No abstract available.
Uterine Prolapse*

With the aim of gaining more insight into the catecholaminergic system in the nervous system of the rat, we have studied the precise distribution pattern of the tyrosine hydroxylase immunoreactive[TH-IR] fibers and soma in the spinal cord and dorsal root ganglion. In the dorsal root ganglion[DRG], TH-IR fibers were observed to run along the vessel wall, spirally and not found in the neural tissue itself. A few TH-IR fibers were found in the spinal nerve, not in the ventral root. Many TH-IR neurons were distributed in the L3, 4, 5, and 6 DRG but none of them were found in the other DRG segments. In the spinal cord, TH-IR fibers have shown sparse distribution all over spinal cord but relatively dense distribution in the ventral horn, intermediolateral column, lamina I of the dorsal horn of the cervical, lumbar, sacral, and coccygeal segment. TH-IR neurons were found in the intermediolateral column, dorsal gray commissure, dorsal horn of the C1 and C2 segments and S1-4 segments. TH-IR neurons in the cervical segments were polygonal and spindle shaped with well developed processes. In contrast to this, TH-IR neurons in the sacral segments were oval or spindle shaped with no processes. In conclusion, neurons in the DRG were not influenced by catecholaminergic nervous input. Intrinsic catecholaminergic nervous systems were found in both of spinal cord and DRG.
Animals ; Carisoprodol ; Diagnosis-Related Groups ; Ganglia, Spinal* ; Horns ; Immunohistochemistry ; Nervous System ; Neurons ; Rats* ; Spinal Cord* ; Spinal Nerve Roots* ; Spinal Nerves ; Tyrosine 3-Monooxygenase ; Tyrosine*

No abstract available.

Accidents, Traffic ; Diagnosis ; Facial Injuries ; Female ; Head ; Humans ; Incidence ; Inpatients ; Jeollanam-do ; Lacerations ; Male ; Mandibular Fractures ; Neck ; Postoperative Complications ; Social Environment ; Surgery, Oral ; Violence

A 10-year-old boy presented with dribbling on urination, intermittent left flank pain and pyuria since birth. With voiding cystourelhrography this case was diagnosed as congenital anterior urethral valve which was confirmed by panendoscopic study. He was underwent electrocoagulation of the valve and left nephrectomy. And so he was discharged with good urinary stream on the 23 rd postoperative day.
Child ; Electrocoagulation ; Flank Pain ; Humans ; Male ; Nephrectomy ; Parturition ; Pyuria ; Rivers ; Urination

BACKGROUND: Gerstmann-Straussler-Scheinker disease (GSS) is a type of human transmissible spongiform encephalopathy (TSE) that is determined genetically. CASE REPORT: A 46-year-old woman presented with a slowly progressive ataxic gait and cognitive decline. She was alert but did not cooperate well due to severe dementia and dysarthria. High signal intensities in the cerebral cortices were evident in MRI, especially in diffusion-weighted images (DWI). A prion protein gene (PRNP) analysis revealed a P102L (proline-to-leucine) mutation in codon 102. CONCLUSIONS: This is the first reported case of GSS (confirmed by PRNP analysis) in Korea. Distinctive MRI findings are also presented.
Cerebral Cortex ; Codon ; Dementia ; Dysarthria ; Female ; Gait ; Gerstmann-Straussler-Scheinker Disease ; Humans ; Korea ; Middle Aged ; Prion Diseases

BACKGROUND: Radiation pneumonitis(RP) is the major serious complication of thoracic irradiation treatment. In this study, we attempted to retrospectively evaluate the long-term prognosis of patients who experienced acute RP and to identify factor that might allow prediction of RP. METHODS: Of the 114 lung cancer patients who underwent thoracic radiotherapy between December 2000 and December 2002, We performed analysis using a database of 90 patients who were capable of being evaluated. RESULTS: Of the 44 patients(48.9%) who experienced clinical RP in this study, the RP was mild in 33(36.6%) and severe in 11(12.3%). All of severe RP were treated with corticosteroids. The median starting corticosteroids dose was 34 mg(30~40) and median treatment duration was 68 days(8~97). The median survival time of the 11 patients who experienced severe RP was significantly poorer than the mild RP group. (p=0.046) The higher total radiation dose(>or=60 Gy) was significantly associated with developing in RP.(p=0.001) The incidence of RP did not correlate with any of the ECOG performance, pulmonary function test, age, cell type, history of smoking, radiotherapy combined with chemotherapy, once-daily radiotherapy dose fraction. Also, serum albumin level, uric acid level at onset of RP did not influence the risk of severe RP in our study. CONCLUSION: Only the higher total radiation dose(>or=60 Gy) was a significant risk factor predictive of RP. Also severe RP was an adverse prognostic factor.
Adrenal Cortex Hormones ; Drug Therapy ; Humans ; Incidence ; Lung Neoplasms* ; Lung* ; Prognosis ; Radiation Pneumonitis* ; Radiotherapy ; Respiratory Function Tests ; Retrospective Studies ; Risk Factors ; Serum Albumin ; Smoke ; Smoking ; Uric Acid

BACKGROUND: Thoracic sympathetic block surgery is a safe and effective procedure for palmar hyperhydrosis, and this maintains sufficient moisture and prevents compensatory hyperhidrosis. To avoid compensatory hyperhidrosis, the authors performed sympathetic block surgery just above the R4 level to maintain sympathetic tone affecting the caudal area. MATERIAL AND METHOD: A total of 71 subjects (45 males and 26 females) were categorized into two groups. Group 1 (31 patients, mean age: 25.5 years) had clips placed both on the upper and lower part of R4 sympathetic ganglion, and group 2 (40 patients, mean age: 25.9 years) underwent clipping of the upper part of R4. Telephone surveys were done to collect data on 8 categories, and the average follow up interval was 24.9 months (group 1) and 18.9 months (group 2). RESULT: For group 1, 41.9% experienced no sweating and 48.4% replied they experienced some sweating depending on the surrounding conditions. Group 2 showed that 60% experienced no sweating and 35% replied they experienced some sweating depending on the surrounding conditions. 58.1% in group 1 experienced sweating right after the surgery, and 40.0% in group 2 experienced the same. Group 1 (38.1%) and group 2 (37.5%) replied they experienced no hand dryness and more patients in group 2 than in group 1 had hand dryness, but without uncomfortable symptoms. 71.0% (group 1) and 62.5% (group 2) replied they had no compensatory hyperhidrosis or related symptoms. One patient in group 1 and two in group 2 reported they regretted undergoing the procedure. The regions of compensatory hyperhidrosis were the back, thigh and chest in group 1 and the group 2 reported the back, chest, and abdomen in the order of frequency. Fewer incidences of the gustatory hyperhidrosis were noted in group 2. Most of the patients were satisfied with their treatment. CONCLUSION: Clipping the upper part of the R4 ganglion or R4 sympathetic block are both effective for treating palmar hyperhidrosis and these treatments decrease the occurrence or symptoms of compensatory hyperhidrosis. The upper R4 sympathetic block procedure is easier and safer with fewer incidences of gustatory hyperhidrosis and a higher percentage of patient satisfaction.
Abdomen ; Endoscopy ; Follow-Up Studies ; Ganglia, Sympathetic ; Ganglion Cysts ; Hand ; Humans ; Hyperhidrosis* ; Incidence ; Male ; Patient Satisfaction ; Reflex ; Sweat ; Sweating ; Sweating, Gustatory ; Sympathetic Nervous System ; Telephone ; Thigh ; Thorax

Skin metastases from internal cancers are unusual; from a hepatoma they are extremely rare. The most common clinical presentation are solitary or multiple nodules that have appeared in one area of the body. Other forms include inflammatory and sclerodermoid metastatic growths. Case one was a 54-year-old male who had had partial hepatectomy of the right lobe of his liver following diagnosis of hepatocellular carcinoma five years ago. He presented with a 10 month history of a solitary nodule on the chin. Another case was a 46-year-old male, who had developed hepatocellular carcinoma forming a large subcutaneous mass by hemat,ogenous metastasis of the left zygomatic bone, masseter muscle and subcutaneous fat. Additional metastases were observed in the portal vein and multiple bones including the right shoulder, the 1st, 2nd, 3rd sacral spine and the right 3rd, 7th rib. In view of the clinical and histopathologic findings both skin tumors were considered to originate from the liver. The skin metastases may be indicative of progression by the primary tumor and also the first indication that a malignant tumor has not been eradicated.
Carcinoma, Hepatocellular* ; Chin ; Diagnosis ; Hepatectomy ; Humans ; Liver ; Male ; Masseter Muscle ; Middle Aged ; Neoplasm Metastasis* ; Portal Vein ; Ribs ; Shoulder ; Skin ; Spine ; Subcutaneous Fat

BACKGROUND: Hyperlipidemia is the one of the major risk factors causing the atherosclerosis of coronary arteries. Treatment of hyperlipidemia with drugs has been confirmed the effects of therapy showing a decreased incidence of coronary artery disease. Simvastatin is a new drug of HMG-CoA reductase inhibitors and the short-term hypolipidemic effects and safety of simvastatin is evaluated in patients with hyperlipidemia. METHODS: We studied 63 patients (39 males and 24 females, mean age 58) for 12 weeks whose plasma levels of total cholesterol were higher than 240 mg/dL or higher than 220 mg/dL with ischemic heart disease. Simvastatin was administered 20 mg/day and measured lipid profile at 12 week interval. RESULT: 1)Simvastatin significantly reduced the level of the plasma total cholesterol(-29.3%), LDL- cholesterol(-36.9%) and triglyceride(-13%)(p<0.05) but the level of HDL-cholesterol was not changed after 12 weeks simvastatin therapy. 2)the clinical symptoms and laboratory examination before and after simvastatin treatment showed no particular abnormal findings in short term follow up. CONCLUSION: These results suggested that short-term simvastatin therapy in patients with hyperlipidemia seeems to be very effective and safe.
Atherosclerosis ; Cholesterol ; Coronary Artery Disease ; Coronary Vessels ; Female ; Follow-Up Studies ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Hyperlipidemias* ; Incidence ; Male ; Myocardial Ischemia ; Plasma ; Risk Factors ; Simvastatin