1.The Clinical Study of Non-union of Phalages in the Hand
Key Yong KIM ; Duck yun CHO ; Sam Joo KWON
The Journal of the Korean Orthopaedic Association 1986;21(2):353-358
Fractures of the phalanges of the hand are very common. Many are minor and likely to have a good result. However many other phalangeal fractures cause significant and prolonged disability. Non-union of the tubular bones of the hand are uncommon occurrence, but are often associated with functional deficits. The authors have reviewed 7 cases of non-union of the phalanges which were treated in the department of orthopaedic surgery, National Medical Center from 1978 to 1985. The results were summarized as follows: 1. The non-union of phalangeal bone was defined by clinical symptoms and signs and roentgenological examination. 2. The incidence of non-union of phalangeal bone fractures was 0.9% (7/771 cases.) 3. of 7 patients, there were 6 in male and 1 in female. 4. Non-union occurred more commonly in the second decade and the group between 10 and 30 years of age. 5. Seven cases, all were the right handed, but injury was developed in the left hands except two cases. 6. The causes of non-union were thought as open wound (7 cases), type of fracture (simple or comminution:3 cases), inadequate immobilization (4 cases) and overtraction (1 case). 7. of 7 cases, 4 cases were treated with bone peg graft and K-wire fixation and 2 cases with excision of distal fragment. 8. The clinical union was 9 weeks in average.
Clinical Study
;
Female
;
Fractures, Bone
;
Hand
;
Humans
;
Immobilization
;
Incidence
;
Male
;
Transplants
;
Wounds and Injuries
2.Pre-diagnostic Clinical Presentations and Medical History Prior to the Diagnosis of Inflammatory Bowel Disease in Children.
Pediatric Gastroenterology, Hepatology & Nutrition 2013;16(3):178-184
PURPOSE: The clinical presentations of inflammatory bowel disease (IBD) prior to diagnosis are so diverse or vague that many of them waste time before final diagnosis. This study was undertaken to know the medical history of the pediatric patients until the final diagnosis could be reached. METHODS: The medical records of all pediatric patients who were diagnosed with IBD (Crohn's disease [CD] in 14 children, ulcerative colitis [UC] in 17) during the last 13 years were reviewed. We investigated the length of the diagnostic time lag, chief clinical presentation, and any useful laboratory predictor among the routinely performed examinations. Indeterminate colitis was not included. RESULTS: The mean ages of children at the final diagnosis was similar in both diseases. As for the pre-clinical past history of bowel symptoms in CD patients, 5 were previously healthy, 9 had had 1-3 gastrointestinal (GI) symptoms, weight loss, bloody stool, anemia and rectal prolapse. With UC, 9 were previously healthy, 8 had had 1-3 GI symptoms, bloody stool, anorexia. The average diagnostic time lag with CD was 3.36 months, and with UC 2.2 months. Body mass index (BMI) and the initial basic laboratory data (white blood cell, hemoglobin, mean corpuscular volume, serum albumin, and serum total protein) were lower in CD, statistically significant only in BMI. CONCLUSION: IBD shows diverse clinical symptoms before its classical features, making the patients waste time until diagnosis. It is important to concern possibility of IBD even in the mildly sick children who do not show the characteristic symptoms of IBD.
Anemia
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Anorexia
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Blood Cells
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Body Mass Index
;
Child
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Colitis
;
Colitis, Ulcerative
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Erythrocyte Indices
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Humans
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Inflammatory Bowel Diseases
;
Medical Records
;
Rectal Prolapse
;
Serum Albumin
;
Weight Loss
3.Comparison of Rectoanal Physiologic Changes and Treatment Results between Transanal Repair and Transanal Repair with Posterior Colporrhaphy in Patients with Rectocele.
Joo Hyung KIM ; Young Min KWON ; Yong Pyo LEE
Journal of the Korean Society of Coloproctology 2004;20(2):86-92
PURPOSE: Rectoceles are often associated with anorectal symptoms. Various surgical techniques have been described to repair rectoceles, but the surgical results vary. The aim of this study was to compare transanal repair (TAR) and transanal repair with posterior colporrhaphy (TAR+PC). METHODS: The records of 58 patients operated on during a 56-month period were reviewed. Of those 26 patients had a TAR, and 32 patients had a TAR+PC. Interviews and anorectal physiologic studies were performed preoperatively and postoperatively. RESULTS: The recurrence rate after a TAR+PC was lower than the recurrence rate after a TAR (TAR 19.2% vs. TAR+PC 3.1%). The rectal sensation (sensory threshold: TAR 64.8+/-18.9 ml vs. TAR+PC 56.1+/-23.67 ml; earliest defecation urge: TAR 116.4+/-29.5 ml vs. TAR+PC 104.8+/-31.2 ml) was more improved after a TAR+PC. CONCLUSIONS: A TAR+PC for treatment of a rectocele is safe and effectively corrects obstructed defecation. The improvement probably relates, at least in part, to rectal sensational factors other than the dimensions of the rectocele.
Defecation
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Humans
;
Rectocele*
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Recurrence
;
Sensation
4.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
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Immunity, Cellular*
;
Immunoglobulin A*
5.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
;
Immunity, Cellular*
;
Immunoglobulin A*
6.The Prospective Study of Anorectal Physiologic Change after Transanal Repair in Rectocele.
Joo Hyung KIM ; Young Min KWON ; Yong Pyo LEE
Journal of the Korean Society of Coloproctology 2002;18(4):216-221
PURPOSE: Generally, the constipation is a medical disease, but recently, there are many reports showing the good results after correction of rectocele in constipated patients. The authors try to show the effect of surgery in rectocele cases and also analyse the relationship between the anatomical distortion and clinical symptoms by using anorectal physiologic study before and after operation. METHODS: 31 cases of rectocele are surgically corrected from June 1998 to August 2001. 31 cases of them could be followed up and with them, pre- and post-operative anal ultrasonography, anorectal manommetry and defecography were tried. Personal interview was also done to each patient. RESULTS: After trasanal rectocele repair, the rectocele size decreased and clinical symptoms improved remarkably. In defecography, anorectal angle (pre-op; 105.9+/-6.0 degrees vs. post-op; 109.5+/-3.7 degees) and perineal descent (1.6+/-0.7 cm vs. 2.4+/-1.2 cm) increase in pushing state after operation. In anorectal manometry, mean resting anal pressure (29.2+/- 3.4 mmHg vs. 17.9+/-4.6 mmHg) and maximal squeeze pressure (84.5+/-20.8 mmHg vs. 47.6+/-12.1 mmHg) decreased and rectal sensation improved after operation. CONCLUSIONS: Current results suggest that the surgical correction aims not only the decrement of the rectocele size but changing the vector power on pushing more physiologically and also improving the rectal sensibility.
Constipation
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Defecography
;
Humans
;
Manometry
;
Prospective Studies*
;
Rectocele*
;
Sensation
;
Ultrasonography
7.The effect of systemic nifedipine pretreatment on renal function & plasma renin activity in experimental ischemic acute renal failure.
Won Choong CHOI ; Dae Ryong CHA ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM
Korean Journal of Nephrology 1991;10(4):534-544
No abstract available.
Acute Kidney Injury*
;
Nifedipine*
;
Plasma*
;
Renin*
8.The Sequential Change of Isotope Uptake Ratio in Femur Neck Fracture
Key Yong KIM ; Yung Tae KIM ; Hyung Ku YOON ; Sam Joo KWON
The Journal of the Korean Orthopaedic Association 1987;22(2):425-432
In spite of recent development in fixation technique we still have lots of complication including avascular necrosis of femoral head. For many years, orthopaedic surgeon have been searching for a simple, safe, accurate and reliable clinical test to asses the vascular status of the femoral head. In early detection of viability of the femoral head, nothing is more certain than bone scan at the moment. Bone scan can detect or predict the viability of the femoral head. Subramanian and McAfee introduced 99mTc-Sn-polyphosphate as a bone seeking agents. We applied serial bone scan in 19 cases of femur neck fractures from 1982 to 1985 at the department of orthopaedic surgery, National Medical Center. The results were as follows; 1. The uptake ratio of displaced and undisplaced group based on preoperative radiography was 1.ZO, 1.46, 1.52, 1.55, and 0.63, 1.23, 1.81, 1.58 in average in postoperative bone scan interval 1–2 wks, 3 months, 6 months, 12 months. The bone scan uptake ratio was lower in the former than the latter, but after 3 months, there was no remarkable difference between them. 2. At the time of 1 to 2 weeks, 3 months, 6 months and 12 months, uneventful group was 0.74, 1.27, 1.72, 1.62 and avascular necrosis group 0.13, 0.18, 0.30, 0.67 in the uptake ratio. In 2 cases of avascular necrosis, the uptake ratio was markedly decreased. 3. There was no difference between the group operated within 48 hour after injury and the group delayed later.
Equidae
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Femoral Neck Fractures
;
Femur Neck
;
Femur
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Head
;
Necrosis
;
Radiography
9.The effects of chromium exposure on sister chromatid exchange and concentration of 8-hydroxydeoxyguanosine.
Sang Hwan HAN ; Soo Hun CHO ; Heon KIM ; Soo Min PARK ; Mina HA ; Young Soo JOO ; Ho Jang KWON ; Yong Dae KWON ; Myung Hee KWON
Korean Journal of Preventive Medicine 1995;28(2):511-525
To elucidate some DNA adducts as a biological marker for workers of chromate pigment, the effects of chromium exposure on the formation of 8-hydroxydeoxyguanosine(8-OH-dG) and sister chromatid exchanges(SCEs) frequency in 38 workers of a pigment plant in Bucheon which utilized lead chromates, were examined. The chromium contents of venous blood and urine were measured as working environmental exposure level. The concentrations of 8-OH-dG in DNA isolated from lymphocytes were determined with high performance liquid chromatography and electrochemical detector and denoted as a molar ratio of 8-OH-dG to deoxyguanosine(dG). The SCEs frequency were analyzed in DNA isolated from lymphocytes. A significant correlation was found between creatinine adjusted urine chromium concentration and the molar ratio of 8-OH-dG to dG(r=0.47, p<0.01). After adjusting the current smoking habit, the correlation coefficient was increased(r=0.62, p<0.05). However, there was no significant correlation between the SCE frequency and chromium exposure. This significant results between molar ratio of 8-OH-dG to dG and chromium exposure are in good agreement with in vitro studies that support the importance of DNA adduct formation for the carcinogenic effect of chromium.
Biomarkers
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Chromates
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Chromatids
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Chromatography, Liquid
;
Chromium*
;
Creatinine
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DNA
;
DNA Adducts
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Environmental Exposure
;
Gyeonggi-do
;
Humans
;
Lymphocytes
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Molar
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Plants
;
Siblings*
;
Sister Chromatid Exchange*
;
Smoke
;
Smoking
10.A Case of Esophageal Candidiasis in an Adolescent Who Had Frequently Received Budesonide Nebulizing Therapy.
Hae Ryong KANG ; Yong Hoon KWON ; Yong Joo KIM
Pediatric Gastroenterology, Hepatology & Nutrition 2013;16(3):185-189
Corticosteroid (budesonide) nebulizer therapy is commonly performed. Its side effects have been considered as being safe or ignorable. The authors present a case of esophageal candidiasis in a healthy female adolescent who was treated with budesonide nebulizer therapy a few times for a cough during the previous winter season. This child presented with dysphagia and epigastric pain for 1 month. Esophageal endoscopy showed a whitish creamy pseudomembrane and erosions on the esophageal mucosa. Pathologic findings showed numerous candidal hyphae. She did not show any evidence of immunodeficiency, clinically and historically. The esophageal lesion did not resolve naturally. The esophageal lesion completely improved with the antifungal therapy for 2 weeks; the symptoms disappeared, and the patient returned to normal health. It is important that frequent esophageal exposure to topical corticosteroids application can cause unexpected side effects.
Adolescent
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Adrenal Cortex Hormones
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Budesonide
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Candidiasis
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Child
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Cough
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Deglutition Disorders
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Endoscopy
;
Esophagus
;
Humans
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Hyphae
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Mucous Membrane
;
Nebulizers and Vaporizers
;
Seasons