We sudied, with echocardiography as a main tool, the natural processes of 211 patients with uncomplicated ventricular septal defect (VSD) (incidence, 5.33 per 1,000 live births); 146 (69.2%) had a perimenbranous VSD and 32 (15.2%) had a subarterial, 25 (11.8%) had a muscular type of VSD. Cumulative rate of spontaneous closure was 26.1%. In the closure processes, about three-fourth of perimembranous VSD showed a partial closure or tunnel formation by changes of septal leaflet of the tricuspid valve, remaining one-fourth showed a "functional" complete closure. Four of 58 neonates had a partially closed-perimembranous VSD. Rates of infundibular stenosis and Eisenmenger syndrome were 6.6% and 1.4% respectively. Aortic prolapse with insufficiency was detected in 6 patients who were over 6 years of age. Surgical closure was required in 27.5% of all studied patients and in 12% of infants (14 of 177). No natural deaths were observed during the study-periods of recent 3 years. But, 3 of 58 (5.2%) were dead postoperativel (two were early, one late). Doppler color flow mapping is a valuble aid in the diagnosis of VSD and may be on reason for the observed increase in the incidence of VSDs.
Constriction, Pathologic ; Diagnosis ; Echocardiography* ; Eisenmenger Complex ; Heart Septal Defects, Ventricular* ; Humans ; Incidence ; Infant ; Infant, Newborn ; Prolapse ; Tricuspid Valve

Ichthyosis hystrix is a localized variant of Bullous Congenital Ichthyosiform Erythroderma by Broq, and also, localized form of Epidermolytic hyperkeratosis according to Frost and Van Scott's classification of ichthyosi-form dermatoses. Clinically it is generally considered to be widespread systematized epidermal nevus, and demonstrating an autosomal dominant pattem of inheritance, and characterized by verrucous scale at or shortly after birth with particular involve- ment of flexural areas. A case of 21 year old girl with ichthyosis hystrix was reported, The skin lesion showed multiple rice to pea sized linear verrucous papules on left forearm, neck, axilla and upper chest. The skin biopsy was done, the finding shows remarked laminated hyperkeratosis, acanthosis, papillomatosis, and vacuoliization on malpighian layer. Diagnosis was confirmed by clinicaI apperance and histopathologicaI finding. The method of treatment is 0. 05% Vitamin A acid ointment application and show marked improvement.
Axilla ; Biopsy ; Classification ; Diagnosis ; Female ; Forearm ; Humans ; Hyperkeratosis, Epidermolytic ; Ichthyosis* ; Neck ; Nevus ; Papilloma ; Parturition ; Peas ; Porcupines* ; Skin ; Skin Diseases ; Thorax ; Tretinoin* ; Vitamin A* ; Vitamins* ; Wills ; Young Adult

Colonic sarcomatoid carcinomas are known to be extremely rare tumors, with only 22 cases reported either as sarcomatoid carcinomas or carcinosarcomas in the literature. The known characteristics are rapid growth, a high recurrence rate, and an extremely poor prognosis. Herein we report a case of a patient who had a sarcomatoid carcinoma of the sigmoid colon and died only 22 days after surgery due to rapid tumor growth.
Carcinosarcoma ; Colon ; Colon, Sigmoid ; Humans ; Prognosis ; Recurrence

BACKGROUND: Nitric oxide(NO), a multifunctional mediator, is known as a endothelium-derived relaxing factor, a neurotransmitter, and a killer molecule formed by activated immune cells and participates in tissue destruction via apoptosis. In the skin, an increase in apoptotic cells has been desribed in the epidermis in various lichenoid diseases, in response, to ultraviolet radiation, and in neoplasia. OBJECTIVE: The purpose of this study is to investigate whether a positive correlation occurs between iNOS(inducible nitric oxide synthase) expression and apoptosis index in psoriasis vulgaris(PV), lichen planus(LP), and Bowen's disease(BD). METHODS: TUNEL staining and immunohistochemical staining with anti-iNOS antibody were done in paraffin-embedded tissue sections of 4 cases of PV, 4 cases of LP, and 2 cases of BD.
Apoptosis* ; Bowen's Disease* ; Endothelium-Dependent Relaxing Factors ; Epidermis ; In Situ Nick-End Labeling ; Lichen Planus* ; Lichens* ; Neurotransmitter Agents ; Nitric Oxide ; Psoriasis* ; Skin

No abstract available.
Korea*

No abstract available.
Echocardiography, Doppler* ; Heart Defects, Congenital*

This study was performed to investigate nurses' perception for nutrition education. The subjects of this study were 197 nurses and 94 nursing assistants working at hospitals in the Kyung-nam area. The survey was conducted by using a self-administered questionnaire in November, 2001. The results were as follows : Sixty-seven point seven percent of the subjects were nurse, 32.3% were nursing assistant. Average age of subjects was 26.9 years old, average nursing experience was 5.7 years, and 70.7% of the subjects graduated from a junior college. The average nutrition knowledge score was 14.3+/-2.5 out of possible 20 points. Seventy-four point two percent of the subject responded that nutrition education is very necessary for patient, and positive responses in the nurse were higher than that nursing assistant(p<0.001). Only 8.6% of the subjects had nutrition education training. The perceptions about a suitable person for nutrition counseling and nutrition education indicated dietitian(69.3%) and nurse(21.3%). Fifty-two point eight percent of the subjects responded that they would not participate in nutrition education themselves and the main reason for this was that they believed lack of expert knowledge(43.4%), and that such courses should be taught by specialist(40.5%). Forty-eight point eight percent of subjects had nutrition counseling experience for patient, and nurses, married nurses and those over 2 years of nursing careers had significantly higher nutrition counseling experience for patient than nursing assistant, unmarried nurses and those under 2 years of nursing careers(p<0.05~p<0.001)
Counseling ; Education* ; Gyeongsangnam-do* ; Humans ; Nursing ; Surveys and Questionnaires ; Single Person

Eccrine spiradenoma is clinically characterized by a solitary, movable, tender nodule occurring most frequently on the ventral surface of the upper body. A striking symptom is paroxysmal pain. Occasionally multiple lesions may be present and may occur in a linear or zosteriform pattern. A 48-year-old female was seen with painful or tender, nomal skin colored, firm nodules distributed in a zosteriform pattern on the right thigh for 10 years, which had been slowly growing. The histopathological features were quite a characteristic of eccrine spiradenoma. We report a rare case of zosteriform network of eccrine spwadenoma occurred on the right thigh.
Female ; Humans ; Middle Aged ; Skin Pigmentation ; Strikes, Employee ; Thigh

Scleroderma is an incidious and chronic disease of unknown cause. The clinical picute of scleroderma is characterized by the apperance of circumscribed of diffuse, hard, smooth, ivory colored areas that are immobile upon upon the underlying tissues. It may be classified to as a localized form (morphea) and a systemic scleroderma or progressive systemic sclerosis (PSS) which is characterized by diffuse involvment of the connective tissue of the skin and certain intemal organs. The authors observed 3 cases of PSS and 6 cases of morphea. They have complained of marked sclerosis or thickening of skin or slowly developing dyspneadue to interstitial pulmonary fibrosis which were confirmed by chest X-ray. Recently, penicillamine-D has been advocated as a beneficial agent in scleroderma by Asboe-Hansen. therefore, penicillamine-D was administered to the above patients. Two of PSS were markedly improved with normal skin softness. Two of morphea were also moderately improved. Other patients remained stationary or no effect.
Chronic Disease ; Connective Tissue ; Humans ; Pulmonary Fibrosis ; Scleroderma, Diffuse ; Scleroderma, Localized ; Scleroderma, Systemic ; Sclerosis ; Skin ; Thorax

No abstract available.