This article introduces a cerebral thrombus protection device for the cerebral interventional treatment, also introduces the principle, design and manufacturing process of the device, and confirmes the effectiveness in vitro experiment.
Equipment Design ; Humans ; Thrombosis ; prevention & control

Objective To investigate the utility of combined detection of procalcitonin(PCT ) ,C‐reactive protein(CRP)and preal‐bumin(PA)in elderly patients with acute respiratory infectious diseases .Methods Detected the serum procalcitonin(PCT) ,C‐reac‐tive protein(CRP) and prealbumin(PA) of 110 elderly patients with acute respiratory infectious diseases and 40 healthy people dur‐ing the same period as control group .The levels of PCT and CRP and PA among groups were compared before and after treatment . The 110 elderly patients with acute respiratory infections were divided into into bacterial infection group(n= 40) ,virus infected group(n=34) and mixed infection group (n=36) according to the pathogen type .Results Before treatment ,the PCT and CRP of bacterial infection group and mixed infection group were significantly higher than that of control group ,while the level of PA was lower ,and the difference were statistically significant(P<0 .01) .When Viral infection group compared with the control group ,all the indicators showed no significant difference(P>0 .05) .After treatment ,there was no significant difference .The sensitivity ,spe‐cificity ,accuracy ,positive predictive value ,negative predictive value ,and Youden′s index of combined detection of the three indica‐tors were higher than those of single detection in acute respiratory infection .Conclusion PCT ,CRP and PA can be used as the di‐agnostic indexes for elderly patients with acute respiratory tract infection .The combined detection of the 3 indexes can improve the accuracy of early diagnosis of acute respiratory tract infections in elderly patients and can be used in therapeutic efficiency evalua‐tion .

The mechanism of thrombus formation in living vessel wall is complex and involves a combination of blood and vessel wall properties and local flow conditions.The significance，theory and experimental tech-niques of thrombus formation in vivo were comprehensively reviewed.Particularly,the important role of signa-ling pathway and hemodynamic in thrombus formation in vivo was pointed out.The difficulty ic in vivo animal models was analyzed.Some recent new phenomena as welt as new approaches and directions worthy of in-vestigation also were summarized.

OBJECTIVE: To evaluate the preemptive analgesia effects of both the parecoxib sodium and the pentazocine in patients undergoing nasal endoscopic surgery. METHOD: In the randomized, double blind, controlled study, 120 patients undergoing septoplasty were divided into 3 groups (n = 40): group A received parecoxib 40 mg by muscle injection 30 min before the operation; group B received pentazocine 30 mg; group C received an equal volume of saline. The preemptive analgesia effect was evaluated with VAS scores which recorded at different time points. The proportion of participants using rescue analgesia after the operation were recorded as additional measures of preemptive analgesia. RESULT: Intra-operative as well as the postoperative pain scores were less in the group A and group B than in the control group. Fewer participants required rescue medication after operation with parecoxib as well as pentazocine than placebo. However there were no difference in the preemptive effects between the group A and group B. CONCLUSION Administration of both the parecoxib and pentazocine before the nasal endoscopic surgery can provide preemptive analgesia without serious adverse side effects that deserves popularization in the clinic.
Analgesia ; methods ; Analgesics ; therapeutic use ; Double-Blind Method ; Endoscopy ; adverse effects ; Humans ; Isoxazoles ; therapeutic use ; Nasal Surgical Procedures ; adverse effects ; Nose ; Pain ; prevention & control ; Pain, Postoperative ; prevention & control ; Pentazocine ; therapeutic use

The management of medical equipment is a difficult part of health works for CPAPF'smobile health institutions,and it restricts the development of health institutions in a certain extent.So in order to do it well,this paper puts forward some countermeasures for the existing new problems in the management of medical equipment of CPAPF's mobile forces,whose aim is to enhance the ability of medical support for CPAPF's mobile forces.

Objective: To study the effect of antidepressant in treatment of patients with PSD (post-stroke depression) Method: 121 patients with PSD in their rehabilitation period were stratified by results of HAMD and then randomly divided into two groups, the study group (n=64) received Paroxetine 20 mg daily, the control group (n=57) received placebo After 4 months, the result was assessed with HAMD, CSS and ADL (activity of daily living) Result: In the period of rehabilitation of stroke, the degree of neurological impairment (CSS score) was positively correlated to depression (r=0 99, P

Objective To analysis the time of acute cerebral stroke occurrence. Methods The occurrence time of 2675 patients with cerebral infarction (1925 cases,CI group) and intracerebral hemorrhage(750 cases,ICH group) were statisticed by 1 time unit per 2 h from 0∶00. Results There was a time-curve with double peaks of stroke occurrence,like as circadian rhythms of blood pressure in 24 h. ⑴ In CI group,the first peak was 6∶00~10∶00, the second peak was 18∶00~22∶00. The value of the first peak was higher than that of the second(P

In this study, we applied in vivo electroporation(EP) for HBV DNA vaccine administration to improve the cell transfection rate of plasmid DNA and to enhance the immune response. In BALB/c mice (8 mice in each group), the luciferase activity (16170?12533RLU) was 4 digits higher than that of the non EP control (8 02?8 00RLU), the difference between them was very significant ( P

Objective To investigate the expression, relationship, significance of cyclooxygenase_2 (COX-2) and malonic dialdehyde (MDA) after cerebral ischemic-reperfusion injury and provide basis of treatment. Methods The focal cerebral ischemic-reperfusion model was established with thread embolish of middle cerebral artery. Western blotting, barhituric acid method and neurological evaluation were used to examine the expression of COX-2, MDA in cortex and the changes of neurological function;TTC staining was used to observe the changes of cerebral infarction volume. Results COX-2 prorein expression was correclated well with the MDA(r=0.910,P＜0.01). The content of COX-2 and MDA was very low in sham operation group, they were increased significantly at I2h/R6h model group, with the increase of reperfusion time,they remarkably reached its peak at I2h/R24h,they were slightly lower at I2h/R48h, but still maintained at a high level;Compared with model group, in tetramethylpyrazine(TMP) treatment group, the content of MDA and cerebral infarction volume were markedly decreased(P＜0.01). Conclusion The expression of COX-2 and MDA increases in cerebral ischemic-reperfusion injury.It indicates they may play an important role in the mechanisms of cerebral ischemic-reperfusion injury;TMP has neuroprotective effect.

Objective To discuss clinical characteristics and surgical treatment of patients with pulmo?nary inflammatory myofibroblastic tumor(PIMT). Methods From April 2010 to June 2015 in Beijing Tiantan Hospital Affiliated to Capital Medical University, there were 15 cases patients diagnosed as PIMT and trea?ted. The clinical datas of the patients were analyzed retrospectively. The main clinical manifestations,pathological results,clinical treatment and prognosis of the patients and follow?up outcome were analyzed. Results There were 10 males and 5 females,at the age of 39 to 6 8 years old with the median age of 52. Among the 15 cases of patients with PIMT,1 case was recurrence,14 cases were initial treatment. The treatment reason was due to the abnormal physical examination,or cough and sputum with blood,or chest pain,or chest tightness or fever. Chest CT showed that the mass was round or class round, lobulated, part of them showed the burr shape edge. Immunohistochemistry showed that Vimentin positive and smooth muscle actin positive. All patients accept?ed the open chest or thoracoscope surgery. The main operations concluded partial resection,lobectomy or lobecto?my with lymph node eradication. No perioperative death occured,no complications such as postoperative bleed?ing,bronchial pleural fistula and other complications happened. The average follow?up time was from 8 to 58 months. Follow?up rate was 100. 0%(15/15). There was no tumor recurrence. Conclusion The clinical mani?festations of the pulmonary inflammatory myofibroblastic tumor is complex. The PIMT should be confirmed by pathologic examination,the main treatment is surgical resection with good prognosis and lower recurrence.