1.Surgical treatment of long bone fracture caused by high energy trauma
Yongdong MA ; Wenmao LIN ; Qunzhou REN
Orthopedic Journal of China 2006;0(02):-
0.05).Satisfactory results can still be possible if suitable fixation,adequate external immobilizaiton and rational rehabilitation measures were choosed case by case according to the different fracture types and impaired soft tissue.
2.Effects of furoic acid mometasone nasal spray on pediatric sinusitis patients
Yongdong LIN ; Hanzhong DUAN ; Li XIA
Chinese Journal of Primary Medicine and Pharmacy 2015;(7):1038-1040
Objective To study the effects of the pediatric sinusitis patients using furoic acid momethasone nasal spray after the treatment.Methods 60 pediatric sinusitis patients were divided into the two groups by the random number table method,gien the control group conventional treatment,and the observational group furoic acid momethasone,pediatric sinusitis nasal spray treatment,then the clinical effect and safety of the two groups of children were observe dand compared.Results After the treatment of the two groups,the observational group total effective rate(96.67%)was significantly higher than that of the control group (70.00%)(χ2 =10.23,P <0.05 ),the incidence of adverse reactions(3.33%)in children with significantly less than the control group(33.33%),which was statistically significant (χ2 =12.48,P <0.05 ).The observational group with bacterial clearance rate was significantly higher than that of the control group(90.91%)in children with bacterial clearance rate(61.90%), which was statistically significant(χ2 =13.26,P<0.05).Conclusion Using mometasone furoate nasal spray in the treatment of sinusitis in children can improve the total efficiency,and with low incidence of adverse reactions,which can effectively improve the clearance rate of bacteria,beneficial to restore the health of children,safe and effective and should be widely used in clinical practice.
3.Simultaneous Determination of Pinoresinol Diglucoside and Chlorogenic Acid in Traditional Decoction and Its Solid Decoction of Sam Soup by HPLC
Yuan LIN ; Liangliang ZHOU ; Yongdong LUO
Chinese Journal of Information on Traditional Chinese Medicine 2013;(10):44-45,46
Objection To estabish a HPLC methold for determining the contents of pinoresinol diglucoside and chlorogenic acid in Sam Soup and its solid decoction. Methods Chromatographic column was Ultimate XB-C18 reversed-phase chromatography column (250 mm×4.6 mm, 5 μm). Mobile phase was acetonitrile-0.4% glacial acetic acid with gradient elutim. The flow rate was 1.0 mL/min, detection wavelength was 277 nm, and column temperature was 40 ℃. Results The pinoresinol diglucoside and showed good linear relationship in the range of 5.0-50.0 μg, r =0.999 9 (n =6), and chlorogenic acid showed linear relationship in the range of 5.4-54.0 μg, r=0.999 6 (n=6). The average recoveries of pinoresinol diglucoside and chlorogenic acid were 98.75% (RSD=1.39%) and 101.11% (RSD=2.69%), respectively. Conclusion The established method was accurate and reliable. The contents of pinoresinol diglucoside and chlorogenic acid in solid decoction are higher than traditional decoction of Sam Soup.
4.Clinical research on chronic lumbosacral osteo-fascial compartment syndrome treated with limited-acupotomy therapy
Rongguo WANG ; Xinxiao LIN ; Jingfei RAO ; Yongdong ZHANG ; Changqin GUO
International Journal of Traditional Chinese Medicine 2011;33(6):484-486
Objective To study the curative effect of limited-acupotomy therapy on chronic lumbosacral osteo-fascial compartment syndrome. Methods 59 patients were randomly recruited into a control group (with 29 patients) and a treatment group (with 30 patients). The control group was treated with general-acupotomy therapy, and treatment group was treated with limited-acupotomy therapy. Evaluate the curative effects before the first and the second therapy, and 3 months after the therapy respectively, as well as VAS pain, JOA and CODI scores. Results The curative effect was 96.56% and 100% respectively in the control group and the treatment group 3 months after the treatment. The difference between the two groups was not statistically significant(χ2=0.19,P> 0.05). As to VAS pain scores, JOA and CODI scores, the difference among the three stages of the treatment were significant (in control group F=165.70, 99.90, 106.60 respectively, in treatment group F=279.76, 154.34, 67.36 respectively, P<0.01)in both groups respectively, but the difference between the two groups were not significant(P>0.05) in each stage. Conclusion Limited-acupotomy therapy was safe and effective in treating chronic lumbosacral osteo-fascial compartment syndrome.
5.Evaluation of effect of fast rehabilitation nursing pathway in patients after artificial hip replacement
Liuxian MO ; Yongdong LIN ; Xuequn ZENG ; Lijuan PAN ; Qingdong PAN ; Weitao HUANG
Chinese Journal of Practical Nursing 2012;28(21):8-10
[Objective] To evaluate the effect of fast rehabilitation nursing pathway in patients after artificial hip replacement.[Methods] 86 patients underwent artificial hip replacement were randomly divided into the control group and the experimental group with 43 cases in each group.The control group received routine care,while the experimental group was given fast rehabilitation nursing pathway.Anxiety and pain at 48h after operation were evaluated,and hip joint function(Harris score)was evaluated six months after operation.[Results] Compared with the control group,anxiety and pain score at 48h after operation decreased markedly,and Harris score six months after operation increased significantly.[Conclusions] Fast rehabilitation nursing pathway can reduce both the short-term and long-term efficacy of patients after artificial hip replacement.
6.Meta-analysis on interspinous dynamic stabilization system Wallis versus Coflex for lumbar degenerative disease
He ZHAO ; Xing YU ; Xiangsheng TANG ; Feng HE ; Yongdong YANG ; Yang XIONG ; Zhenguo HU ; Lin XU
Chinese Journal of Tissue Engineering Research 2017;21(11):1798-1804
BACKGROUND: It is still controversial that interspinous dynamic stabilization system Wallis and Coflex which one can provide better clinical effects for lumbar degenerative disease.OBJECTIVE: To systematically assess the clinical effectiveness and safety of Wallis and Coflex for lumbar degenerative disease.METHODS: According to the computer-based online search of PubMed, Embase, Medline, Cochrane Library, CBM,CNKI, Wanfang Database, and VIP, articles published before August 1st, 2016 were searched. Articles about Wallis comparing with Coflex for lumbar degenerative disease were included; the quality score of methodology was assessed by MINORS. Research data abstracted and synthesized by Review Manager 5.3 were used for meta-analysis.RESULTS AND CONCLUSION: (1) Six studies were included, and all studies were designed for non-randomized controlled trial. (2) There were no significant statistical differences in Japanese Orthopedic Association, Oswestry disability index, visual analogue scale score, Prolo functional score, segmental lordosis angle, and segment movement degree. Incidence of adverse events was significantlue scale less in the Wallis group than in the Conflex group (P < 0.05).(3) There was no significant difference in clinical efficacy between Wallis and Coflex in the early and mid-term follow-up.We can conclude that Wallis may provide better clinical safety than Coflex.
8.Comparison among the mental profile of earthquake student, teacher and the masses survivors
Yongdong HU ; Weidong WANG ; Yanjiao LIU ; Rongjuan GUO ; Caifeng WANG ; Lan HONG ; Yingna LIN ; Fang WANG ; Menghan LU ; Xueyu LU
International Journal of Traditional Chinese Medicine 2010;32(2):166-168
Objective To investigate the prevalence and severity degree of post traumatic stress disorder(PTSD), anxiety and depression, and to explore the different mental profile in different groups involved with an earthquake. Methods 26 days after 8.0 grade earthquake in Wenchuan, psychological rescue team of State Administration of Traditional Chinese Medicine went to some communities in Deyang and Mianzhu area of Sichuan province. In this period, a total of 119 survivors, including students(42), teacher(40) and masses(37), were investigated through impact of event scale (IES), self-rating anxiety scale (SAS) and self-rating depression scale(SDS). Results①The detection rate of score over 19 in IES in 3 groups (students, teacher and masses) were 69%, 80% and 91.9%, respectively. There was significant difference among these 3 groups (F=5.611, P=0.005<0.01) in respect of severity degree of PTSD. ②The values of severity degree of anxiety in 3 groups were significant higher than normal value (P<0.001, all). There was also significant difference among these 3 groups (F=3.376, P=0.038<0.05) in respect of severity degree of anxiety, with the masses group being significant higher than student and teacher group (P=0.029, P=0.022, respectively). ③The values of severity degree of depression in these 3 groups were significant higher than normal value (P<0.05, all). But there was no significant difference (F= 0.670, P=0.514) among these 3 groups. ConclusionThe results suggested the importance to assess PTSD, anxiety and depression in post-disaster area, especially PTSD and anxiety evaluations in the masses group.
9.Comparison of clinical features between respiratory syncytial virus and human rhinovirus lower respiratory tract infection in infants between 2013-2015 in Suzhou
Jiawei CHEN ; Wenjing GU ; Xinxing ZHANG ; Lin DING ; Yinying REN ; Heting DONG ; Zhengrong CHEN ; Yongdong YAN ; Wei JI
Chinese Journal of Applied Clinical Pediatrics 2017;32(16):1239-1243
Objective To analyze the clinical features of infants infected by respiratory syncytial virus (RSV) or human rhinovirus (HRV) in lower respiratory tract in Suzhou area based on the month age and the month of the year.Methods From January 2013 to December 2015,2 206 nasopharyngeal aspirates specimens were collected from the infants with lower respiratory tract infection.Direct immunofluorescence assay was performed to test RSV.Reverse transcription-polymerase chain reaction(RT-PCR) method was used to test HRV.The medical history was collected and pulmonary function tests were performed in some infants who were infected with RSV and HRV.Results In 2 206 cases,total RSV positive rate was 19.90% (439/2 206 cases) and simple RSV infection positive was detected in 399 cases.Total HRV positive rate was 14.14% (312/2 206 cases),in which simple HRV infection positive was detected in 250 cases and the detection rate of RSV was significantly higher than that of HRV(x2 =25.88,P <0.05).The incidence rate of wheezing in simple RSV infection was 68.17% (272/399 cases),which was significantly higher than that of simple HRV infection (42.80%,107/250 cases) (x2 =11.174,P < 0.05).RSV infection was frequent from November to February of the next year in which the detection rate in December was highest with the proportion of 50.00% (99/198 cases) while the rate in June was only 0.57% (1/175 cases).The detection rate of HRV was 22.86% (40/175 cases),20.47% (35/171 cases) and 20.33% (25/123 cases) in June,July and September respectively.The detection rate of HRV was lower during December to February of the next year.In January,the detection rate was only 4.68% (11/235 cases),which was the lowest in the whole year.The detection rates of RSV were 33.33% (4/12 cases),25.21% (118/468 cases),23.46% (84/358 cases) and 23.81% (60/252 cases) in the age group of 28 d-1 month,> 1-2 month,> 2-3 month and > 3-4 months respectively.Up to the age of 4 months old,the detection rate decreased gradually,and with the increase of age and the detection rate in > 7-8 month group was only 10.96% (16/146 cases).The detection rate of HRV was 0 (0/12)and 9.40% (44/468 cases) in the age group of 28 d1 month,> 1-2 month,respectively.After 2 months age old,the detection rate fluctuation ranged from 13.22% to 16.67%.The incidence rate of severe RSV infection was 12.30% (54/439 cases) and the incidence rate of severe HRV infection was 5.13% (16/312 cases).Increased respiratory rate was more common in patients with severe RSV infection while severe HRV infection in infants were accompanied by multiple lobar involvement.After RSV infection,the incidence rate of pulmonary function damage was 89.03% (276/310 cases).After HRV infection,89.27% (183/205 cases)of the infants suffered from pulmonary function damage.Both RSV and HRV infection might cause pulmonary function damage.Conclusions RSV and HRV are the major pathogens in infants of Suzhou areas.The incidence of RSV-induced wheezing is significantly higher than that of HRV.RSV is detected positive mainly in winter and early spring and the infants within 4-month old are susceptible population.HRV is detected positive mainly in June,July and September and the infants older than 2 months are susceptible population.The incidence of severe RSV infection is significantly higher than that of HRV.Severe RSV infection may cause increased respiratory rate and severe HRV infection mainly cause multiple lobar involvement.RSV and HRV infection may cause pulmonary function damage.
10.Establishment of a new rat model of complete spinal cord transection and defect
Feng HE ; Xing YU ; Xiaohong MU ; He ZHAO ; Shaogang LI ; Yongdong YANG ; Pengan LI ; Xiaohong YUAN ; Lingqun ZHU ; Lingling FU ; Lin XU
Chinese Journal of Tissue Engineering Research 2016;20(5):635-639
BACKGROUND:Rat models of complete spinal cord transection are common models for neural tissue engineering. After transecting the spinal cord by the previous methods, gap length of broken end cannot keep relatively uniform, so we cannot objectively evaluate effects of various treatments or tissue engineering materials. OBJECTIVE:The spinal cord transection models were established by using double edged micro scissors, andthe feasibility of this new model was explored by comparing with the conventional method. METHODS: A total of 42 adult female Sprague-Dawley rats were divided randomly into group A (n=6), group B (n=18) and group C (n=18). Group A only received laminectomy. In the group B, the spinal cord was transected with a sharp-pointed knife. Knife point should touch anterior wal of spinal canal and sidewal bone surface. Complete spinal cord transection models were prepared by repeated cutting. In group C, complete spinal cord transection models were established by using self-made double edged micro scissors. RESULTS AND CONCLUSION: (1) At 1 week after model establishment, in the groups B and C, complete paralysis of the hind limbs was found, and BBB scores were similar. However, significant differences in the spacing of broken end were detected. (2) At 4 weeks after model establishment, hind limb functions could restore to different degrees in both groups, but no significant difference in BBB scores was found. (3) At 8 weeks after model establishment, significant differences in hindlimb motor function scores were detectable between both groups. Biotin glucosamine tracer display: In group B, a few labeled axon fibers were observed at the caudal side of the injured spinal cord. In group C, spinal cord was completely transected, and labeled axon fibers cannot be found at the caudal side. (4) Results suggested that the modeling method of self-made double edged micro scissors could effectively eliminate individual differences, contribute to quantitative analysis and comparative study of therapeutic effects.