1.SURGICAL TREATMENT OF CONGENITAL SCOLIOSIS WITH DIASTEMATOMYELIA
Jun PENG ; Yong HAI ; Huason MA
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
To study the clinical characteristics and surgical treatment of congenital scoliosis with diastematomyelia, four patients were found to have scoliosis with diastematomyelia by CT and MRI.The first step of surgery was to excise the osteal compartion in spinal cord, the second step was the posterior scoliosis correction and fusion after two weeks. All the patients had successful surgery. The body height of the patients increased 4 75cm and the Cobb angle deceased 43? in average. No complication was found in the nervous system. This method is very effective, and is worth popularizing its application.
2.Family doctor team care reduces morbidity of disabled elderly in home care
Jun ZHAO ; Yong MA ; Lei PENG ; Fuliang ZHANG
Chinese Journal of General Practitioners 2016;15(7):524-528
Objective To assess the effect of family doctor team care on morbidity of disabled elderly in home care.Methods Eighty six disabled elderly patients with home care in Shanghai Xujiahui community were enrolled from February 2014 to January 2015.The patients were randomly divided into intervention group and control group with 43 cases in each.In intervention group,the family doctor team provided long-term,comprehensive and integrated care,and in control group the conventional home care was provided.The rates of morbidity and readmission to hospital were documented during the 3,6 and 12 monthfollow-up,and compared between two groups.Results The incidence rates of bedsore,pneumonia and deep vein thrombosis in intervention group was significantly lower than those in control group [after 6 months:4.9% (2/41) vs.28.9%(11/38),x2 =8.311;2.4% (1/41) vs.21.1% (8/38),x2 =6.769;2.4% (1/41) vs.15.8% (6/38),x2 =4.353,respectively;after 12 months:2.4% (1/41) vs.42.1% (16/38),x2 =18.374;4.9% (2/41)vs.28.9% (11/38),x2 =8.311;7.3% (3/41)vs.28.9% (11/38),x2 =6.328,respectively;all P <0.05].The number of cases with bedsore healing(6/7 vs.0,x2 =18.555)and pneumonia recovery[5/6 vs.4.3% (1/23),x2 =18.092] was significantly more and that with pneumonia deterioration (0 vs.52.2% (12/23),x2 =5.340)was significantly less in intervention group than those in control group (all P < 0.05).More cases with deep vein thrombosis improved(1/3 vs.0,x2 =3.949) and less cases with deep vein thrombosis deteriorated(0 vs.8/11,x2 =5.091) in intervention group than those in control group (P < 0.05).And both the readmission rate for home care patients [2.4% (1/41) vs.36.8% (14/38),x2 =15.175] and for patients with complications [1/12 vs.43.8% (14/38),x2 =4.872] was much lower in intervention group than that in control group (both P < 0.05).Conclusion The family doctor team care can reduce the risk of complications and readmission to hospital,and also can improve the quality of life of home care disabled elderly,as well as reduce the burden of family and society.
3.The experimental animal model of hyperlipidemia and hyperlipidemic fatty liver in rats
Hongchang NI ; Jun LI ; Yong JIN ; Hongmei ZANG ; Lei PENG
Chinese Pharmacological Bulletin 1986;0(06):-
AIM To establish the hyperlipidemia and hyperlipidemic fatty liver animal model.METHODS 30 SD rats were randomized into control group (n=10)and model group(n=20).The rats of model group were fed with a standard diet and fat emulsion( 10 ml?kg -1);while the rats of control group were only fed with a standard diet.The serum TG,TC,ALT,AST,MDA,SOD and hepatic TG,TC,MDA,SOD were detected dynamically and with histologically.RESULTS The model group developed hyperlipidemia which TG and TC were elevated significantly after 1 week. 10 rats which were selected randomly in the model group were killed and the serum and liver were obtained after 2 weeks. The serum TG,TC,ALT and hepatic MDA of the model group rats were higher than the control's,while the hepatic SOD were lower. At the same time,the light degree hepatic steatosis of 2 rats were induced.The third week,both control group and model rats(n=10) were killed and the serum and the liver were obtained. Compared with the control group, the serum TG,TC,ALT,AST,MDA?SOD and hepatic TG,MDA of the model group rats were markedly higher, while the serum SOD and the hepatic SOD were significantly lower.The histopathology research showed hepatocellular macrovesicular steatosis and hepatitis in the model group. CONCLUSINOS The experimental animal model of hyperlipidemia and hyperlipidemic fatty liver in rats were successfully established for 1 week and 3 weeks fed with fat emulsion.
4.Extracorporeal shock wave therapy, joint mobilization and short wave therapy in treating scapulohumeral periarthritis
Ning ZHOU ; Bin SHOU ; Yong CHEN ; Jun PENG ; Xiang YUE
Chinese Journal of Physical Medicine and Rehabilitation 2010;32(1):38-40
Objective To compare the immediate effects of extracorporeal shock wave therapy with that of joint mobilization plus short wave therapy in treating scapulohumeral periarthritis, and to elucidate the mechanism of extracorporeal shock wave therapy and how it should be used. Methods Forty-seven patients diagnosed with scapulohumeral periarthritis were selected and randomized into two groups, a treatment group (n = 26) treated with extracorporeal shock wave therapy, and a control group ( n = 21 ) treated with joint mobilization plus short wave therapy. The short form of the McGill pain questionnaire (SF-MPQ) and range of motion (ROM) measurements were used to evaluate shoulder function. Results Compared with baseline, both groups improved significantly af-ter treatment, but the immediate effect in the treatment group was superior to that in the control group. Concln-sions As a safe, time-saving and effective therapy, extracorpnreal shock waves could be used to treat scapulo-humeral periarthritis.
5.The relationship between therapeutic effects and concentration in tissue or serum of Mel G
Chengmu HU ; Jun LI ; Yong JIN ; Lei PENG ;
Chinese Pharmacological Bulletin 2003;0(08):-
Aim To study the effects of Meloxicam gel(Mel G)on AA in rats,and the relationship between therapeutic effects and Mel G in tissue or serum. Methods The model of AA was induced by intradermal injection of Freunds complete adjuvant(FCA) in rats,the effects(hindpaw swelling volume)of Mel G on AA rats were observed following Mel G tc. A high performance liquid chromatography(HPLC)method with ultraviolet detection was set up to determine the concentration of Mel in serum and local tissue. Results Mel G significantly inhibited secondary inflammation of AA rats. The concentration of Mel G was lower in serum and higher in local tissue than that of Mel tablets. A significant linear correlation in a negative manner existed between local tissue concentration of Mel G and hindpaw swelling volume. Conclusion Therapeutic effects of Mel G on AA in rats were associated with higher tissue concentration of Mel G.
6.Locking calcaneal plate in the treatment of complicated calcaneal fractures
Wei PENG ; Xiao-Jun CAI ; Chang-Yong GUAN ;
Chinese Journal of Primary Medicine and Pharmacy 2005;0(11):-
Objective To evaluate the effects of locking calcaneal plate in the treatment of SandersⅢ~Ⅳcalcaneal fractures.Methods 15 feet of 12 patients of SandersⅢ~Ⅳcalcaneal fractures received the treatment of internal fixation reduction with locking calcaneal plate and hone graft.Results All the patients were followed up for 4 to 21 months(average 11 months) with the results that according to Maryland foot score,4 feet were reported ex- cellent,6 good,1 average and 1 poor,with total excellent and good rate of 83.3 %.Conclusion Using locking cal- caneat plate in the treatment of complicated calcaneal fractures was proved to be a good method and had satisfactory effects.
7.Auditory cerebral activation patterns of Chinese English learners by fMRI
Tong SHEN ; Zicheng HU ; Yong LI ; Yong ZHANG ; Peng XIE ; Fajin LV ; Tianyou LUO ; Jun MU
Journal of Chongqing Medical University 2008;33(Z1):55-59
Objective:To identify the cerebral activation patterns associated with the processes that occur during viewing Chinese and English words in native Chinese English learners.Methods:12 right-handed Chinese English hamers were divided into two groups equally,namely English majors and non-English majors,and took semantic judgement tasks of both English and Chinese words,for whom the fMRI images were coUected.Results:To various degrees,all subjects demonstrated activation of associated cerebral regions in both hemispheres and the left hemisphere activation was more significant for most subjects.Except for elassieal regions involved in language processing,such as Wemicke areas and Broca areas,there were other activated cerebral regions,including cerebellum,limbic system and basal ganglia nucleus,etc.To sum up,there were apparent overlap for cerebral activation distribution and no specific processing areas for both tasks.The analysis of ROI(region of interest)suggested that subjects in specialized group were more dependent on right hemisphere to perform English words task.Conclus/on:Language cognition is dominated by left hemisphere,which is also shared by the right hemisphere to various degrees and thus two hemispheres work by ways of both dissociation and coordination.It is possible that working strategy of the right hemisphere in English task is related to proficiency of the second language.A variety of distinctions are shared by each subject for language cognitive patterns.
9.Clinical Characteristics of Coronary Slow Flow in Relevant Patients
Jing WANG ; Li LI ; Yong LI ; Jianqi FENG ; Cheng PENG ; Jun DIAO ; Ji HAO ; Weiheng WU
Chinese Circulation Journal 2015;(11):1035-1038
Objective: To explore the clinical and anatomical characteristics of coronary slow lfow (CSF) in relevant patients.
Methods: We summarized the patients without coronary angiography (CAG) proved coronary stenosis (stenosis < 40%) while with TIMI indicated CSF in our hospital from 2013-01 to 2015-01. The patients were divided into 2 groups: CSF group, n=56 patients having at least 1 major coronary artery with TIMI frame counts > 27 and Control group,n=55 patients with normal coronary lfow. The related laboratory indexes were examined and relationship between MCV and CSF was studied by multi-logistic regression analysis.
Results: In CSF group, MCV 90.4 (87.48, 92.65) fL and RDW-CV 12.5 (12.30, 13.18) % were lower than those in Control group 92.3 (90.1, 94.3) fL and 13(12.7, 13.4) %,P<0.05; while MCHC 337 (332, 347) g/L and the number of left circumlfex distal braches involved 3 (2, 4) were higher than those in Control group 327.5 (322, 338) g/L and 2 (2, 3),P<0.05. Multi-logistic regression analysis showed that MCV was negatively related to CSF (partial regression coefficient= -0.138, P=0.015), Spearman rank correlation analysis presented that MCV was negatively related to TIMI frame counts (r= -0.201, P=0.009).
Conclusion: Deformability of red blood cells might be involved in pathogenesis of CSF in relevant patients.
10.Clinical effects on patients with hypertension under follow-up intervention
Yong ZHONG ; Yongping PENG ; Yunpeng YOU ; Jun WANG ; Ying WANG ; Dadong ZHENG ; Shiyong PAN
Journal of Medical Postgraduates 2016;29(4):392-394
Objective The control rate of blood pressure in hypertension patients is very low in our country , while follow-up intervention can significantly improve the situation .This study aimed to evaluate the clinical effects of anti-hypertension under follow-up intervention . Methods From October 2013 to October 2014 , 125 patients with hypertension were chose as the study objectives after first clinical anti-hypertension and were divided into intervention group (follow-up,n=65) and control group(no follow-up,n=60). Comparative analysis was made in blood pressure control , compliance with therapy and cardiovascular event incidence between the two groups after 12 weeks'intervention. Results After 12 weeks, diastolic and systolic blood pressure in intervention group was signifi-cantly lower than that in control group (P<0.05).Significant difference was also found in the compliance with drug-taking between in-tervention group and control group (73.8%vs 43.3%, P<0.01).During the follow-up period, 1 case in the control group suffered stroke and unstable angina pectoris hospitalized for treatment . Conclusion Follow-up intervention after clinical service can improve the efficacy of blood pressure control and encourage the patients to live healthy lifestyle .