No abstract available.
Animals ; Mice* ; Oocytes*

Present trial was carried out to evaluate the anthelmintic efficacy of oxantel/pyrantel tablets against intestinal nematode infections, and to determine the efficacy of oxantel tablels against Trichuris infection. A total of 34 subjects with the mixed infections were treated with oxantel/pyrantel tablets (100 mg/tablet each) in a single dose of 15 mg/kg body weight, and another group of 22 Trichuris infected cases received oxantel pamoate tablets (125 mg/tablet) in a single dose of 15 mg/kg. All stool examinations were done before the treatment and 3 weeks after the treatment. The cellophane thick smear (Kato's technique) and Stoll's dilution egg counting method were employed. The results of the trial were summarized as follows: The cure rates (egg negative conversion rates) and egg reduction rates for oxantel/pyrantel tablets were 85.3 percent and 97 percent in trichuriasis, 100 percent each in ascariasis and ancylostomiasis. The oxantel tablet treated group demonstrated a cure rate of 90.9 percent and an egg reduction rate of 96.3 percent in the treatment of Trichuris. There were no detectable objective and subjective side effects in this trial. Both oxantel/pyrantel and oxantel pamoate tablets were readily accepted and well tolerated.
parasitology-helminth-nematoda ; Enterobius vermicularis ; Ancylostoma duodenale ; Trichuris trichiura ; chemotherapy-oxantel/pyrante ; oxantel pamoate

PURPOSE: The aim of this retrospective study is to analyze the relationship between local factors and survival rate of dental implant which had been installed and restored in Seoul Veterans Hospital dental center for past 10 years. And when the relationship is found out, it could be helpful to predict the prognosis of dental implants. MATERIALS AND METHODS: A retrospective study of patients receiving root-shaped screw-type dental implants placed from January 2000 to December 2009 was conducted. 6385 implants were placed in 3755 patients. The following data were collected from the dental records and radiographs: patient's age, gender, implant type and surface, length, diameter, location of implant placement, bone quality, prosthesis type. The correlations between these data and survival rate were analyzed. Statistical analysis was performed with the use of Kaplan-Meier analysis, Chi-square test and odds ratio. RESULTS: In all, 6385 implants were placed in 3755 patients (3120 male, 635 female; mean age 65 +/- 10.58 years). 108 implants failed and the cumulative survival rate was 96.33%. There were significant differences in age, implant type and surface, length, location and prosthesis type (P<.05). No significant differences were found in relation to the following factors: gender, diameter and bone quality (P>.05). CONCLUSION: Related factors such as age, implant type, length, location and prosthesis type had a significant effect on the implant survival.
Dental Implants ; Dental Records ; Hospitals, Veterans ; Humans ; Kaplan-Meier Estimate ; Male ; Prognosis ; Prostheses and Implants ; Retrospective Studies ; Survival Rate

A total of 56 subjects with multiple nematode infections with T. trichiura, Ascaris, hookworms and Enterobius were treated with oxantel and pyrantel pamoate mixture in a paratable suspension(50 mg of each per ml). A single dose of 10 mg per kg body weight in each cured 100 per cent of 54 subjects with Ascaris, 97.1 per cent of 35 subjects with hookworms, 77.8 per cent of 36 with Enterobius and 73.2 per cent of 56 subjects with T. trichiura infestation. The mean egg per gram stool reduction rate in T. trichiura infection was 91.9%. Of the 31 subjects infected with Ancylostoma doudenale 96.8% were cured with a single dose and 4 infected with Necator americanus showed a 100% cure rate with a similar daily dose on 3 consecutive days. Side effects were few and mild. There was no clinical or laboratory evidence of drug toxicity. These findings show a single dose of oxantel and pyrantel pamoate mixture to be a highly effective and acceptable treatment for multiple infections with these nematodes.
parasitology-helminth-nematoda ; Trichuris trichiura ; Ascaris lumbricoides ; hookworm ; Enterobius vermicularis ; chemotherapy-oxantel pamoate-pyrantel pamoate

In systemic rheumatic disease, marker antibodies such as anti-Sm, anti Scl-70 and anti Jo-1 are helpful in the diagnosis of disease, but in rheumatoid arthritis, the diagnosis is difficult due to the low sensitivity and specificity of the rheumatoid factor(RF). So, a new maker antibody with high sensitivity and specificity was needed. Recently, the antiperi- nuclear factor(APF) has gained particular attention. The results of the APF and RF test in 165 patients with rheumatoid arthritis, 77 patients with osteoarthritis, and 109 normal healthy persons, which were taken between January, 1994 through December 1994 were as follows; 1. The sensitivity, specificity, and predictive value of positivity of the RF test in patients with rheumatoid arthritis were 58.2%, 93.5%, and 95.0%, and that of the APF test were 72.1%, 94.6% and 92.2%, respectively. 2. The sensitivity, specificity and predictive value of positivity when combining the APF with the RF were 83.0%, 85.7%, and 92.6%, respectively. 3. The disease status of the patients correlated with intensity of the APF test, that is, the more severe the disease status, the higher intensity. In conclusion, the APF was useful in the diagnosis of rheumatoid arthritis, and may be used as an indicator of disease status. When combining test the APF with RF, the incidence of sero-negative rheumatoid arthritis decreased.
Antibodies ; Arthritis, Rheumatoid ; Diagnosis ; Humans ; Incidence ; Osteoarthritis ; Rheumatic Diseases ; Sensitivity and Specificity

Interposition arthroplasty of the hip is to create a new joint by interposing an inert and durable substance between the reshapened ends of the femoral head and acetabulum, usually for the treatment of the primary and secondary osteoarthritis of the hip. The major goals of arthroplasty of the hip are to relieve pain, restore joint motion, correct deformity, and to provide stability of the joint. We reviewed the follow-up results of 23 Smith-Patersen vitallium cup arthroplasties in a consecutive series of 20 patients with various arthritides of the hip, who were treated at the National Medical Center between January 1962 and December 1970. Average duration of follow-up was 2 year and 10 months. 1. Male to female ratio was 12:8. Average of the patients was 30 years. 2. Seven patients had rheumatoid arthritis or ankylosing spondylitis and five patients had ankylotic hips. Three patients had primary osteoarthritis and another three osteoarthritis secondary to Legg-Calve-Perthes disease. There were one case each of tuberculous arthritis and traumatic dislocation. 3. Average duration of admission was 7 weeks. 4. Weight bearing was started gradually at 12 weeks post-operatively in majority of the cases. 5. Over-all results of the 20 patients were satisfactory in 12 (60%), and unsatisfactory in 8 (40%). 6. Results of cup arthroplasty in patients with primary osteoarthritis and osteoarthritis secondary to Legg-Calve-Parthes disease were satisfactory in all 6 cases, but were unsatisfactory in 5 out of the 7 cases of the rheumatoid arthritis and ankylosing spondylitis. 7. Three patients with bilateral cup arthroplasties yielded poor results. 8. Complications included eight infections and one each of early dislocation of the cup and periarticular new bone formation.
Acetabulum ; Arthritis ; Arthritis, Rheumatoid ; Arthroplasty ; Congenital Abnormalities ; Dislocations ; Female ; Follow-Up Studies ; Head ; Hip ; Humans ; Joints ; Legg-Calve-Perthes Disease ; Male ; Osteoarthritis ; Osteogenesis ; Spondylitis, Ankylosing ; Vitallium ; Weight-Bearing

No abstract available.
Pancreaticoduodenectomy*

PURPOSE: To compare the lamina cribrosa thickness in fellow eyes of patients with unilateral retinal vein occlusion (RVO) with the normal control eyes and the type of RVO. METHODS: This study included 40 patients with unilateral RVO and 45 normal control subjects. We compared the lamina cribrosa thickness between the RVO eyes and the fellow eyes, the fellow eyes and the normal control eyes and the type of RVO eyes. We measured central lamina thickness using enhanced depth imaging spectral-domain optical coherence tomography. RESULTS: In patients with unilateral RVO, central lamina cribrosa thickness was not significantly different between the RVO eyes (211.33 microm) and the fellow eyes (204.13 microm; p = 0.202). However, central lamina cribrosa thickness in the fellow eyes was significantly reduced compared with the normal control eyes (217.76 microm; p = 0.046). Central lamina cribrosa thickness in the fellow eyes according to the type of RVO was not statistically significantly different (p = 0.672). CONCLUSIONS: This study showed that the central lamina cribrosa thickness in the fellow eyes of patients with unilateral RVO was thinner than in normal patients. Therefore, the lamina cribrosa thickness may be associated with RVO as well as glaucoma.
Glaucoma ; Humans ; Retinal Vein Occlusion* ; Retinal Vein* ; Retinaldehyde* ; Tomography, Optical Coherence

No abstract available.
Arthroplasty, Replacement, Hip*

This study was performed to observe the retinal changes in rabbits by intravitreal inoculation of HSV-1. The solution of HSV-1 virus(Kos strain) was inoculated into the vitreous cavity in 5 eyes. All the eyes were checked with a slit lamp and an indirect ophthalmoscope. Two eyes that showed the retinal lesion were enucleated for the histopathologic examination. The focal infiltration of inflammatory cells was marked around the retinal vessels in one eye and there was the diffuse infiltration of plasma cells and lymphocytes in the choroid and the retina in the other eye. The pattern of proliferation and migration of retinal pigment epithelial cells was observed at the outer retina. The virus-infected nuclei were evident in the photoreceptor cells and ganglion cells. The viral particles and intranuclear inclusion were prominent in the deformed nuclei and free-floating viral particle was shown at the extracellular space of the necrotic retina. These results suggest that the intravitreal inoculation of HSV-1 might induce retinal necrosis. The inflammatory reactions was initiated at the vitreoretinal interface and perivascular area. Virus might be propagated through axons or infected cell from free-flating virus.
Axons ; Choroid ; Epithelial Cells ; Extracellular Space ; Ganglion Cysts ; Herpes Simplex* ; Herpesvirus 1, Human ; Intranuclear Inclusion Bodies ; Lymphocytes ; Necrosis* ; Ophthalmoscopes ; Photoreceptor Cells ; Plasma Cells ; Rabbits ; Retina ; Retinal Vessels ; Retinaldehyde* ; Simplexvirus ; Virion