No abstract available.
Tuberculosis, Lymph Node*

In this study, the relationship between the awareness of blood program and the blood donation experience has been studied to know whether they corelate or not. The awareness of blood program was divided into 4 areas of knowledge and measured: the eligibilityt of blood donation, knowledge about blood, blood donation program, and general facts about blood donation. The experience of blood donation was divided into 3 groups: the registered donor, the non-registered donor, and the nondonor. The result in this study shows that the awareness of blood program is related with 3 factors, such as the eligibility of blood donation, blood donation program, and general facts about blnation. The difference in this case is significant at 0.05 level. However the knowledge about the blood is not corelated with blood donation experience, but only with sex(P<0.05). These results suggest that stable blood supply should be realized by securing new donors and by estsablishing of fdonor registration system. This is realized by the stir up the level of awareness and interest of blood program through strengthening public relations.
Blood Donors* ; Humans ; Public Relations ; Tissue Donors

The development of inexpensive high throughput methods to identify individual DNA sequences is important to the future growth of medical genetics. This has become increasingly apparent as psychiatric geneticists focus more attention on the molecular basis of complex multifactorial diseases at which most of psychiatric disease is estimated. Furthermore, candidate gene approaches used in identifying disease associated genes necessitate screening large sequence blocks for changes tracking with the disease state. Even after such genes are isolated, large scale mutational analysis will often be needed for risk assessment studies to define the likely medical consequences of carrying a mutated gene. This review provide basic knowledge of up-to-date technology, cDNA microarray which enables above mentioned various research themes.
Base Sequence ; DNA, Complementary* ; Genetics, Medical ; Mass Screening ; Oligonucleotide Array Sequence Analysis* ; Risk Assessment

No abstract available.
Korea* ; Tuberous Sclerosis*

The grading of astrocytoma has traditionally relied on histological assessment, but there are some differences in their parameters, application, and reproducibility. Recently, numerous studies have attempted to correlate biological aggresiveness with tumor proliferation index using new immunohistochemical methods. The purpose of this study is to correlate the histopathological grades of astrocytoma with the expression of Ki-67, PCNA, p53 protein and AgNORs. The paraffin sections of 41 consecutive cases of astrocytomas were examined. Histologically the tumors were graded as three groups under the St. Anne-Mayo system and showed 14 cases in grade II, 15 cases in grade III and 12 cases in grade IV (glioblastoma multiforme). As a result, the Ki-67 labelling index and p53 protein expression tended to increase with increasing grade of malignancy. But the univariate analysis showed that there was no significant difference between the tumor grades (p>0.05). The PCNA labelling index and number of AgNORs revealed striking differences between the grade II and grade III astrocytomas (p<0.05). We concluded that the PCNA labelling index and AgNORs counting are useful markers for differentiation between grade II and III astrocytomas.
Astrocytoma* ; Paraffin ; Proliferating Cell Nuclear Antigen* ; Strikes, Employee

PURPOSE: This study examined to explore factors influencing on employment stress of university students. METHODS: The data were collected by structured questionnaires to students who agreed to be the subjects of this study. And 230 cases were finally analyzed. T-test, one-way ANOVA, Pearson's correlation coefficients, and multiple regression were conducted for data analysis using SPSS/WIN 18.0. RESULTS: Significant differences revealed in age, department of major, residental type and school year on employment stress by general characteristics. Also, employment stress showed negative correlation with self-esteem, and satisfaction in major. Self-esteem and satisfaction in major, department of major were confirmed as a factors influencing on employment stress and accounted for 36% of the variance. CONCLUSION: Further studies that discover factors influencing on employment stress of university students are needed, and also practical programs are necessary to decrease employment stress of university students.
Employment* ; Humans ; Surveys and Questionnaires ; Statistics as Topic

We report two cases of recurrent extramarnmary Pagets disease after wide local excision. Both cases involved the scrotum and the penoserotal junction, respectively. On histopathological examination, we could observed many Paget cells confined to the epidermis and the hair follicle, but not invading the underlying dermis in both cases. There was no evidence of internal malignancy. Both cases were treated with wide local reexcision.
Dermis ; Epidermis ; Hair Follicle ; Paget Disease, Extramammary* ; Scrotum

No abstract available.
Aortic Stenosis, Supravalvular*

No abstract available.
Muscular Dystrophies*

We report an autopsy case of secondary hemochromatosis associated with multiple frequent blood transfusion for the treatment of aplastic anemia. A 23-year-old man had been diagnosed as having aplastic anemia at the age of 13. He received a whole blood transfusion, about 1280 ml, every month during the past 10 years. Recently he developed diabetes mellitus and a congestive heart failure. The autopsy revealed that multiple organs were affected by secondary hemochromatosis, including the liver, heart, pancreas, spleen, bone marrow, stomach, thyroid gland, adrenal glands, and testes. The lungs and liver showed gross and microscopic findings consistent with a congestive heart failure in addition to hemochromatosis. The details are presented. This is a case of rare secondary hemochromatosis occurring in a young man and presenting the classic histopathologic changes indistinguishable from those of primary hemochromatosis.
Adrenal Glands ; Anemia ; Anemia, Aplastic* ; Autopsy* ; Blood Transfusion ; Bone Marrow ; Diabetes Mellitus ; Heart ; Heart Failure ; Hemochromatosis* ; Humans ; Liver ; Lung ; Pancreas ; Spleen ; Stomach ; Testis ; Thyroid Gland ; Young Adult