The pathogenesis of cancer and related treatment were discussed.With regard to cancer,WANG emphasized the vital qi tangled theory,evil dominant theory,theory of blood stasis resulting tumor,non-blood stasis theory,sputum and toxin harm theory.As for cancer treatment,method of expelling stagnation,regulating qi,eliminating phlegm,softening hard mass and detoxicating should be used according to the specific syndrome.

Based on the subtle discussion of changing rules and its principles of Six Qi movement recorded by one chapter named Liu Wei Zhi Da Lun in the Huang Di Nei Jing Su Wen about rules of Heaven divided by Six, Six Qi and year evolutive phase, Six Qi dominating the time, and guest climatic Qi adding to fixed host Qi, etc, this article explained the changes of influence of Heaven space-time on the human body from the angle of image thinking, focused on the key point of humanity conforming to the nature of the core of Chinese philosophy, and appealed readers to come back to the original thinking of China-image thinking.

The relationship between genetic polymorphisms and onset or development of disease have become a hot point in medical research presently. So as to study the distribution of genetic polymorphisms of stroke associated genes in different people will aid to deepen cognition to pathogenic mechanism of stroke and heighten prevention and cure ability to this disease. The article summarizes the progress in genetic polymorphisms of some stroke associated genes (MTHFR,ACE,AGT,ApoE,eNOS).

Objective To introduce a proposal that can standardize the clinical information of urine manifestation in Chinese medicine.Methods A hypothesis of symptomatic units was proposed in this paper,herein,the attribute,name and definition of the symptomatic units of urine manifestations in the clinical records of Chinese medicine in the past dynasties were summarized according to the stipulation of logic classification and denomination of a scientific term.Results The 23 symptomatic units,2 bounds and their assembly can express 3867 descriptions on the clinical manifestation of urine.Conclusion The symptomatic unit is a feasible hypothesis that can simplify the clinical information of Chinese medicine.The attribute extraction,denomination and definition may become one of the effective procedures to standardize the clinical information of Chinese medicine.

Comparative effectiveness research (CER) has gained more and more popularity, which brought great response in the USA and other developed Western countries. There is no doubt that CER is a new idea and a milestone in health care research. CER is also known as "patient-centered outcomes research", which means patient is the core element in the whole system of CER. Chinese medicine could make new achievements and further development by introducing CER into clinical research. This article mainly introduced the background, features and contents of CER and summarized how to conduct CER in Chinese medicine by referring to some published literature in order to enlighten Chinese medicine researchers.

Objective To investigate an effective method for detecting lymphatic micrometastasis in gastric carcinoma.Methods RT-PCR technique was applied to examine MMP-7 mRNA in 94 lymph nodes in 24 cases of gastric carcinoma.Results Routine pathological method detected lymphatic metastasis in 54 lymph nodes,while MMP-7 mRNA RT-PCR showed positive in 78 lymph nodes. When re-examination for the 28 negative lymph nodes in the initial pathological examination and positive in RT-PCR, 8 lymph nodes with metastasis were found by routine pathological method.2 of 5 patients whose lymph nodes were negitive in pathological examination,but positive in MMP-7mRNA were found liver metastasis 16 and 22 months after radical gastrectomy. Conclusions MMP-7 mRNA RT-PCR is a sensitive method for detecting lymphatic micrometastasis for patients with gastric carcinoma. It is a great help for eluvating the postoperative prognosis and supplemental treatmemt.

OBJECTIVE: To probe into a construction model of TCM resource science meeting the need of teaching practice and fitting for teaching and education, which focuses on the both characteristics of TCM and nature of resource. METHODS: Guided by "the three basic key points" theory, the content of the construction of TCM resource science are analyzed, such as foundational theories, elementary knowledge and basic skills, etc., considering academic characteristics and position, write of textbook. RESULTS: Based on current demand, theory analysis, content of system and advantages of the construction of TCM resource science, the new idea characterized with teaching being harmonious with education was put forward and fit for "the three basic key points" theory. CONCLUSIONS: The construction model of TCM resource science is an efficient and technical way to meet the demand of teaching.

Alzheimer's disease (AD) is a progressive, degenerative disease of the brain, which causes learning and memory to become seriously impaired. AD not only influences the patient's quality of life, but also places a great burden on caregivers. With the increasing of aging population, the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregivers' life.The cause and progression of Alzheimer's disease are not well understood. Currently used treatments include pharmaceutical and psychosocial ones, each offering a small symptomatic benefit. Actually, there are still no available medicines and treatments to delay the progression of the disease. Therefore, the development of a new ideal medicine to treat AD patients becomes the first priority. In recent years, most researchers have turned to natural products, hoping to find a drug candidate to cure AD patient. Baicalein, a traditional Chinese medicine extracted from Scutellaria Baicalensis (Chinese herb), has been demonstrated holding the properties of anti-inflammatory, anti-apoptosis, anti-oxidant, and improving learning and memory of human brain. Baicalein is becoming a potential ideal medicine for treating AD patient.

AIM: To investigate the effects of simvastatin on myocardial fibrosis and connective tissue growth factor (CTGF) in renovascular hypertensive rats. METHODS: The experimental rats were randomly divided into three groups, such as sham operation group rats, hyperpiesia rats and hyperpiesia rats treated with simvastatin (5 mg㎏kg -1 ?d -1 ). Systolic blood pressure (SBP) was measured and collagen concentration (Coll) was also detected in terms of hydroxyproline concentration. VanGieson and immunohistochemistry staining combined with computed morphometry were used to evaluate the total collagen volume fraction (CVF) and CTGF expression in left ventricular tissue. RESULTS: Compared with sham operation group rats, the SBP,CVF, Coll and CTGF expression increased markedly in hyperpiesia rats (P

Objective:To evaluate of the patient with stroke and analyze its influencing factors.Methods:Quality of life was evaluated by questionnare GQOLI-74,and the influencing factors were analyzed with simple factor analysis and stepwise regression in 360 cases of stroke.Results:The total scores of quality of life in the patients were very low,the score from high to low in order was substance dimension,mental dimension,social dimension,somatic dimension;and 17 factors including age,Barthel index,TCM syndrome,etc.had statistically significant effects on quality of life.Conclusion:Quality of life in the patient with stroke decreases commonly,injury of the somatic function is the largest and injury of substance function is the smallest.Social factor,medical factor and TCM syndrome all have obvious effects on quality of life.