0.05). Conclusion: There appears no clinical relationship between HBV and CAD.

Anticoagulants are recommended for the prevention and treatment of a wide variety of thromboembolic events.Although existing anticoagulants are effective,their usage is limited by parenteral administration or the requirement for frequent monitoring and subsequent dose adjustment.Therefore,there is an urgent need for novel,oral agents with a predictable anticoagulant action.Because of its key position in the coagulation cascade and its limited roles outside of coagulation,Factor Xa has presented as an attractive target for novel anticoagulants.As a result,the past decade has witnessed an explosion of research into small-molecule,oral,direct Factor Xa inhibitors,and some are now in clinical development.Rivaroxaban is currently furthest ahead in its developmental program,having entered phase III in 3 indications.It is hoped that,before long,these anticoagulants will allow us to enter an era of convenient,oral anticoagulation,without the need for regular monitoring or dose adjustment.

Objective To observe the therapeutic effect of Xuemeian Capsule for intermission of acute leukemia with bone marrow arrest after chemotherapy.Methods A prospective trial was carried out in 136 cases of acute leukemia after chemotherapy. The cases were randomly allocated to two groups.Group A(n=86)was treated with Xuemeian Capsule and routine western medicine and Group B(n=50)with routine western medicine.The changes of hemoglobin,platelet and leukocyte and the hyperplasia of bone marrow were observed.Results The totally effective rate was 93% and 54% in Group A and Group B respectively,the difference being significant(P

Objective: To explore the clinical value of four-dimensional ultrasound imaging in obstetric examination. Methods:Four-dimensional ultrasound was detected by V730 on 60 pregnant women who used ultrasonography in prenatal screening. Results:There were 60 cases in which 20 cases with limb malformation, 15 cases with facial deformity, 12 cases with spinal malformation, 8 cases with abdominal malformation, and 5 cases with chest malformation. Conclusion:Four-dimensional ultrasound can better dynamic observation of fetal surface malformations location, which can provide more worthy information for clinical diagnosis and treatment.

Objective To analyze the risk factors associated with respiratory dysfunction (ARD) in patients with DeBakey type Ⅰ aortic dissection after operation and provide the measures for prevention and treatment.Methods Retrospectively analyzed the clinical data of DeBakey Ⅰ type aortic dissection 18 patients under deep hypothermic cardiopulmonary bypass from September 2008 to March 2012 in the application of the three-branch type aortic arch endovascular stent.Recorded age,sex,preoperative complication,with or without perfusion badness syndrome,cardiopulmonary bypass time and aortic cross-clamping time.Monitoring preoperative and postoperative blood gas analysis,chest X-ray,ventilator parameters,intraoperative and postoperative blood transfusion.The single factor analysis of the risk factors associated with postoperative ARD was analyzed.Results No patient died in peroperative period.Five patients (27.8％) was in perfusion badness syndrome preoperative,8 patients (44.4％) was in ARD postoperative.Three patients (16.7％) occurred within 72 h and 5 patients (27.8％) occurred within 48 h.Three patients (16.7％) performed incision of tracheal for the duration of mechanical ventilation for more than 7 d.Correlation factor analysis showed that BMI (P =0.047),cireulatory arrest time (P =0.035) had correlation with postoperative ARD.Conclusions ARD is a common complication during perioperative.It can be correctable by pay full attention to the risk factors,and the prognosis is good.

Objective To investigate the correlation between glycosylated hemoglobin(HbAlc),plasma NTproBNP and the cardiac function in patients with acute coronary syndrome(ACS).Methods 53 patients with both ACS and type 2 diabetes mellitus(T2DM)(T2DM group),67 patients with ACS(ACS group)were selected as the objects.The HbAlc level was detected by immunohistochemical than turbidimetry,and the content of NT-proBNP was detected by electrochemiluminescence method.Results The levels of HbAlc,plasma NT-proBNP of the T2DM group were(9.21±1.23)％,(3.56±1.12)ng/ml,respectively,which were higher than those of ACS group[(5.09±0.67)％,(0.14±0.04)ng/ml](t=6.495,9.277,all P＜0.01);The cardiac function of ACS patients was positively correlated with the levels of HbA1c and plasma NT-proBNP(r=0.517,0.589,all P＜0.01),and there was positive correlation between the levels of HbAlc and plasma NT-proBNP in ACS patients(r=0.431,P＜0.05).Conclusion The HbAlc and NT-proBNP can promote the injury of the cardiac function of ACS patients,and can be used as diagnostic indicators of the injury of the cardiac function of ACS patients.

Objective To study the effect of Shenjinhuoxue decoction in treating cervical spine.Methods 134cases of patients with cervical spine were randomly divided into two groups:control group(n=62)and therapy group (n=72).The control group were treated with normal method of Jingfukang particles.The therapy group were treated with normal method and Shenjinhuoxue decoction for cervical spine.The total effective rate and the side action was compared.Results After a period of treatment,the treatment group healed 38 cases,excellence 24 cases,effective 10cases,invalid 0 case,total effective rate Was 100.0%,control group healed 10 cases,excellence 16 cases,effective 28cases,invalid 8 cases,effective rate was 87.1%.Compared with the control group,effective rate and healing rate in therapy group were increased obviously(x2=7.715,P＜0.01).Conclusion Shenjinhuoxue decoction was safe and effective in the treatment of cervical spondylosis.

Sentinel lymph node biopsy represents the state of the art of breast surgery, but its widely application might surpass the support of available evidences. The hot spots of sentinel lymph node biopsy in breast cancer include the prognosis of micrometastases in sentinel nodes, the prediction of non-sentinel nodes metastases in positive sentinel nodes patients, and the intraoperative molecular diagnosis of sentinel nodes.These are discussed accompanying with the updated results from the 31st SABCS held in December, 2008.

Objective To set up a method for extracting and purifying of flavonoids in Dried Tangerine peel.Methods Total flavonids being used as an index, UV spectrophotometer was used to optimize the extracting technology with the help of orthogonal experiment. Meanwhile macroporous resin was adopted for optimizing indexes of total flavonoids.Results The optimum conditions for purification were as followings: AB-8 macroporous resin, 50% of ethanol serving as eluting solvent, 0.4g/mL of sample concentration, 1:5 ration of diameter to height, 2BV/h of current velocity, and 5BV of flow column. Conclusion The content of total flavonoids was remarkably increased after purification.

Objective : To investigate the effects of Mini-SG~ F attachment on periodontal health of the abutment teeth in restoring free-end removable partial dentures (RPDs). Methods : The periodontal status of the abutments in restoring free-end RPDs was longitudinally observed with periodontal indices commonly used in clinics, and a group comparison was made using a one-way analysis of variance (ANOVA). Results: The stability and retention of free-end RPDs retained by Mini-SG~ F attachments were excellent during the whole observation course. Compared with the periodontal status of the first and the second abutments before restoration respectively, no significant differences in gingival indices, plaque indices, periodontal probing depth, alveolar bone resorption levels of those were shown 6 months after restoration. The mobility of the abutments was significantly reduced when they were splinted together. Conclusion: Mini-SG~ F attachments used in free-end RPDs have no evident adverse effect on periodontal health of the abutment teeth, and the way of splinting the abutments is advantageous to their long-term health and stability.