1.Clinical Characteristics of Centenarians - A study on the Korean Centenarians.
Journal of the Korean Medical Association 2001;44(8):851-859
No abstract available.
Aged, 80 and over*
;
Humans
2.The Mitral Regurgitation in Patent Ductus Arteriosus(PDA).
Journal of the Korean Pediatric Society 1994;37(3):317-321
Mitral regurgitation (MR) was analyzed by Doppler echocardiography, preoperatively and postoperatively, in 59 patients with patent ductus arteriosus (PDA). The ratio of left atrial dimension and aortic root dimension (LAD/AOD) and the maximal velocity of the mitral valve (MVmax) were compared in pre, postop group. The degree of the regurgitation was given to the MR group. In preop MR group (13 of 59,22%), we compared the LAD/AOD by echo and the Qp/Qs by catheterization with non-MR group. The following results were obtained: 1) In preop MR group, about half of them had a grade 1 regurgitation, where as one fourth showed grade 2, remaining one fourth showed grade 3. The later were all changed to grade 2, postoperatively. The whiffle or mild MR (grade 1 or 2) shown preoperatively were slightly reduced in their degrees of regurgitation, but most were not disappeared and persisted to 7th postop day. 2) LAD/AOD and MVmax were significantly reduced at postop state of PDA. 3) In preop MR group (n=13), LAD/AOD was significantly increased. Qp/Qs was higher in MR grade 2 group (n=6). In conclusion, left atrial dilatation could be a factor causing mitral regurgitation in the PDA. The amount of the pulmonary blood flow also related to that. The size of the PDA itself, Rp/Rs and associated cardiac lesions were not related to the regurgitation.
Catheterization
;
Catheters
;
Dilatation
;
Ductus Arteriosus, Patent
;
Echocardiography, Doppler
;
Humans
;
Mitral Valve
;
Mitral Valve Insufficiency*
3.Clinical Characteristics of Postoperative Delirium after Urological Surgery.
Seong Yoon JUNG ; Ho Cheol CHOI ; Sung Hyup CHOI
Korean Journal of Urology 2001;42(2):218-222
PURPOSE: Delirium in the elderly is common in the postoperative period but there are only few reports on detailed studies of this condition. Number of urologic patients with postoperative delirium was increas ed in our hospital for recent 24 months. The clinical characteristics of patients with postoperative delirium was analyzed retrospectively. MATERIALS AND METHODS: We selected the patients with postoperative delirium from 1010 patients who had undergone urological surgery under general or spinal anesthesia in the period from Jan. 1997 to Dec. 1999. Diagnosis of postoperative delirium was established with Diagnostic and Statistical Manual of Mental Disorders(DAM-III-R) by psychiatric clinicians. Onset and recovery of symptoms, risk factors, previous psychiatric clinicians. Onset and recovery of symptoms, risk factors, previous psychiatric disorder, relationship with anesthesia, drugs, and surgical procedures, concomittant medical conditions, and complications were retrospectively reviewed. RESULTS: Postoperative delirium was observed in 13 patients (1.3%). All patients were male and mean age was 70.4 years (46-86 years). Surgical procedures included TURP(8 patients), cystectomy (3 patients), nephroureterectomy (1 patient), and bladder rupture repair (1 patient). Delirium became apparent between one day and two days after the operation (mean 32.2 hours) and lasted for up to 7 days (mean 53 hours). Several factors such as older age (>65 years), male patient, longterm medication, past history of CVA, memory impairment, hearing difficulty, traumatic brain contusion, and obsessive personality were thought to be risk factors of postoperative delirium. Treatment with Haloperidol(R) intramuscular injection (2.5-5mg, every 30 minutes, 2-4 times until symptom resolution was achieved) with or without Ativan(R) intravenous injection (2mg) were effective. Complete symptom recovery was seen in 92.3% (12/13) of patients. One patient (7.7%) with previous history of dementia had persistent memory disturbance and disorientation during follow-up periods. CONCLUSIONS: Generally, postoperative delirium is an acute transient confusional state without considerable sequeles. Treatment is sedation and prevention of inadvertent accident associated with confusional state. Urologic surgeon must be attentive to the development of this illness especially when high risk factors were present.
Aged
;
Anesthesia
;
Anesthesia, Spinal
;
Brain Injuries
;
Cystectomy
;
Delirium*
;
Dementia
;
Diagnosis
;
Follow-Up Studies
;
Hearing
;
Humans
;
Injections, Intramuscular
;
Injections, Intravenous
;
Male
;
Memory
;
Postoperative Period
;
Retrospective Studies
;
Risk Factors
;
Rupture
;
Urinary Bladder
4.Effect of nifedipine in acute episode of postoperative pulmonary hypertension and right heart failure.
Soon Ho CHOI ; Jong Bum CHOI ; Hyang Suk YOON
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(7):736-738
No abstract available.
Heart Failure*
;
Heart*
;
Hypertension, Pulmonary*
;
Nifedipine*
5.Characteristics of the Immortalized Human B-cells by Epstein-Barr Virus.
Ho Jong JEON ; Bong Nam CHOI ; Yoon Kyeong OH
Korean Journal of Pathology 1997;31(9):832-846
Human lymphoblastoid B-cell lines immortalized by Epstein-Barr virus (EBV) were established from peripheral blood of patients with acute myeloblastic and chronic lymphocytic leukemia and chronic fatigue syndrome. The sera of patients with acute myeloblastic and chronic lymphocytic leukemia did not show antibodies to Epstein-Barr viral capsid antigen (VCA), but serum of a patient with chronic fatigue syndrome disclosed antibodies to VCA (IgG, IgM), and EBNA was demonstrated in peripheral blood mononuclear cells by polymerase chain reaction. The established cell lines were mature B-cell phenotypes with polyclonal proliferation in early passage and no evidence for commitment to other lineages. The immortalized cells by EBV were designated as CSUP-1 and CSUP-2 (from acute myeloblastic leukemia, FAB classification M2 and M1), CSUP-3 (from chronic lymphocytic leukemia) and CSUP-4 (from a patient with chronic fatigue syndrome). The CSUP-1, 2, 3, and 4 grew in suspension forming clumps with a doubling time of 38 to 49 hours. Colony formation was not recognized in plate. By light and electron microscopic examination, the immortalized cells showed features of lymphoblastoid to plasmacytoid lymphocytes, and multinucleated giant cells. The lymphoblastoid cells showed scanty cytoplasm with poorly developed organelles. Immunophenotypic analyses of CUSP-1, 2, 3, and 4 with monoclonal antibodies by flow cytometry showed B-cell phenotype with polyclonal proliferation in early passage. Epstein-Barr virus nuclear antigen was confirmed in the extracted DNAs from immortalized cells by polymerase chain reaction. DNA analysis showed a normodiploid stemline with a DNA index of 1.12. The established cells were strongly reactive for CD10, CD30 (Ki-1) in early passage, and bcl-2 and c-myc onco-protein in early and late passage. Karyotypic analysis of CSUP-1, 2, 3 and 4 showed 46, XY or 46, XX. No tumorigenesis in heterotransplanted SCID mouse was recognized. This immortalized cells by EBV should be a valuable cell lines to study the pathogenesis of EBV-related malignant lymphoma.
Animals
;
Antibodies
;
Antibodies, Monoclonal
;
B-Lymphocytes*
;
Capsid
;
Carcinogenesis
;
Cell Line
;
Classification
;
Cytoplasm
;
DNA
;
Fatigue
;
Fatigue Syndrome, Chronic
;
Flow Cytometry
;
Giant Cells
;
Granulocyte Precursor Cells
;
Herpesvirus 4, Human*
;
Humans*
;
Leukemia, Lymphocytic, Chronic, B-Cell
;
Leukemia, Myeloid, Acute
;
Lymphocytes
;
Lymphoma
;
Mice
;
Mice, SCID
;
Organelles
;
Phenotype
;
Polymerase Chain Reaction
6.Linear Basal Cell Nevus: Report of One Case.
Wook Hwa BARK ; Ho Kyun CHOI ; Bong Chan YOON
Korean Journal of Dermatology 1970;8(2):59-62
The author observed one case of typical Linear bassal cell nevus who was 3 year old girl. Since birth, skin lesions reveal a linear band like nodules along the left lateral margin of nose, which are consists of pinhead sized, normal skin colored, pearly and translucent papules. Histopathologically, the preparations showed muItifocal irregular masses of basal type epithelial cells in continuity at pilosebaceous follicles and the cells were oval or spindle shaped and a peripheral palisade arrangement. But comedones and nevus cells were not identified. Diagnosis confirmed by clinical appearance, histopathologically and other clinical study. There were marked improvement by the locaI application of 2% 5-Fluorouracil solution.
Child, Preschool
;
Diagnosis
;
Epithelial Cells
;
Female
;
Fluorouracil
;
Humans
;
Nevus*
;
Nose
;
Parturition
;
Skin
7.Primary malignant tumors of the ethmoid sinus.
Seung Ho LEE ; Jong Ouck CHOI ; Kwang Yoon JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):920-924
No abstract available.
Ethmoid Sinus*
8.THE VARIOUS ROLE OF LOCAL INJECTION OF BOTULINUM A EXOTOXIN.
Yoon Ho LEE ; Hee Chan CHOI ; Jin Joo HONG
Journal of the Korean Society of Aesthetic Plastic Surgery 1999;5(2):377-389
Botulium toxin A has been used therapeutically in humans for over 20 years for a variety of medical indications. Some wrinkle and unsightly facial expressions are due to hyperkinetic muscle. For the past year, the author has injected it for variant purpose, so we describe the our experience with the variant extended use of the toxin including correction for just dynamic wrinkle, used with subperiosteal face lifting or peeling, post-traumatic twitching, and facial paralysis and relevant anatomy are discussed. Also we have another concept about muscle anatomy which have superficial and deep portion. The superficial portion is for harmonious action with SMAS during facial expression, which is also related to fine wrinkle, and the deep portion play role gross movement. Botulium toxin is safe and effective in varient field without complication. Its use is associated with a high degree of patient and physician satisfaction.
Exotoxins*
;
Facial Expression
;
Facial Paralysis
;
Humans
;
Rhytidoplasty
9.Effect of oxygenation of cardioplegic solution on electrical stability and postischemic recovery of cardiac function after ischemic arrest in isolated rat heart(I).
Jae Do YOON ; Jong Bum CHOI ; Soon Ho CHOI ; Bong Kyu CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(2):125-130
No abstract available.
Animals
;
Cardioplegic Solutions*
;
Oxygen*
;
Rats*
10.Significance of Postoperative Peritoneal Drainage and Peritoneal Dialys is in Infants with congenital Heart Disease Who Underwent Open Heart Srugery.
Ji Hwan CHOI ; Jae Hwa OH ; Hyang Suk YOON ; Jong Bum CHOI ; Soon Ho CHOI
Journal of the Korean Pediatric Society 2000;43(9):1207-1212
PURPOSE: We reviewed 5 years worth of experience with peritoneal drainage and dialysis in infants who underwent open heart surgery. The aim of this study was to investigate the effect of peritoneal drainage and peritoneal dialysis on fluid balance and several parameters of intensive care. METHODS: Six(10%) of 60 consecutive infants who underwent open heart surgery required peritoneal dialysis during peritoneal drainage. Simple peritoneal drainage was performed in the remaining 54 infants. The silicone rubber peritoneal dialysis catheter was inserted into the center of abdominal cavity just after operation, and subsequent peritoneal drainage was maintained during intensive care. RESULTS: Mean age of the study group was 0.48+/-0.21 years(M: F=32: 28). Early postoperative mortality amang the infants with congenital heart disease was 1.6%. Total amount of output was 7.0+/-2.28mL/kg/hr, urine output 5.14+/-2.9lmL/kg/hr, pleural fluid 0.80+/-0.5lmL/kg/hr, and peritoneal fluid 1.20+/-0.90mL/kg/hr. The ratio of output to intake(O/I) was 1.06. None of the complications required early termination of peritoneal drainage or peritoneal dialysis. Hemodynamics and pulmonary function were maintained steadily during postoperative intensive care. CONCLUSION: The early institution of peritoneal drainage and peritoneal dialysis in infants with congenital heart disease after cardiac operations not only removes fluid, thus easing fluid restriction, but may also improve cardiopulmonary function.
Abdominal Cavity
;
Ascitic Fluid
;
Catheters
;
Dialysis
;
Drainage*
;
Heart Defects, Congenital*
;
Heart*
;
Hemodynamics
;
Humans
;
Infant*
;
Critical Care
;
Mortality
;
Peritoneal Dialysis
;
Silicone Elastomers
;
Thoracic Surgery
;
Water-Electrolyte Balance