1.Endocrine Disrupters and Reproduction.
Chang Joo LEE ; Ho Joon LEE ; Yong Dal YOON
Journal of Korean Society of Endocrinology 2001;16(6):596-623
No abstract available.
Reproduction*
2.Imbalance in T Lymphocyte Subsets in Erythema Nodosum Leprosum.
Hyang Joon PARK ; Chang Yong CHA ; Woo Hyun CHANG ; Do Il KIM
Korean Journal of Dermatology 1987;25(4):476-485
A study was performed to investigate a relationship between the status of T lymphocyte subsets in the peripheral blood and the pathogenesis of erythema nodosum leprosum (ENL) reactions. T lymphocyte subsets, B lymphocytes and serum immnnoglobulin levels were explored in 40 leprosy patients (10 tuberculoid (TT), 17 lepromatous (LL), and 13 lepromatous with ENL). In patients with LL, suppressor cells increased and helper cell diminished, resulting in a decrease in the helper/suppressor (Th/Ts) ratio to 0.86 + 0.20, as compared with controls (1. 77 + 0.41). But in ENL patients, there was a significant diminution of suppressor cells and an increase of helper cells, resulting in an increase in Th/Ts ratio to 2.08 + 0.30. Four weeks after treatment of ENL, Th/Ts ratio decreased to l.18+ 0.31 again. The mean percentages of B cells and serum immunoglobulin levels in with LL. and ENL increased significantly compared with controls. Only IgG increased in patients with ENL compared with patients with LL. The results in patiients with TT did not differ significantly from those of controls. The findings suggest that cell-mediated immune responses, imbalance in T lymphocyte subsets, may play a role in the pathogenesis of ENL, either directly or by inducing an antibody critical to the formation of the immune complex
Antigen-Antibody Complex
;
B-Lymphocytes
;
Erythema Nodosum*
;
Erythema*
;
Humans
;
Immunoglobulin G
;
Immunoglobulins
;
Leprosy
;
T-Lymphocyte Subsets*
;
T-Lymphocytes, Helper-Inducer
3.Malignant gastric leiomyoma.
Chang Joon AHN ; Cho Hyun PARK ; Jong Seo LEE ; Joon Gi KIM ; Sang Yong CHOO ; Rae Sung KANG ; In Chul KIM
Journal of the Korean Surgical Society 1993;45(2):199-208
No abstract available.
Leiomyoma*
4.A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood.
Yeong Ho RA ; Sung Ho CHA ; Sa Joon CHUNG ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1987;30(7):759-768
No abstract available.
Humans
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pneumonia*
;
Pneumonia, Mycoplasma*
5.Correlation of Endoscopic Redness with Histological Findings in Superficial Gastritis.
Joon Mo CHUNG ; Yong Hwan CHOI ; Sung Kook KIM ; Chang Hyeong LEE ; Young Ok KWEON
Korean Journal of Gastrointestinal Endoscopy 1995;15(4):664-669
Superficial gastritis has been classified as a type of chronic gastritis, since a report of Schindler in GASTRLTIS, 1947. Howev~er, Benedict reported that superficial gastritis is only acute gastritis or shows normal mucosa histologically. The com mon endopical findings of chronic superficial gastritis were adherent mucus, edema, redness. The common redness which were encounterd are patchy redness and comb-like redness(Kammrotung). We studied the relationship between the redness of superficial gastritis and acute inflammatory changes histologically. Each case of superfieial gastritis was biopsied to redening and non-redening mucosa respectively. We collected 24 cases with 48 biopsy specimens. The results are as follows: Acute inflammatory changes were found only one case in redness and none in non-redness groups. There was no difference in acute inflammatory changes in two groups. The degree of mucosal atrophy were 62.5%, 66.7% in normal mucosa, 12.5%, 16.7~% in mild atrophy, 25%, 12.5% in moderate atrophy, 0%, 4.l% in severe atrophy with respect to redness and non-redness mucosa respectively. There was no difference in degree of mucosal atrophy in two groups. Mucosal atrophies were higher in older ages above 41 years old than below 40 and with increasing age, there was increasing tendency of mucosal atrophy. In conclusion, There was no relationships between mucosal redness and acute in flammatory changes histologically and also between mucosal redness and degree of atrophy.
Adult
;
Atrophy
;
Biopsy
;
Edema
;
Gastritis*
;
Humans
;
Mucous Membrane
;
Mucus
6.Dermatomyositis Associated with Stomach Cancer.
Yong Joon KIM ; Seong Jun SEO ; Chang Kwun HONG ; Byung In RO
Korean Journal of Dermatology 1997;35(1):174-178
A 62 year old man had skin eruptions, general weakness, swallowing difficulty, and fever for 3 months. Diagnosis of dermatomyositis was established on the bases of clinical manifestations, muscle enzyrne study, electromyogram and histopathological findings of skin and muscle. Borrman type g stomach cancer was found by gastroendoscopy and computed tomography. He refused surgical operation for stomach cancer and died 2 months later.
Deglutition
;
Dermatomyositis*
;
Diagnosis
;
Fever
;
Humans
;
Middle Aged
;
Skin
;
Stomach Neoplasms*
;
Stomach*
7.Balloon Catheter Dilatation in Esophageal Achalasia: Long Term Follow-Up.
So Eun KIM ; Shin Hyung LEE ; Chang Joon LEE ; Cheol Yong SHIN ; Hyun Mee PARK
Journal of the Korean Radiological Society 1994;31(6):1039-1044
PURPOSE: To evaluate the clinical efficacy of balloon catheter dilatation in the treatment of esophageal achalasia. MATERIALS AND METHODS: Seven patients(three males and four females) with esopha-geal achalasia were treated with balloon catheter dilatation. Balloon catheters of variable sizes were used depending on patient's conditions. The patients were followed up over a period of 12-39months. RESULTS: Balloon catheter dilatation in esophageal achalasia was successful in all patients without esophageal perforation. All patients were relieved from dysphagia. Recurrence was not found in 5 patients on long term follow-up study, but was seen in 2 patients after 18 and 21 months, respectively. CONCLUSION: Balloon catheter dilatation was a safe and effective method in the treatment of esophageal achalasia with low recurrence rate of 29% on follow-up study.
Catheters*
;
Deglutition Disorders
;
Dilatation*
;
Esophageal Achalasia*
;
Esophageal Perforation
;
Follow-Up Studies*
;
Humans
;
Male
;
Recurrence
9.Prognosis of Complete Transposition on the great Arteries.
Yong Soo YUN ; Chang Yee HONG ; Joon Ryang RHO ; Chong Whan KIM ; Kyung Phil SUH
Journal of the Korean Pediatric Society 1985;28(12):1177-1183
No abstract available.
Arteries*
;
Prognosis*
10.The change of anti-HBs titer after hepatitis B vaccination in newborn according to dosage and time.
Joon Young LEE ; Yong Sik MIN ; Chang Hwi KIM ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1993;36(5):656-663
We studied anti-HBs titer, positive and effective rate in relation to dosages(5microgram, 10microgram) and time interval after third vaccination in 23 infants born to HBsAg negative mother. The babies were divided into two groups. In one group(n=12), 5microgram of Hepavax was administered intramusculary at 1 month, 2 months and 6 months of age, in other group (n=11), 10microgram of Hepavax at same time interval. And the anti-HBs was studied at 2 months and 3 year after third vaccination by radioimmunoassay. The results were as follows: 1) The anti-HBs positive rate was 100% in two groups at 2 months and 3 years after vaccination. 2) The geometric mean anti-HBs titer at 2 months after third vacciantion was 9418.3+/-13041.5 IU/L in 5microgram group and 12750.0+/-12750.5 IU/L in 10microgram group, and 3 year after vaccination, 949.4+/-1404.0 IU/L in 5microgram group, 1067.4+/-1067.7 IU/L in 10microgram group. There were no significant difference between two groups, although mean anti-HBs titer decreased significantly after 3 years. 3) The effective rate at 3 years after vaccination was 66.7% in 5 microgram group and 72.8% in 10microgram group. There was no statistical significant difference between two groups.
Hepatitis B Surface Antigens
;
Hepatitis B Vaccines
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Infant
;
Infant, Newborn*
;
Mothers
;
Radioimmunoassay
;
Vaccination*