No abstract available.
Extracorporeal Circulation* ; Heparin*

To understand the mode of transmission in clonorchiasis, a survey was made in Kim-hae Goon, South Kyong-sang Do (=Province). The mathematical analysis of the age prevalence was done on the egg positive rates. And another analysis for the comparison was also made to the cited data from two areas, North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do. Some catalytic models of H. Muench (1959) were applied to the observed age prevalence. Because the both parameters, such as force of infection(a) and loss of positivity(b) were considered to be constant for a long period in the surveyed area, the two stage catalytic model by Muench was chosen to the analysis. In the surveyed area, Kim-hae Goon where the egg positive rates were 56.2 percent and 61.2 percent (by Kim, 1974), the constant values of 'a' were found to be 0.051 and 0.089 respectively. In other words, the force of infection was 51, 89 per 1,000 susceptibles. The values of 'b' were found to be 0.006 and 0.005. This means that the rates of disappearance from egg positive cases to negative were 6 and 5 per annum per l,000 positive cases in above area. Therefore, the two catalytic curves were expressed by the following equations, y = 1.133 {e(-0.006t) - e(-0.051t)} and y = 1.047 {e(-0.005t) - e(-0.089t)} respectively. In the cases of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do where the egg positive rates of clonorchis shown as 27.7 percent and 15.2 percent by Shin (1964) and Kim (l974), the curves were expressed by y = 1.769 {e(-0.010t) - e(-0.034t)} and y = 2.857 {e(-0.020t) - e(-0.027t)} respectively. From the above mathematical analyses by age prevalence in clonorchiasis, it was considered that the mode of transmission of clonorchiasis in the surveyed area, Kim-hae Goon presented more rapid pattern than those of North Kyong-sang Do and Ko-yang Goon, Kyong-gi Do.
parasitology-helminth-trematoda ; clonorchiasis-Clnorchis sinensis ; epidemiology ; transmission

The nonstructural protein NSP4, encoded by gene 10 of rotavirus, has been shown to play a role in viral assembly and known to be an enterotoxin, causing diarrhea in mouse pups. NSP4 gene was cloned from CBNU-2 (virulent bovine rotavirus/diarrheic fecal sample) and CBNU-1 (cell-culture adapted bovine rotavirus/isolated from CBNU-2 and 75 times passaged on MA104 cells), respectively, by reverse transcriptase-polymerase chain reaction (RT-PCR) and sequenced and compared. The sequence data indicated that the NSP4 genes of bovine rotavirus (BRV) were 751 bases in length and encoded one open reading frame of 175 amino acids beginning at base 42 and terminating at base 570. Differences in nucleotide sequence between CBNU-2 and CBNU-1 were observed at 6 positions (base 274, 296, 391, 394, 396 and 579). NSP4 gene of BRV exhibited a high degree of nucleotide (90% and 94%) and amino acid sequence (91% and 94%) and amino acid sequence (91% and 97%) homology with those of SA11 and UK but a low degree of nucleotide (77% and 79%) and amino acids sequence (81% and 85%) homology with those of Wa and OSU.
Amino Acid Sequence ; Amino Acids ; Animals ; Base Sequence ; Clone Cells* ; Cloning, Organism* ; Diarrhea ; Enterotoxins ; Korea* ; Mice ; Open Reading Frames ; Rotavirus* ; Virus Assembly

PURPOSE: Endothelin-1(ET-1) is a potent vasoconstrictor peptide. It has potent contractile and proliferative effects on vascular smooth muscle cells. Congenital heart diseases are often accompanied by pulmonary hypertension, and the severity of pulmonary hypertension is important in the prognosis. The aim of this study was to elucidate changes of ET-1 after pulmonary venous stenosis in a dog model, and investigate the interaction between pulmonary venous pressure and ET-1. METHODS: Plasma ET-1 levels were measured by radioimmuno-assay at the thoracic aorta, left pulmonary artery and left pulmonary vein. Pressures were also monitored at the same sites. Immunohistochemical staining of ET-1 was performed in the lung tissue. RESULTS: Increased serum ET-1 levels were noted at 1 hour after left pulmonary vein stenosis in the left pulmonary vein and aorta, and at 2 days after stenosis in the left pulmonary artery. Left pulmonary venous pressure was significantly increased at 1 hour after pulmonary vein stenosis, and systolic pulmonary artery pressure at 2 days after stenosis. Increased expression of ET-1 was noted by immunohistochemical staining at the lung tissue at 7 days after stenosis of left pulmonary vein. CONCLUSION: Increased serum ET-1 level and expression of ET-1 in immunohistochemical staining at lung tissue were noted after stenosis of pulmonary vein. Serum ET-1 level would be useful in the diagnosis and prediction of pulmonary artery hypertension. (J Korean Pediatr Soc 2000;43:769 778)
Animals ; Aorta ; Aorta, Thoracic ; Constriction, Pathologic* ; Diagnosis ; Dogs ; Endothelin-1* ; Endothelins ; Heart Diseases ; Hypertension ; Hypertension, Pulmonary ; Lung ; Muscle, Smooth, Vascular ; Plasma ; Prognosis ; Pulmonary Artery ; Pulmonary Veins ; Venous Pressure

No abstract available.
Tachycardia*

Diabetes mellitus, obstructive uropathy and urinary infection were considered to be most important in the etiology of renal papillary necrosis in the past literature. However, since 1953, Spuhler and Zollinger reported an association between phenacetin abuse and renal papillary necrosis, the most frequent cause of renal papillary necrosis has been diabetes mellitus, while analgesic abuse (contained phenacetin) has been the second most common factor in recent reports. In the more recent literature, most of the patient have had neither obstructive uropathy nor urinary infection, and it is quite possible that there two condition are of no direct etiological significance. But in this case, we can not suggest definite etiological factor except urinary infection clinically. Only one case is reported showing clinical manifestations laboratory findings, pyelographic findings and pathological changes compare with previous papers.
Diabetes Mellitus ; Humans ; Necrosis* ; Phenacetin

No abstract available.
Meningitis, Meningococcal* ; Pericarditis*

Osteochondritis dissecans occurs most commonly in knee joint and often in elbow, ankle, shoulder, hip than in other joint. In osteochondiritis dissecans, an area of subchondral bone undergoes avascular necrosis and degenerative change ususlly occurs in cartilage overlying it. During the course of disease, unless interrupted by treatment or spontaneous healing, the necrotic bone and cartilage seperates from adjacent bone and cartilage and together becomes loose body. To promote healing, the proper treatment is necessary before degenerative change developes. The authors reviewed 11 cases of osteochondritis dissecans which recieved treatment at Severance hospital from January 1972 to December 1981. The results were obtained as follows: 1. The incidence of osteochondritis dissecans in male was a little more frequent than that of female and 50% were observed in the age of 16 to 30 years. 2. The most common symptom and sign was pain and limitation of motion, instability senastion, tenderness, snapping sound in order of frequency. 3. The most common area involved was the knee in 9 cases, 5 cases involved the medial femoral condyle, 4 cases involved the lateral femoral condyle. The ankle and elbow was 1 case for each. 4. Eight(72.7%) of 11 cases had history of trauma. 5. Among 9 cases of knee inlovement, 5 (55.6%) cases were associated with rupture of meniscus. 6. The methods of treatment were as follows. Conservative..................................................................1 Operative Curettage and drilling........................................................6 Excision......................................................................3 Curettage and bone graft.......................................................1 Internal fixation..............................................................1 7. Conservative treatment was performed in one case, but failed. So, all 11 cases recieved operative treatment and obtained satisfactory results in 72.8%.
Ankle ; Cartilage ; Curettage ; Elbow ; Female ; Hip ; Humans ; Incidence ; Joints ; Knee ; Knee Joint ; Male ; Necrosis ; Osteochondritis Dissecans ; Osteochondritis ; Rupture ; Shoulder

No abstract available.
Humans ; Infant, Newborn* ; Respiration, Artificial ; Survival Rate ; Ventilators, Mechanical*

Two cases of Kartageneranjx syndrome were presented. They were sisters in the same family and were 15 years and 13 years old respectively. Chief complaints of the first case were chronic cough and expectoration and of the second case were chronic cough, expectoration and nasal stuffiness. Situs inversus, bronchiectasis and paranasal sinusitis were identified in both cases. EKG showed typical findings of mirror image compatible with dextrocardia in all two cases. Administration of antibiotics and postural drainage were performed with good resultin the first case but no remarkable improvement in the second case. A brief review of literatures was made.
Adolescent ; Anti-Bacterial Agents ; Bronchiectasis ; Cough ; Dextrocardia ; Drainage, Postural ; Electrocardiography ; Humans ; Siblings* ; Sinusitis ; Situs Inversus