The normal vascularization of peripheral nervesand the vascular factor in peripheral nerve les ons have regained increasing interest among surgeons. So, several attempts have been made to assess the relative importance of the vasa nervorum and intrinsic longitudinal vascular plexuses of nerve in maintaining the blood supply.of a segment of nerve trunk. The purpose of our experiment was to determine in laboratory animals the maximum extent to which a nerve can be mobilized without impairing its vascular supply so much that nerve function is jeopardized. All our studies were carried out on both sides of the sciatic-tibial nerve of thirty-two rabbit which were anesthetized intraperitoneally with urethane. The experimental procedure differed in three groups, Group I in which the sciatic nerve was mobilized 3 cm in length, Group II was mob lized 7 cm length and Group III was mobilized 10cm long. The tibialis post. muscles of each group were analyzed at intervals ot 1,2,4,6 and 8 weeks after neurolysis. Each muscles were examined grossly and histologically after hematoxylin and eosin staining. Experimental studies showed that a peripheral nerve is a well vascularized structure with a considerable reserve capacity in its microirculation. The intrinsic collateral system is well developeed and experimental deta supported the view that peripheral nerves may be mobilized over a cons derable length with or the only minium interference with their microvascular flow. The results were as follows: 1. The first evidence of histologic change in the muscle fibers was in the sarcolemmal neclei. 2. Localized atrophy of muscle fibers were observed at the six weeks after neurolysis. 3. With increasing length of neurolysis, abnormal finding were developed in early stage. 4. Massive atrophy of muscle fibers were noted in the muscle fibers which neurolysed more 7cm.
Animals, Laboratory ; Atrophy ; DEET ; Eosine Yellowish-(YS) ; Hematoxylin ; Muscles ; Peripheral Nerves ; Sciatic Nerve ; Surgeons ; Urethane ; Vasa Nervorum

No abstract available.
HL-60 Cells* ; Humans ; Mass Screening* ; Protein Kinases*

We describe a case of cutaneous angiomyolipoma found in the ear lobe, that is not associated with tuberous sclerosis. The lesion developed on the youngest patient yet reported in the literature.
Angiomyolipoma* ; Ear ; Humans ; Tuberous Sclerosis

No abstract available.
Lung* ; Pneumonia*

To evaluate the efficacy of anthelmintic treatment of Enterobius vermicularis in highly endemic population, total 82 children in two orphanage institutes were divided into 4 groups and treated with placebo, 5 mg/kg of pyrvinium pamoate, 100 mg of mebendazole and 10 mg/kg of pyrantel pamoate respectively. Total 4 anal swabs were taken from each child before treatment and the even distributions of positive rate and consecutive results between groups were considered. Follow-up swabs were taken 8 times up to the 40th day after treatment. After remarkable and significant reduction of positive rates up to 19-27th day after treatment in respective groups, the remarkable egg positive conversions were observed 3-4 weeks after treatment. The positive conversion was the earliest and the most remarkable in pyrantel-treated children and the slowest and the least remarkable in mebendazole-treated cases. Also found was that the figures of negative conversion were different with statistical significance between two categories of cases, consecutively positive and alternately positive cases of pre-treatment swabs. This means that the conventional indices of cure rate in E. vermicularis infection may be variable by the selection of subjected cases. Above results mean that the spectrum of susceptible pinworms according to the developmental stages are different between currently available drugs, and the ability to remove pinworms completely in certain developmental stage are also different between chemotherapeutics. These results suggest the need of interval chemotherapy of Enterobius vermicularis infection in heavily infected cases of in highly endemic population to achieve the complete eradication of whole range of pinworms in intestine.
parasitology-helminth-nematoda ; Enterobius vermicularis ; chemotherapy- mebendazole ; pyrantel pamoate ; enterobiasis

No abstract available.
Astrocytoma* ; Tuberous Sclerosis*

The Hongcheon river system flows down through the Hongcheon area of Kangwon-do, and reaches to the Cheongpyeong Dam in Kyonggi-do. Stool specimens from the inhabitants residing along the Hongcheon river basin were examined to detect infection rate of Metagonimus sp., and the intermediate hosts were collected to detect larval stages. The results obtained were as follows: Thirty-nine (33 males and 6 females) out of 529 (314 males and 215 females) inhabitants were infected with Metagonimus sp., showing a total positive rate of 7.4 per cent. In eight areas surveyed, the specimens from Kulji-ri of Bukbang-myon at the middle part of the river showed the highest positive rate of 26.9 per cent (14 positives out of 52) (males; 38.2per cent). The specimens from Mogog-ri of Seo-myon at the downstream of the river showed a positive rate of 10.4 per cent (13 positives out of 125) (males;12.6 per cent). The positive rates in other regions were less than 10 per cent. The density of the first intermediate host, Semisulcospira sp., was the highest in Kulji-ri of Bukbang-myon (10-20 snails per m(2)), and the infection rate of Metagonimus cercariae in the snails was 10.7 per cent(13 positives out of 121 snails). The infection rate of Metagonimus metacercariae in Zacco platypus, the fresh water fish favorably eaten raw by the inhabitants, was 68.2 per cent (30 positives out of 44 fishes), and most metacercariae were detected under the scales (89.9 per cent). Adult flukes were obtained from the small intestine of a rat, 15 days after infection with the metacercariae obtained from Z. platypus. These adult flukes were identified to be the same srecies as those obtained from human hosts. By this survey, new endemic areas of Metagonimus infection were discovered along the Hongcheon river basin and the main source of infection was the fresh water fish, Z. platypus.
parasitology-helminth-termatoda ; Metagonimus sp. ; epidemiology ; metacercaria ; Zacco platypus

No abstract available.
Leukoencephalopathies*

Conjunctival tuberculosis is a very rare disease in thesedays. Koester first reported a case of tuberculosis of the conjunctiva in 1873. Two cases of tuberculosis of the conjunctiva has been reported in korea. We experienced a 54-years-old female patient with subconjunctival nodule which was freely movable in temporal bulbar conjunctiva and covering conjunctiva was hyperemic. We performed excisional biopsy and Ziehl-Neelsen stain revealed many acid-fast bacili. No evidence of systemic tuberculosis was found. We diagnosed as primary conjunctival tuberculosis. This case was unusual in that no palpable lymphadenopathy and old age. We should differentially diagnose conjunctival tuberculosis from other disease presenting clinical findings, and pathologic findings will be presented and literatures will be reviewed.
Biopsy ; Conjunctiva ; Female ; Humans ; Korea ; Lymphatic Diseases ; Rare Diseases ; Tuberculosis*

Conjunctival tuberculosis is a very rare disease in thesedays. Koester first reported a case of tuberculosis of the conjunctiva in 1873. Two cases of tuberculosis of the conjunctiva has been reported in korea. We experienced a 54-years-old female patient with subconjunctival nodule which was freely movable in temporal bulbar conjunctiva and covering conjunctiva was hyperemic. We performed excisional biopsy and Ziehl-Neelsen stain revealed many acid-fast bacili. No evidence of systemic tuberculosis was found. We diagnosed as primary conjunctival tuberculosis. This case was unusual in that no palpable lymphadenopathy and old age. We should differentially diagnose conjunctival tuberculosis from other disease presenting clinical findings, and pathologic findings will be presented and literatures will be reviewed.
Biopsy ; Conjunctiva ; Female ; Humans ; Korea ; Lymphatic Diseases ; Rare Diseases ; Tuberculosis*