2.Analysis of the difference of three imaging methods of the MRA in detection of cerebral infarction
Huihong FU ; Min LI ; Yong HUANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(10):1506-1507
Objective To compare the clinical value of fluid attenuated inversion recovery imaging (FLAIR),magnetic resonance diffusion-weighted imaging(DWI) and magnetic resonance angiography(MRA) in diagnosis of early cerebral infarction.Methods 70 cerebral infarction patients were chosen.They underwent FLAIR,DWI and MRA examination.Results 70 patients with early cerebral infarction mostly were multiple lessions accouting for 60%.Supper actue period had 22 cases and acute period had 48 cases.DWI had the highest detection rate of cerebral infarction,particularly in the hyperacute period the detection rate reached 100%,which was significantly higher than the FLAIR and MRA(x2 =12.4,P < 0.05).Conclusion Especially in the early diagnosis of hyperacute cerebral infarction,DWI is superior to FLAIR and MRA.FLAIR showed better on the cortex and periventricular lesions,MRA can check out the blood vessel lesions in the infarction area.
4.Investigation on occupational disease in Guangxi province from 1992 to 2005.
Yong-Qiang LI ; Xian-Min GE ; Hong LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(12):741-744
Adolescent
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Adult
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Aged
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Aged, 80 and over
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China
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epidemiology
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Female
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Humans
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Male
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Middle Aged
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Occupational Diseases
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epidemiology
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Young Adult
5.Changes and Clinical Significance of Serum GM-CSF, IL-6 and TNF-α Levels in Patients with Rheumatoid Arthritis
Yaqin LI ; Yong YAN ; Min HUANG ; Jing LI ; Wei ZHANG
Progress in Modern Biomedicine 2017;17(24):4702-4705
Objective:To investigate the changes and clinical significances of serum levels of granulocyte macrophage colony-stimulating factor (GM-CSF),interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels in patients with rheumatoid arthritis (RA).Methods:126 cases of patients with RA in our hospital from June 2013 to December 2016 were selected as RA group and divided into two subgroups as active RA group (69 cases) and remission RA group (57 cases) according to the severity of the disease.55 healthy cases who receive physical check in our hospital at same time were selected as the control group.The serum GM-CSF,IL-6 TNF-α levels were detected by enzyme linked immunosorbent assay (ELISA) and compared between different groups,the correlation of serum GM-CSF,IL-6 TNF-α levels with DAS28 were analyzed.Results:The serum GM-CSF,IL-6 TNF-α levels of RA group were significantly higher than those of the remission RA group and control group (P<0.01),and the serum GM-CSF,IL-6 TNF-α levels of remission RA group were also significantly higher than those of the control group (P<0.01).Positive correlation between serum GM-CSF,IL-6 and TNF-α levels were found(P<.0.01).The level of DAS28 was significantly correlated with the levels of serum GM-CSF,IL-6 and TNF-α (r=0.473,0.584,0.675,all P<0.01).Conclusion:The levels of serum GM-CSF,IL-6 and TNF-α were up-regulated in patients with RA and positively correlated with the activity of RA,which might be of important clinical significance in the early diagnosis,disease evaluation and prognosis of RA.
6.Detection and significance of phosphatidylinositol 3-kinase in adipose tissue of polycystic ovary syndrome patients with insulin resistance
Yong-Li CHU ; Hong-Yu QIU ; Yong-Yu SUN ; Min LI ; Hong-Fa LI ;
Chinese Journal of Obstetrics and Gynecology 2001;0(07):-
Objective To investigate the expression of phosphatidylinositol 3-kinase(PI-3K)in adipose tissue of polycystic ovary syndrome patients(PCOS),and explore molecular mechanisms of insulin resistance(IR)in PCOS.Methods Samples from patients with PCOS with IR(n=19),PCOS without IR (n=10)and controls(n=15)were collected.Serum fasting insulin(FIN)and fasting plasma glucose (FPG)were measure& Insulin resistance index was calculated using homeostasis model assessment (HOMA)to analyze the relationship between these markers and IR.Western blot technique was used to detect the PI-3K p85 subunit.Gene expression of PI-3K p85 subunit was detected by reverse transcription polymerase chain reaction(RT-PCR)method.Kinase activity was detected by immunoprecipitation,thin- layer chromatography and gamma scintillation counting.Results(1)The levels of FIN[(25.2?3.8) mU/L]and HOMA-IR(1.6?0.3)in PCOS with IR were significantly higher than those in PCOS without IR[(13.4 +3.8)mU/L,0.9?0.3]and controls[(9.5 +2.6)mU/L,0.5?0.3;all P<0.05).(2) There was no significant difference in the protein(0.65?0.10)and gene expression(0.92?0.12)of PI-3 K p85 subunit in PCOS with IR compared with PCOS without IR(0.72?0.10,1.01?0.10)and control groups(0.73?0.14,1.00?0.12;P>0.05).(3)PI-3K activity in PCOS with IR(81%)and PCOS without IR(89%)was significantly decreased(P<0.01,P<0.05)and negatively correlated with HOMA- IR(r=-0.69,P<0.01;r=-0.62,P<0.05).Conclusions No significant difference in the protein and gene expression of PI-3K p85 subunit in PCOS with IR is found.The decreased PI-3K activity may lead to IR of PCOS.
7.Review of research and development and significant effect of Hippophae rhamnoides.
Yong LIU ; Yong-Shan LIAN ; Ying-Li WANG ; Min-Hui LI ; Pei-Gen XIAO
China Journal of Chinese Materia Medica 2014;39(9):1547-1552
Hippophae rhamnoides is one of the most representative economy crops for its wide uses of biological diversity and abundance of resource. As the key healthy food development and ecology protection, H. rhamnoides has been developed widely. Meanwhile, the development of H. rhamnoides has obtained great achievements. Nowadays, H. rhamnoides is still a necessary economy crop, while it has great influence on ecology protection. This paper discussed the phytochemistry, pharmacology, clinical application and product development, and propounded some suggestions for future research and economy development to get comprehensive benefit of H. rhamnoides and to serve for well-off society.
Biomedical Research
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methods
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trends
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Drugs, Chinese Herbal
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chemistry
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therapeutic use
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Flavonoids
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chemistry
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therapeutic use
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Hippophae
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chemistry
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Humans
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Molecular Structure
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Phytotherapy
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methods
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trends
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Polyphenols
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chemistry
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therapeutic use
8.Continuous intravenous infusion of midazolam for treatment of status epilepticus in children.
Jian-min ZHONG ; Jian-hua LI ; Yong CHEN
Chinese Journal of Pediatrics 2004;42(4):299-300
Adolescent
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Age Factors
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Anti-Anxiety Agents
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administration & dosage
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adverse effects
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therapeutic use
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Infusions, Intravenous
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Male
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Midazolam
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administration & dosage
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adverse effects
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therapeutic use
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Status Epilepticus
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drug therapy
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Treatment Outcome
9.A cross-lagged regression analysis between resilience, mental health and psychological stress of recruits during training
Yi MIAO ; Min LI ; Yong LAN ; Yupei ZHANG ; Bo CHEN
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(1):59-62
ObjectiveTo explore the resilience and mental health of recruits during training,and to investigate mutual prediction of resilience between mental health and psychological stress to provide the scientific evidence for the mental health training and psychological selection of recruits.MethodsConnor-Davidson resilience questionnaire ( CD-RISC),symptom checklist ( SCL-90 ),psychological stress self-evaluation test ( PSET),satisfaction with life scale (SWLS),positive and negative affect scale (PANAS) were applied to 650 recruits in 2011 before starting training and after two months of training.Results ① Chinese recruits had good resilience,and the CD scores of pre-and post-test were (61.60 ± 14.36) and (61.41 ± 14.55 ) respectively.②Mental health (SCL-90) of two tests were good in recruits.③ Correlation analysis showed that the same premise of phase correlation,resilience (pre-test) could significantly predict mental health (post-test) ( β =0.070,P < 0.05 ),mental health ( pretest) could not predict resilience (post-test) (β =0.015,P > 0.05 ).Resilience (pre-test) could significantly predict psychological stress (post-test) ( β =0.075,P < 0.05 ),psychological stress (pre-test) could not predict resilience (post-test) (β =0.017,P > 0.05 ).④ Compared with high resilience group,low-resilience group of recruits had higher total score of SCL-90 and psychological stress and less positive emotion,more negative emotion and lower life satisfaction.ConclusionThe recruits training have good resilience.Resilience of recruits have predictive ability to mental health,psychological stress during training.
10.Studies on Dynamics of Two Endophytic Bacterial Strains Inside Ginseng and Soil of Root Region
Min LIU ; Chenyun HU ; Wanlong DING ; Yong LI
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(4):790-795
This article was aimed to study the dynamics of biocontrol endobacteria in roots, stems and leaves of Panax ginseng and soils adjacent roots. Gradient screening and root irrigation methods were used to develop Rif-resistance bacteria and inoculation. Dilution plate method was used to count the number of them in roots, stems and leaves of P. ginseng and soils adjacent roots. The results showed that bacteria which can endure 120 μg·mL-1 Rif was developed, and no change was found on their antagonistic activity against A lternaria panax Whetz and Phytophthora cactorum. In roots and stems of P. ginseng, ge15 and ge25 showed the highest number in the initial.Then, populations of ge15 and ge25 in ginseng roots and stems decreased to a stable status gradually. In ginseng leaves, populations of ge15 and ge25 increased to the highest 3 days after inoculation, then, populations of them were decreased and kept at certain concentration. In ginseng rhizosphere soil, populations of ge15 showed reciprocating change, and which of ge25 showed increase initial, and then decrease to a stable status. It was concluded that endobacteria can keep a certain population in ginseng roots, stems, and leaves. Biocontrol agents based on them will be helpful for ginseng diseases controlling in the field.