1.Clinical study about effects of the acute fasting hyperglycemia and type 2 diabetes mellitus on ischemic preconditioning in patients with the first-ever acute anterior circulation infarction
Chinese Journal of Neurology 2008;41(12):820-823
Objectives To assess whether prodromal transient ischemic attack (TIA) has beneficial effects on type 2 diabetic patients and those had acute fasting hyperglycemia with the first-ever acute anterior circulation infarction.Methods One hundred and seventy patients with first-ever ischemic acute anterior circulation infarction were involved.According to whether they had type 2 diabetes mellitus,patients were divided into group A (non-diabetic patients) and group B (diabetic patients).Mean infarct volume was also compared between patients with pro-TIA and without pro-TIA in group A and B,and each group with acute hyperglycemia too.Results In group A,prodromal TIA was associated with a smaller infarct volume (M: 2.61 cm3 vs 5.99 cm33 Z=-2.69,P=0.007).On the contrary,in group B,there was no significant difference in infarct volume (M: 3.25 cm3 vs 11.0 cm3,Z=-1.699,P=0.08) between patients with and without prodromal TIA.In group A patients absent with acute fasting hyperglycemia,infarct volume significantly smaller in patients with prodromal TIA than in those without (M: 2.69 cm3 vs 6.46 cm3,Z=-2.34,P=0.019) ; In patients with acute fasting hyperglycemia,there was no a significant difference in infarct volume (M: 2.61 cm3 vs 5.69 cm3 ,Z=-1.218,P=0.27).However,among group B patients present or absent with acute impaired fasting glucose,there was no significant difference in infarct volume in patients with or without prodromal TIA.Conclusion Diabetes mellitus and the acute fasting hyperglycemia might prevent the ischemic preconditioning.
2.DETERMINATION OF THE SACROILIAC ARTICU-LAR SURFACE WITH SPECIAL REFERENCE TO THE STRESS LOADING
Yongzhen WANG ; Qiangsu GUO ; Jinbao WU ; Xueming ZHENG
Acta Anatomica Sinica 1957;0(04):-
The diameters and projection area of the articular surfaces, contributed to the formation of the sacroiliac joint, were determined on 50 sets of pelvic bones with image analysing apparatus.By drawing a line connecting the most anterior point of the prominence to the deepest point of the posterior incisure, the articular surface may be divided into a superior and an inferior portions. The inferior portion was larger than the superior portion. Each portion of the articular surface on the ilium is slightly larger than that on the sacrum.In order to explore the relationship between the form of the articular surface and its function in transmitting the gravity of the human body, the stress of the neighbouring area near the anterior margin of the articular surface was determined. Moreover, the bony architecture on the cross section passing through the articular surface was observed. It suggests that the strain in the neighbouring area was in linear equation with the gravity loaded on the spinal column. The strongest stress was determined at the anterior margin of the anterior prominence and the thickness of the cortex lying on the relevant bones appears most obvious at the same sites. These results further improve that the bony architecture was consistent with the strain in bearing the body weight. Besides, the form of the articular surface was also adapted to its function.
3.Distribution and influence factors of Anammox bacteria in sewage treatment systems.
Bingyu ZHENG ; Yongzhen PENG ; Liang ZHANG ; Anming YANG ; Shujun ZHANG
Chinese Journal of Biotechnology 2014;30(12):1817-1827
Nitrogen removal techniques based on Anammox process are developing rapidly these years. The distribution and diversity of Anammox have become important research directions. A variety of Anammox have been detected till now, of which only Kuenenia and Brocadia are often detected in wastewater treatment systems. In addition, in a single niche there is only one type of Anammox bacteria. However, the distribution mechanism and transformation of Anammox bacteria in different niches are still ambiguous. Therefore, the distribution of Anammox in various conditions was summarized and analyzed in this article. And the key factors influencing the distribution of Anammox were concluded, including substrate concentration and the specific growth rate, sludge properties and microbial niche, the joint action and influence of multiple factors. The engineering significance research on the distribution and influencing factors of Anammox bacteria in the sewage system and proposed research prospects were expounded.
Ammonia
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chemistry
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Anaerobiosis
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Bacteria
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Nitrogen
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chemistry
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RNA, Ribosomal, 16S
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Sewage
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microbiology
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Waste Disposal, Fluid
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Waste Water
4.Effect of rehabilitation skills training program on suicide and relapse prevention of patients with depression
Chuanfang LENG ; Wei ZHENG ; Lirong TANG ; Rui CHEN ; Jiaojiao ZHOU ; Xiaoshu GAI ; Yongzhen WENG ; Xin MA ; Yingqiang XIANG
Chinese Journal of Nervous and Mental Diseases 2017;43(2):89-92
Objective This study aims to investigate the effect of rehabilitation skills training on suicide and relapse prevention of patients with depression.Methods Eighty patients were randomly divided into two groups.One group accepted depression rehabilitation skills training and the other group accepted general health education for 4 weeks.Both groups were followed up by 12 months,and the number of relapse and suicide and the score of Health-related quality of life made by Word Health Organization (WHOQOL-BREF) were recorded.Results The rate of relapse (10.0% vs.42.5%) and hospitalization (5.0% vs.20.0%) were lower in skills training group than in control group (P<0.05).Rate of seeking help of suicide was higher in skills training group than in control group (25.5% vs.7.5%) (P<0.05).The suicide mortality was insignificantly different between two groups (0.0% vs.2.5%) (P>0.05).The scores of WHOQOL-BREF were significantly higher in skills training group than in control group in follow-up (P<0.05).Conclusions Rehabilitation skills training program can not only reduce the rate of relapse and suicide but also improve the quality of life of patients with depression.
5. Status of non-steroidal anti-inflammatory drugs use in areas with a high incidence of upper gastrointestinal cancer in China: a multi-center cross-sectional survey
Shuanghua XIE ; Ru CHEN ; Deli ZHAO ; Yuqin LIU ; Changqing HAO ; Yongzhen ZHANG ; Guohui SONG ; Zhaolai HUA ; Jialin WANG ; Shuzheng LIU ; Liwei ZHANG ; Dantong SHAO ; Yu QIN ; Minjuan LI ; Jiachen ZHOU ; Rongshou ZHENG ; Guiqi WANG ; Wenqiang WEI
Chinese Journal of Preventive Medicine 2019;53(11):1098-1103
Objective:
To describe the status of non-steroidal anti-inflammatory drugs (NSAIDs) use in areas with a high incidence of upper gastrointestinal cancer in China.
Methods:
This study was based on the National Key Research and Development Program of "National Precision Medicine Cohort of Esophageal Cancer" and "Study on Identification and Prevention of High-risk Populations of Gastrointestinal Malignancies (Esophageal cancer, Gastric cancer and Colorectal cancer)" . From January 2017 to August 2018, 212 villages or communities with a high incidence of esophageal cancer or gastric cancer were selected from 12 regions in 6 provinces. A total of 35 910 residents aged between 40 and 69 years old who met the inclusion criteria and signed the informed consent were investigated and enrolled in this study. The use of NSAIDs, demographic characteristics, health-related habits, height, weight, and blood pressure were collected by the questionnaire and physical examination. The status of main NSAIDs (aspirin, acetaminophen and ibuprofen) use with the difference varying in genders, age groups and regions were analyzed by using χ2 test and Cochran-Armitage trend analysis method.
Results:
Of 35 910 subjects, the mean age was (54.6±7.1) years old and males accounted for 43.42% (15 591). The overall prevalence of NSAIDs intake was 4.56% (1 638), but it significantly varied in different provinces (