Body weight support treadmill training (BWSTT) is introduced in this paper as a new rehabilitation training approach, which is effective for hemiplegic and paraplegic patients. The appraisals of the famous foreign experts in rehabilitation for BWSTT are also reviewed.

The efficacy of physical therapy for cerebral infarction is outstanding. This paper is to introduce that if physical therapy is combined with NA-gic drug-d-amphetamine,the latter will promote recovery of motor function in stroke patients. D-amphetamine can also enhance recovery from aphasia and poor motivation syndrome in patients after ischemic stroke. The recovery of hemiplegia in strok patient after treatment of d-amphetamine is proposed owing to dispel inhibition in the contralateral cerebellar hemisphere. This corresponds to the concept of diachisis.

Motor function is the main function of human being takes place the social activities in the world. Unfortunately, regardless of either CNS or PNS injury, the outcome usually is paralysis. Up to date there is still no drug may restore the function of paralyzed limbs rapidly, completely and satisfactorily. However, the scientist have used drugs to enhance motor function recovery after brain injury and got some effects since the mid of past century, e.g. the amphetamine. The function of amphetamine, notwithstanding was denied by Veterans Affairs/Department of Defense Clinical Practice Guideline for the Management of Adult Stroke Rehabilitation Care in 2005, however, there were other reports concerning with same purpose study, that may facilitate the recovery of motor function, e.g. Fluoxetine, Selegiline, L-dopa and so on. In the meantime, there also found some drugs with opposite effect and slowing the functional recovery, e.g., Haloperidol, Prazosin, Phenytoin and so forth.

The cognitive function of brain is very comprehensive, memory and attention are their constituent. How to enhance the recovery of cognition after injury of brain now is the important duty of rehabilitation pharmacology. This paper will introduce the common drugs which may facilitate the recovery of memory, attention after injury of the brain.

Agitation, aggression and depression are frequent neurobehavioral sequalae after injury of brain. These behavioural symptoms disrupted patient care and impede rehabilitation effort. In severe cases, the patient even hurts others and sometime injuries himself. This article introduces the use of antipsychotics, mood stablizing, lithium, antianxiety medication and antidepressants especially the SSRIs for the emotion disturbance after injury of brain. Meantime, paper describes the 5-HT syndrome, withdrawal 5-HT syndrome, the neuroleptic malignant syndrome (NMS). The later is owing to wrong use of phenothiazines and butyrophenones. The mortality of NMS is about 25%, if case treats is not correct.

ObjectiveTo study the effect of rehabilitation treatment on diffuse axonal injury(DAI).Methods24 inpatients with DAI were performed a 3 month rehabilitation program.Before and after rehabilitation treatment,evaluation of locomotion function, walking ability,activities of daily living(ADL) and cognitive ability were performed and compared with each other.ResultsThe hand function showed no distinct change(P>0.05), while the locomotion function of upper limb was improved significantly(P<0.05), and that of lower limb was improved more significantly (P<0.01) as while as the walking ability.ADL and cognitive ability were improved very more significantly (P<0.001).ConclusionsIntegrative rehabilitation treatment cannot significantly improve the hand function of patients with DAI, but can significantly improve the locomotion function of upper and lower limb,ADL and cognitive ability.

Objective To observe the effect of ankle foot orthoses (AFO) on improving the abnormal gait pattern in hemiparetic patients Methods 106 hemiparetic patients were randomly divided into two groups. AFO was used in one group (52 cases) and not in the control group (54 cases). Both of them accepted conventional physical therapy. Motor function of affected ankle joint and lower extremities, spastic state of ankle joint, standing balance and walking ability were evaluated on each case before and after rehabilitation Results At the end of the trial, spastic state of ankle joint in both groups were decreased. 40 cases reached to degree of ⅠorⅠ + of spastic state and 12 cases to Ⅱ, Ⅲ or Ⅳ in the AFO used group,while the number of cases in the control group were respectively 27 and 27. The effects in AFO used group showed more significant than in the control group ( P 0.05) Conclusion Physical therapy combined with ankle foot orthoses was beneficial to improving the abnormal gait pattern and decreasing the spastic state of ankle joint in hemiparetic patients. However, it might not affect the motor function of ankle joint and lower extremities.

This article introduced the form of the rehabilitation evaluation discussion, which was moderated by the rehabilitation doctors, together with relevant therapists and nurses, aiming to discuss the obstacles and the rehabilitation plan for a difficult patient. This case showed the importance of early rehabilitation after stroke.

ObjectiveTo explore the pathogeny, diagnosis and rehabilitation of central pontine myelinolysis.MethodsClinical data of four patients with central potine myelinolysis were studied retrospectively.ResultsAll of them had pseudobulbar palsy and dystonia; three had coma; two had history of hyposodemia ameliorated rapidly, one had history of hypersodemia ameliorated rapidly. All of them had focuses in pons; three had focuses beyond pons. All patients had good prognoses.ConclusionHistory of hyposodemia ameliorated rapidly is a usual pathogeny of central potine myelinolysis, integrative measures of rehabilitation can improve prognosis and quality of daily life.

Objective To investigate the differential expression levels and significance of regulatory T cell (Treg) and T helper 17 (Th17) related immunologic factors in peripheral blood of arsenic-exposed rats.Methods Thirty-two Wistar rats were numbered by weight,randomly divided into four groups [control,low (1.25 ml/kg),medium (2.50 ml/kg),and high (5.00 ml/kg)],8 rats per group.Rats in control group were given oral gavage of deionized water,and low,medium and high arsenic exposed groups were given oral gavage doses of 2.00 g/L sodium arsenite (NaAsO2) according to their body weight for 6 days every week.After 4 months,the urine and peripheral blood samples of rats were collected,urinary arsenic (uAs) was detected by inductively coupled plasma-mass spectrometry (ICP-MS),the results were shown in [median (minimum and maximum)],uAs was corrected by urinary creatinine (uCr),the unit was μg/g Cr;enzyme-linked immune-sorbent assay (ELISA) was applied to detect the levels of Treg,Th17,T lymphocytes activation related immunologic factors [interleukin-10 (IL-10),transforming growth factor beta1 (TGF-31),IL-17,IL-6,IL-2],the results were shown in (x) ± s.Results The uAs of the rats was compared between control,low,medium,and high arsenic exposed groups [7.50 (3.16-9.81),72.34 (62.34-106.63),209.15 (154.41-232.20),369.73 (289.50-516.55) μg/g Cr],the differences were statistically significant (F =337.55,P ＜ 0.05).IL-10 [(85.03 ± 7.11),(93.96 ± 8.14),(97.48 ± 6.23),(93.47 ± 4.41) ng/L],TGF-β1 [(72.88 ± 2.96),(81.45 ± 8.15),(86.08 ± 7.55),(90.29 ± 5.35) ng/L],IL-17 [(18.15 ± 3.66),(25.54 ± 5.59),(31.48 ± 5.74),(37.25 ± 7.36) ng/L],IL-6 [(83.68 ± 8.48),(85.14 ± 7.11),(89.78 ± 5.36),(93.48 ± 5.77) ng/L],and IL-2 [(80.65 ± 6.90),(73.86 ± 8.00),(69.93 ± 7.77),(62.06 ± 9.82) ng/L] of the rats were compared between control,low,medium,and high arsenic exposed groups,the differences were statistically significant (F =5.094,11.054,16.249,3.474,5.119,all P ＜ 0.05).There were positive correlations between uAs and TGF-β1,IL-17 concentration (r =0.723,0.605,all P ＜ 0.01),while IL-2 showed a negative correlation (r =-0.484,P ＜ 0.05).Concltsion Arsenic exposure could affect the secretion of Treg and Th17 related immunologic factors,so as to the imbalance of anti-inflammatory and pro-inflammatory,which may play a role in the formation and development of arsenic-related immune injury.