1.One case of complicated chimera Klinefelter syndrome with metabolic syndrome
Li ZHAO ; Yong-De PENG ;
Chinese Journal of Endocrinology and Metabolism 2001;0(05):-
One case of Klinefelter syndrome with complicated 46,XY/47,XXY/48,XXXXY and metabolic syndrome was reported.
2.Idiopathic intracranial hypertension and eye complications
International Eye Science 2008;8(7):1307-1310
Idiopathic intracranial hypertension (IIH) is the syndrome of raised intracranial pressure (ICP) without clinical, laboratory or radiological evidence of intracranial pathology. IIH is a relatively rare disease but rapidly increasing incidence is reported due to a global increasing incidence of obesity. Disease course is generally said to be self-limiting within a few months. However, some patients experience a disabling condition of chronic severe headache and visual disturbances for years that limit their capacity to work. Permanent visual defects are serious and not infrequent complications. The pathophysiology of IIH is not fully understood yet. Advances in neuroimaging techniques have facilitated the exclusion of associated conditions that may mimic IIH. No causal treatment is yet known for IIH, and existing treatment is symptomatic and rarely sufficient. The aim of this review is to provide an updated overview of this potentially disabling disease.Theories of pathogenesis,diagnostic criteria and treatment strategies are discussed.
3.Efficacy of 23 - gauge vitrectomy cutter replaeing scissors in conventional 20 -gauge pars plana vitrectomy for severe PDR
International Eye Science 2014;(6):1159-1160
AIM: To determine whether the 23 - gauge ( 23G ) vitrecomy cutter could replace scissors in conventional 20-gauge ( 20G ) pars plana vitrectomy for treating severe proliferative diabetic retinopathy ( PDR) .
METHODS:Non-comparative interventional case series. Totally 27 eyes of 27 patients with PDR stageⅥ confirmed by funduscopy and B-ultrasound scan were enrolled. They underwent 20G vitrectomy, in which 23G vitrectomy cutter replaced scissors to remove neuvascular membrane. All 27 eyes received complete panretinal photocoagulation, 17 eyes received no tamponade, 6 eyes were 12% C3 F8 tamponade, 4 eyes were filled with silicone oil. The follow up time was 3mo. The operation duration time, iatrogenic retinal tear and retinal bleeding need electric coagulation, best corrected visual acuity ( BCVA) , retinal reattachment were analyzed.
RESULTS: The operative time was 35- 120 ( average 79-19±29. 82) min; intraoperative iatrogenic retinal breaks were detected in 2 eyes (7%). At the end of 3mo follow up, BCVA>0. 1 were in 9 eyes, from 0. 05-0. 1 in 10 eyes,<0. 05 in 8 eyes. Retinal reattached in 25 eyes (93%), still detached in other 2 eyes with silicone oil.
CONCLUSION: The 23G vitrectomy cutter could replace scissors in conventional 20G pars plana vitrectomy for treating severe PDR.
4.Heterotopic brain tissue in the orbit.
Chinese Journal of Pathology 2005;34(3):190-191
Brain
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Choristoma
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metabolism
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pathology
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surgery
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Female
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Glial Fibrillary Acidic Protein
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metabolism
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Humans
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Infant
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Neurofilament Proteins
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metabolism
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Orbit
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pathology
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surgery
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Orbital Diseases
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metabolism
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pathology
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surgery
5.Subfascial endoscopic perforating veins ablation in treating chronic venous insufficiency of lower extremities
Yong CHENG ; Yu ZHAO ; De SHI
Chinese Journal of General Surgery 2001;0(07):-
Objective To evaluate the effect of subfascial endoscopic perforating veins ablation in treating chronic venous insufficiency of lower extremities. Methods A retrospective study was carried out on 18 patients( 20 limbs) with chronic venous insufficiency treated by subfascial endoscopic perforating veins ablation. Results 69 perforating veins were detected in the medial calf of 20 limbs,including 62 incompetent perforating veins and 7 competent perorating veins. 65 perforating veins were ligated but 4 were not found.Apart from the clinical score of pigmentation, there were sigificant decreases in all the mean scores postoperatively (P
6.Changes of SCD_(14)、TNF-?、E-SLT and IL-10 level in the process of infection
Yong YANG ; Kaiyuan LUO ; De SHI
Chinese Journal of General Surgery 2000;0(11):-
Objective To investigate the changes of SCD 14, TNF-?, E-SLT and IL-10 level in the process of infection.Methods Serum E-SLT, IL-10, SCD 14 and TNF-? level was measured in 37 patients of abdominal trauma, and in model rabbits with endotoxemia.Results Serum level of SCD 14,TNF-?,E-SLT and IL-10 on the 1st to 3rd day post-op increased significantly in patients suffering from post-op infection 〔(1.61?0.47)??g/ml, (28.63?8.29)?pg/ml,(153.6?48.9)?ng/ml and (38.21?10.87)?pg/ml, compared with control, all P
7.Sequential changes of HIF-1αprotein and mRNA in hypoxic bovine retinal microvessel endothelial cells
International Eye Science 2005;5(2):225-228
● AIM: To investigate the sequential changes of HIF-1 α Protein and mRNA in hypoxic bovine retinal microvessel endothelial cells.● METHODS: The bovine retinal microvessel endothelial cells were cultured in normoxic and CoCl2-induced hypoxic conditions respectively. Expressions of HIF-1 α Protein were measured with immunohistochemical staining, and RT-PCR was used to determine the HIF-1 α mRNA.● RESULTS: HIF-1 α began to increase 1h after hypoxia,and reached the peak at 4h. After 16h, it declined significantly. Compared with the normoxic group, the expression of HIF-1 α protein in the hypoxic groups had significant difference (P<0.01), and HIF-1 α mRNA expression was unchanged under hypoxia.● CONCLUSION: HIF-1 α participates in the hypoxic procedures in retinal microvessel endothelial cells, and hypoxia induce time-dependent changes of HIF-1 α protein expression, which is not modulated on the transcription level. Analysis of HIF-1 α expression revealed a temporal and spatial changes with regard to the hyperoxic repression, indicating that HIF-1 may play a major role in the development of retinopathy of prematurity and other ischemic retinal disorders such as diabetic retinopathy.
9.Further substancial improvement of interventional diagnosis and treatment via portal vein system
Journal of Interventional Radiology 2006;0(11):-
Along with the development of interventional appliances and proficiency of operational skills,the interventional diagnosis and treatment via hepatic portal vein system have achieved great progress and improvement.However,in order to further exploit the advantages of interventional diagnosis and treatment, the review of the anatomical structures,normal aberrance of portal venous system were needed.Getting familiar with pathologic condition to discover the new interventional appliances and embolic agents,and then in term of conduct the research on a very tough substancial base in a down-to-earth manner were important.
10.Practical value of thyroid transcription factor-1 expression by immunohistochemistry in pathologic diagnosis of tumors.
Chinese Journal of Pathology 2013;42(8):566-569
Adenocarcinoma
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metabolism
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Adenoma
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metabolism
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Breast Neoplasms
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metabolism
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Carcinoma, Papillary
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metabolism
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Carcinoma, Small Cell
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metabolism
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Carcinoma, Squamous Cell
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metabolism
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Central Nervous System Neoplasms
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metabolism
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Diagnosis, Differential
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Digestive System Neoplasms
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metabolism
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Female
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Genital Neoplasms, Female
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metabolism
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Humans
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Immunohistochemistry
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Kidney Neoplasms
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metabolism
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Liver Neoplasms
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metabolism
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Lung Neoplasms
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metabolism
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Neuroendocrine Tumors
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metabolism
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Nuclear Proteins
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metabolism
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Pituitary Neoplasms
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metabolism
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Small Cell Lung Carcinoma
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metabolism
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Thyroid Neoplasms
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metabolism
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Thyroid Nuclear Factor 1
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Transcription Factors
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metabolism