OBJECTIVE:To study the preparation and quality control methods of ribavirin and ephedrine nasal spray and observe its clinical therapeutic efficacy.METHODS:To determine the content of ribavirin and that of ephedrine hydrochloride by ultraviolet spectrophotometry and polarimetry respectively and observe the clinical therapeutic efficacy in 40 patients.RES_ULTS:The average recoveries of ribavirin and ephedrine hydrochloride were 100.05%(RSD=0.50%) and 100.10%(RSD=0.29%) respectively.Its effective rate in treating virus infections of upper respiratory tract was 97%.CONCLUSION:The preparation of ribavirin and ephedrine nasal sprays is reasonable in technology,stable in quality,feasible in quality control and reliable in therapeutic efficacy.It is worth popularizing the application of this preparation.

This article analysis the present situation of less than 35 years of Sun Yat-sen university youth scientific and technological personnel,they declare、undertake to support basic research based science fundation related cases,discusses the science foundation for their assistance and training problems,put forward youth scientific talents to suit the science funds development requirements to promote their development proposals

Objective To evaluate the value of MSCT three-dimensional reconstruction postprocessing technique for operation of Scoliosis Orthomorphia. Methods 18 cases of scoliosis were performed with MSCT to be reconstructed by MPR, VRT. The three-dimensional reconstruction images displayed traverse, coronal and sagittal plane and measures data. Results By measuring data of 18 cases by means of the methods above, all parameters were accurate. Conclusion The three-dimensional reconstruction of MSCT makes up the disadvantages of X-ray. Any retrospective reconstruction can be done to the collected data. So patients can avoid being projected repeatedly and radiation can be reduced. Various parameters of the vertebrae concerning spine, spinal canal and the pedicle plane can be offered, providing reliable reference for pre-operations.

Objective To measure the volume of liver, the volume of mass of liver and the ratio of mass/righe lobe with the Volume Evaluation of MSCT, as a reference of liver function after resection of liver mass. Methods All cases were scanned and reconstructed with MSCT,and the volume of right liver, the volume of mass of right liver and its ratio were obtained with Volume Evaluation of MSCT. Results The method of measuring volume of liver with Volume Evaluation is simple and accurate. Conclusion It can be a important reference before and after resection of liver mass.

Endometrial Neoplasms ; pathology ; surgery ; Female ; Humans ; Lymph Node Excision ; methods ; Lymph Nodes ; pathology ; Neoplasm Staging ; Ovarian Neoplasms ; pathology ; surgery ; Retroperitoneal Space

0.05).Conclusion The intervertebral fusion cage of n-HA/PA66 has good biocompatibility and osteo-conductibility.It may be the ideal interbody fusion cage.

Objective To detect the serum proteomic patterns using SELDI-TOF-MS ProteinChip array technology in gastric cancer,screen biomarker candidates,build diagnostic models and evaluate its clinical significance in early gastric cancer.Methods SELDI-TOF-MS ProteinChip was used to detect the serum proteomic patterns of 40 patients with gastric cancer and 30 healthy people.The diagnostic models were developed and validated by discriminant analysis.Results The model composed by 3 protein peaks 8592m/z、13725m/z and 8678m/z could do the best in the diagnosis of gastric cancer.The specificity and sensitivity of it were 86.5%(26/30)and 90%(36/40)respectively.Conclusions This method show great potential for the early detection,staging before operation and screening novel and better biomarkers to early gastric cancer.

OBJECTIVE To explore whether auditory event-related potential (AERP)exists in rat and what its features are,and to set up a set of AERP recording technique. METHODS Ten normal juvenile and 10 adult rats were served as subjects. Each rat was anesthetized and recorded AERP with passive mode. The responsibility of AERPs between juvenile and adult rats was compared. Also,the responsibility of AERP between rats and normal humans was compared. RESULTS AERPs could be evoked with passive recording mode in rats. Although the latencies and amplitudes of juvenile rats were respectively shorter and lower than thoses of adult rats,there were no significance in statistics. The AERP waveform of rats was similar to that of humans essentially. However,compared to the humans,the responsibility and stability of AERP in rats were less satisfied. CONCLUSION A similar AERP exists in rat and human. AERP has a process of development,differentiation and maturation,which may accomplish in early age in rat. Rat can serve as the candidate animal for AERP research.

Potassium channels which are targets of antiarrhythmic drugs (class III) play an important role in cardiomyocyte membrane. Recently, with the application of molecular biology techniques , development of cloned potassium channels, successful isolation of human cardiomyocytes and research of single channel, scientists have learnedmore characteristics of kinetics, electrophysiology and pharmacology of potassium channels. All these help them to develop and study new antiarrhythmic drugs.

Probiotics modulate the biological functions (and even cell apoptosis) of intestinal epithelial cells,intestinal macrophages,intestinal dendritic cells,and T cells via cell signaling pathways including nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) pathways.Peroxisome proliferator-activated receptor γ (PPARγ) and heat shock protein (hsp) are targets for probiotics or their products.