The endotoxemia model was established by intraabdominal injection of endotoxin Coli B. (E. Coli O55B5,8 mg/kg weight)in albino rats. Two hours before administration of endotoxin, the ejiao recovery-pulse decoction was perfused into the stomach tube of the rats in the experimental group (10mg/kg weight), and 12h later, the platelets were counted, kaolin activated partial thromboplastin time (KPTT), prothrombin time (PT) and thrombin time (TT) were measured, and malondialdehyed (MDA) levels in plasma and platelet were determined by thiobarituric acid (TBA) fluorometry. The results demonstrate that the ejiao recovery-pulse decoction could prevent from peripheral platelet dropping, KPTT and TT prolonging and MDA level rising which were caused by endotoxin.

Objective To investigate the health education needs of patients undergoing radiofrequency ablation of atrial fibrillation and to provide a basis for the formulation of targeted health education programs.Methods A self-designed questionnaire on the health education needs of patients with atrial fibrillation undergoing radiofrequency ablation was designed based on the Kano model.A total of 190 patients with atrial fibrillation who underwent radiofrequency ablation in Grade 3A Hospital of Yunnan Province from February to July 2023 were investigated,and their health education needs were determined according to the Kano model.Results A total of 190 questionnaires were sent out,180 valid questionnaires were recovered,and the effective recovery rate was 94.74%.Among the 32 health education needs of patients undergoing radiofrequency ablation of atrial fibrillation,including 6 necessary needs,13 expected needs,11 charismatic needs,and 2 undifferentiated needs,no reverse demand was found.The importance-satisfaction matrix diagram shows that 12 items are located in the dominant area,11 items in the area to be improved,7 items in the maintenance area,and 2 items in the secondary improvement area.Conclusion The Kano model can analyze the health education needs of patients undergoing radiofrequency ablation of atrial fibrillation in multiple dimensions,and provide a reference for doctors and nurses to further develop the content and form of patient-oriented health education.