1.Death Associate with Sweet's Syndrome.
Zhe LI ; Pil Gyu HWANG ; Yoon Seong LEE ; Jung Bin LEE ; Soong Deok LEE
Korean Journal of Legal Medicine 2003;27(2):82-86
Sweet's syndrome was originally described as an "acute febrile neutrophilic dermatosis". Sweet's syndrome presents in three clinically settings: (1) classical or idiopathic Sweet's syndrome, (2) malignancyassociated or paraneoplastic Sweet's syndrome, (3) drug-induced Sweet's syndrome. Sweet's syndrome is known to respond well to systemic corticosteroids, and mortal case associated without any other predisposing factors is hardly found. Twenty-nine year old male was transferred from local clinic with the chief complaint of recurrent thrombophlebitis which occurred 10 days ago after IV treatment of antibiotics for burn. The symptom did not get well with conventional treatment for the thrombophlebitis such as antibiotics or drainage. After several days of pyrexia, the patient died suddenly. Grossly abnormal findings including pulmonary thrombus which could explain sudden death were not found. Disseminated intravascular microthrombi was the most peculiar finding. It was prominent in small sized vein, and lung was the most severely affected. Heart and liver were also involved. Large thrombi within deep vein of the legs were also noted. Minor collections of inflammatory cells, even apart from the main lesion, were noted in skin adnexa or small vessles within aorta wall. No tumorous area was found. The disseminated intravascular coagulation, which was associated with vasculitis was thought to be the direct cause of death. Several points about the Sweet's syndrome including the unusualness of this case were discussed.
Adrenal Cortex Hormones
;
Anti-Bacterial Agents
;
Aorta
;
Burns
;
Causality
;
Cause of Death
;
Death, Sudden
;
Disseminated Intravascular Coagulation
;
Drainage
;
Fever
;
Heart
;
Humans
;
Leg
;
Liver
;
Lung
;
Male
;
Neutrophils
;
Skin
;
Sweet Syndrome*
;
Thrombophlebitis
;
Thrombosis
;
Vasculitis
;
Veins
2.Dental management of patients with X-linked hypophosphatemia.
Bin Na LEE ; Hye Yoon JUNG ; Hoon Sang CHANG ; Yun Chan HWANG ; Won Mann OH
Restorative Dentistry & Endodontics 2017;42(2):146-151
X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium phosphate. Its dental features include spontaneous dental abscesses that occur in the absence of trauma or dental caries. The aim of this case report was to describe the dental problems of XLH patients and to evaluate limitations in their treatment. A 14 year old male and a 38 year old female with XLH were referred to the Department of Conservative Dentistry for endodontic treatment. The dental findings were periapical abscesses without obvious trauma or caries. Conservative endodontic treatment was performed in teeth with pulp necrosis and abscess. In case 1, the treated teeth showed improvements in bone healing, without clinical symptoms. However, in case 2, the implants and the treated tooth showed hypermobility, and the final restoration was therefore postponed. Early diagnosis, periodic examinations, and communication with the patient's pediatrician are important in the dental management of patients with XLH.
Abscess
;
Calcium
;
Dental Caries
;
Dental Pulp Necrosis
;
Dentistry
;
Early Diagnosis
;
Familial Hypophosphatemic Rickets*
;
Female
;
Humans
;
Hypophosphatemia
;
Male
;
Metabolic Diseases
;
Periapical Abscess
;
Potassium
;
Tooth
3.Adenosquamous Carcinoma of the Pancreas: A Case Report.
Jun Hyuk SON ; Sang Hyub LEE ; Byung Hyo CHA ; Jin Hyeok HWANG ; Yun Bin LEE ; Yoo Seok YOON ; So Yeon KIM ; Hae Ryoung KIM
Korean Journal of Gastrointestinal Endoscopy 2011;42(6):433-436
Adenosquamous carcinoma of the pancreas is a rare tumor, which is difficult to diagnose. A 65-year-old man was admitted complaining of abdominal pain. Abdominal computed tomography (CT) demonstrated a cystic mass in the pancreatic body. Endoscopic ultrasound (EUS) showed an approximate 1.0 cm-sized hypoechoic cystic mass with a solid portion in the pancreatic body and narrowing of the main pancreatic duct. Under the impression of acute pancreatitis with a pseudocyst diagnosis, medical therapy including pancreatic stent insertion was administered to the patient for 4 weeks. A distal pancreatectomy was performed with the suspicion of pancreatic cancer due to the remaining mass on a follow-up CT scan, and the tumor was histopathologically diagnosed as stage I (TNM classification) adenosquamous carcinoma of the pancreatic body. The patient was discharged without any problems and has been on follow-up without recurrence. We report a case of adenosquamous carcinoma of the pancreas that was diagnosed relatively early with the help of EUS.
Abdominal Pain
;
Aged
;
Carcinoma, Adenosquamous
;
Follow-Up Studies
;
Humans
;
Pancreas
;
Pancreatectomy
;
Pancreatic Ducts
;
Pancreatic Neoplasms
;
Pancreatitis
;
Recurrence
;
Stents
4.Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children.
Eung Bin LEE ; Yun Young LEE ; Jae Min LEE ; Su Min SON ; Su Kyeong HWANG ; Soonhak KWON ; Sae Yoon KIM
Korean Journal of Pediatrics 2016;59(6):271-275
PURPOSE: A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. METHODS: The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups. RESULTS: Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment: 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05). CONCLUSION: This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-wave abnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-wave abnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.
Child*
;
Fever
;
Guillain-Barre Syndrome*
;
H-Reflex
;
Humans
;
Immunoglobulins
;
Incidence
;
Prevalence
;
Prognosis
;
Reflex, Abnormal
;
Retrospective Studies
5.A Case of Xanthogranulomatous Pyelonephritis in Children.
Sung Bin YIM ; Chil Kyu KWON ; Jae Hyun LEE ; Jong Soon SHIN ; Jae Sung YIM ; Moon Ha HWANG ; Yool Ro YOON
Korean Journal of Urology 1997;38(10):1117-1120
Xanthogranulomatous pyelonephritis is an uncommon form of chronic pyelonephritis occurring usually in middle-aged women. This disease is characterized by destruction of the renal parenchyma which is then replaced by granulomatous tissue containing lipid-laden macrophages (foam cells). But this disease is hard to diagnose preoperatively since it resembles renal abscess, renal cell carcinoma, renal tuberculosis and so forth. Xanthogranulomatous pyelonephritis in children is rare. We report a case in a 30 month-old boy.
Abscess
;
Carcinoma, Renal Cell
;
Child*
;
Child, Preschool
;
Female
;
Humans
;
Macrophages
;
Male
;
Pyelonephritis
;
Pyelonephritis, Xanthogranulomatous*
;
Tuberculosis, Renal
6.Asymptomatic Common Iliac Artery Stenosis as a Cause of Renal Allograft Dysfunction and Uncontrolled Hypertension.
Sang Bin LEE ; Hyeon Jeong KANG ; Hee Jun KANG ; Sun Hee JANG ; Hyeon Seok HWANG ; Yoon Kyung CHANG ; Suk Young KIM ; Yu Ah HONG
The Journal of the Korean Society for Transplantation 2016;30(3):133-137
Occlusive disease of the iliac segment, proximal to the transplant artery (prox-TRAS), in kidney transplant recipients is a rare complication. Prox-TRAS, located in the common iliac artery, is extremely rare in these patients. Herein, we present an interesting case of a common iliac artery stenosis that manifested as decreased allograft function and uncontrolled blood pressure without other typical clinical symptoms. The patient was successfully treated with percutaneous luminal angioplasty and stent insertion.
Allografts*
;
Angioplasty
;
Arteries
;
Blood Pressure
;
Constriction, Pathologic*
;
Humans
;
Hypertension*
;
Iliac Artery*
;
Kidney
;
Kidney Transplantation
;
Phenobarbital
;
Stents
;
Transplant Recipients
7.Three Cases of Urachal Anomalies.
Bo Hyun SHIN ; Sung Bin YIM ; Kwang Jun YOON ; Jae Hyun LEE ; Jong Soon SHIN ; Jae Sung LIM ; Moon Ha HWANG ; Chong Koo SUL
Korean Journal of Urology 1997;38(9):1013-1016
The Urachus lies between the peritoneum and transversalis fascia and extends from the anterior dome of the bladder toward the umbilicus. During the 4th and 5th months of gestation, the urachus narrows to a small-calibered epitherial tube. During fetal development, as the bladder descends into the pelvis, its apical portion narrows progressively into a fibromuscular strand of urachus. Recently, we reviewed three cases of urachal anomalies with literatures.
Fascia
;
Fetal Development
;
Pelvis
;
Peritoneum
;
Pregnancy
;
Umbilicus
;
Urachus
;
Urinary Bladder
8.Change of In-Shoe Plantar Pressure According to Types of Shoes (Flat Shoes, Running Shoes, and High Heels)
Yun Jae CHO ; Dong-Woo LEE ; Hyuck Soo SHIN ; Yoon Bin HWANG ; Dong Oh LEE ; Dae-Yoo KIM ; Dong Yeon LEE
Clinics in Orthopedic Surgery 2022;14(2):281-288
Background:
The type of footwear is one of several factors that affect foot pressure. Despite its usefulness in identifying pathology and preventing and treating foot-related diseases, the type of shoes has been investigated and compared in only a few studies. This study aimed to investigate differences in plantar pressure, induced by flat, running, and high-heeled shoes in healthy, young women.
Methods:
A total of 27 healthy women (27 feet) with a mean age of 21.5 ± 2.03 years were included in this study. Based on demographic data, radiologic measurements, clinical scores, temporal gait parameters, and kinematic parameters of gait, we confirmed the participants had normal feet. Then, pedobarographic data were measured by dividing each foot into seven regions to compare the three types of shoes. Peak plantar pressure and pressure-time integral were calculated using the Pedar-X system. The one-way analysis of variance and the Kruskal-Wallis test with Mann Whitney U-test were used for statistical analyses.
Results:
Regarding the 7 regions of the foot, flat shoes resulted in a significantly higher pressure than running shoes in the hallux and lesser toes and the highest pressure in the metatarsal head (MTH) 3–5 and the hindfoot. In contrast, in the MTH 1 and MTH 2 regions, the high-heeled shoes had the highest measured pressure, followed by the flat shoes. Lastly, there was no high pressure in running shoes in any region except for the midfoot compared to the other shoes.
Conclusions
It can be inferred from our findings that flat and high-heeled shoes can generate a considerable burden on specific parts of the foot, which will aid in choosing appropriate shoes. Also, wearing running shoes places less burden on the overall foot.
9.Oral manifestation and root canal therapy of the patient with mucopolysaccharidosis
Ji Hye YOON ; Hyo Il LEE ; Ji Hyun JANG ; Sung Hyeon CHOI ; Hoon Sang CHANG ; Yun Chan HWANG ; In Nam HWANG ; Bin Na LEE ; Won Mann OH
Restorative Dentistry & Endodontics 2019;44(2):e14-
Mucopolysaccharidosis (MPS) is an inherited metabolic disorder caused by a deficiency in enzymes that participate in the degradation of glycosaminoglycans (GAGs) such as heparin sulfate and dermatan sulfate. Left untreated, patients show progressive mental and physical deterioration due to deposition of GAGs in organs. Death often occurs due to cardiac or respiratory failure before patients reach their early twenties. MPS has several oral and dental manifestations. An enlarged head, short neck, and open mouth associated with a large tongue are major characteristics of MPS patients. Dental complications can be severe, including unerupted dentition, dentigerous cyst-like follicles, malocclusions, condylar defects, and gingival hyperplasia. A 21-year-old female patient with MPS was described in this article, with special emphasis on oral manifestations and dental treatment.
Dental Pulp Cavity
;
Dentition
;
Dermatan Sulfate
;
Female
;
Gingival Hyperplasia
;
Glycosaminoglycans
;
Head
;
Heparin
;
Humans
;
Malocclusion
;
Mouth
;
Mucopolysaccharidoses
;
Neck
;
Oral Manifestations
;
Respiratory Insufficiency
;
Root Canal Therapy
;
Tongue
;
Young Adult
10.Novel Method Measuring Conjunctival Microvascular Blood Flow Velocity by Zoom-lens, Ultra-high-speed Camera Attached Slit-lamp Biomicroscope
Hyo Sin KIM ; Da Ran KIM ; Young Chae YOON ; Soon Won YANG ; Young Sik YOO ; Woong Joo WHANG ; Yong-Soo BYUN ; Hyung Bin HWANG ; Kyung Sun NA ; Hyun Soo LEE ; So Hyang CHUNG ; Eun Chul KIM ; Yang Kyung CHO ; Hyun Seung KIM ; Ho Sik HWANG
Journal of the Korean Ophthalmological Society 2023;64(11):1001-1008
Purpose:
To introduce an intuitive method for measuring conjunctival microvascular blood flow velocity by imaging bulbar conjunctival microvessels using a slit-lamp biomicroscope equipped with a zoom lens and an ultra-high-speed camera.
Methods:
After obtaining consent from 10 patients (1 male, 9 females) who visited Yeouido St. Mary’s Hospital from August 21, 2020, to June 12, 2021, the patients were examined under a slit lamp microscope equipped with an ultra-high-speed camera and zoom lens. The blood flow in the conjunctival microvessels was photographed. The captured images were analyzed with ImageJ software to measure the blood flow velocity in the conjunctival microvessels, and we investigated whether the blood flow velocity correlated with the vessel diameter and age.
Results:
The median age of the subjects was 49.0 years. The mean conjunctival blood flow velocity in 53 microvessels was 0.786 ± 0.468 mm/s. The median conjunctival microvascular diameter was 7.06 μm (interquartile range 5.84 to 9.23 μm). The conjunctival microvascular diameter and blood flow velocity were not significantly correlated (Spearman’s p = 0.177), and the subjects’ age and conjunctival microvascular blood flow velocity were also not correlated (Spearman’s p = 0.669).
Conclusions
In this study, the blood flow velocity in the bulbar conjunctival microvessels could be measured easily by means of image analysis using a slit-lamp microscope equipped with an ultra-high-speed camera with a zoom lens.