Clinical observation on vesicoureteral reflux following renal tuberculosis were obtained 46 cases of renal tuberculosis seen at N. P. H. during the period from April 1971 to April 1975. 1) Demonstrable vesicoureteral reflux were 27 cases with cystogram, voiding cystogram, retrograde cystogram and I. V. P. 2) Retrograde cystogram showed a highest peak in occurrence of vesicoureteral reflux. 3) The incidence of bladder Tb. and vesicoureteral reflux secondary to renal Tb. among these patients, in 50% of the cases occurred from marked contracted bladder and 2% from the bladder having normal capacity. In the presence of renal Tb. and vesicoureteral reflux mentioned above, the most frequent observable change was in marked contracted bladder, and it showed that their incidence were increased by severity of extent of bladder contraction.
Humans ; Incidence ; Reflex* ; Tuberculosis ; Tuberculosis, Renal* ; Urinary Bladder ; Vesico-Ureteral Reflux

No abstract available.
Humans ; Outpatients* ; Silicon Dioxide*

PURPOSE: In adriamycin(ADR)-induced cardiomyopathy, several different mechanisms are suggested. However, little information is available regarding the role of apoptosis. In the present study, we examined the induction of apoptosis on ADR treatment and anti-apoptotic effects of probucol, a lipid-lowering drug, and we also studied the changes of bcl-2 expression in order to see the molecular mechanisms underlying the effect of probucol. METHODS: Cardiac myocytes were isolated from 3-day-old rats, and cultured in low(1 pM) or high doses(10pM) of ADR for 24 hours. Probucol(50 pM) was added 30 minutes before ADR administration. Apoptosis was determined by TUNEL staining, and bcl-2 expression was estimated by immunocytochemistry. RESULTS: The number of TUNEL-positive cells significantly increased in both groups treated with ADR. However, anti-apoptotic effect of probucol was evident only in low dose. In addition, the expression of bcl-2 was significantly increased only in the low-dose ADR treatment group and its expression was inhibited by pretreatment of probucol. CONCLUSION: These results suggest that apoptosis might play an important role in ADR-induced cardiotoxicity, and ADR-induced apoptosis was partially prevented by pretreatment of probucol. And ADR-induced apoptosis was not related with depression of bcl-2. Additionally, inhibition of bcl-2 gene expression of low-dose ADR treatment group by probucol suggests that another cell survival mechanism could be implicated in the action of probucol. (J Korean Pediatr Soc 2000;43:746-754)
Animals ; Apoptosis* ; Cardiomyopathies ; Cell Survival ; Depression ; Doxorubicin ; Genes, bcl-2 ; Immunohistochemistry ; In Situ Nick-End Labeling ; Myocytes, Cardiac* ; Probucol* ; Rats*

No abstract available.
Krukenberg Tumor*

No abstract available.
Mouth* ; Neurilemmoma*

No abstract available in English.
Amputation

Animals ; Body Weight ; Fluorouracil ; Hair ; Rats ; Rats, Sprague-Dawley

No abstract available.
Child* ; Humans ; Lupus Erythematosus, Systemic*

No abstract available.
Sinusitis*

No abstract available.
Dust* ; Mastoid*