No abstract available.
Nephrotic Syndrome*

No abstract available.
Adult* ; Head* ; Humans

Tumor suppressive effect of dehydroepiandrosterone (DHEA) on the experimentally induced hepatocellular carcinoma was investigated, especially focusing on glutatione transferase and transglutaminase with aptosis in the carcinogenesis. The chemical hepatocarcinogenic procedure of Solt-Farber method was used on Sprague-Dawley rats. Experimental groups were divided into AA group treated by the standard Solt-Farber regimen of diethylnitrosamine (DEN) and 2-acetamidofluorene (AAF) and AD group treated with DHEA simultaneously with AAF and the AAD group treated by DHEA after treatment with AAF. Each group was divided by time sequence further into four subgroups, GI (8wk), G2 (16wk), G3 (28wk), and G4 (36wk). For neoplastic lesion, the immuno histochemical study with anti GSTP antibody was carried out, while the activity and expression of TGase was compared at the same time. The results were summarized as follows; GST-P positive foci detected in AD groups were significantly more suppressed by DHEA treatment than AA groups (P<0.05). AD groups. AD group showed higher activities of TGase than AA groups (P<0.05), which was confirmed by Western and Northern blot analysis. But the number of apoptotic bodies was not correlated with activity and expression of TGase in the nodule. These results suggest that the suppressive effect of DHEA on the murine hepatocellular carcinogenesis might be operating on the promotion process of carcinogenesis rather than regression process of transformed hyperplastic nodules.
Carcinoma, Hepatocellular

No abstract available.
Granuloma* ; Leprosy, Lepromatous*

BACKGROUND: The aim of the present study was to determine the correlation between the amount of pain reduction after local anesthetic injection into the subacromial space preoperatively and clinical outcome after arthroscopic rotator cuff repair. METHODS: A total of 127 patients who underwent arthroscopic rotator cuff repair and followed up at least 1 year were analyzed retrospectively. Preoperatively, a visual analogue scale (VAS) for pain was measured in all patients before and after the ultrasound guided impingement test. The participants were divied into four groups according to pain reduntion ater impingement test (Group A: >75%, Group B: 50%–75%, Group C: 25%–50%, Group D: <25%). VAS for pain, shoulder range of motion, shoulder isometric strength, ASES score were evaluated preoperatively and at 3, 6, 9, and 12 months postoperatively. RESULTS: After surgery, the amount of pain reduction shows significantly at 3, 6 months in Groups A, B as compared to Groups C, D (p<0.05). Among the range of motion of shoulder joint, forward flexion was significantly improved in Group A at 3 months (p<0.05). The ASES score significantly improved at 3, 6 months in Groups A, B as compared to Group C, D (p<0.05). CONCLUSIONS: Preoperative degree of pain reduction after impingement test correlates with the improvement of pain after arthroscopic rotator cuff repair, especially in the early phase. Therefore, the impingement test could be effectively used.
Humans ; Range of Motion, Articular ; Retrospective Studies ; Rotator Cuff* ; Shoulder ; Shoulder Joint ; Shoulder Pain ; Ultrasonography

PURPOSE: The purposes of this study was to evaluate an occupational health promotion program for the prevention of cardiovascular disease. METHOD: This study employed a quasi-experimental non-equivalent pre and post test to evaluate the program. The subjects of this study were 48 employees selected by convenience sampling who were suspected of having hypertension and hyperlipidemia in routine physical examinations and who were working in A University Hospital in Suwon. 25 subjects were assigned to the experimental group and 23 to the control group. Data collection was done using questionnaries before and after the subjects used the program. RESULTS: The results of this study showed that systolic blood pressure, ALT, gamma-GTP in the experimental group was lower than that of the control group. There were significant differences between two groups in the percentage of 'irregularity of diet' and in health behavior compliance. There were significant differences between the two groups in the number of complaints of symptoms after using the program. CONCLUSION: This study shows that there were no obvious differences between the two groups in all areas, but this program had a positive effect on health behavior changes. It is expected that employees' lifestyles can be changed through continuous health promotion programs.
Blood Pressure ; Cardiovascular Diseases* ; Compliance ; Surveys and Questionnaires ; Gyeonggi-do ; Health Behavior ; Health Promotion ; Hyperlipidemias ; Hypertension ; Life Style ; Occupational Health* ; Physical Examination

PURPOSE: The purpose of this study was to examine the psychometric properties of the Korean version of the General Practitioner Assessment of Cognition (K-GPCog) scale. METHOD: The K-GPCog consists of the 2 subscales, patients and caregivers. Using a sample of 412 community-based Korean older adults, internal consistency reliability was estimated using Cronbach's alpha. To evaluate validity of the K-GPCog, correlational analysis was conducted using Pearson r between K-GPCog and the Korean Dementia Screening Questionnaire (KDSQ). RESULTS: Cronbach's alpha coefficients of the K-GPCog patients' and caregivers' subscales .788 and .794 respectively. Pearson's correlation coefficients were r=-.374, r=-.481, and r=-.493, respectively for the subscales of patients and primary caregivers, and total K-GPCog. The degree of diagnostic agreement about the risk for cognitive disorders of older adults showed 11.7% and 11.2% respectively for the K-GPCog and the KDSQ. CONCLUSION: The findings provided preliminary evidence of the K-GPCog as a useful screening measure for detecting mild cognitive disorders of Korean older adults. The K-GPCog is particularly useful to identify cognitive disorders from primary caregivers when it is difficult to assess the level of cognition of older adults.
Adult ; Aged ; Caregivers ; Cognition ; Dementia ; General Practitioners ; Humans ; Mass Screening ; Psychometrics ; Surveys and Questionnaires

No abstract available.

No abstract available.
Cisterna Magna*

No abstract available.
Dermatitis, Atopic* ; Food Hypersensitivity ; Milk Hypersensitivity* ; Milk*