1.Trends of psychiatric consultation at the St. Mary's Hospital.
Yong Sil KWEON ; Jin Hee HAN ; Tae Yul LEW
Journal of Korean Neuropsychiatric Association 1991;30(4):729-738
No abstract available.
2.Classification of Adolescent Suicide Based on Student Suicide Reports
Hoin KWON ; Hyun Ju HONG ; Yong-Sil KWEON
Journal of the Korean Academy of Child and Adolescent Psychiatry 2020;31(4):169-176
Exploring the risk factors of adolescent suicide is important for effective suicide prevention. This study explored the clustering of adolescent suicides based on six risk factors: mental disorder, broken family, depression, anxiety, previous suicide attempts, and deviant behaviors. Using 173 student suicide reports obtained from the Ministry of Education, we evaluated the associations between suicide and variables related to mental disorders; dysfunctional family life; depression and anxiety; previous suicide attempts; deviant behaviors such as drinking and smoking; and school life characteristics, including attendance and discipline, problems within the past year, and incidents prior to suicide. In addition, reports of warning signs just before suicide were included in the analysis. The two-stage cluster analysis classified the students into three clusters: the silent type (cluster 1; 48.55%), in which no risk factors were observed; environmental-risk type (cluster 2: 24.28%), which featured a high frequency of broken households, deviant behaviors such as smoking/drinking and running away from home; and depressive type (cluster 3: 27.17%), which featured a high frequency of mental health problems such as depression, anxiety, and suicide attempts. Identifying the sub-types of adolescent suicide may help to inform tailored suicide prevention and intervention strategies in school.
5.Characteristics of Violent Behavior in Psychiatric Inpatients.
Tae Youn JUN ; Yong Sil KWEON ; Kyu Young TOH
Journal of Korean Neuropsychiatric Association 1997;36(3):512-522
To evaluate the characteristics of violent behavior of psychiatric inpatients, the authors reviewed clinical records of psychiatric patients who had admitted at UiJong Bu St. Mary's Hospital from January 1994 to lune 1995. We divided the 287 subjects into violent and nonviolent group according to the presence of violent behaviors in psychiatric ward. We assessed demographic variables, clinical characteristics and violent behaviors using Overt Aggression Scale and compared these variables of violent group with nonviolent group. The results were as follows: 1) The number of violent patients was 72(25.1% of the total). 2) In terms of demographic variables, the differences between two groups in education and occupation were significant(p<.05). 3) In psychiatric diagnoses, violent group were more likely to have mania, schizophrenia and organic rental disorder in sequence but there were no differences between violent and nonviolent group. 4) The history of violent behavior was greater in violent group(p<.001) and the mode of admission was significantly different between two groups(p<.005). 5) In cluster of psychopathology on admission, more frequently found clusters of psychopathology in violent group were agitation-excitement and hostile- suspiciousness and there were significant differences between two groups(p<.001). 6) The length of stay in violent group(59.3 days)was significantly longer than nonviolent group(38.4 days)(p<.001). 7) The types of violent behavior were verbal aggression, physical aggression against objects and physical aggression against other people in frequency sequence. 8) The most frequent type of behavioral clue before violent behavior was hyperactive, loud, verbally abusive, angry, hostile(68.1%). 9) Most of violent behaviors were presented between midday and 6 pm. in resting time. 10) 62.3% of total violent behaviors were occurred within first week following admission. 11) The variables which showed significant effects on total aggression score were religion, educational status, occupation, mode of admission, psychiatric diagnosis, psychopathology on admission and history of violent behavior before admission. In summary, these results showed similar trends compared to previous studies on characteristics of psychiatric inpatients. And we fecund that more important predictors of violent behavior in practice were likely to be history of violent behavior, psychopathology on admission and behavioral cue before violent behavior.
Aggression
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Bipolar Disorder
;
Cues
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Diagnosis
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Education
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Educational Status
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Humans
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Inpatients*
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Length of Stay
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Mental Disorders
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Occupations
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Psychopathology
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Schizophrenia
6.VNTR Polymorphism of the Tyrosine Hydroxylase in Bipolar Patients.
Yong Sil KWEON ; Kyu Young TOH ; Tae Youn JUN ; In Ho PAIK
Journal of Korean Neuropsychiatric Association 1998;37(2):363-371
OBJECTIVES: Tyrosine hydroxylase(TH) is a rate-limiting enzyme in the synthesis of catecholamines, and could be a candidate gene for causing the bipolar disorders. Therefore, we designed this study to investigate the association of the VNTR(variable number of tandem repeats) polymorphic locus in the first intron of the TH gene with bipolar disorders. METHODS: We typed VNTB polymorphic region of the TH gene using PCR in 115 bipolar patients and 85 normal controls. Four types of alleles(A, B, C, D) were typed according to the difference of the repeat(TCAT)6-9 number. The frequencies of allele and genotype were compared between patients and normal controls, and in patients and normal controls allelic frequencies were compared respectively in terms of family history of affective disorders and age of onset. RESULTS: 1) The allelic frequencies were significantly lower in type A, and significantly higher in type D in patient group compared to control group. The genotype frequencies were significantly higher in type BD in patient group than in control group. 2) In comparing the allelic frequencies among patient group with and without family history and control group, there were no significant differences between groups with and without family history, whereas patient group with family history showed lower significance in type A and higher significance in type D compared to control group. 3) In comparing the allelic frequencies among patient groups with early onset and late onset and control group, patient group with early onset showed higher significance in type D than patient group with late onset and showed lower significance in type A and higher significance in type D compared to control group. CONCLUSIONS: The authors conclude that the VNTR polymorphic region of the TH gene might be associated bipolar disorders, and type A and type D alleles might be susceptibility genes of bipolar disorder.
Age of Onset
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Alleles
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Bipolar Disorder
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Catecholamines
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Genotype
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Humans
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Introns
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Mood Disorders
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Polymerase Chain Reaction
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Tyrosine 3-Monooxygenase*
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Tyrosine*
7.Decreased Recognition of Facial Affects in Elderly.
Kyoung Uk LEE ; Jeong Ho CHAE ; In Chul CHOI ; Hae Kook LEE ; Yong Sil KWEON ; Chung Tae LEE
Journal of Korean Neuropsychiatric Association 2005;44(2):259-263
OBJECTIVES: The purpose of this study was to investigate whether elderly and young adults differ in their recognition of facial expressions of emotion. METHODS: A total of 120 (elderly group 53, young group 67) subjects participated in this study. Korean facial expressions of emotion including happiness, sadness, fear, anger, disgust, surprise and neutral were used as stimuli for facial affect recognition test. Computerized facial affect recognition test that consists of facial affect discrimination test and facial affect intensity test was performed. RESULTS: For facial affect discrimination test, there was a significant difference between two groups (F=3.986, p<.01) after controlling the effect of education. Elderly participants showed significantly less correct recognition rate with sadness, anger and disgust (p<.05). For facial affect intensity test, there was no significant difference between the groups in recognition of emotional intensity. Chi-square test or t-test was done according to the clinical variables. Multivariate analysis of covariance was done to test group differences of correct recognition rate and emotional intensity. CONCLUSION: This is the first report of differential decrease of facial affect recognition in elderly using Korean facial expressions. This study suggests that the decrement of facial affect recognition maye be a part of normal aging process.
Aged*
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Aging
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Anger
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Discrimination (Psychology)
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Education
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Facial Expression
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Happiness
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Humans
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Multivariate Analysis
;
Young Adult
8.Deficits in Facial Emotion Recognition in Schizophrenia: A Replication Study with Korean Subjects.
Seung Jae LEE ; Hae Kook LEE ; Yong Sil KWEON ; Chung Tai LEE ; Kyoung Uk LEE
Psychiatry Investigation 2010;7(4):291-297
OBJECTIVE: We investigated the deficit in the recognition of facial emotions in a sample of medicated, stable Korean patients with schizophrenia using Korean facial emotion pictures and examined whether the possible impairments would corroborate previous findings. METHODS: Fifty-five patients with schizophrenia and 62 healthy control subjects completed the Facial Affect Identification Test with a new set of 44 colored photographs of Korean faces including the six universal emotions as well as neutral faces. RESULTS: Korean patients with schizophrenia showed impairments in the recognition of sad, fearful, and angry faces [F(1,114)=6.26, p=0.014; F(1,114)=6.18, p=0.014; F(1,114)=9.28, p=0.003, respectively], but their accuracy was no different from that of controls in the recognition of happy emotions. Higher total and three subscale scores of the Positive and Negative Syndrome Scale (PANSS) correlated with worse performance on both angry and neutral faces. Correct responses on happy stimuli were negatively correlated with negative symptom scores of the PANSS. Patients with schizophrenia also exhibited different patterns of misidentification relative to normal controls. CONCLUSION: These findings were consistent with previous studies carried out with different ethnic groups, suggesting cross-cultural similarities in facial recognition impairment in schizophrenia.
Collodion
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Ethnic Groups
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Humans
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Schizophrenia
9.Overactive Bladder Successfully Treated with Duloxetine in a Female Adolescent.
Sheng Min WANG ; Hae Kook LEE ; Yong Sil KWEON ; Chung Tai LEE ; Kyoung Uk LEE
Clinical Psychopharmacology and Neuroscience 2015;13(2):212-214
Overactive bladder (OAB) is defined as urgency, usually with frequency and nocturia, and with or without urge incontinence. Duloxetine, an antidepressant that inhibits reuptake of serotonin and norepinephrine, is indicated for the treatment of stress urinary incontinence in Europe. In this paper, we present a case of a 17-year-old female patient with OAB and depressive symptoms who was successfully treated with duloxetine. This case suggests duloxetine can be an option for patient with OAB, and it also highlights the need for further studies of duloxetine's use in the treatment of OAB.
Adolescent*
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Depression
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Europe
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Female*
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Humans
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Nocturia
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Norepinephrine
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Serotonin
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Urinary Bladder, Overactive*
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Urinary Incontinence
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Urinary Incontinence, Urge
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Duloxetine Hydrochloride
10.A Methodological Review of Psychological Autopsy for Adolescents.
Hoin KWON ; Ran KIM ; Soo Young BHANG ; Hyun Ju HONG ; Yong Sil KWEON
Journal of the Korean Academy of Child and Adolescent Psychiatry 2014;25(3):121-127
Recently, local governments and suicide prevention centers have been trying to implement psychological autopsy. This effort has focused on adult suicide so far ; however, there are some difficulties in its application to adolescent suicide. Therefore, in this study, psychological autopsy studies of Korea were reviewed, and a methodology for adolescents\' psychological autopsy was suggested. For the effective performance of the psychological autopsy in adolescent suicide, cooperation with each area of the government and implementation of bodies is necessary. In addition, the central system, which disseminates the standardized interview to the community and manages the data nationwide, should be prepared. Also, in order to improve the accuracy of diagnosis and to obtain various types of information, a structured interview should be adopted as the psychological autopsy, as well as considering the use of social media. Investigation of specific risk factors for adolescent suicide through psychological autopsy can enable determination of the intervention point for effective suicide prevention.
Adolescent*
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Adult
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Autopsy*
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Diagnosis
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Humans
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Korea
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Risk Factors
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Social Media
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Suicide