1.Different vaginal bacteria inspection method analysis and comparison
Yongsheng NIU ; Fang ZHAO ; Dongsheng ZHANG
Chinese Journal of Postgraduates of Medicine 2011;34(30):9-11
ObjectiveTo investigate the characteristics of three vaginal bacteria inspection methods of Amsel method,gram staining Nugent score method and bacterial vaginosis (BV) Blue methodMethods The leucorrhea specimen of 99 vaginal fluid abnormal patients were examined by Amsel method,gram staining Nugent score method and BV Blue method,then compared and analyzedResultsThe positive rate was 28.28% (28/99) in Amsel method,47.47%(47/99) in gram staining Nugent score method and 16.16% (16/99) in BV Blue method.There were significant differences among three methods(P< 0.01 ).The specificity and sensitivity of gram staining Nugent score method was higher.ConclusionThe three vaginal bacteria inspection methods have advantage and shortcoming individually,suspecting patients should be followed up to detect and diagnose in chnic,or detected by many methods.The specificity and sensitivity of gram staining Nugent score method is higher,but BV Blue method is simple,faster,which has higher value in detection and diagnosis in BV.
2.MR Diagnosis of Extrahepatic Biliary Obstructive Disease
Fang TIAN ; Yongsheng DING ; Jun YUAN
Journal of Practical Radiology 2001;0(09):-
Objective To study MR manifestations of biliary obstructive disease.Methods MR examination (Philips Gyroscan INTERA 1.0T)in 69 patients with biliary obstructive disease were performed.The conventional sequences included:T1WI/FFE,T2WI/TSE,T2WI/SPIR and contrast-enhanced at axial position,coronal B-FFE and MRCP.All images in all cases were compared with the results of operation and pathology.Results 43 cases were benign disorder,of them,42 cases were choledocholithiasis,one case was choledochal cyst.Choledocholithiasis presented as single or multiple round or ovoid with low signal.The direct sign of malignant lesions (26 cases) was the masses with slightly high signal at the obstructive part,the indirect sign of malignant lesions was obstruction or narrow of bile duct. The MR diagnostic accuracy of obstructive location was 100%, and the accuracy for evaluating the causes of obstruction was 89.9%.Conclusion MRCP combining with B-FFE and routine MRI, analysising the direct sign and indirect sign, can improve the diagnostic accuracy of obstructive jaundice.
3.Investigation on the Effect of Jieduquyuziyin Methods on Decreasing the Dosage of Glucocorticoid and Protecting the Hypothalamic-pituitary-adrenal Axis in Systemic Lupus Erythematosus
Yongsheng FANG ; Chengping WEN ; Yongwei LI
Journal of Zhejiang Chinese Medical University 2006;0(02):-
0.05),while with significant difference in the second therapy course(P
4.Clinical study on left ventricular hypertrophy related arrhythmia in patients with primary hypertension.
Yongsheng XING ; Tianming DENG ; Fang WANG
Chinese Journal of Practical Internal Medicine 2001;0(10):-
Objective To investigate the correlation between arrhythmia and left ventricular hypertrophy in patients withprimary hypertension. Methods 12-lead synchronous resting electrocardiogram. ambulatory electrocardiogram and echo-cardiogram were obtained from 246 patients with primary hypertension. Left ventricular mass index (LVMI ) was meas-ured as previous reference. Results The average LVMI of myocardium hypertrophy group (151.6? 15. 8g/m~2) signif-canily increased compared with that of the control group (P
5.Investigation of the correlation between a group of metastasis-associated proteins and metastatic potency in breast carcinoma
Aiju FANG ; Yongsheng GAO ; Shengmei LI ; Wenjun LIU ; Bin MENG
Chinese Journal of General Surgery 2000;0(11):-
Objective To investigate the expression and the significance of a group of metastasis-associated proteins in invasive ductal breast carcinoma(IDC).Methods Tissue microarray containing 247 IDC specimens was constructed.The expressions of ?-B crystallin,CD44v6,MMP-2 and TIMP-2 were detected by immunohistochemistry,and the relation between the expression of these proteins and the clinicopathologic character was analyzed.Results(1) The expression rates of ?-B crystallin,CD44v6,MMP-2 and TIMP-2 in IDC were 70.0%,61.5%,57.5% and 57.1% respectively,and significantly higher than those of normal breast tissues(P
6.CT Analysis of the Lumbar Degenerative Spondylolisthesis(A Report of 125 Cases)
Yao CHEN ; Yongsheng DING ; Xiaowei NI ; Fang TIAN
Journal of Practical Radiology 2001;0(10):-
Objective To explore the etiology of lumbar degenerative spondylolisthesis(DS)by analyzing its CT manifestations.Methods The location,degree and angle of inclination of lumbar facet joints were measured in 125 cases with 131 spondylolisthesis.Results The angle of inclination of lumbar facet joints was
7.Clinicopathologic features and prognostic factors of 205 patients with pretreated metastatic breast cancer
Fang WANG ; Chunfang HAO ; Yongsheng JIA ; Xiaodong LIU ; Zhongsheng TONG
Chinese Journal of Clinical Oncology 2014;(17):1103-1107
Objective:To analyze the prognostic factors in patients with metastatic breast cancer (MBC). Methods:A total of 205 patients with pretreated MBC were included in this study. These patients were admitted to the Tianjin Medical University Cancer Insti-tute&Hospital and had undergone radical surgery of breast cancer between January 2008 and December 2010. The clinicopathologic information of the patients was collected in this retrospective analysis. Results: The median overall survival of the patients was 32 months (1 month to 132 months). Luminal A, Luminal B, HER-2 overexpression, and triple-negative patients had a median overall sur-vival of 36 months (4 months to 132 months), 32 months (7 months to 122 months), 29 months (1 month to 85 months), and 24 months (1 month to 98 months), respectively. Univariate analysis showed that lymph node metastases, clinical stage, molecular type, visceral disease, first multiple metastatic sites, and shorter metastasis-free interval were significantly associated with poor outcomes. In multivar-iate analysis, lymph node metastases, clinical stage, molecular type, visceral metastasis, and the number of first metastatic sites were significant predictors of patient survival. Conclusion:Lymph node metastasis, clinical stage, triple-negative breast cancer, and visceral metastasis were used as independent poor prognostic indicators for survival in patients. Results of this study may assist physicians in evaluating the survival potential and determining the appropriate therapeutic strategy for MBC patients.
8.Correlation analysis of renal function and serum cystatin C in patients with kidney damage secondary to cirrhosis
Fang ZHAO ; Yongsheng NIU ; Dongsheng ZHANG ; Jianjing SHANG
Chinese Journal of Primary Medicine and Pharmacy 2014;21(11):1678-1680
Objective To investigate the correlation between serum cystatin C(Cys-C)and renal function in patients with renal damage secondary to cirrhosis.Methods 129 patients with liver cirrhosis were selected,according to the measured glomerular filtration rate (GFR) as the gold standard for evaluation of renal function,patients were divided into group A(cirrhosis with normal renal function),group B(cirrhosis following renal insufficiency),group C (cirrhosis secondary to renal failure).The concentration of Cys-C was compared among three groups,and the serum creatinine(Scr),serum proteins ball micro β2 (β2-MG),creatinine clearance (Ccr) were detected.Results Cys-C,Scr,β2-MG,Ccr and other indicators of A,B,C three groups increased or decreased with the severity of impaired renal function(t =6.65,6.85,6.58,4.54,all P < 0.05).The abnormal detection rates of Cys-C,Scr,Ccr,β2-MG in A group were 31.1%,11.1%,8.9%,26,7%,those in B group were 83.7%,30.2 %,34.9%,46.5%,those in C group were 100.0%,85.4%,87.8%,95.1%.Conclusion Serum Cys-C concentration is a sensitive marker to evaluate glomerular filtration,it has accurate and reliable clinical significance in the early diagnosis of liver cirrhosis secondary to kidney damage.
9.Analysis of human resources in TCM hospitals in China
Gelin ZHENG ; Xiaodong SUN ; Yongsheng YANG ; Fang JINLI ; Si CHEN ; Luojia CHEN
Chinese Journal of Hospital Administration 2011;27(9):664-667
ObjectiveTo study the present human resources of TCM hospitals in China, for decision making of TCM hospitals HR strategy in the future. Methods Collection of statistics released by the Ministry of Health and the State Administration of Traditional Chinese Medicine from 2005 to 2009, for analysis of the general structure and trends of hospital staff at large, headcount and makeup of medical personnel, and the structure and trends of TCM professionals in TCM hospitals. Results In 2009, there were 2,728 TCM hospitals, employing 518, 5000 staff, including 427, 900 medical personnel, accounting for 82.52% of the total; TCM practitioners account for 45. 61% of clinicians in TCM hospitals;a shortage of nursesisfoundin TCM hospitals as comparedto general hospitals. ConclusionIt is imperative to revise the staff quota standard of TCM hospitals, and to increase the number of TCM practitioners and nursing staff in TCM hospitals.
10.Repetitive transcranial magnetic stimulation for post-stroke dysphagia:a systematic review of the literature
Ling LIU ; Haibo LIU ; Xiaoling WANG ; Li KONG ; Yongsheng GU ; Guanghui CHEN ; Fang YANG
Chinese Journal of Cerebrovascular Diseases 2014;(5):250-255,269
Objective To systematically review the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS)for post-stroke dysphagia. Methods The clinical trials about rTMS for post-stroke dysphagia were searched on Pubmed,EMbase,MEDLINE,Cochrane library,China National Knowledge Infrastructure (CNKI),Chinese BioMedical Literature Database on disc (CBMdisc),and Wanfang database with computers. Two independent reviewers selected the literatures by the inclusion and exclusion criteria,data extraction and cross-checking,and then conducted the analysis. Results A total of seven trails (228 patients,136 of them in a rTMS group and 92 in a control group)were included. Four randomized controlled trials (RCTs)were used for Meta-analysis (54 patients in the rTMS group,42 in the control group). The other three non-RCTs were only reviewed systematically. (1)Meta-analysis showed that the improvement of swallowing function score after rTMS was better than that of the control group (SMD=1. 73,95%CI 0. 45 to 3. 01;P=0. 008). (2)After high-frequency rTMS (>1 Hz),there was significant difference in the improvement of swallowing function score between the two groups (SMD=1. 60,95%CI 0. 10 to 3. 11;P=0. 04). Compared to the control group,there were also significant differences in the improvement of some swallowing function scores in low-frequency rTMS (1 Hz),suggesting the potential advantages of low-frequency therapy. (3)After rTMS,there was no significant difference in the improvement of Barthel index in patients with stroke compared with the control group (MD= -21. 60,95%CI-36. 21 to-7. 00;P=0. 004). (4)In terms of adverse reactions,seven trials did not report any adverse events, such as headache,tinnitus or epilepsy,etc. Conclusion Using rTMS may significantly promote the recovery of swallowing function for patients with post-stroke dysphagia,and it is both safe and effective.