reported cases of intestinal fistula caused by adenocarcinoma were complicated by direct invasion. In this report, a 70-year-old male had a subphrenic abscess with intestinal fistula and the cause was a metastatic adenocarcinoma of unknown origin. As far as we know, this has not been reported previously in the literatures. The abscess went on chronic course for six months because intermittent administration of antibiotics modified its clinical presentation. The fistulous tract between the abscess and ileum was demonstrated by tubogram via the drainage catheter in abscess. The patient underwent surgical treatment because the cause of fistula was obscure. Invasion of the ileum by metastatic adenocarcinoma was diagnosed by the histologic examination of surgical specimen. Therefore, when a fistula develops without any apparent cause, there is a possibility of malignancy, and surgical approach must be considered. An early surgical approach will prevent the delay in treatment and reduce the mortality.
Adenocarcinoma/complications/diagnosis/*secondary
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Aged
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English Abstract
;
Humans
;
Ileal Diseases/diagnosis/*etiology
;
Ileal Neoplasms/complications/diagnosis/*secondary
;
Intestinal Fistula/diagnosis/*etiology
;
Male
;
*Neoplasms, Unknown Primary
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Subphrenic Abscess/diagnosis/*etiology