1.How we diagnose and treat chronic lymphocytic leukemia.
Chinese Journal of Hematology 2018;39(7):529-532
6.Ischemic Tolerance and Expression of Hypoxia Inducible Factor-1? in PC12 Cells Induced by Acanthopannx Senticosus Saponins
jian, CHEN ; li, ZHU ; yong-jin, PAN
Journal of Applied Clinical Pediatrics 2006;0(24):-
Objective To study ischemic tolerance induced by acanthopannx senticosus saponins(ASS) on ischemia in PC12 cells and involve expression of hypoxia inducible factor-1?(HIF-1?).Methods An ischemic model was developed in PC12 cell line with treatment of oxygen glucose deprivation(OGD).The protective effects of ASS pretreatment on ischemic tolerance of PC12 cells and whether protective effects of ASS could be inhibited by LY294002(PI3K inhibitor) were analyzed through MTT assay.The induction of phospho-glycogen synthesis kinase-3?(p-GSK-3?) and HIF-1? after pretreatment of ASS and possible blocking effects of LY294002 were detected by Western-blot.Results MTT results showed that after 9 h ischemia,the viability of PC12 cells decreased dramatically(P
7.Continuous intravenous infusion of midazolam for treatment of status epilepticus in children.
Jian-min ZHONG ; Jian-hua LI ; Yong CHEN
Chinese Journal of Pediatrics 2004;42(4):299-300
Adolescent
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Age Factors
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Anti-Anxiety Agents
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administration & dosage
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adverse effects
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therapeutic use
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Infusions, Intravenous
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Male
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Midazolam
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administration & dosage
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adverse effects
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therapeutic use
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Status Epilepticus
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drug therapy
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Treatment Outcome