A 6-year-old boy with porokeratotic eccrine ostial and dermal duct nevus on the left sole is reported. The patient was born with keratotic plugs, each measuring 1-2 mm in diameter, on the left sole. Light-microscopic examination revealed epidermal invagination and cornoid lamella, which was found to be connected with hyperplastic intraepidermal and dermal eccrine duct. The present case can be histologically differentiated from nevus comedonicus and punctate porokeratotis.
Child ; Humans ; Male ; Nevus*

No abstract available.
Angiokeratoma* ; Hypertrophy*

This study was undertaken to investigate immunological mechanisms in Behçet's syndrome, a function considered important in the pathogenesis of the disease. The activity of interleukin-2 (IL-2), which is believed, to play a central role in the regulation of both cell-mediated and humoral T cell-dependent immune responses, measured in 46 patients with complete, in-complete or suspected Behçet's syndrome. The results were as follows: 1 . There was no significant difference between the average IL-2 activity of patients and control group. 2. For each clinical subtype of Behçet's syndrome, IL-2 activity was lower than the control value, but the difference was not statistically significant. 3. In mucocutaneous and ocular types, the greater the clinical symptoms, the lower the value of IL-2 activity. However, the decrease of IL-2 activity was not statistically significant. In conclusion, IL-2 activity of phytohemaggludnin (PHIS-stimulated peripheral blood lymphocytes in patients with Behçet's syndrome was not significantly decreased compared to control population.
Humans ; Interleukin-2* ; Lymphocytes

No abstract available.
Onychomycosis* ; Urea*

We report a 19-year-old man with hyperkeratosis of nipple and areola which is a part of an epidermal nevus. He did not have a history of endocrinopathy or synthetic steroid therapy. The lesion, a fingertip sized verrucous dark browncolored macule on left upper back, had spread into left-anterior chest wall and had involved nipple and areola to make them hyperkerstotic and verrueous. Histologic section from the on left areola showed hyperkeratosis, papillomatosis, acanthosis and increased pigmentation in the basal cell layer. Chernical peeling with 30% trichloroacetic showed favorable response.
Humans ; Nevus ; Nipples ; Papilloma ; Pigmentation ; Thoracic Wall ; Trichloroacetic Acid ; Young Adult

No abstract available.
Kidney*

PURPOSE: A clinical diagnosis of meningitis is difficult because of the paucity of physical findings in children. Not all of the meningitis patients show nuchal rigidity, Kernig's sign or Brudzinski's sign. Lumbar punctures were done because of unexplained fever, changes in behavioral or mental status, seizures or skin petechiae in febrile patients. But sometimes cerebrospinal fluid(CSF) findings are not compatible with menigitis for those whose clinical symptoms indicate menigitis. Pediatricians are frequently confronted to the problem of a sick child whose CSF has no white blood cells but the child has a meningeal irritation sign. Therefore, the levels of CSF beta2 microglobulin from children with positive meinigeal irritation signs were examined to evaluate the diagnosis of meinigitis. METHODS: From March to August 2002, We examined the levels of CSF beta2 microglobulin from children with positive meningeal irritation signs by competitive radioimmunoassay in 35 suspected meingitis patients and 12 control patients in the Department of Pediatrics of Chungnam National University Hospital. RESULTS: In 35 suspected menigitis patients, 20 patients were diagnosed as meningitis and 15 patients were no evidence of meningitis in their CSF findings. In the WBC counts of the CSF, meinigitis patients had 268/mm3 and meningismus patient had 2.3/ mm3 on average. In the levels of the CSF beta2 microglobulin concentrations, the two groups were not different. For the 20 meningitis patiens, the average value was 0.193+/-0.054 while it was 0.169+/-0.028 for the 15 meningismus patients and 0.102+/-0.021 for the 12 control patients(P<0.05, <0.05, P>0.05) CONCLUSION: These data demonstrate that the meningeal irritation sign is a meaningful sign for meningitis but the initial CSF findings do not always confirm the diagnosis. So, if patients have a meningeal irritation sign, the patient should be carefully examined and additional diagnostic tools such as the CSF beta2 microglobulin concentration can be used.
Cerebrospinal Fluid* ; Child* ; Chungcheongnam-do ; Diagnosis ; Fever ; Humans ; Leukocytes ; Meningism ; Meningitis ; Muscle Rigidity ; Pediatrics ; Purpura ; Radioimmunoassay ; Seizures ; Skin ; Spinal Puncture

PURPOSE: To compare the effectiveness of the in-phase(IP) sequence and the opposed-phase(OP) sequence in the detection of focal hepatic lesions in the single breath-hold hepatic MR imaging with fast gradient T1-weighted pulse sequences. MATERIALS AND METHODS: If and OP T1-weighted breath-hold imaging was performed using fast gradient echo sequences in 45 patients referred for known focal hepatic lesions, in which 78 lesions were detected. There blind readers independently reviewed the images for lesion detectability. The signal-to-noise ratio(SNR) of the liver, the lesion-to-liver contrast-to-noise ratio(CNR) and the liver-to-spleen CNR were also compared. A consensus was reached by three readers to determine which sequence is better in image quality. RESULTS: On OP images, 61(78%), 61(78%), and 63(89%) lesions were correctly identified for reader 1, 2 and 3, respectively. On IP images, 66(85%), 65(83%), and 65(93%) lesions were detected for each reader, respectively. When two image sets were combined, 71(91%), 69(88%), and 76(97%) lesions respectively were detected for each reader. In cases of hepatocellular carcinoma, liver-to-lesion CNR was greater on the OP images(p<0.05), but in other lesions significant differences was not demonstrated. Liver-to-spleen CNR was higher in OP images(p<0.1), but the SNR of the liver was higher on the If images. CONCLUSION: Use of both If and OP imaging can be helpful to avoid erroneous missing of some focal hepatic lesions.
Carcinoma, Hepatocellular ; Consensus ; Humans ; Liver* ; Magnetic Resonance Imaging*

PURPOSE: Carcinosarcomas are rare neoplasms in which both malignant epithelial and mesenchymal elements are identified. We have found only twenty one cases of primary cutaneous carcinosarcoma in the English language literature. Therefore it has been difficult to diagnosis because its unclear etiology and low frequency. METHODS: A 31-year-old young man with a protruding mass on his ankle dorsum was examined. The tumor was 7 x 6 x 3 cm sized and arose from a burn scar. The mass was wide excised and applied split thickness skin graft. Characteristic pathologic finding was a mixture of squamous cell carcinoma and malignant fibrous histiocytoma. RESULTS: Three months after the operation, the patient died of multiple metastasis to the liver, lung and finally of sepsis despite adjuvant chemotherapy and adjuvant radiotherapy. CONCLUSION: If a metastatic cutaneous carcinosarcoma is diagnosed, wide excision is required. There should be more aggressive management to minimize the risk of recurrence. Further research into the etiology and pathophysiology of the disease and a more careful differential diagnosis may allow improvement in treatment.
Adult ; Animals ; Ankle ; Burns ; Carcinoma, Squamous Cell ; Carcinosarcoma ; Chemotherapy, Adjuvant ; Cicatrix ; Diagnosis, Differential ; Histiocytoma, Malignant Fibrous ; Humans ; Liver ; Lung ; Neoplasm Metastasis ; Recurrence ; Sepsis ; Skin ; Transplants ; Ulcer

PURPOSE: This study evaluated the usefulness of ultrasonography for a diagnosis of acetabular labral tear in femoroacetabular impingement (FAI). MATERIALS AND METHODS: From March 2010 to October 2011, an ultrasonographic examination was performed in 58 patients(58 hips: 26 men and 32 women) with acetabular labral tear. The sensitivity and positive predictive value of ultrasonography were evaluated for 58 cases with acetabular labral tear confirmed by hip arthroscopy. RESULTS: The sensitivity and positive predictive value for an acetabular labral tear using ultrasonography was 89.6% and 100%, respectively. The concordance rate of an acetabular labral tear between arthroscopy and ultrasonography was 84.6%. CONCLUSION: Hip ultrasonography can make a significant contribution to a pathologic diagnosis and isa useful diagnostic tool for acetabular labral tears.
Arthroscopy ; Femoracetabular Impingement ; Hip ; Humans ; Male