1.Congenital Hemihypertrophy (Congenital Total Segmental Hypertrophy)
The Journal of the Korean Orthopaedic Association 1970;5(3):103-106
Congenital hemihypertrophy is one of the more unusual and interesting errors of nature found in the human race. The hemihypertrophy was first described by Meckel in 1822, and the first case was recorded by Wagner in 1839. Since that time, over 140 cases have been reported. The purpose of this article is to report an additional case along with review of previous literatures.
Continental Population Groups
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Humans
4.A Report of the 54th Annual Scientifice Meeting of AMDA.
Korean Journal of Aerospace and Environmental Medicine 1999;9(2):167-170
No abstract available.
5.Late Metabolic Consequences of Small for Gestational Age: Insulin Resistance in Children Born SGA.
Journal of Korean Society of Pediatric Endocrinology 2004;9(2):132-135
No abstract available.
Child*
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Gestational Age*
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Humans
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Insulin Resistance*
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Insulin*
6.Production and Characterization of Monoclonal Antibodies to a 75-kDa Major Outer Membrane Protein of Porphyromonas gingivalis.
Journal of the Korean Society for Microbiology 1997;32(6):633-644
Porphyromonas gingivalis has been implicated in adult periodontitis. A 75-kDa major outer membrane protein of P. gingivalis is an immunodominant antigen and is often associated with fimbrial proteins during its purification. The present study was performed to generate monoclonal antibodies (MAbs) to the 75-kDa protein and characterize the protein and the MAbs. Kight-week-old BALB/c mice were immunized with the partially purified 75-kDa protein from P. gingivalis 2561. Spleen cells of the mice were hybridized with SP2/0 Ag-14 mouse myeloma cells and then fused with polyethylene glyeol 3400. Hybrid cells surviving hypoxanthine/aminopterin/thymidine medium were tested for antibody secretion by ELISA. Positive clones were subcloned by limiting dilution and then three subclones were obtained. The subclones were injected peritoneally into Pristane-primed mice to produce MAbs. Immunoreactivity of the MAbs was confirmed by an immunoblot analysis. In the immunoblot using a partially denatured crude 75-kDa protein preparation as an antigen, the 75-kDa protein reacting with the MAbs revealed a ladder- like pattern which has been known as a characteristic of a native polymeric form of fimbriae. The intervals of the ladders, however, were different from those of fimbrial protein. The MAbs also recognized the completely denatured 75-kDa protein. Immunogold localization using IgG fraction of the MAbs demonstrated that the gold particles were deposited on globules on the surface of P. gingivalis 2561, but not on fimbriae. These results suggest that the 75-kDa protein is antigenically different from fimbrial protein and in nature, is not associated with, but may be physicochemically associated with the fimbrial protein during extraction and purification procedures for these proteins. Immunoreactivity of these 3 MAbs was tested by immunoblot using sonic extracts from various P. gingivalis strains. All the MAbs reacted only with the strains having proteins in their sonic extracts with a molecular mass of 75 kDa, but failed to recognize the strains having proteins with molecular masses of 61, 61.5, 76, and 78 kDa. These results indicate that strains of P. gingivalis have antigenically different major outer membrane proteins and the MAbs in the present study might have been raised against the same common, exposed immunodominant epitope in the 75-kDa proteins.
Animals
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Antibodies, Monoclonal*
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Chronic Periodontitis
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Clone Cells
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Enzyme-Linked Immunosorbent Assay
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Hybrid Cells
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Immunoglobulin G
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Membrane Proteins*
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Membranes*
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Mice
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Polyethylene
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Polymers
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Porphyromonas gingivalis*
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Porphyromonas*
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Spleen
7.THE STUDY ON THE ADMINISTRATION PERIOD OF POSTOPERATIVE PROPHYLACTIC ANTIBIOTICS AND ANTI-INFLAMMATORY DRUGS USED TO REDUCE EDEMA..
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):612-619
The purpose of this study was to evaluate the administration period of the prophylactic antibiotic and anti-inflammatory drug used to reduce postoperative infection and edema, as compared with normal tissue healing period after operation. Author selected the 98 patients who had been performed maxillofacial bone fracture surgery, orthognathic surgery, sort tissue surgery, removal of miniplate and screw, and cyst operation, among 159 patients admitted to the department of oral and maxillofacial surgery of the one general hospital in Daegu city, during 6 months from January to June 1996. The results was slightly long administration for antibiotics and anti-inflammatory agents, as compared with physiologic healing process after surgery. Conclusively, the author propose that prophylactic antibiotics administration should be limited within 3 to 7 days after operation, and 3 to 5 days for anti-inflammatory drugs.
Anti-Bacterial Agents*
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Anti-Inflammatory Agents
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Daegu
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Edema*
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Fractures, Bone
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Hospitals, General
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Humans
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Orthognathic Surgery
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Surgery, Oral
8.Relation of psychosocial stress, eye strain, and critical flicker fusion of VDT workers.
Korean Journal of Aerospace and Environmental Medicine 2001;11(1):32-35
To clarify that the psychosocial factors affect the eye strain of the VDT workers, self-reporting questionnaire about eye strain, critical flicker fusion(CFF), and 12-item version of General Health Questionnaire(GHQ) were carried out to 13 female VDT workers who have done the electronic editing and 10 female controls who were nurses in one hospital. The sum of eye symptoms of VDT workers were significantly higher than controls, but CFF of both groups were not different. And the sum of eye symptoms and CFF were not correlated. High stress group(sum of GHQ > 3) shows significantly more eye symptoms than low stress group. This result suggest that the psychosocial factors could affect the eye strain of VDT workers.
Asthenopia
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Female
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Flicker Fusion*
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Humans
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Psychology
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Word Processing
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Surveys and Questionnaires
9.DNAse I hypersensitive sites of lung specific transcription factor gene.
Tuberculosis and Respiratory Diseases 2000;48(6):879-886
BACKGROUND: Thyroid Transcription Factor-1(TTF-1) acts as a tissue specific transcription factor in the regulation of lung specific gene expression and as morphogenic protein during lung organogenesis. Currently, there is very little information on the cis-acting sequences and transcription and transcription factors that direct the TTF-1 gene expression. DNAse 1 hypersensitive (DH) sites represent a marker for active or potentially active chromatin and are likely to be especially important in gene regulation, being associated with many DNA sequences that regulate gene expression. It is clear that DH regions correlate with genetic regulatory loci and binding for sequence-specific DNA-binding proteins. METHODS: We have used DH site assays to identify putative distal regulatory elements in H441 lung adenocarcinoma cells, which express the TTF-1 gene and HeLa cells. RESULTS: There are four DH sites 5' of the TTF-1 gene. These sites are located at base pair approximately +150, -450, -800, and -1500 from the start of transcription. CONCLUSION: These data suggest that there may be at least one intragenic site and regulatory region 5' prime to the promotor region.
Adenocarcinoma
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Base Pairing
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Base Sequence
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Chromatin
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Deoxyribonuclease I*
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Deoxyribonucleases*
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DNA-Binding Proteins
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Gene Expression
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HeLa Cells
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Humans
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Lung*
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Organogenesis
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Promoter Regions, Genetic
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Regulatory Sequences, Nucleic Acid
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Thyroid Gland
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Transcription Factors*
10.A Report of the 47th International Congress of Aviation and Space Medicine in Budapest, Hungary.
Korean Journal of Aerospace and Environmental Medicine 1999;9(3):288-290
No abstract available.
Aerospace Medicine*
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Aviation*
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Hungary*