Teachers develop integrated experiments on nursing management in laboratory center of nursing teaching. By using the methods of imitation and role-play,students exercise nursing management theories and skills that they have learnt to digest related knowledge. In this way,teachers train the students'comprehensive capabilities of communication and coordination,creative thinking,parsing and solving questions and improve the outcome of teaching practice on nursing management to provide clues for more and better integrated experiments.

Objective:To examine the potential hemispheric asymmetry of conflict control in two subtypes of children with ADHD(25 of predominantly inattentive,i.e.,ADHD-I;and 31 of combined,i.e.,ADHD-C).Methods:A cross-modal interference task was used,in which the auditory distractors were provided either from the left ear or from the right ear and they constituted congruent,incongruent or neural relations with targets displayed at the screen center of the computer.Results:Children with ADHD showed an distinctive pattern of error rate when distractors were provided from the left ear compared with the normal controls,with a significant conflict effect for ADHD(effect size was 4%),F(1,110)=18.16,P0.1.Moreover,children with ADHD showed a tendency of a reversal inhibition effect(effect size was-1.7%),F(1,110)=3.16,0.050.1.Conclusion:The results suggest that children with ADHD showed atypical pattern of their right hemisphere in conflict control compared with normal children,the atypical pattern of right hemisphere for ADHD-C need to be further studied.

0 05) Conclusions Cervical epidural for postoperative analgesia can effectively inhibit the stress response in patient after the replantation of amputated fingers but dose not affect respiratory function Fentanyl provides best analgesia with less adverse effects and is suitable for postoperative analgesia in these patients

Objective To optimize the formulation of the Garlic oil ?-CD sustained-release tablet. Methods The preparation formulation of the sustained-release tablet was optimized by orthogonal design which took the released rate as the index. Result The optimized formulation contained 9% HPMC, 15% lactose, 10% PVP, 10% microcrystalline cellulose. The ingredient of Garlic oil sustained-release tablet by this formulation was released slowly in 8 h. Conclusion The optimized formulation is rational and stable, the tablet could be released slowly.

Objective To establish a method of HPLC gradient elution method determination of Notoginsenoside R1, Ginsenoside Rg1 and Rb1 in Naodesheng Capsules. Methods Kromasil C18 column was used with a mobile phase of acetonitrile-water gradient elution, column temperature at 25 ℃. Results Notoginsenoside R1, Ginsenoside Rb1 and Ginsenoside Rg1 showed good linear relationship at the range of 0.495～1.782 ?g (r =0.9999), 2.65～9.54 ?g (r =0.9995), 1.85～6.66 ?g (r =0.9999), respectively. The average recovery:Notoginsenoside R1 was 100.60% (RSD=1.99%), Ginsenoside Rb1 was 100.86% (RSD=2.19%) and Ginsenoside Rg1 was 98.83% (RSD=1.95%), respectively. Conclusion The methods is simple, accurate, highly sensitive and reproducible. It can be used for the quantitative determination of Notoginsenoside R1, Ginsenoside Rg1 and Rb1 in Naodesheng Capsules.

[Objective] To evaluate the treatment effect of the synovial chondromatosis of the hip through arthroscopy,and to describe the arthroscopic classification.[Methods]From March 2001 to May 2008,21 patients underwent arthroscopic management for primary synovial chondromatosis of the hip.Of the 21 patients,15 were male and 6 were female,aged from 17 to 49 years.The disease was located on the left side in 9 patients,the right side in 12.Anterior and anteriolateral approaches were selected for synovectomy and removal of free bodies.The peripheral compartment received traction,and curved scraper and Slide Winder Blade(the bending radio frequency)were used to deal with the acetabular fossa.[Results]The range of motion of the hip was improved and the pain was released after operation.MRI showed hydrops articuli was reduced or vanished.Harris hip score for the series of patients improved from 56.2 points preoperatively to 92 points at the mean follow-up of 45 months(11 to 96).Of the 21 patients,18(85.7%)had excellent or good outcomes.No recurrent case was found.[Conclusion]Hip arthroscopy proved beneficial for patients diagnosed with synovial chondromatosis of the hip.It had the advantages of minimal invasion,quick recover and satisfactory outcomes.Arthroscopic classification may guide the procedure and avoid omision of the free bodies.

Objective Inflammation is considered as a driving force in the pathogenesis of Alzheimer's disease. We study the inhibitory effects of indomethacin on production of nitric oxide (NO) in ?-amyloid 1-42 stimulated microglia in vitro, in order to explore the role of ?-amyloid and microglia in the pathogenesis of Alzheimer's disease, and that admimistration of anti-inflammatory drugs might be an effective therapeutic modality. Methods We cultured murine microglia BV-2 cells to serve as the model of microglia for experimentation in vitro. Indomethacin in different concentrations (10 -9 , 10 -8 , 10 -7 , 10 -6 and 10 -5 mol/L) was added separately without or with ?-amyloid 1-42 20?mol/L, and culture was continued for 12h. The production of nitric oxide (NO) and the activity of inducible nitric oxide synthase (iNOS) in the supernatant of culture were determined. iNOS mRNA expression was assessed by RT-PCR. Results There was no effect in the production of NO and the activity of iNOS in BV-2 cells incubated with indomethacin alone. Indomethacin could inhibit NO production and lower iNOS activity and iNOS mRNA expression after microglia were stimulated by ?-amyloid 1-42, and the inhibitory effect was obvious at the concentration of 10 -7 -10 -5 mol/L. Conclusions As a conventional non-steroidal anti-inflammatory drug (NSAIDs), indomethacin can inhibit NO production, decrease iNOS activity and iNOS mRNA expression in BV-2 microglia after being stimulated by ?-amyloid 1-42 in vitro. The results suggest that the mechanism by which indomethacin might be beneficial in treatment of AD might be due to the inhibition of NO production from microglia, blocking the inflammatory cascade reaction to ameliorate injury to neuron. As an effective model in vitro, BV-2 microglia are valuable in the study of Alzheimer's disease.

Objective To investigate the effect of nursing rescue process on traffic accident aid to orthopedic patients . Methods Sixty patients with bone injuries from traffic accidents during April to December 2013 were set as control group , in which the traditional aid process was used for rescue, and another 60 patients during January to June 2014 as experiment group, in which the nursing aid process was applied. The two groups were compared in terms of rescue time and effectiveness. Result The rescue time in the experiment group was significantly shorter and the first aid effectiveness was also better than those in control group (P<0.01). Conclusion By nursing aid process, the personnel can be optimized to avoid chaos during the rescue and meanwhile the time for rescue is shortened, which can contribute the increased success rate.

Objective To establish a determination method of Allicin in Garlic oil Sustained-release Tablets. Method Diamonsil C18 column was used with a mobile phase of mathanol-water-formic acid (80∶20∶0.1). The detective wavelength was at 218 nm. The flow rate was 1.0 mL/min. Column temperature was at 25 ℃. Results Allicin showed a good linear relationship at the range of 0.05～0.25 ?g (r=0.999 9). The average recovery rate was 99.5% (RSD=1.7%). Conclusion The method is simple, accurate, highly sensitive and reproducible. It can be used for the quantitative determination of Allicin in Garlic oil Sustained-release Tablets.

Objective: To explore the role of corticosterone in morphine-induced acute psychomotor activity and behavioral sensitization.Methods: 32 male SD rats were divided into four groups. Rats were intraperitoneally given saline, morphine, corticosterone and corticosterone/morphine separately. The horizontal locomotor activity was recorded for 60min by the computer trace system automatically. The locomotor activity was measured in every two days for total seven times. Results:The corticosterone/morphine group showed significant morphine-induced acute psychomotor effect comparing with the saline group(saline group 7175?676, corticosterone/morphine group 10365?503,P