2.Identification of Ternate Pinellia (Pinellia ternata),Yunnan Jackinthepulpit (Arisaema yunnanense) and Whipformed Typhonium (Typhonium flagelliforme) by UV-Spectrometry
Zhengrong ZHAO ; Yongcheng ZHAO
Chinese Traditional and Herbal Drugs 1994;0(12):-
Alcoholic (70%) extract of Pinellia ternate, Arisaeme yunnanense and Typhonium flagelliforme were analysed by UY-spectrometry. Results showed that each of them had its own characteristics spectrum and was repcatable. This provides a method for the identification of three kinds of drug.It was discovered that the wavelength of maximum absorbance showed aggreement,when P.ternata from different origin were analysed by UV-spectrometry.
3.Study on Quality Standards for Brain's King Oral Solution
Chinese Traditional Patent Medicine 1992;0(05):-
Objective: To establish the quality control standards for Brains' King Oral solution. Methods: Rhizoma Gastrodia, Rhizoma et Radix Noto-pterygii in oral solution were identified by TLC. The content of gastrodin in Brain's King Oral Solution was determined by HPLC with external standard. The average recovery was 99.22% and RSD was 0.99%(n=6).Results: These methods are simple, accurate and specific.Conclusion: These methods can be used for the quality control of Brain's King Oral Solution.
4.Vinorelbine plus oxaliplatin in the treatment of advanced non-small-cell lung cancer
Yongcheng LI ; Yunjuan ZHAO ; Haiyan WU
China Oncology 1998;0(04):-
0.05). The main toxicities were well tolerated and consisted of leukopenia,nausea/vomiting and peripheral neuritis. Grades Ⅲ-Ⅳ nausea/vomiting,renal toxicity and cardiac insufficiency occurred more frequently in the control group,peripheral neuritis occurred more frequently in the study group (P
5.Transfer of ERR for radiation-related leukemia from Japanese population to Chinese population
Liqiong HUANG ; Zhijuan SUN ; Yongcheng ZHAO ; Jixian WANG
Chinese Journal of Radiological Medicine and Protection 2011;31(4):474-477
Objective To establish a transfer model for excess relative risk (ERR) for radiation-related leukemia from Japanese population to Chinese population.Methods Combined ERR of several subtypes of leukemia published in 1994, with the corresponding leukemia baseline incidence rates obtained from Cancer Incidence in Five Continents Vol.Ⅸ (CI5-Ⅸ) for Japanese population and Chinese population, a weighted risk transfer model was employed between an additive model and a multiplicative model, to execute ERR transfer.Results A range of weighing factors was proposed for risk transfer models:weighing factor was 0.4 for male and 0.3 for female, acute lymphoblastic leukemia, acute myeloid leukemia and chronic myeloid leukemia.The uncertainty for ERR transfer was characterized by lognormal distribution.Conclusions Based on the difference of baseline incidence rate for subtypes of leukemia between Japanese population and Chinese population, the transfer model and these weighing factors discussed in the present study could be applicable to transfer ERR for radiation-related leukemia from Japanese population to Chinese population.
6.Comparative analysis of postoperative atrial fibrillation in esophagus cancer and lung cancer patients
Xianrong SHANG ; Jianjun WANG ; Yongcheng PAN ; Feng ZHAO ; Lifeng MENG
Chinese Journal of Postgraduates of Medicine 2006;0(35):-
Objective To investigate the incidence, causes, management and prognosis of atrial fibrillation (AF) after operation of esophagus cancer(EC)and lung cancer(LC). Methods The patients of postoperative AF following EC and LC surgery between December 2004 and May 2006 were taken into EC group and LC group. Results AF occurred in 27 patients ( 11.2%) of EC and in 18 patients (5.6%) of LC. The duration of operating and the level of urine catecholamine within the first two days after operation in the EC group were higher than those of the LC group (P0.05). All patients had been cured. Conclusions The EC predominate over the LC in the incidence of AF after operation; the early medicine treatment needs to be advisable to patients, and the patients of LC can be treated with removing causes at first.
7.The clinic application of microwave heliotherapy in the malignant bone tumors of pelvis
Jingtao JI ; Yongcheng HU ; Hongchao HUANG ; Qun XIA ; Shangkun ZHAO
Chinese Journal of Orthopaedics 2011;31(6):629-634
Objective To investigate the clinical outcomes of microwave heliotherapy in situ on the primary or metastatic malignant tumors of the pelvis.Methods From February 2000 to April 2009,18 patients with primary or metastatic malignant tumors of the pelvis were treated with microwave heliotherapy in situ,and followed a total or partial tumor resection.There were 11 males and 7 females with an average age of 45 years(range,16-72).Twelve cases were diagnosed as primary malignant tumor and 6 as metastases.Locations of tumors involved:the Ⅰ region 6 cases.the Ⅱ region 10 cases.and the Ⅲ region 2 cases.The exposures of all tumors were via aTtype or ilioinguinal approach.The lesions were heated at 50℃ for 20 min by 2450 MHz microwave,with surrounding soft tissue protected by copper.mesh.The necrotic tumor tissues were total or partial excised after treatment,with preservation of the anatomical continuity of the pelvic ring.Results The duration of surgery was 60-180 min (110 min on average).The blood loss was 400-800ml(480 ml on average).All patients were followed-up for 0.5-7 years(3.5 years on average).Tumor local recurred in 1 case with chondrosarcoma,and was survival in tumor-bearing after 6 months follow up.One case with malignant fibrous histiocytoma died due to brain,pulmonary,and all body metastases.One case with osteosarcoma died due to pulmonary metastases.Five cases with the metastases died due to non-pelvis metastases.Functions of hip joint in 18 patients were as follows:flexion 80°-130°,extension 0°-10°,abduction 25°-35°,and adduction 18°-23°.Conclusion The clinical result demonstrated that the advantages of microwave heliotherapy in situ were quick increase of temperature,sensitive responses,easy control of temperature,and effective inactivation of tumor cells in the malignant bone tumors of pelvis.
8.Clinical value of hand-sewn ileal pouch anal anastomosis after proctocolectomy for the treatment of ulcerative colitis
Yongcheng LYU ; Hao WANG ; Ke ZHAO ; Hongqiu HAN
Chinese Journal of Digestive Surgery 2014;13(8):612-616
Objective To investigate the clinical value of hand-sewn ileal pouch anal anastomosis (HIPAA) for the treatment of ulcerative colitis.Methods The clinical data of 191 patients with ulcerative colitis who were admitted to the General Hospital of Tianjin Medical University from January 1989 to December 2013 were retrospectively analyzed.All the patients received proctocolectomy and open or laparoscopic HIPAA.Patients were followed up by questionnaire at postoperative month 3 and 12.The function of pouch was evaluated according to the defecation frequency per 24 hours and per night,Bristol scale stool form and Kirwan classification.The quality of life was assessed according to the Cleveland global quality of life (CGQL).Patients were followed up till April 2014.The independent samples were compared by t test,and data from multiple groups were compared by analysis of variance,pairwise comparison was done by LSD-t test,and the count data were analyzed using the chi-square test.Results Of the 191 patients,180 received open surgery and 11 received laparoscopic surgery.Nine patients were treated by one-stage surgery,175 by two-stage surgery and 7 by three-stage surgery.The pouches of 181 patients were J shape,9 were H shape and 1 was W shape.No patient died perioperatively.Eight patients had abdominal infection and 7 had incisional infection at early period after the operation,and they were cured by antibiotics.Four patients had pouch anastomotic bleeding and 4 had anastomotic leakage at postoperative week 1-2,and they were cured by local hemostasis or titanium clipping.Six patients had high intestinal obstruction,and they were alleviated by symptomatic treatment.Eight patients had inflammation of pouch,and they were alleviated by diet adjustment or antibiotics treatment.Two patients had sexual dysfunction.All the patients were followed up for 1-25 years.The function of the pouch was improved gradually.At postoperative month 12,the defecation frequencies were (3.7 ± 1.4)/24 hours and (1.3 ±0.5)/night,and the number of patients with type Ⅳ (Bristol classification),type Ⅴ,type Ⅵ and in grade Ⅰ (Kirwan classification),grade Ⅱ,grade Ⅲ were 107,76,8 and 177,8,6,respectively,which were significantly improved when compared with (6.5 ±2.8)/24 hours,(2.9 ± 1.5)/night,86,89,16 and 160,19,12 at postoperative month 3 (t =12.36,3.98,x2=7.76,29.27,P< 0.05).The CGQL indexes before operation and at postoperative month 3 and 12 were 0.37 ±0.19,0.67 ±0.16 and 0.82 ±0.13,respectively,with significant differences (F =6.011,P <0.05).There were significant differences between the CGQL indexes before operation and at postoperative 12 and 3 months (t =16.69,10.06,P < 0.05).A significant difference was also observed between the CGQL indexes before operation and at postoperative 12 months (t =27.01,P < 0.05).Conclusions HIPAA is suitable for the surgical treatment of ulcerative colitis.The function of the pouch is good and the quality of life is improved.
9.Estimation of radiogenic cancer risk coefficients of stomach cancer in Chinese population
Zhijuan SUN ; Jixian WANG ; Jian XIANG ; Yongcheng ZHAO ; Jingyun CHEN ; Qingqing YANG ; Saijun FAN
Chinese Journal of Radiological Medicine and Protection 2015;35(4):282-286
Objective To estimate the excess relative risk coefficients of stomach cancer for Chinese population attributable to ionizing radiation.Methods The excess relative risk and excess absolute risk coefficients of stomach cancer were estimated based on Life Span Study by using risk models developed by BEIR Ⅶ committee (Biological Effect of Ionizing Radiation).Guided by transportation methods from Life Span Study to Americans,we determined that transportation method for Chinese population includes both multiplicative and additive models with a weight of 0.7 and 0.3 respectively,on an arithmetic scale.Besides,curve fitting was used to obtain sex-age-specific stomach cancer baseline incidence based on Chinese cancer annual report.Then,Chinese excess relative risk coefficients of stomach cancer were obtained by substituting excess relative risk,excess absolute risk of Life Span Study and Chinese baseline incidence rate into risk transportation model.Results Excess relative risk coefficients of stomach cancer for Chinese population are 0.26/Sv for male and 0.64/Sv for female,whose exposure age is 30 years old and cancer age is 60 years old.Coefficients increase with decreased exposure age and cancer age.Conclusions Excess relative risk coefficients of stomach cancer for Chinese population are by larger higher than that of Life Span Study,and their sex-age tendency are similar.
10.Transfer of radiation related leukemia risk from Japanese population to Chinese population
Jingyun CHEN ; Zhijuan SUN ; Guanhua REN ; Qingqing YANG ; Jixian WANG ; Saijun FAN ; Yongcheng ZHAO
Chinese Journal of Radiological Medicine and Protection 2015;35(2):134-138
Objective To estimate the averaged excess relative risk(ERR) in Chinese population based on the radiogenic cancer risk of leukemia in Japanese atomic bomb survivor cohort,and to discuss proper method suitable for risk transfer between populations.Methods Based on BEIR Ⅶ radiogenic cancer model and population transfer model,and the 2009 Chinese leukemia baseline rates given in 2012 Chinese Cancer Registry Annual Report,comparison was made of population incidences in seveal countries to adjust the weighting factors.Results The ERR of three subtypes of leukemia as a whole was obtained,and the weighting factors for risk transfer model was assumed.The additive factor for male was 0.2,and the multiplicative factor was 0.8,while the additive factor for female was 0.15,and the multiplicative factor was 0.85.Conclusions For the risk transfer between populations,weighting factor was adjusted as a whole to obtain the ERR value for estimating the risk to Chinese population.The risk transfer method suitable for Chinese population was obtained by using the incidence rate available for Chinese population to directly transfer radiation-induced leukemia risk to Chinese from Japanese.