1.Acute Myocarditis Complicated by Permanent Complete AV Block Associated with Salmonella Group B Gastroenteritis.
Yoon Ah PARK ; Young Hwue KIM ; In Sook PARK
Korean Circulation Journal 1995;25(3):698-703
Acute infectious myocarditis in children can be caused by many pathogens, including bacteria, viruses, fungi and protozoa. Patients may be asymptomatic or may have 'flu-like symptoms' to life-theratening arrhythmias or sudden death. We herein report a case of acute myocarditis complicated by complets and permanent AV block, associated with Salmonella group B gastroenteritis in a previously healthy 5-year-old boy. Presenting symptoms were dyspnea, cyanosis, vomiting, and diarrhea. Electrocardiography on admission showed very slow ventricular escape rhythm at 37 beats/minute. He was treated with antibiotics, inotropic agents, ventilatory support, and transvenous temporary pacemaker. Ten days later, permanent dual chamber pacemaker was implanted. All three consecutive stool cultures done after admission grew Salmonella group B. His ventricular function recovered rapidly and completely and he became fully active 2 months after the onset. However, his conduction system was totally destroyed and at last follw up evaluation 2 years after the onset, he is still totally dependent on the pacemaker without any escape rhythm.
Anti-Bacterial Agents
;
Arrhythmias, Cardiac
;
Atrioventricular Block*
;
Bacteria
;
Child
;
Child, Preschool
;
Cyanosis
;
Death, Sudden
;
Diarrhea
;
Dyspnea
;
Electrocardiography
;
Fungi
;
Gastroenteritis*
;
Humans
;
Male
;
Myocarditis*
;
Salmonella*
;
United Nations
;
Ventricular Function
;
Vomiting
2.Tetanus and masticatory muscle spasm.
Jong Ho LEE ; Jung Jae JEONG ; Jun Ah PARK ; Jeong Han YOON
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(3):379-384
No abstract available.
Masticatory Muscles*
;
Spasm*
;
Tetanus*
3.Risk Factor of Left Atrial Thrombi after Valve Replacement.
Yoon Nyun KIM ; Young Sung SONG ; Sung Rae CHO ; Kyung Ah PARK ; Sae Young CHOI
Korean Circulation Journal 1993;23(5):684-691
BACKGROUND: Thromboembolism is the major complication in patients with the insertion of cardiac prosthetic valves. The purpose of this study is evaluate the risk factors about the formation of left atrial thrombi after cardiac valve replacement. METHOD: Transesophageal(TEE) and transthoracic echocardiography(TTE) were done to evaluate postoperative cardiac condition in 98 patients with cardiac prosthetic valves from Jan. 1991 to Oct 1991. Several clinical and echocardiographic parameters were analyzied to evaluate the relationship with the formation of left atrial thrombi. RESULT: In univariate analysis, important factors related to the formation of left atrial thrombi are type of operation (p=0.027), postoperative left ventricular function(p=0.003), preoperative(p=0.037) and postoperative systolic ventricular size(p=0.024). However, in multivariate analysis postoperative left ventricular size(p=0.017), presence of previous thrombi(p=0.014), preoperative left atrial size(p=0.014) and postoperative left atrial size(p=0.014) are significant factors. CONCLUSION: Patients with high risk and low risk for the formation of left atrial thrombi after valve replacement can be identified by readily available clinical and echocardiographic variables.
Echocardiography
;
Heart Valves
;
Humans
;
Multivariate Analysis
;
Risk Factors*
;
Thromboembolism
4.New three-dimensional cephalometric analyses among adults with a skeletal Class I pattern and normal occlusion.
Mohamed BAYOME ; Jae Hyun PARK ; Yoon Ah KOOK
The Korean Journal of Orthodontics 2013;43(2):62-73
OBJECTIVE: The purpose of this study was to assess new three-dimensional (3D) cephalometric variables, and to evaluate the relationships among skeletal and dentoalveolar variables through 3D cephalometric analysis. METHODS: Cone-beam computed tomography (CBCT) scans were acquired from 38 young adults (18 men and 20 women; 22.6 +/- 3.2 years) with normal occlusion. Thirty-five landmarks were digitized on the 3D-rendered views. Several measurements were obtained for selected landmarks. Correlations among different variables were calculated by means of Pearson's correlation coefficient values. RESULTS: The body of the mandible had a longer curve length in men (102.3 +/- 4.4 mm) than in women (94.5 +/- 4.7 mm) (p < 0.001), but there was no significant difference in the maxillary basal curve length. Men had significantly larger facial dimensions, whereas women had a larger gonial angle (117.0 +/- 4.0 vs. 113.8 +/- 3.3; p < 0.001). Strong-to-moderate correlation values were found among the vertical and transverse variables (r = 0.71 to 0.51). CONCLUSIONS: The normative values of new 3D cephalometric parameters, including the maxillary and mandibular curve length, were obtained. Strong-to-moderate correlation values were found among several vertical and transverse variables through 3D cephalometric analysis. This method of cephalometric analyses can be useful in diagnosis and treatment planning for patients with dentofacial deformities.
Adult
;
Cone-Beam Computed Tomography
;
Dentofacial Deformities
;
Female
;
Humans
;
Male
;
Mandible
;
Young Adult
5.Molecular Mechanism of TNF-alpha and MMP-9 Production in Response to HIV-1 Core Antigen p24 in Human Monocytie THP-1 Cells.
Soon Ah SHIN ; Yoon Jung BAE ; Hyun Joo LEE ; Hae Kyung PARK ; Young Hae CHONG
Journal of Bacteriology and Virology 2001;31(4):369-377
No abstract available.
HIV-1*
;
Humans*
;
Tumor Necrosis Factor-alpha*
6.Changes of alpha- and beta-calcitonin gene-related peptide expression in rat spinal cord after spinal cord transection, ventral rhizotomy or dorsal rhizotomy.
Ho YOON ; Won Taek LEE ; Kyung Ah PARK
Korean Journal of Anatomy 1999;32(1):53-63
Calcitonin gene-related peptide (CGRP), a well-known neuropeptide in primary sensory neurons carrying noci-ceptive information, includes two different peptides of similar structure, the alpha- and beta-CGRP. The distribution of these two peptides in the central nervous system is known to be similar and no functional differences have been reported. The aim of this study is to investigated the changes of alpha- and beta-CGRP expression following efferent or afferent disconnection of anterior horn cells in the rat spinal cord. One week after ventral rhizotomy (left L4-6), dorsal rhizotomy (left L4-6) or spinal cord transection (at lower thoracic level), the animals were sacrified and the L5 segments of the spinal cord were excised to perform immunohistochemistry and in situ hybridization histochemistry. In the control group, 4.45+/-1.51 anterior horn cells showed CGRP immunoreactivity per tissue section in one side. After ventral rhizotomy, the number of CGRP immunoreactive neurons increased to 9.12+/-2.52 at the ipsilateral ventral horn. After dorsal rhizotomy, CGRP immunoreactive neurons increased to 7.29+/-3.69 at the ipsilateral ventral horn and 6.26+/-1.53 at the contralateral ventral horn. In cases of spinal cord transection, almost all the anterior horn cells lost CGRP immunoreactivity in both sides. Neurons expressing alpha- or beta-CGRP mRNA could be distinguished by in situ hybridization histochemistry. In the control group, anterior horn cells expressing alpha-CGRP mRNA numbered 4.16+/-1.32 per section and beta-CGRP cells numbered 5.50+/-1.38. After ventral rhizotomy, the number of cells expressing alpha-CGRP mRNA increased to 10.07+/-2.86 in the ipsilateral side without any changes in beta-CGRP mRNA expression. After dorsal rhizotomy, no significant changes in alpha-CGRP mRNA expression were detected, but the number of cells expressing beta-CGRP mRNA increased to 7.45+/-2.04 in the ipsilateral side and to 7.02+/-1.38 in the contralateral side. In cases of spinal cord transection, the anterior horn cells lost alpha- and beta-CGRP mRNA signals almost completely in both sides. These results showed that alpha-CGRP expression increased in axotomized anterior horn cells of the spinal cord, and that beta-CGRP expression increased in anterior horn cells which had lost their afferent input through the primary sensory neurons. These findings provide evidence showing the functional difference of the two peptides in anterior horn cells of the spinal cord.
Animals
;
Anterior Horn Cells
;
Calcitonin Gene-Related Peptide
;
Central Nervous System
;
Horns
;
Immunohistochemistry
;
In Situ Hybridization
;
Neurons
;
Neuropeptides
;
Peptides
;
Rats*
;
Rhizotomy*
;
RNA, Messenger
;
Sensory Receptor Cells
;
Spinal Cord Injuries*
;
Spinal Cord*
7.Effects of intravesical capsaicin on the substance P- and CGRP-immunoreactive terminals of the rat spinal dorsal horn.
Ho YOON ; Won Taek LEE ; Kyung Ah PARK
Korean Journal of Anatomy 1999;32(4):497-507
Visceral afferent nerve fibers containing substance P or calcitonin gene-related peptide (CGRP) are distributed in the bladder wall, and are known to be stimulated by and then desensitized by capsaicin. Recently, there have been some reports on the effectiveness of intravesical capsaicin administration for the treatment of hypersensitive lower urinary tract disorder or neurogenic bladder. In this study, the effects of intravesical capsaicin on the substance P or CGRP immunoreactivities in the spinal dorsal horn were investigated and the mechanism of capsaicin treatment for bladder disorders was revealed. After intravesical administration of capsaicin, the substance P and CGRP immunoreactive areas were measured at the dorsal horn of L4 and S1 spinal cord. Before capsaicin treatment, the substance P immuno- reactive area was 2.61+/-0.78 x 105 mm2 in L4 and 1.66+/-0.49 x 105 mm2 in S1. The substance P immunoreactivity was markedly reduced 1~2 weeks after capsaicin treatment in both L4 and S1 spinal cord. The CGRP immunoreactive area was 1.74+/-0.52 x 105 mm2 in L4 and 1.14+/-0.69 x 105 mm2 in S1, but was not reduced after capsaicin treatment. Therefore, capsaicin administered intravesically desensitizes nerve fibers containing substance P and consequently suppresses pain and voiding reflex.
Administration, Intravesical
;
Animals
;
Calcitonin Gene-Related Peptide
;
Capsaicin*
;
Horns*
;
Nerve Fibers
;
Rats*
;
Reflex
;
Spinal Cord
;
Substance P
;
Urinary Bladder
;
Urinary Bladder, Neurogenic
;
Urinary Tract
;
Visceral Afferents
8.Coronary CT AngiographyBased Assessment of Coronary in-Stent Restenosis:A Journey through Past and Present Trends
Yoon Seong LEE ; Eun-Ah PARK ; Whal LEE
Journal of the Korean Society of Radiology 2024;85(2):258-269
Treatment of patients with coronary artery disease commonly involves the use of balloon-expandable stent placements, currently recognized as the most prevalent approach for coronary artery revascularization. Nevertheless, the occurrence of restenosis remains a significant complication following percutaneous coronary interventions. The diagnostic role of coronary CT angiography (CCTA) in detecting stent restenosis has limitations primarily attributable to challenges in accurately discerning the lumen, due to issues such as blooming and motion artifacts. As a result, many cases often necessitate a transition to conventional coronary angiography. However, recent advancements in CT technology have led to notable improvements in both sensitivity and specificity, underscoring the growing significance of CCTA as a diagnostic tool. The consistent reporting of high negative predictive value is particularly noteworthy. This review aims to explore the historical context, current status, and recent trends in diagnosing coronary artery stent restenosis using CCTA.
9.Coronary CT AngiographyBased Assessment of Coronary in-Stent Restenosis:A Journey through Past and Present Trends
Yoon Seong LEE ; Eun-Ah PARK ; Whal LEE
Journal of the Korean Society of Radiology 2024;85(2):258-269
Treatment of patients with coronary artery disease commonly involves the use of balloon-expandable stent placements, currently recognized as the most prevalent approach for coronary artery revascularization. Nevertheless, the occurrence of restenosis remains a significant complication following percutaneous coronary interventions. The diagnostic role of coronary CT angiography (CCTA) in detecting stent restenosis has limitations primarily attributable to challenges in accurately discerning the lumen, due to issues such as blooming and motion artifacts. As a result, many cases often necessitate a transition to conventional coronary angiography. However, recent advancements in CT technology have led to notable improvements in both sensitivity and specificity, underscoring the growing significance of CCTA as a diagnostic tool. The consistent reporting of high negative predictive value is particularly noteworthy. This review aims to explore the historical context, current status, and recent trends in diagnosing coronary artery stent restenosis using CCTA.
10.Coronary CT AngiographyBased Assessment of Coronary in-Stent Restenosis:A Journey through Past and Present Trends
Yoon Seong LEE ; Eun-Ah PARK ; Whal LEE
Journal of the Korean Society of Radiology 2024;85(2):258-269
Treatment of patients with coronary artery disease commonly involves the use of balloon-expandable stent placements, currently recognized as the most prevalent approach for coronary artery revascularization. Nevertheless, the occurrence of restenosis remains a significant complication following percutaneous coronary interventions. The diagnostic role of coronary CT angiography (CCTA) in detecting stent restenosis has limitations primarily attributable to challenges in accurately discerning the lumen, due to issues such as blooming and motion artifacts. As a result, many cases often necessitate a transition to conventional coronary angiography. However, recent advancements in CT technology have led to notable improvements in both sensitivity and specificity, underscoring the growing significance of CCTA as a diagnostic tool. The consistent reporting of high negative predictive value is particularly noteworthy. This review aims to explore the historical context, current status, and recent trends in diagnosing coronary artery stent restenosis using CCTA.