No abstract available.

Scabies may be seen in psoriatic patients, although not frequent. This situation provokes many problems including the difficulty of diagnosis and uncertainty of appropriate therapy. We report a case of a young female with an existing psoriasis aggravated following scabetic infestation. At first, she took an antiscabetic treatment but the severity of psoriasis persisted. Subsequently, cyclosporine treatment was started and the psoriatic lesions improved deamatically.
Cyclosporine ; Diagnosis ; Female ; Humans ; Psoriasis* ; Scabies* ; Uncertainty

Spontaneous subarachnoid hemorrhage(SAH) is a cause of high mortality and morbidity in the emergency department. Rebleeding has been well investigated, and it is now recognized that early operation can prevent rebleeding. However, ultra-early rebleeding, which may occur prior to early operation(within 24 hours after admission), worsens the clinical outcome of patients with SAH. To determine the risk factors of ultra-early rebleeding in patients with spontaneous SAH before early operation, we analyzed the cases of 383 patients admitted within 24 hours after their last attack of SAH between 1994 to 1996. In this analysis, diagnosis of rebleeding before admission was defined only if the patients experienced a definite clinical deterioration once more after an attack suggesting SAH. After admission patients who observed a sudden neurological deterioration were subject to repeat CT scanning and rebleeding was diagnosed only when new hemorrhage was observed on the CT scan in comparison with the previous scan. 45 cases(11.7%) of 383 patients had ultra-early rebleeding. The incidence of ultra-early rebleeding significantly increased in the patients who admitted hospital within 2 hours after attack. The incidence of ultra-early rebleeding also increased in the old-age group(70 years or more), patients with high systolic blood pressure, those who underwent angiography within 6 hours of the last SAH, and patients who had poor neurological condition.
Angiography ; Blood Pressure ; Diagnosis ; Emergency Service, Hospital ; Hemorrhage* ; Humans ; Incidence ; Mortality ; Risk Factors* ; Tomography, X-Ray Computed

Vitiligo is an acquired, disfiguring skin disease characterized by the loss of melanin, which results in depigmented areas of the skin. It affects at least 1% of the world's population. In countries where people are dark skinned, vitiligo is a major health problem. The pathogenesis of vitiligo has not been fully elucidated, but three possible origins, autoimmune, neurohumoral and self destruction of melanocyte, have been described. The clinical manifestations of vitiligo are well described in many reports. However in Korea, a few studies on the clinical features of vitiligo have been performed. Authors studied 217 Korean cases of vitiligo who had been visited at the Department of Dermatology, Kyung Hee University Hospital during the last 1 year (1978.4.1~1979.3.31). (countinued..)
Dermatology ; Korea ; Melanins ; Melanocytes ; Skin ; Skin Diseases ; Vitiligo*

Authors observed one case of subcutaneous dermoid cyst which did not seem to have been described in the Korean literature. A 11 year old female patient complained of a asymptomatic mass near the left sternoclavicular joint in January 1978. The mass was discovered at the age of 5 when that was pea-sized and had been slowly growing. In January 1978, the mass was palpable as a peanut-sized subcutaneous solitary round mass, and overlying skin was freely movable and slightly elevated. There was no trauma history and family history was negative except her elder sister had a, axillary accessory breast. Histopathologic studies revealed a keratinizing stratified squamous epithelium lining the cystic wall, and sebaceous glands, hair follicle and eccrine glands in the surrounding tissues, and keratinous materials in the cyst. There was no evidence of malignancy. Diagnosis was confirmed by clinical features and histopathological findings, and surgical excision of tumor mass was performed.
Breast ; Child ; Dermoid Cyst* ; Diagnosis ; Eccrine Glands ; Epithelium ; Female ; Hair Follicle ; Humans ; Sebaceous Glands ; Siblings ; Skin ; Sternoclavicular Joint

Ancient (degenerated) schwannomas are benign tumors that display pronounced degenerative changes including cyst formation, calcification, hemorrhage, and hyaliniz ation. The tumors are usually infiltrated by large numbers of inflammatory cells such as neutrophils, lymphocytes, siderophages, and histiocytes. They are located in deep locations such as the retroperitoneum and must be differentiated from malignant soft tissue tumors because spindle cells with nuclear atypia may be present in the fine needle aspiration biopsy. The cytologic findings of two cases of ancient schwannoma occurring in posterior mediastinum and retroperitoneum, respectively, are described. Computerized tomographic findings of both cases showed changes of cystic degeneration or necrosis. A case occurred in retroperitoneum revealed features of destruction of vertebral body to suggest a malignant soft tussue tumor radiologically. The cytologic findings of aspiration biopsy of both tumors revealed that the tumor cells were spindle in shape with elongated nuclei. Some of tumor cells were arranged in a palisading fashion. Cell structures that resemble the Verocay bodies were observed. Some of the tumor cells showed pleomorphic bizarre nuclei, but no mitotic activity or chromatin clumping was seen. Inflammatory cells, siderophages and histiocytes were scattered in fibrillar material. These cytologic findings are important in the diagnosis of ancient schwannoma and in the differentiation of this tumor from the malignant spindle cell tumor.
Biopsy ; Biopsy, Fine-Needle ; Biopsy, Needle ; Child* ; Chromatin ; Diagnosis ; Hemorrhage ; Histiocytes ; Humans ; Lymphocytes ; Mediastinum ; Methylprednisolone* ; Necrosis ; Nephrotic Syndrome* ; Neurilemmoma ; Neutrophils

No abstract available.
Child* ; Glomerulonephritis, Membranoproliferative* ; Humans

We report a case of neuroblastoma with multiple skin metastases as a chief complaint in a 2-month-old girl. the skin lesions were rnultiple, pea-sized, bluish, nontender, moable subcutaneous nodules on abdomen, back and scalp. Histopathology showed small round or poly gonal tumor cells which have deeply stained, basophilic, hyperchromatic nuclei with some mitoses. Th.se tumor cells showed clumping tendency which is one of early menifestations of rosette formation. Immunohistochemically positive reaction was demonstrated by anti-NSE(neuron specific enolase) antilody but negative reaction by anti-NFP (neurofilament proteiin ) antibody. She has been succesfully treated with combined chemotherapy for 10 months without relapse.
Abdomen ; Basophils ; Drug Therapy ; Female ; Humans ; Infant ; Mitosis ; Neoplasm Metastasis* ; Neuroblastoma* ; Phosphopyruvate Hydratase ; Recurrence ; Rosette Formation ; Scalp ; Skin*

BACKGROUND: For the evaluation of pulmonary nrtery branches after operation of right ventricular outflow obstructive disease, we reviewed the usefulness of both simple X-ray and lung perfusion scan with 99mTc-macroaggregated albumin compared with cardiac angiography. METHODS: From March, 1986 to July, 1993, at Seoul National University Children;s Hospital, we chose 23 cases who underwent both simple X-ray and cardiac angiography among the patients who had distinct difference between right and left pulmonary blood flow in lung perfusion scan after operation of right ventricular outflow obstructive disease. So we calculated the ratio of right and left pulmonary blood flow and Spearman correlation coefficient. RESULTS: Of the 23 cases, 17 cases were tetralogy of Fallot, 4 cases pulmonary atresia, 1 case double outlet right ventricle, and 1 case truncus arteriosus. The mean age at poeration was 27 months, and the mean postoperative follow-up period was for 68 months. The correlation coefficient between cardiac angiography and simple X-ray was 0.86(p<0.01), and that beteen cardiac angiography and lung perfusion scan was 0.80(p<0.01). CONCLUSION: The cardiac angiography has been known as the best diagnostic tool for the evaluation of pulmonary artery branches after operation of right ventricular outflow obstructive ddisease, but we proposed that the lung perfusion scan should be widely used because its results were similar with those of cardiac angiography.
Angiography ; Double Outlet Right Ventricle ; Follow-Up Studies ; Humans ; Lung* ; Perfusion* ; Pulmonary Artery* ; Pulmonary Atresia ; Seoul ; Tetralogy of Fallot ; Truncus Arteriosus

We report a case of hereditary angioedema in a 48-year old female patient. She experidenced facial edema and dyspnea 5 to 6 times for a year. Similar episodes developed on some members of her family, especially her sisters and father. We examined her and her sister's serum complement levels. The results showed decreased levels of C1 esterase inhibitor and C4, compared to normal levels. We treated the patient with danazol effectively.
Angioedemas, Hereditary* ; Complement C1 Inhibitor Protein ; Complement System Proteins ; Danazol ; Dyspnea ; Edema ; Fathers ; Female ; Humans ; Middle Aged ; Siblings