8.Distribution and clinical significance of human papillomavirus subtypes in Shenzhen People's Hospital
Min TANG ; Yong DAI ; Xiaoping LU ; Tiyuan LI
Journal of Third Military Medical University 2003;0(21):-
Objective To investigate the distribution of human papillomavirus(HPV) subtypes in condyloma acuminatum(CA) patients in Shenzhen People's Hospital and assess the association between HPV subtypes and cervix neoplasm.Methods Type specific prevalence and extent of multiple infection were assessed in the genital tract CA samples collected from 352 patients visiting Departments of dermatology or gynecology of Shenzhen People's Hospital during 2003-2004.PCR using MY09/11 as primer and reverse dot blot hybridization for the genotyping of 9-20 HPV subtypes.Results HPV type diversity was broad in the investigated CA patients.The low risk HPV type(HPV subtype 11,6) was dominant and multiple HPV infections occurred in 37% of HPV-positive samples.High risk HPV type was dominant in CA from cervix,especially in the high grade cervical intraepithelial neoplasia(CIN Ⅱ+),and multiple high risk HPV(HR-HPV) infection was found in 87% of HPV positive samples.Conclusion HPV subtypes 6 and 11 were dominant in the patients visiting Shenzhen People's Hospital.HPV subtypes 16 and 18 may be the main causes of malignant changes of cervix.
9.Evaluation study of influence factors for the quality of life of nurses group in Shenzhen city
No TANG ; Yong XIONG ; Shiqi XIAO ; Min ZHOU ; Wenzhi CAI
Chinese Journal of Practical Nursing 2011;27(19):1-4
Objective To investigate the quality of life of nurses group in Shenzhen city and explore its influencing factors, so as to provide evidence for health policy making health promotion and science research. Methods Self-designed questionnaires were used in social demography survey and SF-36 was adopted to survey 495 in-service nurses on front line from four hospitals in Shenzhen. Paired samples t Test and multivariable stepwise regression were carried out to analyze the quality of life among nurses in Shenzhen city and general population in China. Results The data showed the scores of the physiological domain, psychological domain and quality of life nurses in Shenzhen city and Chinese general population was (68.60±17.61), (69.91±17.91), (67.29±20.29)and (78.18± 15.88), (79.36±17.00), (77.00± 17.42), respectively. The difference had statistical significance. Multivariable stepwise regression showed that quality of life was positively correlated with APN scheduling, education, department, monthly income, working range, age and the hospital level in descending sort Conclusions Health authorities, hospital leaders and nurses-selves should pay more attention to the quality of life for nurses group and take positive mea-sures to improve quality of life of nurses group.
10.Advances in minimal residual disease detection with flow cytometry in childhood acute myeloid leukemia.
Jian-hua FENG ; Xiao-jun XU ; Yong-min TANG
Chinese Journal of Pediatrics 2013;51(3):231-234
Adolescent
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Child
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Child, Preschool
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Clinical Trials as Topic
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Flow Cytometry
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Hematopoietic Stem Cell Transplantation
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Humans
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Immunophenotyping
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Leukemia, Myeloid, Acute
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diagnosis
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pathology
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therapy
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Neoplasm, Residual
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diagnosis
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pathology
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therapy
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Polymerase Chain Reaction
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Prognosis
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Recurrence
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Sensitivity and Specificity