1.A Case of Albright's Syndrome.
Korean Journal of Dermatology 1984;22(1):111-115
Albright's syndrome consists of large pigmented macules of the skin and fibrodysplasia of the bones. The full syndrome with precocious puberty occurs particularly in girls. Other endocrinopathies including Cushing syndrome, hyperthyroidism and acromegaly can be accompanied. A case of Albright's syndrome is reported. The patient was a 4-year-old male child, who was born with multiple, dark brownish, irregularly bordered macules on the trunk and extremities. Deformities of facial skeleton and limping gait were noticed at the age of 2 years. He had pathological fractures twice, at the age of 3 and 4 years, respectively, due to fibrodysplasia of both femur bones. Especially, involvement of the sphenoid bones caused compression of the optic nerves and diminished vision of both eyes. On radiologic examinations, polyostotic fibrous dysplasia were noticed on the humerus, scapula, femur, tibia, fibula, pelvis, vertebra and skull base. The level of alkaline phosphatase was highly elevated.
Acromegaly
;
Alkaline Phosphatase
;
Child
;
Child, Preschool
;
Congenital Abnormalities
;
Cushing Syndrome
;
Extremities
;
Female
;
Femur
;
Fibrous Dysplasia, Polyostotic*
;
Fibula
;
Fractures, Spontaneous
;
Gait
;
Humans
;
Humerus
;
Hyperthyroidism
;
Male
;
Optic Nerve
;
Pelvis
;
Puberty, Precocious
;
Scapula
;
Skeleton
;
Skin
;
Skull Base
;
Sphenoid Bone
;
Spine
;
Tibia
;
Vision, Low
2.A study on the chemotactic activity of the peripheral blood neutrop- hils in acne patients to the cytosol antigen of propionibacterium acnes.
Korean Journal of Infectious Diseases 1991;23(1):35-38
No abstract available.
Acne Vulgaris*
;
Cytosol*
;
Humans
;
Propionibacterium acnes*
;
Propionibacterium*
3.Malignant Schwannoma.
Hyang Joon PARK ; Yong Woo CINN
Korean Journal of Dermatology 1986;24(1):159-163
Malignant schwannoma is a malignant neoplasm of nerve sheath origin. It develops in an unaltered nerve or in a neurofibroma, and rarely, if ever, within a neurilernmoma. We experienced a malignant schwannoma in a 75-year-old man without von Recklinghausen's syndrome. The lesion was solitary and polypoid, fungating nodule in the posterior portion of the left thigh, The tumor cells had some features of Schwann cells and positively stained to S-100 protein and neuron-specific enolase. Complete excision was performed but the associated nerve could not be demonstrable.
Aged
;
Humans
;
Neurilemmoma*
;
Neurofibroma
;
Phosphopyruvate Hydratase
;
S100 Proteins
;
Schwann Cells
;
Thigh
4.Two Cases of Piroxicam-Induced Photoallergic Dermatitis.
Hyang Joon PARK ; Yong Woo CINN
Korean Journal of Dermatology 1986;24(2):283-287
Piroxicam is a new nonsteroidal anti-inflammatory drug(NSAID) and widely used in the management of rheumatoid arthritis and osteaorthritis. We experienced. two cases of photosensitive dermatitis developed while taking piroxicam. Both had pruritic and eczematous skin lesions on sun-exposed areas and showed positive reactions to 0. 1 % piroxicam solution in photopatch test in contrast with control group, which suggest a photoallergy mechanism. To our knowledge, these are the first reported cases in the Korean literature.
Arthritis, Rheumatoid
;
Dermatitis
;
Dermatitis, Photoallergic*
;
Piroxicam
;
Skin
5.Clinical and Histophthologic Review in Patients with Henoch: Schonlein Purpura.
Joo Young ROH ; Yong Woo CINN ; Soo Nam KIM
Korean Journal of Dermatology 1988;26(4):536-543
Authors review the clinical and histopathologic findings of 41 EIenoch-Schonlein purpur.a patients and attempt, to clarify the association between abnorma] urinary findings and anti-streptolysin 0(ASLO) titer and performed the direct immunofluorescence(',E)II) study on skin lesion to investigate the pathogenetic mechanim of renal involvement. The results were summarized as follows : 1. Ag(, distribution was form 3 month to 63 years and mean age was 18.9 years. male to female ratio was 1.2:1(22 males '. 19 females). 2. In he past history, there were preceding upper respora.tory infections in 25(61:o)patients and drug history in 10(24.3%)patients. 3. (linical manifestations in the order of frequency were as follows : arthralgia (60.9%), hematuria or albuminuria(43.8%), abdominal pain(21.9%), and positive occult: blood test(7.3%)in stool examination. 4. In the laboratory fiindings, leukocytosis was cleveloped in 14.6%, anemia in 2.4%, increased eryttrocyte sec1imentation zate in 12.3% increased ASLG titer in 43.9% of patients, and serum IgG was increased in 4 of 20(20.6)patierits, IgA in 4 of 21(19%)patients, IgM in 1fo 19(5.3o)patients. 5. Because correlation between increased A.LO titer ancl ahnoormal urinary findings wa.s high(x-test, p< 0.0,5), increased ASI,O titer may be inclicator of renal involvement. 6. DIF stuc].y was per formed in 34 patients. All showed positive reactiviy. IgG(17%), IgA(29.4% ), Clq(14.6%), C3(12.2% ), fibrinog.n(82.4%) were deposited around the vessel wall in a granular pattern. 7. There was statistically significant increase in mean serum IgG value in patients with abnormal urinary findings( t test, p < 0.05 ).
Anemia
;
Arthralgia
;
Female
;
Hematuria
;
Humans
;
Immunoglobulin A
;
Immunoglobulin G
;
Immunoglobulin M
;
Leukocytosis
;
Male
;
Purpura*
;
Purpura, Schoenlein-Henoch
;
Skin
6.A Case of Forehead Plaque as an Initial Sign of Tuberous Sclerosis.
You Chan KIM ; Jeong Hwa LEE ; Yong Woo CINN
Korean Journal of Dermatology 1995;33(1):201-205
Tuberous sclerosis is a systemic disorder of hamartoma format on includes facial angiofibromas, subungal fibromas, hypomelanic maciles Shagreens patches. The earliest skin manifestation of tuberous sileiule, but it may appear later. We present a case of fibrous plaqu a recognized skin signs. Forehead plaque can be the earliest skin near in many organs. Skin involvement less forehead fibrous plaques, and vsis is usually hypornelanotic inacipearing before any of these more festation of tuberous sclerosis. Its presence may lead to early diagnosis and appropriate genetic couise hng hut may be a poor prognostic sign.
Angiofibroma
;
Early Diagnosis
;
Fibroma
;
Forehead*
;
Hamartoma
;
Skin
;
Skin Manifestations
;
Tuberous Sclerosis*
7.A Case of Eyelid oil Granuloma Caused by High Pressure Injury.
You Chan KIM ; Yong Woo CINN ; Jeong Hwa LEE
Korean Journal of Dermatology 1995;33(1):197-200
Oil granuloma is a foreignbody reaction which occurs after injection of lipid usually for cosmetic or therapeutic reasons. I present a case of eyelid oil granuloma caused by accidental high pressure injury in a 39-year-old man. The patient had a 2 x 0.5cm sized, firm, normardear subcutaneous nodule on the Rt. upper eyelid. Histopathologic examination showed a characteris swiss-cheese appearance. Eyelid oil granuloma caused by high pressure injury is very rare and my case is the first described in Korean medical literatures.
Adult
;
Eyelids*
;
Granuloma*
;
Humans
8.Atypical Fibroxanthoma of the Skin.
Hyang Joon PARK ; Yong Woo CINN ; Soo Nam KIM
Korean Journal of Dermatology 1986;24(1):155-158
An immunohistochemical and electron microscopic study of an atypical fibroxanthoma of the skin (AFX) was reported. The lesion developed on the left scapulararea in a 70-year-old man. The result using antibody to S-100 protein was negative and the tumor cells observed with electron microscope were undifferentiated, fibroblast-like, histiocyte-like and multinucleated giant cells. But Langerhans-like cells or Langerhans were not found.
Aged
;
Giant Cells
;
Humans
;
S100 Proteins
;
Skin*
9.Two Cases of Nodular-cystic Fat Necrosis.
You Chan KIM ; Hyang Joon PARK ; Yong Woo CINN
Annals of Dermatology 2001;13(1):59-61
Nodular-cystic fat necrosis is an unusual, distinctive entity characterized by histologically en-capsulated fat necrosis in the subcutis. We report two cases of nodular-cystic fat necrosis. The lesions were subcutaneous nodules. Histopathologically, the nodules showed strong periodic acid-Schiff -positive necrotic adipose tissue with lipomembranous changes and calcification.
Adipose Tissue
;
Fat Necrosis*
10.A Study of Minimal Inhibitory Concentrations of Several Kind of Drugs against Pityrosporum orbiculare.
Young Chul KYE ; Yong Woo CINN ; Soo Nam KIM
Korean Journal of Dermatology 1983;21(2):179-187
The bacteria as well as the fungi can build up resistance against different kinds of drugs or can decrease in sensitivity to these drugs. Therefore it is necessary that we use the MIC test for acertain period of time to determine the right concentration of drug to use in therapy. The culturing of P. orbiculare was successful in 1951. Up until that time, there were few drugs available to use in the MIC test. So, treatment for Tinea versicolor was dependent upon ones previous experience in determining the drug's effective concentration. Therefore, we performed the MIC test of clotrimazole, sodium thiosulfate, selenium sulfide, propylene glycol against P. orbiculare. The diagnos is for Tinea versicolor in the patient was confirmed by using KOH smear and by the clinical manifeststion. The fungi were then isolated in a culture from an olive oil rich media Mixture of isolated fungus and olive oil was applied to the lateral side of a healthy male's right upper extremity. After one week, P. orbiculare was confirmed by wood lamp examination, KOH smear and culture. After confirmation of P. orbiculare, a variety of concentrated drugs were used. Then media, containing propylene glycol, sodium thiosulfate, selenium sulfide and clotrimazole with a small amount of olive oil was used in inoculations of 10 viable unit/ml of P.orbiculare in attempt to estblish the MIC test. Test results are as follows: l) Propylene glycol MIC Range; 12. 5mg/ml~7. 5mg/ml. 2) Sodium thiosulfate MIC Range; 500mg/ml~7. 5mg/ml. 3) Selenium sulfide MIC Range; l. 25mg/ml~0. 04mg/ml. 4) Clotrimazole MIC Range; 0. 5mg/ml~ 0. 0005mg/ml.
Bacteria
;
Clotrimazole
;
Fungi
;
Humans
;
Malassezia*
;
Olea
;
Propylene Glycol
;
Selenium
;
Sodium
;
Tinea Versicolor
;
Upper Extremity
;
Wood
;
Olive Oil