No abstract available.
Tumor Lysis Syndrome*

No abstract available.

Eruptive neonatal hemangiomatosis is an uncommon disorder, which is divided into two types according to the extent of involvement: Benign type with cutaneous hemangiomatosis only and diffuse type with widespread hemangiomas of skin and viscera. The organs commonly affected are the gastrointestinal tract, brain, liver and lung. The Diffuse type is often fatal. We herein report a case of eruptive neonatal hemangtomatosis with cutaneous and hepatic involvement. The size of the hepatic arteriovenous malformation was markedly decreased after 2 months' therapy with oral prednisolone.
Arteriovenous Malformations ; Brain ; Gastrointestinal Tract ; Hemangioma ; Liver ; Lung ; Prednisolone ; Skin ; Viscera

We report a case of hypertrophic lupus vulgaris in the right knee of an 18-year-old man. The lesion, an erythematous scaly hypertrophic plaque, had grown for 12 years without any trestment leaving an atrophic scar. Histopathologically, the lesion consisted of s granuloma composed of epithelioid cells and lymphocytes. Lsboratory examinations including hematology, blood chemistry, urinalysis, and chest roentgenography were normal. The Mantoux test was strongly positive. Treatment with anti-tuberculosis medieation resulted in a good response.
Adolescent ; Chemistry ; Cicatrix ; Epithelioid Cells ; Granuloma ; Hematology ; Humans ; Knee ; Lupus Vulgaris* ; Lymphocytes ; Radiography ; Thorax ; Urinalysis

No abstract available.
External Fixators* ; Foot Deformities* ; Foot*

The epidemiology of children with cortical visual impairment(CVI)has been poorly defined till now, so the purposes of this study were to define the visual prognosis and prevalence of ophthalmologic problems in Korean children. The 20 children with follow-up of over 3 months were included out of 24 children diagnosed with CVI. The causes of CVI were periventricular leukomalacia in 7, congenital malformation in 4, and cerebral infarct or atrophy. Twelve of 19 children who had visual impairment at their initial visit showed visual improvement with follow-up. There were strabismus in 14, nystagmus in 6, and abnormal optic disc in 8 of the 20 children. All visualevoked response results were abnormal, but were not providing a more reliable prognosis in vision. The children who had abnormal electroencephalogram had poor visual prognosis as well as delayed developmental level. In conclusion, this study identified that children with CVI may be presented with a variety of ocular abnormalities, including strabismus, nystagmus, and abnormal optic disc. These findings suggest that a better understanding of the natural course will be required in children with CVI.
Atrophy ; Child* ; Electroencephalography ; Epidemiology ; Follow-Up Studies ; Humans ; Infant, Newborn ; Leukomalacia, Periventricular ; Magnetic Resonance Imaging ; Prevalence ; Prognosis ; Strabismus ; Vision Disorders*

No abstract available.
Child* ; Heart Neoplasms* ; Humans

The presence of a lupus anticoagulant was evaluated in patients with Bechet's disease by the kaolin clotting time method. Four percents (three patients) of 69 patients analyzed were found positive for the lupus anticoagulant. However, no statistically significant association existed between the presence of this antibody and the presence of thrombosis, clinical activity, clinical type, antinuclear antibodies and the positive VDRL test.
Behcet Syndrome/*immunology ; Cardiolipins/immunology ; Female ; Human ; Lupus Coagulation Inhibitor/*analysis ; Male

No abstract available.
Burkitt Lymphoma* ; Tumor Lysis Syndrome*

BACKGROUND: Although insulin induced hypoglycemia test is a standard diagnostic method in assessment of hypothalamo-pituitary-adrenal axis, rapid ACTH stimulation test using 250microgram has been used as a first line diagnostic test especially in secondary adrenal insufficiency due to iatrogenic Cushing syndrome because it is easy and safe. However, it was suggested that a maximal cortisol response can be achieved with a much lower ACTH dose and 1microgram ACTH enhances the sensitivity without decreasing specificity of test. Also recently, there was a report that midnight to morning urine cortisol increment is more accurate, noninvasive method can be used for measurement of hypothalmo-pituitary-adrenal axis. In this study, we compared the 1microgram ACTH stimulation test with midnight to morning urinary free cortisol increment in secondary adrenal insufficiency due to iatrogenic Cushing syndrome to study the agreement of two test and accuracy of increment of urinary free cortisol in diagnosis of adrenal insufficiency. METHODS: Double voided urine sample were collected at midnight and 8 A.M. in 12 patients who have Cushing-like feature and history of taking glucocorticoids and in 12 normal controls. Urinary free cortisol was measured and cortisol increment was defined as the morning urine free cortisol minus the midnight urine free cortisol. The 1microgram ACTH stimulation test was performed in 12 iatrogenic Cushing syndrome patients at the same day and compard with the result of cortisol increment. RESULTS: Using the results of 12 controls, normal urine free cortisol increment was defined as greater than 165.5nmol/L(6.0microgram/dL). Subnormal cortisol response in 1microgram ACTH stimulation test was noted in 8 out of 12 patients group and urinary free cortisol increment was not observed in 7 out of 8 subnormal response group. Normal cortisol response in 1microgram ACTH stimulation test was noted in 4 out of 12 patients group and urinary free cortisol increment was observed in 3 out of 4 normal response group. So 83% of concordance rate between 1microgram ACTH stimulation test and urine free cortisol increment was recorded. CONCLUSION: Urinary free cortisol increment has high concordance rate with 1microgram ACTH stimulation test and simple, easy test in diagnosing secondary adrenal insufficiency due to iatrogenic Cushing syndrome. Further study including more patients will be helpful to know the adequacy and reliability of test in evaluation of hypothalamo-pituitary-adrenal axis.
Adrenal Insufficiency ; Adrenocorticotropic Hormone ; Axis, Cervical Vertebra ; Cushing Syndrome* ; Diagnosis* ; Diagnostic Tests, Routine ; Glucocorticoids ; Humans ; Hydrocortisone* ; Hypoglycemia ; Insulin ; Sensitivity and Specificity