Objective To evaluate the diagnostic value of three-dimensional CT(3DCT)in atlantoaxial lesions.Methods The findings of 3DCT were analyzed and compared with conventional CT and radiography in 124 patients with atlantoaxial disease.Results 124 cases of atlantoaxial lesion included fracture in 42,atlantoaxial rotatory dislocation in 73,hypoplasia of the dens in 4,and congenital atlantoaxial deformity in 5.Among the 124 cases,89 cases were diagnosed by X-ray,109 cases by conventional CT,121 cases by MIP,122 cases by SSD,124 cases by MPR and VR.Conclusion 3DCT can find the slight rotatory dislocation,so it is the most effective means for the diagnosis of atlantoaxial rotatory dislocation.3D and MPR of spiral CT are useful in the diagnosis of atantoaxial fracture.Combining conventional CT and X-ray film with 3DCT can improve the acuracy of the diagnosis.

Objective: To develop the national norms of ISCA (intelligence scale for Chinese adult) for urban adults aged 16 to 64 years and examine its psychometric characteristics. Methods:The ISCA standardization was completed on 1600 adult subjects. Year 2000 Census data was applied to the standardization sample in order to correctly represent individuals by age, gender, educational level, geographic region, and occupation. Results:The ISCA had good reliability( test-retest coefficients of Full scale IQ was 0.96, the average spilt-half reliability for the IQ scales ranged from 0.93 to 0.96 and the average standard error of measurement of subtest ranged from 1.04~1.88, rater reliability 0.91~0.96). The total score of ISCA relates that of the WAIS-RC, WAIS-III revised in Taiwan, and CRT-C2 are 0.94, 0.90, 0.69, respectively (P

Objective To observe the effects of indole-3-carbinol on neointimal hyperplasia and restenosis of rat artery after balloon injury and the possible mechanisms.Methods Balloon dilation was used to establish the neointimal injury model of left carotid artery in rats.Twenty Sprague-Dawley rats were randomly divided into single balloon dilation group(control group)and balloon dilation followed by indole-3-carbinol therapy group(therapeutic group).After balloon dilation,indole-3-carbinol(12.5,25,50 mg/d)was applied to the rats for 7 days respectively.The rats were killed two weeks after balloon dilation and the injured vascular specimens were harvested for pathologic examination and immunohistochemical staining.Results ①The neointimal thickness,neointimal area in the therapeutic groups were significantly less than that of the control group(P

Objective To explore the application value of D-dimmer(DD),hs-CRP and homocysteine(Hcy) in postoperative condition monitoring in the patients with femoral neck fracture.Methods Forty cases of femoral neck fracture treated in our hospital were selected as the observation group and 40 patients with other fractures were selected as the control group.The observation group were given the surgical treatment,while the control group adopted the corresponding measures for conducting intervention according to the fracture situation.The DD,hs-CRP and Hcy levels were detected in the two groups.Then the detection results were compared between the two groups.Results The various indexes before treatment in the observation group were slightly higher than those in the control group without statistical difference(P>0.05).The levels of various indicators at postoperative 24,48 h in the observation group were significantly elevated,moreover the increase range at postoperative 24 h in the observation group was maximal,which was significantly higher than that in the control group(P<0.05).The positive rates of hs CRP,Hcy and DD in the observation group were 75.00%,77.50% and 60.00% respectively,while which in the control group were 0.00%,2.50% and 0.00%,the observation group was significantly higher than the control group (P<0.05).Conclusion Hs CRP,Hcy and DD can be used as the important indicators of condition monitoring for femoral neck fracture.

Objective To explore the effect of SZ-685C on rat pituitary adenoma GH3 cell line.Methods MTT method evaluated its effect of proliferation and inhibitory concentration 50 (IC5o) on GH3 cells,after treated by 0,2.5,5.0,7.5,10.0,12.5,15.0,17.5,20.0 and 30.0 μmol/L SZ-685C for 48 h,GH3 cells were changed to complete medium for 12 d,crystal violet staining was used to investigate colony formation; microscopy and Hoechst 33342 staining assay observed whether the changes of morphological as the result of apoptosis,then detected cell apoptosis by flow cytometry.Results SZ-685C had a dose-dependent inhibitory effect on GH3 cell proliferation and IC50 was (12.9 ± 0.47) μmol/L,MEF(considered as a control group) had little affect in cell proliferation on the concentration of IC50.Inhibitory effects persisted even on removal of SZ- 685C after 12 d,and SZ-685C blocked colony formation ability of pituitary tumor cells.Apoptotic morphological observation of microscope and Hoechst 33342 staining proved apoptosis during treatment of SZ-685C,flow cytometry detection showed that SZ-685C induces 36.4％ of apoptosis,while only 2.0％ in control group.Conclusion SZ-685C inhibits pituitary tumor cell proliferation and induces apoptosis.SZ-685C can be a new anti-patuitary tumor drug for a further study.

BACKGROUND:Data suggested that there were 24.5 million of human immunodeficiency virus (HIV) infected women in 16 countries in southern Sahara Africa.OBJECTIVE: To survey the HIV infection status among women in reproductive age in Mauritania so as to provide research direction and basic data for prevention and treatment of immunodeficiency diseases.DESIGN: Random sampling survey.SETTING: Epidemic Disease & Health Statistics Department of Radiation Medicine and Public Health College of Suzhou University;Institute of Iodin Absence of Harbin Medical University;and Public Health College and Epidemic Disease & Health Statistics Department of Harbin Medical University.PARTICIPANTS:The survey was conducted in the 14 main cities of the whole country from March to June 2001. Inclusion criteria: Women were in reproductive age, aged 15-49 years, from Mauritania; and all told the fact.Exclusion criteria: Women refused survey and not in reproductive age were excluded.Among 331 548 women,4 000-6 000 samples were surveyed and the sampling rate was 1.2％-1.8％.METHODS: Venous blood and isolated sera of women in reproductive age were collected. Sera were detected by ELISA test and confirmed by Western Blot test in order to know HIV infection and its subtypes.The detection rates of different population and cities were calculated and made statistical analysis.MAIN OUTCOME MEASURES: The infection and subtypes of HIV; infected rate of HIV among different crowd in different cities.RESULTS: Among 4 648 women in reproductive age in 13 provinces, 24infected cases aged of 15-49 years were found with the infected rate of 0.516％,of them 22 cases were infected with HIV-1 and 2 cases were in fected with HIV-2. The detection rates were 0.500％-1.010％ (5 cities), 0-0.500％ (3 cities) and 0％ (5 ities) respectively. The age of 95.83％ of the total infected cases was 15-29 years. The number of the HIV-infected cases was about 1 400 persons among women in reproductive age in 13 main cities.CONCLUSION: The total HIV-infected detection rate was 0.516％ among women in reproductive age in 13 main cities of Mauritania.HIV-1 2 was the dominant subtype. HIV infection was different among regions. HIV-in fected cases aged 15-29 constituted more than 95％ of the total cases. The prevalent trend of AIDS was in the stage of transmission after importing.

Objective To study multi-slice spiral CT(MSCT) manifestations of spondyloschisis.Methods 40 patients with spondyloschisis were examined with MSCT scan and 3D reconstruction.Results In the 40 cases,CT scans showed spondyloschisis of the lumbar in L_2(1/40),L_3(1/40),L_4(10/40),L_5 spondyloschisis of the lumbar in L_2(1/40),L_3(1/40),L_4(10/10),L_5(28/40).MSCT displayed:the ring-scission sign(100%),the pseudo-bulging of lumbar intervertebral disc and the elongated sign of spinal canal(95%),and the wavered sign of vertebral body(12.5%).The location,shape of spondyloschisis and the degree of spondylolisthesis were demonstrated by MSCT on multiplanar and 3D.Conclusion The ring-scission sign is the specific sign in diagnosing the spondyloschisis of the lumbar by MSCT.It is of significant value in the detection of spondyloschisis

Objective To investigate the value of CT pulmonary artery obstruction index (PAOI)in evaluating the severity in patients of pulmonary embolism (PE)by a correlation study between CT PAOI and right ventricular function parameters and arterial blood gas analysis index.Methods CT PAOI,right ventricular function parameters and arterial blood gas analysis index were collected from 70 patients with PE,who had received CT pulmonary angiography (CTPA)examination in our hospital.Spearman rank correlation coefficient was used to evaluate the correlation between the PAOI and right ventricular/left ventricular maximum short axis diameter ratio (RVd/LVd),main pulmonary artery diameter (MPAd),superior vena cava diameter (SVCd),arterial oxygen partial pressure (PaO2 ),arterial carbon dioxide into pressure (PaCO2 ),oxygen saturation (SaO2 ),Alveolar arterial oxygen partial pressure difference (P(A-a)O2 ).Results PAOI and PaO2 were negative correlation,the correlation coefficient was -0.442;PAOI and RVd/LVd, MPAd,SVCd,P(A-a)O2 were positively related,correlation coefficients ranged between 0.163-0.675;PAOI was not related to SaO2 .Conclusion CT PAOI can be used to evaluate the severity of PE,it is not consistent with the severity of the patient’s clinical condition.

Objective: To explore early diagnostic and resent prognostic assessment value of serum levels of ischemia-modified albumin (IMA) and cardiac troponin I (cTnI) for acute coronary syndrome (ACS).Methods: A total of 175 ACS patients were selected, including 73 cases with unstable angina pectoris (UAP), 61 cases with non-ST elevation myocardial infarction (NSTEMI) and 41 cases with ST elevation myocardial infarction (STEMI).According to chest pain-to-visit time, ACS patients were divided into <3h group (n=112) and 3~6h group (n=63);another 40 healthy subjects were selected simultaneously as healthy control group.Serum IMA and cTnI levels were compared among above groups and between patients suffering from major adverse cardiovascular events (MACE) within 30d or not in <3h group.Risk factors for MACE in <3h patients within 30d were screened.Results: Compared with healthy control group and UAP group, there were significant rise in serum levels of IMA[(16.78±4.25) μg/L, (35.16±8.32) μg/L vs.(49.76±9.29) μg/L, (52.07±11.34) μg/L], cTnI[(0.17±0.06) ng/ml, (0.15±0.06) ng/ml vs.(7.65±1.29) ng/ml, (8.83±1.40) ng/ml]in NSTEMI group and STEMI group, and IMA level in STEMI group was significantly higher than that of NSTEMI group, that of UAP group was significantly higher than that of healthy control group (P<0.05 or <0.01);serum IMA level of <3h group was significantly higher than those of 3~6h group and healthy control group, and cTnI level of <3h group was significantly lower than that of 3~6h group (P<0.01 all);serum levels of cTnI and IMA in patients suffering from MACE in <3h group were significantly higher than those of patients without MACE (P<0.01 both);multi-factor Logistic regression analysis indicated that elevated serum IMA level was an independent risk factor for MACE within 30d in ACS patients[OR=2.757,95%CI(2.084~4.705), P=0.001].Conclusion: The levels of cTnI and IMA significantly rise in ACS patients.IMA level possesses early diagnosis and recent prognosis evaluation value.