1.p53-mediated HIV-1 Tat Suppression is Likely to be Assaciated with duble-stranded RNA-dependent Protein Kinase, PKR.
Jung Whan KIM ; Hee Sun BYUN ; Yong Soo BAE
Journal of the Korean Society of Virology 1999;29(4):235-245
No abstract available.
eIF-2 Kinase*
;
HIV-1*
;
Phosphorylation
2.Operative Treatment of the Bony Mallet Finger.
Bum Soo KIM ; Sung Do CHO ; Yong Sun CHO ; Tae Woo PARK ; Jae Yong BYUN
The Journal of the Korean Orthopaedic Association 1998;33(2):416-422
Although there are various methods of operative treatment for hony mallet finger, the operative technique is not so easy and complications such as joint stiffness, sott tissue prohlems, infection, change of nail shape and arthrosis are common. The authors performed operations for 26 cases of hony mallet fingers, fixing the hony frapment by Kirschner wire, pull-out wire suture and miniscrew respectively, from Jan. l988 to Jun. l996. The results were as follows. l. According to Niechajev's classification. there were 3 cases of type B, 7 cases of type C, l4 cases of type D, and 2 cases of type E. And 11 cases were accompanied hy crushing injury. 2. Involved fingers were third finger in 11cases, fit'th finger in 7 cases, fourth finger in 5 cases, second finger in 2 cases. and thumb in I case. 3. The hony mallet finger was caused hy occupational injury in l6 cases, direct blow in 7 cases and sports injury in 3 cases. 4. The fractured fragment was fixed hy Kirschner wire in 9 cases, by pull-out suture in 9 cases and by miniscrew in 8 cases. 5. The results were evaluated hy Kanies scale. Sixteen cases had satisfactory results. Seven cases (87.5%) were satisfactory in miniscrew fixations. 5 cascs (55.6%) in pull-out wire suture methocls and 2 cases (22.2%) in Kirschner wire tixations. 6. The complications were joint incongruity in 4 cases, dorsal prominece in 6 cases, painful limitation of motion in 2 cases which were treated by arthrodesis, pin site infection in 2 cases and hreakage of wire suture in 1 case. 7. The miniscrew fixation offered relatively firm fixation, low complication rate, and good results. so it can be considered as one of the good methods of treatment for hony mallet finger.
Arthrodesis
;
Athletic Injuries
;
Classification
;
Fingers*
;
Joints
;
Occupational Injuries
;
Sutures
;
Thumb
3.The cervical spinal fractures : comparison of the sites and incidences according to the causes and the types of the injuries.
Jae Ho CHO ; Kil Ho CHO ; Woo Mock BYUN ; Sun Yong KIM ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1993;10(1):114-126
The fractures of the cervical spine are relatively uncommon, but they may cause serious neurologic deficits temporarily or permanently. So, it is very important to treat the patients early by way of exact evaluation for the sites and the mechanisms of the injuries. The authors reviewed retrospectively 188 cervical spinal fractures in 100 patients from Sep. 1984 to Aug. 1990. Commonly involed levels were C5 and C6 in lower cervical level and C2 in upper cervical level and the sites in each spine were body; lamina and odontoid process. The hyperflexion injury was the most common type of the cervical spinal fractures occupying 53% of all cervical fractures and cause more multipe fractures(2.26 fractures/patient) than in hyperextension (1. 68 fractures/patient). In hyperflexion injuries, body, transverse and spinous process were commonly involved but lamina fracture was relatively common in hyperextension injury. The dislocations associated with fractures were developed most commonly in hyperflexion injury and 70% of these were anterior dislocation and the most commonly involved levels were C5-6 and C6-7. In conclusion, hyperflexion injury needs more close examination for the entire spinal levels than injuries of other mechanisms because it results in more severe fractures with or without dislocation and relatively frequent multiple fractures in different levels.
Dislocations
;
Humans
;
Incidence*
;
Neurologic Manifestations
;
Odontoid Process
;
Retrospective Studies
;
Spinal Fractures*
;
Spine
5.MR imaging of internuclear ophthalmoplegia due to cerebrovascular diseases.
Suk Hee KIM ; Young Ki LEE ; Jung Sang HAH ; Young Ju BYUN ; Choong Suh PARK ; Sun Yong KIM
Yeungnam University Journal of Medicine 1991;8(1):220-230
Internuclear ophthalmoplegia is a conjugated gaze disorder characterized by impaired adduction on the side of a lesion involving the medial longitudinal fasciculus with dissociated nystagmus of the other abducting eye. Six patients with INO (who had clinical cerebrovascular diseases) underwent MR imaging and the results were as follows: 1. The MLF lesions were identified by MR imaging in 5 cases 2. The ratio of unilateral INO to bilateral INO was 5:1 3. The nature of lesions was infarction in 4 cases and hemorrhage in 1 case 4. The sites of MLE lesion were in the midbrain in 4 cases and in the pons in 1 case 5. All 5 cases of INO identified by MR imaging had other lesion sites in addition to MLE lesion.
Cerebrovascular Disorders*
;
Hemorrhage
;
Humans
;
Infarction
;
Magnetic Resonance Imaging*
;
Mesencephalon
;
Nystagmus, Pathologic
;
Ocular Motility Disorders*
;
Pons
6.The Efficacy of Recombinant Human Follicle Stimulating Hormone (rhFSH) in Human IVF-ET Program.
Kuk Sun HAN ; Hong Bok LEE ; In Ok SONG ; Yong Seog PARK ; Hye Kyung BYUN ; Jin Hyun JUN ; Mi Kyoung KOONG
Korean Journal of Fertility and Sterility 2002;29(1):45-56
OBJECTIVES: Recently, recombinant FSH (rFSH) has been manufactured using a Chinese hamster ovary cell line transfected with the gene encoding human FSH. Both rFSH and urinary gonadotropin (uFSH) could be used for controlled ovarian hyperstimulation (COH). However, uFSH implies a number of disadvantages, such as batch-to-batch inconsistency, no absolute source control, dependence on large amounts of urine, low specific activity, and low purity. The purpose of this study was to evaluate the efficacy of rFSH in human IVF-ET program. MATERIALS AND METHODS: A total of 508 infertile women was enrolled in this study. They are classified into rFSH group (n=177) or uFSH group (n=331), and all of them were matched by age and cause of infertility in same period. The Puregon(R) (Organon, Holland) was used as rFSH, and the Metrodin-HP(R) (Serono, Switzeland) and Humegon(R) (Organon, Holland) was used as uFSH. We subdivided the patients into three age groups. The outcomes of IVF-ET program were analyzed using the statistical package for social sciences (SPSS). RESULTS: There was no significant differences in the level of estradiol on hCG injection day, the numbers of retrieved oocytes, matured oocytes, fertilized oocytes, transferred embryos, frozen embryos between the two groups. The total dose (IU) of gonadotropin for COH was significantly lower in the rFSH group compared to uFSH group (1339+/-5491.1 vs 2527.8+/-1075.2 IU, p<0.001). Clinical pregnancy rate per embryo transfer in the rFSH group showed increasing tendency, compared to the uFSH group, but there was no statistical significance (35.2% vs 29.3%). Our results demonstrated that the relative efficiency of rFSH compared with uFSH is higher in older patients. CONCLUSIONS: The ovarian stimulatory effect and clinical outcome of recombinant FSH was similar to that of the urinary gonadotropin. The IVF-ET cycles with significantly lower dose of gonadotropin in rFSH group showed comparable results. Therefore, we suggest that recombinant FSH is more potent and effective than urinary gonadotropin.
Animals
;
Cell Line
;
Cricetinae
;
Cricetulus
;
Embryo Transfer
;
Embryonic Structures
;
Estradiol
;
Female
;
Follicle Stimulating Hormone, Human*
;
Gonadotropins
;
Humans*
;
Infertility
;
Oocytes
;
Ovary
;
Pregnancy Rate
;
Social Sciences
7.A Case of Persistent Cow's Milk Allergy Accompanying Atopic Dermatitis.
Yong Se CHO ; Sook Young PARK ; Yong Won CHOI ; Jee Hee SON ; Yun Sun BYUN ; Bo Young CHUNG ; Hee Jin CHO ; Hye One KIM ; Chun Wook PARK
Korean Journal of Dermatology 2017;55(9):619-620
No abstract available.
Dermatitis, Atopic*
;
Food Hypersensitivity
;
Milk Hypersensitivity*
;
Milk*
8.Herpes Simplex Encephalitis Suffered Rotatory Dizziness as a Primary Symptom
Sun A CHOI ; Jae Yong BYUN ; Sun Kyu LEE
Journal of the Korean Balance Society 2013;12(2):67-71
Herpes simplex encephalitis (HSE) is rare, serious sporadic encephalitis associated with high mortality in untreated cases. Although cognitive impairment with fever could be the clue of diagnosis, various symptoms can make it difficult to be diagnosed. Dizziness is one of the most frequent symptoms ENT doctors can encounter. Authors experienced the HSE patient suffered rotatory sense of dizziness as a primary symptom and treated the patient successfully without major complication. We reported our experience and findings of vestibular function test of patient. It could be helpful to other ENT doctors who encounter similar patients.
Dizziness
;
Encephalitis
;
Encephalitis, Herpes Simplex
;
Fever
;
Herpes Simplex
;
Humans
;
Methylmethacrylates
;
Polystyrenes
;
Vestibular Function Tests
9.Evaluation of Deep Vein Thrombosis with Multidetector Row CT after Orthopedic Arthroplasty: a Prospective Study for Comparison with Doppler Sonography.
Sung Su BYUN ; Jeong Ho KIM ; Youn Jeong KIM ; Yong Sun CHUN ; Chul Hi PARK ; Won Hong KIM
Korean Journal of Radiology 2008;9(1):59-66
OBJECTIVE: This prospective study evaluated the ability of indirect 16-row multidetector CT venography, in comparison with Doppler sonography, to detect deep vein thrombosis after total hip or knee replacement. MATERIALS AND METHODS: Sixty-two patients had undergone orthopedic replacement surgery on a total of 30 hip joints and 54 knee joints. The CT venography (scan delay time: 180 seconds; slice thickness/increment: 2/1.5 mm) and Doppler sonography were performed 8 to 40 days after surgery. We measured the z-axis length of the beam hardening artifact that degraded the image quality so that the presence of deep vein thrombosis couldn't be evaluated on the axial CT images. The incidence and location of deep vein thrombosis was analyzed. The diagnostic performance of the CT venograms was evaluated and compared with that of Doppler sonography as a standard of reference. RESULTS: The z-axis length (mean +/- standard deviation) of the beam hardening artifact was 4.5 +/- 0.8 cm in the arthroplastic knees and 3.9 +/- 2.9 cm in the arthroplastic hips. Deep vein thrombosis (DVT) was found in the popliteal or calf veins on Doppler sonography in 30 (48%) of the 62 patients. The CT venography has a sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 90%, 97%, 96%, 91% and 94%, respectively. CONCLUSION: The ability of CT venography to detect DVT was comparable to that of Doppler sonography despite of beam hardening artifact. Therefore, CT venography is feasible to use as an alternative modality for evaluating post-arthroplasty patients.
Adult
;
Aged
;
Aged, 80 and over
;
*Arthroplasty, Replacement, Hip
;
*Arthroplasty, Replacement, Knee
;
Artifacts
;
Female
;
Humans
;
Leg/*blood supply
;
Male
;
Middle Aged
;
Predictive Value of Tests
;
Prospective Studies
;
Sensitivity and Specificity
;
Tomography, X-Ray Computed/*methods
;
Venous Thrombosis/etiology/*radiography/*ultrasonography
10.The Effect of Cryotherapy in Hailey-Hailey Disease.
Jee Hee SON ; Yong Se CHO ; Yun Sun BYUN ; Bo Young CHUNG ; Chun Wook PARK ; Hye One KIM
Annals of Dermatology 2017;29(1):117-118
No abstract available.
Cryotherapy*
;
Pemphigus, Benign Familial*