Search Results

5.Apply association rules to analysis adverse drug reactions of shuxuening injection based on spontaneous reporting system data.

Wei YANG ; Yan-Ming XIE ; Yong-Yang XIANG

China Journal of Chinese Materia Medica 2014;39(18):3616-3620

This research based on the analysis of spontaneous reporting system (SRS) data which the 9 601 case reports of Shuxuening injection adverse drug reactions (ADR) in national adverse drug reaction monitoring center during 2005-2012. Apply to the association rules to analysis of the relationship between Shuxuening injection's ADR and the characteristics of ADR reports were. We found that ADR commonly combination were "nausea + breath + chills + vomiting", "nausea + chills + vomiting + palpitations", and their confidence level were 100%. The ADR and the case reports information commonly combination were "itching, and glucose and sodium chloride Injection, and generally ADR report, and normal dosage", "palpitation, and glucose and sodium chloride injection, and normal dosage, and new report", "chills, and generally ADR report, and normal dosage, and 0.9% sodium chloride injection", and their confidence level were 100% too. The results showed that patients using Shuxuening injection occurred most of ADRs were systemic damage, skin and its accessories damage, digestive system damage, etc. And most of cases were generally and new reports, and patients with normal dosage. The ADR's occurred had little related with solvent. It is showed that the Shuxuening injection occurred of ADR mainly related to drug composition. So Shuxuening injection used in clinical need to closely observation, and focus on the ADR reaction, and to do a good job of drug risk management.
Adverse Drug Reaction Reporting Systems ; Drug-Related Side Effects and Adverse Reactions ; diagnosis ; Drugs, Chinese Herbal ; adverse effects ; Female ; Humans ; Male

1.Factors of individual differences in olfactory function.

2.Analysis of genes and genetic susceptibility of olfactory disorders.

3.Evaluation of therapeutic efficacy of olfactory disorders with glucocorticoid.

4.Interaction between trigeminal system and olfaction.

5.Apply association rules to analysis adverse drug reactions of shuxuening injection based on spontaneous reporting system data.

6.Data collection technology of digital otorhinolaryngology.

7.Application of proteomic techniques in pediatric research.

8.Advances in primary ciliary dyskinesia.

9.Preliminary study on in vivo whole cell recording technique in anesthetized rat.

10.Extraskeletal Ewing's sarcoma: a report of 2 cases.

Display Mode

Output Records

File Type