1.Sister chromatid exchange(SCE) and chromosome abberrations inFanconi's anemia..
Yong Wook JUNG ; Sung Ik CHANG ; Chang Gu HU
Korean Journal of Physical Anthropology 1991;4(2):137-144
No abstract available.
Anemia*
;
Chromatids*
;
Humans
;
Siblings*
2.Detection of leptoapiral DNA by nucleic acid hybridization with 32P-labeld probe.
Seok Yong KIM ; Woo Hyun CHANG ; Ik Sang KIM
Journal of the Korean Society for Microbiology 1991;26(4):329-335
No abstract available.
DNA*
;
Nucleic Acid Hybridization*
3.Comparative Study between Uncemented Proximal Filling Stem and Distal Filling Stem: A retrospective matched-pair study
Yong Ho KIM ; Jae Ik YOO ; Chang Uk CHOI
The Journal of the Korean Orthopaedic Association 1994;29(2):556-566
The authors performed a retrospective matched-pair study for 54 uncemented total hip arthroplasties which were performed in management of avascular necrosis of femoral head from July, 1989 to May, 1991 to investigate what kind of stem is better between Anatomic stem as a proximal filling stem and Harris-Galante stem as a distal filling stem. The results were as followings: 1. Clinical results of Anatomic group were slightly better than those of Harris-Galante group in terms of incidence of thigh pain, groin or buttock pain and final functional score of hip. 2. Incidence of radiolucency around femoral stem in Harris-Galante group was higher than that in Anatomic group, especially in zone I, V of anteroposterior view and in zone IV of lateral view, which were statistically significant(p < 0.05). 3. The incidence of vertical subsidence of femoral stem in Harris-Galante group was significantly higher than that in Anatomic group(p < 0.05) and the average distance of subsidence was 3.2mm. 4. The incidence of endosteal osteolysis and bone resorption in Harris-Galante group was higher than that in Anatomic group. 5. In overall view, clinical and radiographic results of Anatomic group were better than those of Harris-Galante group.
Arthroplasty
;
Arthroplasty, Replacement, Hip
;
Bone Resorption
;
Buttocks
;
Groin
;
Head
;
Hip
;
Incidence
;
Necrosis
;
Osteolysis
;
Retrospective Studies
;
Thigh
4.Tissue Pressure Changes following Tibia Fracture
Won Ho CHO ; Chang Ju LEE ; Jho Woong KANG ; Ik Yull CHANG ; Hyoung Yong SHIN
The Journal of the Korean Orthopaedic Association 1980;15(3):540-545
Delayed diagnosis of the compartmental syndrome and subsequent delay in performing the fasciotomy can result in needless loss of function and possible amputation of the involved extremity. Unfortunately early evidence of this syndrome is difficult to assess. A direct measurement of the tissue pressure within a closed compartment has been developed which provides physicians with reliable information for determining the need for fasciotomy. In the 27 cases of the tibia fracture, tissue pressure was measured directly by method of the needle manometer in the Department of Orthopedic Surgery, Han Kang Sung Sim Hospital from March, 1979 to August, 1979. The results were as follows: 1. The highest mean tissue pressure per hour was 28 mmHg in anterior compartment at 24 hours after trauma, and 28.4 mmHg in deep post compartment at the same hours. 2. The highest pressure measured in all cases was 38 mmHg in anterior compartment at 24 hours and 39 mmHg in deep posterior compartment at 48 hours after trauma. 3. The return of increased tissue pressure to less than 10 mmHg took 122.6 hours in anterior and 124.4 hours in deep posterior compartment. 4. Tissue pressre was higher when there was associated fibula fracture. 5. Tissue pressure was higher in displaced fractures than in undisplaced fractures. 6. Tissue pressure was higher when fracture was in its upper one-third. 7. Tissue pressure was higher in comminuted fracture than simple fracture.
Amputation
;
Delayed Diagnosis
;
Extremities
;
Fibula
;
Fractures, Comminuted
;
Methods
;
Needles
;
Orthopedics
;
Tibia
5.A case of congenital goiter with congenital hypothyroidism due to organification defect.
Ik Hee LEE ; Sung Yong JUNG ; Thi Hyung PARK ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1993;36(7):1002-1008
We experienced a case of congenital goiter with congenital hypothyroidism in 45 day-old male, who complained of respiratory difficulty and anterior neck mass. After admission, he was diagnosed congenital hypothyroidism by the clinical manifestations and laboratory tests including biochemistry, radioimmunoassay, radioisotope study, perchlorate discharge test, and bone radiography. We obtained positive finding at the perchlorate discharge test and found that his congenital goiter with congenital hypothyroidism was manifested by organification defect. We started treatment with L-thyroxine orally at 6th hospital day. The case was presented with brief review of literatures.
Biochemistry
;
Congenital Hypothyroidism*
;
Goiter*
;
Humans
;
Male
;
Neck
;
Radiography
;
Radioimmunoassay
;
Thyroxine
6.Anthelmintic effect of oxantel pamoate and pyrantel pamoate suspension against intestinal nematode infestations.
Han Jong RIM ; Chang Yong WON ; Sung Ik LEE ; Jung Kyoo LIM
The Korean Journal of Parasitology 1975;13(2):97-101
A total of 56 subjects with multiple nematode infections with T. trichiura, Ascaris, hookworms and Enterobius were treated with oxantel and pyrantel pamoate mixture in a paratable suspension(50 mg of each per ml). A single dose of 10 mg per kg body weight in each cured 100 per cent of 54 subjects with Ascaris, 97.1 per cent of 35 subjects with hookworms, 77.8 per cent of 36 with Enterobius and 73.2 per cent of 56 subjects with T. trichiura infestation. The mean egg per gram stool reduction rate in T. trichiura infection was 91.9%. Of the 31 subjects infected with Ancylostoma doudenale 96.8% were cured with a single dose and 4 infected with Necator americanus showed a 100% cure rate with a similar daily dose on 3 consecutive days. Side effects were few and mild. There was no clinical or laboratory evidence of drug toxicity. These findings show a single dose of oxantel and pyrantel pamoate mixture to be a highly effective and acceptable treatment for multiple infections with these nematodes.
parasitology-helminth-nematoda
;
Trichuris trichiura
;
Ascaris lumbricoides
;
hookworm
;
Enterobius vermicularis
;
chemotherapy-oxantel pamoate-pyrantel pamoate
7.MR Imaging of Intracranial Dural Arteriovenous Fistulae (Dural AVF).
So Yong CHANG ; Dong Ik KIM ; Yeong Kook CHO
Journal of the Korean Radiological Society 1997;37(1):17-24
PURPOSE: To describe the magnetic resonance (MR) findings of intracranial dural arteriovenous fistulae (DAVF) and associated venous hypertensive diseases, and to determine their diagnostic value. MATERIALS AND METHODS: MR Imagings of twelve cases of angiographically-proven intracranial DAVF were analyzed. The presence of signal voids, dilatation of involved dural sinus, the dilatation of the extra/intradural venous system, high signal intensity on T2 weighted image, cerebral edema, intracranial hemorrhage, and hydrocephalus were retrospectively analyzed. MR findings and angiographic classification were compared. RESULTS: In 11 of 12 patients (92%), MR revealed the location of DAVF. In five cases, these were cavernous, and in six, they were extracavernous; the locations of the latter were as follows: superior sagittal sinus (SSS), 4: torcula, 1; lateral sinus & SSS, 1. Except for the lateral sinus lesion, all the DAVF seen in thses 11 patients showed the presence of signal voids and dilatation of the involved dural sinus. Findings of associated venous hypertensive disease, namely dilatation of the superior ophthalmic vein and cortical venous system, cerebral edema, and high signal intensity on T2-weighted images were observed in three cavernous lesions (50%), but all extracavernous DAVF (100%) showed associated venous hypertensive disease. When the grade of angiographic classification was high and reflux of sinus blood to the cortical vein was seen on angiography, the MR findings of intracranial venous hypertension showed good correlation. CONCLUSION: The MR findings of DAVF include dilatation of the dural sinus and signal voids of feeding arteries and draining vein. Other findings which suggest intracranial venohypertensive disease are dilatation of the cortical and medullary vein, hydrocephallus, cerebral edema and intracranial hamorrhage. These and the angiographic findings correlate well and suggest that in the diagnosis of DAVF and the detection of intracanial venohypertension, MR is a non-invasivse technique which can be use be usefully employed before final diagnosis by angiography.
Angiography
;
Arteries
;
Arteriovenous Fistula
;
Brain Edema
;
Central Nervous System Vascular Malformations*
;
Classification
;
Diagnosis
;
Dilatation
;
Humans
;
Hydrocephalus
;
Hypertension
;
Intracranial Hemorrhages
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Superior Sagittal Sinus
;
Transverse Sinuses
;
Veins
8.Determining the Location of Urban Health Sub-center According to Geographic Accessibility.
Kun Sei LEE ; Chang Yup KIM ; Yong Ik KIM ; Youngsoo SHIM
Korean Journal of Preventive Medicine 1996;29(2):215-226
Decentralization to local governments and amending of Health center Law are to promote the efforts of health planning at the level of local agencies. In the health facility planning, it is important to take into account that what to be built, where to be located, how far should be service area and so forth, because health facilities are immovable, and require capital as well as personnel and consumable supplies. The aim of our study, answering to the question of 'where to be located?`, is to determine the best location of urban health sub-center. At the local level, planning is the matter of finding the best location of specific facility, in relation to population needs. We confine the accessibility, which is basic to location planning, to geographic one. Location-Allocation Model is used to solve the problem where the location is to maximize geographic accessibility. To minimize the weighted travel distance, objective function, Rk= aijwidij is used. Distances are measured indirectly by map measure-meter with l:25,000 Suwon map, and each potential sites, 10 administrative Dongs in Kwonson Gu, Suwon, are weighted by each number of households, total population, maternal age group, child age group, old age group, Relief for the livelihood, and population/primary health clinics. we find that Kuwoon-Dong, Seodun-Dong, Seryu3-Dong, according the descending orders, are best sites which can minimize the weighted distance, and conclude that it is reasonable to determine the location of urban health sub-center among those sites.
Child
;
Equipment and Supplies
;
Family Characteristics
;
Gyeonggi-do
;
Health Facilities
;
Health Facility Planning
;
Health Planning
;
Humans
;
Jurisprudence
;
Maternal Age
;
Politics
;
Urban Health*
9.Cytogenetic characteristics and oncogene study on gastric cancer in Korea.
Sung Ik CHANG ; In Jang CHOI ; Ihn Hwan LEE ; Dae Kwang KIM ; Yong Wook JUNG
Korean Journal of Anatomy 1991;24(1):70-85
No abstract available.
Cytogenetics*
;
Korea*
;
Oncogenes*
;
Stomach Neoplasms*
10.A case of paraquat poisoning in child.
Min Yong OUM ; Sung Ik CHO ; Young Chang KIM ; Hak Ju CHA ; Sang Jhoo LEE
Journal of the Korean Pediatric Society 1989;32(11):1540-1545
No abstract available.
Child*
;
Humans
;
Paraquat*
;
Poisoning*