Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory condition involving multiple organs, including the salivary or lacrimal glands, orbit, pancreas, bile duct, liver, kidney, retroperitoneum, aorta, lung, and lymph nodes. It is histologically characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, storiform fibrosis, and obliterative phlebitis. In the thoracic involvement of IgG4-RD, mediastinal lymphadenopathy and perilymphangitic interstitial thickening of the lung are the most common findings. Peribronchovascular and septal thickening and paravertebral band-like soft tissue are characteristic findings of IgG4-RD. Other findings include pulmonary nodules or masses, ground-glass opacity, alveolar interstitial thickening, pleural effusion or thickening, mass in the chest wall or mediastinum, and arteritis involving the aorta and coronary artery. Radiologic differential diagnosis of various malignancies, infections, and inflammatory conditions is needed. In this review, we describe the imaging findings of IgG4-RD and the radiologic differential diagnoses in the thorax.

Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory condition involving multiple organs, including the salivary or lacrimal glands, orbit, pancreas, bile duct, liver, kidney, retroperitoneum, aorta, lung, and lymph nodes. It is histologically characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, storiform fibrosis, and obliterative phlebitis. In the thoracic involvement of IgG4-RD, mediastinal lymphadenopathy and perilymphangitic interstitial thickening of the lung are the most common findings. Peribronchovascular and septal thickening and paravertebral band-like soft tissue are characteristic findings of IgG4-RD. Other findings include pulmonary nodules or masses, ground-glass opacity, alveolar interstitial thickening, pleural effusion or thickening, mass in the chest wall or mediastinum, and arteritis involving the aorta and coronary artery. Radiologic differential diagnosis of various malignancies, infections, and inflammatory conditions is needed. In this review, we describe the imaging findings of IgG4-RD and the radiologic differential diagnoses in the thorax.

Purpose: The study aimed to translate the Paternal Postnatal Attachment Scale (PPAS) into Korean and to evaluate the validity and reliability of the Korean version of the PPAS (K-PPAS). Methods: The PPAS was translated, back-translated, and reviewed by 12 experts and 5 fathers following the World Health Organization's guideline. A convenience sample of 396 fathers with infants in their first 12 months participated in this study. For construct validity, an underlying factor structure and model fit was assessed with an exploratory and confirmatory factor analysis. Convergent and discriminant validity and reliability of the K-PPAS were evaluated. Results: The construct validity of the K-PPAS with 11 items was identified by two-factor structures: healthy attachment relationship, and patience and tolerance. The final model fit was shown acceptable with the normed chi-square = 1.94, comparative fit index = .94, Tucker–Lewis index = .92, root mean square error of approximation = .07, and standardized root mean square residual = .06. This model had acceptable convergent and discriminant validity for each construct with the values of the composite reliability and heterotrait–monotrait ratio at a satisfactory level. Discriminant validity with known groups showed that fathers with no postnatal depression had significantly higher scores on the K-PPAS than those with postnatal depression. Cronbach's α and McDonald's omega coefficient of the K-PPAS was .84 and .83. Conclusions The K-PPAS would be beneficial to measure postnatal attachment among fathers with infants aged 12 months or younger in Korea. However, further studies are suggested to evaluate the applicability of the scale considering the various family structures, such as single or foster parents and multicultural families that exist within the Korean population.

PURPOSE: We investigated the ultrasonographic (US) appearance of metaplastic squamous breast carcinoma with the pathologic correlation. MATERIALS AND METHODS: During an 8-year period, the US appearances of 10 patients with metaplastic squamous breast carcinoma were retrospectively analyzed on the basis of the Breast Imaging and Reporting Data System (BI-RADS) - US lexicon. These 10 patients included 9 patients having invasive adenocarcinomas of the breast with more than 30% squamous metaplasia, and one patient had pure primary squamous cell carcinoma. We correlated the US findings with the pathologic findings. RESULTS: On US, the majority of the tumors showed oval shapes (70%), indistinct margins (50%), parallel orientation (80%), echogenic halos (60%), complex echogenicity with solid and cystic components (60%), and posterior enhancement (70%). The findings of calcifications (20%) and metastatic axillary lymph nodes (10%) were rare. On pathologic examination, half of the tumors showed infiltrative microscopic margins. All six cases showing complex echogenicity with solid and cystic components on US were pathologically related to the cystic or necrotic portion, and three of these cases had hemorrhage. CONCLUSION:On US, metaplastic squamous breast carcinoma mainly manifested as oval, complex, echoic masses with indistinct margins and posterior enhancement that was pathologically related to the cystic or necrotic portions.
Adenocarcinoma ; Breast Neoplasms* ; Breast* ; Carcinoma, Squamous Cell ; Hemorrhage ; Humans ; Information Systems ; Lymph Nodes ; Metaplasia ; Retrospective Studies

Pulmonary mucormycosis is an opportunistic infection manifested by a fatal angioinvasive fungal pneumonia in immunocompromised patients or those suffering from uncontrolled diabetes. The radiologic findings are nonspecific, but there have been several reports of cases of pulmonary mucormycosis in which characteristic endobronchial lesions were present, with a more indolent clinical course in diabetic patients. We describe a case of pulmonary mucormycosis in a diabetic patient in whom endobronchial involvement was apparent.
Humans ; Immunocompromised Host ; Mucormycosis* ; Opportunistic Infections ; Pneumonia

Decompression sickness is a self contained underwater breath apparatus (SCUBA)-related injury with various symptoms and is considered an extreme emergency condition. This is a case of pulmonary involvement in decompression sickness in a 26-year-old SCUBA diver. Although pulmonary involvement in decompression sickness is a potentially severe condition that requires immediate treatment, this condition can be under- or misdiagnosed, and evaluation of this disease by imaging findings is not clearly understood. We experienced a case of pulmonary involvement in decompression sickness and herein present the chest computed tomography and simple radiograph findings associated with this condition.
Decompression ; Decompression Sickness ; Dyspnea ; Emergencies ; Thorax

This study was performed to develop and evaluate a semi-automatic seed localization algorithm from magnetic resonance (MR) images for interstitial prostate brachytherapy. The computerized tomography (CT) and MR images (3 mm-slice thickness) of six patients who had received real-time MR imaging-guided interstitial prostate brachytherapy were obtained. An automatic seed localization method was performed on CT images to obtain seed coordinates, and an algorithm for seed localization from MR images of the prostate was developed and tested. The resultant seed distributions from MR images were then compared to CT-derived distribution by matching the same seeds and calculating percent volume receiving 100% of the prescribed dose and the extent of the volume in 3-dimensions. The semiautomatic seed localization method made it possible to extract more than 90% of the seeds with either less than 8% of noises or 3% of missing seeds. The mean volume difference obtained from CT and MR receiving 100% of the prescribed dose was less than 3%. The maximum extent of the volume receiving the prescribed dose were 0.3, 0.6, and 0.2 cm in x, y, and z directions, respectively. These results indicate that the algorithm is very useful in identifying seeds from MR image for post-implant dosimety.
Algorithms ; Brachytherapy/*methods/statistics & numerical data ; Humans ; Iodine Radioisotopes/*administration & dosage ; *Magnetic Resonance Imaging, Interventional/statistics & numerical data ; Male ; Prostatic Neoplasms/*pathology/radiography/*radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted ; Tomography, X-Ray Computed/statistics & numerical data ; Tumor Burden

A wide variety of pulmonary disorders related to hemodialysis or pre-existing renal disease occurs in hemodialysis patients. The disorders may be classified as 1) pulmonary abnormalities associated with chronic renal failures; 2) pulmonary complications arising during hemodialysis; 3) pulmonary infection; or 4) pulmonary-renal syndrome. An awareness of the various possible pulmonary disorders arising in hemodialysis patients may be helpful for the proper and timely management of such patients. We describe and illustrate various radiographic and CT findings of variable pulmonary disorders in hemodialysis patients.
Humans ; Renal Dialysis* ; Renal Insufficiency ; Vasculitis

PURPOSE: To clarify the value of mass screening for thyroid cancer by ultrasonography. MATERIALS AND METHODS: We evaluated the incidence of thyroid nodules and the detection rate of malignant nodules in 2856 patients who underwent screening thyroid ultrasonography while undergoing breast ultrasonography. We also analyzed the ultrasonographic characteristics of nodules in the screening (34 patients) and clinical (48 patients) groups which were diagnosed with thyroid cancer. RESULTS: The incidence of thyroid nodules detected by ultrasonography was 39% and the detection rate of thyroid cancer was 1.19% in the screening group and 17% in the clinical group. The mean size of nodules in clinical group was larger than that in the screening group (p<0.05) and the prevalence of nodules with ill-defined margin in the screening group was higher than that in the clinical group (p<0.05). There was no significant difference in internal echogenicity, shape, presence of internal calcifications, lymph node metastasis and extrathyroidal extension between the two groups. CONCLUSION: Although the incidence of thyroid cancer was low, sonographic screening for thyroid cancer while undergoing breast ultrasonography could be valuable.
Breast* ; Early Detection of Cancer ; Humans ; Incidence ; Lymph Nodes ; Mass Screening* ; Neoplasm Metastasis ; Prevalence ; Thyroid Gland* ; Thyroid Neoplasms* ; Thyroid Nodule ; Ultrasonography ; Ultrasonography, Mammary*

OBJECTIVE: To evaluate the reliability of virtual non-contrast (VNC) images reconstructed from contrast-enhanced, dual-energy scans compared with true non-contrast (TNC) images in the assessment of high CT attenuation or calcification of mediastinal lymph nodes. MATERIALS AND METHODS: A total of 112 mediastinal nodes from 45 patients who underwent non-contrast and dual-energy contrast-enhanced scans were analyzed. Node attenuation in TNC and VNC images was compared both objectively, using computed tomography (CT) attenuation, and subjectively, via visual scoring (0, attenuation < or = the aorta; 1, > the aorta; 2, calcification). The relationship among attenuation difference between TNC and VNC images, CT attenuation in TNC images, and net contrast enhancement (NCE) was analyzed. RESULTS: CT attenuation in TNC and VNC images showed moderate agreement (intraclass correlation coefficient, 0.612). The mean absolute difference was 7.8 +/- 7.6 Hounsfield unit (HU) (range, 0-36 HU), and the absolute difference was equal to or less than 10 HU in 65.2% of cases (73/112). Visual scores in TNC and VNC images showed fair agreement (kappa value, 0.335). Five of 16 nodes (31.3%) which showed score 1 (n = 15) or 2 (n = 1) in TNC images demonstrated score 1 in VNC images. The TNC-VNC attenuation difference showed a moderate positive correlation with CT attenuation in TNC images (partial correlation coefficient [PCC] adjusted by NCE: 0.455) and a weak negative correlation with NCE (PCC adjusted by CT attenuation in TNC: -0.245). CONCLUSION: VNC images may be useful in the evaluation of mediastinal lymph nodes by providing additional information of high CT attenuation of nodes, although it is underestimated compared with TNC images.
Adult ; Aged ; Aged, 80 and over ; Calcinosis/*radiography ; Contrast Media/diagnostic use ; Female ; Humans ; Image Processing, Computer-Assisted ; Lymph Nodes/*radiography ; Male ; Mediastinum/*radiography ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed/*methods