No abstract available.
eIF-2 Kinase* ; HIV-1* ; Phosphorylation

The bipolar hemiarthroplasty is one of the treatment methods of the avascular necrosis of the femoral head and the fracture of the femur neck. The mechanism of bipolar hemiarthroplasty is intended to distribute the forces at the site of the inner and outer articulation, and theoritically diminish acetabular wear and produce a painless arthroplasty. The authors analyzed motion of two components in 23 cases of the bipolar hemiarthroplasty, performed at the Department of Orthopaedic Surgery, Korea University Hospital, between January, 1985 and January, 1993 with average 47 months follow up(range 24 to 84 months). The results obtained were as follows: 1. In the motion of the two components, inner bearing motion was average 11.5 degrees(from 1 to 29 degrees) and outer bearing motion was average 21.4 degrees(from 3 to 45 degrees). 2. The inner bearing motion was highest at 12 months with average 16 degrees and outer bearing motion was lowest during the same period with average 15 degrees. During the follow up the inner bearing motion was decreased whereas outer bearing motion was increased. 3. The inner or outer bearing motion of bipolar component was no correlation with age, sex and clinical result.
Acetabulum ; Arthroplasty ; Femur Neck ; Follow-Up Studies ; Head ; Hemiarthroplasty ; Korea ; Necrosis

Although there are various methods of operative treatment for hony mallet finger, the operative technique is not so easy and complications such as joint stiffness, sott tissue prohlems, infection, change of nail shape and arthrosis are common. The authors performed operations for 26 cases of hony mallet fingers, fixing the hony frapment by Kirschner wire, pull-out wire suture and miniscrew respectively, from Jan. l988 to Jun. l996. The results were as follows. l. According to Niechajev's classification. there were 3 cases of type B, 7 cases of type C, l4 cases of type D, and 2 cases of type E. And 11 cases were accompanied hy crushing injury. 2. Involved fingers were third finger in 11cases, fit'th finger in 7 cases, fourth finger in 5 cases, second finger in 2 cases. and thumb in I case. 3. The hony mallet finger was caused hy occupational injury in l6 cases, direct blow in 7 cases and sports injury in 3 cases. 4. The fractured fragment was fixed hy Kirschner wire in 9 cases, by pull-out suture in 9 cases and by miniscrew in 8 cases. 5. The results were evaluated hy Kanies scale. Sixteen cases had satisfactory results. Seven cases (87.5%) were satisfactory in miniscrew fixations. 5 cascs (55.6%) in pull-out wire suture methocls and 2 cases (22.2%) in Kirschner wire tixations. 6. The complications were joint incongruity in 4 cases, dorsal prominece in 6 cases, painful limitation of motion in 2 cases which were treated by arthrodesis, pin site infection in 2 cases and hreakage of wire suture in 1 case. 7. The miniscrew fixation offered relatively firm fixation, low complication rate, and good results. so it can be considered as one of the good methods of treatment for hony mallet finger.
Arthrodesis ; Athletic Injuries ; Classification ; Fingers* ; Joints ; Occupational Injuries ; Sutures ; Thumb

Congenital origin intestinal obstruction are important disease due to required emergency operation. So accurate and rapid diagnosis needed for decreased mortality and morbidity. Radiologic must defect to accurate obstruction site and also associated other congenital anomalies. And also embryological basis are very important role to the diagnosis of these diseases. We were analyzed radiologically and clinically 25 cases with congenital origin intestinal obstruction with review of literature. 1. Hypertrophic pyloric stenosis 6 cases, midgut malrotation 4 cases, congenital megacolon 8 cases, imperforated anus 5 cases, ileal atresia 1 case and duodenal atresia 1 case. 2. Male and female radio was 16:9. Especially on hypertrophic pyloric stenosis, 5 cases were male infants. 3. All cases of hypertrophic pyloric stenosis represented string sign and also pyloric beak sign, shoulder sign on UGI. 4. 1 case duodenal atresia showed double bubble sign on simple abdomen x-ray and ileal atresia showed mechanical small bowel obstruction sign with microcolon. 5. On midgut malrotaton, cecum was located in right upper abdomen on 4 cases. And 2 cases were associated with Ladd's band, 1 case with volvulus and 1 case with mesenteric defect. 6. Involved site of all congenital megacolon were localized to rectosigmoid colon. 7. On 5 cases imperforated anus, 3 cases were low type and 2 case high type. Rectoperitoneal and rectourogenital fistula were demonstrated on 4 cases.
Abdomen ; Anal Canal ; Animals ; Beak ; Cecum ; Colon ; Diagnosis ; Emergencies ; Female ; Fistula ; Hirschsprung Disease ; Humans ; Infant ; Infant, Newborn* ; Intestinal Obstruction* ; Intestinal Volvulus ; Male ; Mortality ; Pyloric Stenosis, Hypertrophic ; Shoulder

No abstract available.
Diagnosis*

No abstract available.
Foot* ; Free Tissue Flaps*

No abstract available.

No abstract available.
Extremities* ; Osteogenesis* ; Ultrasonography*

No abstract available in English.

Prostate cancer is one of the most frequent cancers in Western countries and has been also one of the most rapidly increasing malignant diseases in Korean men. This disease shows diverse features in clinical course ranging from an indolent disease to a lethal one. Accordingly, underlying molecular mechanisms and genetic changes involved in the development and progression of various types of prostate cancer are very heterogeneous. Thus, investigation of pathogenesis of prostate cancer is very challenging, and, at this point of time, only a handful of molecular and genetic factors were identified as pathogenic factors for prostate cancer. Plenty of data support the strong relationship between age, race and family history and the development of prostate cancer. In addition, androgen related factors such as androgen metabolism and receptor signaling are highly correlated with tumor development and progression. Numerous genetic or epigenetic changes including gene mutation and methylation contribute to the development and progression of prostate cancer. In this article, we summarize the current understanding of the pathogenesis of prostate cancer, with a special focus on underlying genetic and epigenetic alterations.
Continental Population Groups ; Epigenomics ; Hand ; Humans ; Male ; Methylation ; Prostate ; Prostatic Neoplasms